Next Sequence

TechBio Founders #32: Cleaning the world out of polyethylene plastics by turning nature's enzymes into powerful plastic degradation engines with Eleonore Eisath, Founder at Beworm

loretta@thenextsequence.vc (Loretta TIOIELA, Eleonore Eisath) — Fri, 26 Jul 2024 12:00:00 +0000

Beworm is a biotechnological start-up facing the challenge of plastic pollution. Our goal is to develop a biotic recycling process that decomposes polyethylene, a commonly used material, into its building blocks. With the help of selected microorganisms and enzymes, the long hydrocarbon chain of polymers can be split up into shorter fragments, which can be reused as raw materials. This will transform a linear process into a circular process.

TechBio Founders #31: Decoupling energy from fuels and emissions by building a super-star on earth with Francesco Volpe and Martin Kupp, CEO and CSO at Renaissance Fusion

loretta@thenextsequence.vc (Francesco VOLPE, Martin KUPP, Loretta TIOIELA) — Fri, 21 Jun 2024 07:00:00 +0000

Renaissance Fusion is a fusion energy company on a mission to decouple energy from fuels and emissions by building stellarators, the most efficient, steady, and stable fusion reactors on earth.

TechBio Investors#5-Xavier Mesnier & Perman Jorayev, VC at Verve Ventures

loretta@thenextsequence.vc (Xavier Mesnier, Perman Jorayev, Loretta TIOIELA) — Wed, 10 Apr 2024 07:00:00 +0000

Verve Ventures is a network and technology-driven venture capital firm headquartered in Switzerland. Founded in 2010, Verve Ventures has grown to more than 45 team members and has become one of the most active venture investors in Europe with over 140 technology and science-driven startups in its portfolio.

TechBio Founders #30: Developing drug pipelines for life extension and age-related disorders with Ivan De Weber, CEO at Cortex Discovery

loretta@thenextsequence.vc (Ivan De Weber, Loretta TIOIELA) — Wed, 20 Mar 2024 13:00:00 +0000

Cortex Discovery’s in silico drug discovery platform is based on its leading-edge AI technology which can predict molecule properties in all therapeutic fields. The accuracy of its predictions has been validated in the lab, and rivals that of experiments.

TechBio Investors#4- Sonal Pai, VC at First Spark Ventures

loretta@thenextsequence.vc (Loretta TIOIELA) — Wed, 13 Mar 2024 08:00:00 +0000

First Spark Ventures is a Deep Tech venture capital fund investing in breakthrough technologies that make the world healthier, safer, and more productive. First Spark Ventures invests in startups that have fundamental technological insights.We look for stellar teams,large accessible markets, and massive sustainable differentiation.

TechBio Ecosystem & Industry Partners #1-Max Dunhill, ISV Director at Oracle Cloud

loretta@thenextsequence.vc (Loretta TIOIELA, Max Dunhill) — Wed, 27 Dec 2023 08:00:00 +0000

Oracle partners with leading independent software vendors (ISVs) that provide complementary application and technology solutions. Oracle program for ISVs offers a wealth of best practices, lessons learned, and results to share that have transformed—and continue to transform— cloud business. It encompasses Oracle experience migrating more than 60 SaaS-based applications to Oracle Cloud Infrastructure (OCI). These applications support core enterprise functions across eight industry verticals and more than 199,000 customers across the globe.

TechBio Founders #29: Giving you back better insights on your research data through bioinformatic data mining using natural language without hallucinations and knowledge graph with Christopher LI, CEO at BioBox Analytics

loretta@thenextsequence.vc (Christopher Li, Loretta TIOIELA) — Wed, 13 Dec 2023 08:00:00 +0000

BioBox is a software company developing a hybrid Knowledge Graph and LLM system to create a new way for scientists to converse with data, without hallucinations. Fast moving teams in biotech are deploying the BioBox platform to hit R&D milestones in target identification and validation up to 5x faster.

TechBio Investors#3- James Bennett , VC at Earlybird Venture Capital

loretta@thenextsequence.vc (James Bennett, Loretta TIOIELA) — Wed, 6 Dec 2023 08:00:00 +0000

Earlybird Venture Capital focuses on European technology companies. Founded in 1997, Earlybird identifies and backs exceptional early-stage companies on a pan-European basis and supports them through their growth and development phases – providing financial resources, strategic support, and access to an international network & capital markets. With EUR 2 billion under management across all fund streams, 9 IPOs, and 31 trade sales, Earlybird is one of Europe’s most established and active venture capital firms.

TechBio Founders #28: Improving and saving lives by producing high quality human tissue organoids in earth low orbit and space with Raphael Roettgen , CEO at Prometheus Life Technologies

loretta@thenextsequence.vc (Raphael Roettgen, Loretta TIOIELA) — Wed, 29 Nov 2023 08:00:00 +0000

Prometheus Life Technologies is a space biology company out of the University of Zurich, specialized in producing organoids in microgravity. Our team is among the world’s most foremost experts in gravitational biology, and has already successfully flown two missions to the International Space Station to grow human tissue organoids, but we are just getting started on our journey to provide health from space for Earth, and to take biotech to new heights.

TechBio Founders #27: Re-imagining therapeutics within the timeframe of weeks and not years through AI-based design and a high-throughput drug discovery of mini proteins with Chris BAHL, CSO at AI Proteins

loretta@thenextsequence.vc (Chris BAHL, Loretta TIOIELA) — Wed, 22 Nov 2023 08:00:00 +0000

AI Proteins is a biotech company on a mission to re-imagine protein therapeutics with a novel approach for designing entirely new proteins. Using AI-based design and a high-throughput drug discovery platform, AI Proteins creates de novo proteins optimized for specific therapeutic applications. The AI Proteins platform enables the development of inexpensive, durable, highly specific proteins that have the potential for oral delivery. Additionally, the AI Proteins platform can dramatically accelerate the development of lead therapeutic candidates ready for IND enabling studies.

TechBio Venture Associate Insights #2-Neuroscience-Sofia Syntaka

loretta@thenextsequence.vc (Sofia Syntaka, Loretta TIOIELA) — Fri, 17 Nov 2023 16:23:45 +0000

Finishing her PhD in Advanced Therapies and Regenerative Medecine at King's College in UK right now, Sofia is on a mission to support visionaries and companies that develop disruptive solutions for humanity's most pressing challenges, from solving disease to sustainable longevity and environmental preservation. Artificial intelligence and synthetic biology are rapidly evolving, and the impact is tangible in all of our lives. This very intersection is where she believes we will find groundbreaking solutions for neuroscience, novel therapeutics, longevity and beyond. Venture Associate in charge of the Neuroscience vertical at Next Sequence, she is working with founders that share that vision and are poised to reshape these frontiers.

TechBio Founders #26: Developing resilient and autonomous supply chains for research and diagnostics with Jenny Molloy, CEO at Beneficial Bio

loretta@thenextsequence.vc (Jenny Molloy, Loretta TIOIELA) — Wed, 8 Nov 2023 12:00:00 +0000

Beneficial Bio is a network of social enterprises run by biologists which aims to change the status quo for access to biological tools from scarcity to abundance, accelerating research, innovation and education for the bioeconomy. Beneficial Bio’s short term impact is accelerating and scaling local research. Our long term impact is increasing the agency of more people to shape biotechnology, particularly solving local problems without reliance on foreign priorities and developing resilient and autonomous supply chains for research and diagnostics.

TechBio Founders #25: Harnessing evolution to overcome treatment-resistant cancer with Nicholas Goldner, CEO at ResistanceBio

loretta@thenextsequence.vc (Nicholas Goldner, Loretta TIOIELA) — Wed, 1 Nov 2023 12:00:00 +0000

Helping patients fight treatment-resistant cancer. resistanceBio can discover and overcome clinical treatment resistance pre-clinically.

TechBio Founders #24: Using AI and multi-omics to predict the efficacy of immunotherapies with Vadim Nazarov, CEO at ImmunoMind

loretta@thenextsequence.vc (Vadim Nazarov, Loretta TIOIELA) — Wed, 25 Oct 2023 15:53:09 +0000

ImmunoMind is a UC Berkeley SkyDeck alumnus company. ImmunoMind helps biotech companies understand crucial drug-human interactions, and transform the biodata chaos into more effective immunotherapies.

TechBio Venture Associate Insights #1-Food & Agriculture-Alexandre MOREL

loretta@thenextsequence.vc (Alexandre Morel, Loretta TIOIELA) — Tue, 17 Oct 2023 07:00:00 +0000

After earning his Ph.D. in Biomaterials & Bioengineering from ETH Zurich, Alexandre played a pivotal role in establishing Switzerland's first cultivated meat production line, leading the development of innovative bioreactor designs, bioprocessing techniques, and bio-based materials for cultivating stem cells, muscle, and fat tissues.

Currently, Alexandre is actively involved with Next Sequence as a Venture Associate, where he supports TechBio startups in the Food & Agriculture sector.

TechBio Founders #23: Delivering sustainable biomanufacturing with AI-driven microorganism strain optimization with Rachel SHAW, CEO at Eden Bio

loretta@thenextsequence.vc (Rachel SHAW, Loretta TIOIELA) — Fri, 8 Sep 2023 16:15:31 +0000

Eden Bio uses machine learning to improve protein yield, saving companies time and money, and helping them get their proteins to market faster.

TechBio Founders #22: Empowering our digital native world and its digital data exponential growth by ushering in the era of DNA data storage with Erfane ARWANI, CEO Biomemory

loretta@thenextsequence.vc (Erfane Arwani, Loretta TIOIELA) — Wed, 12 Jul 2023 06:00:00 +0000

Biomemory creates DNA Drives for large corporates and administrations. We organize and store data on biocompatible DNA molecules.

TechBio Founders #21: Answering to today's food production problems by harnessing the power of the marine microbiome with Natalija Stepurko and Federica Pesce, CEO & COO at Bravely Cultured

loretta@thenextsequence.vc (Natalija Stepurko, Federica Pesce, Loretta TIOIELA) — Fri, 7 Jul 2023 11:00:00 +0000

At BravelyCultured we are redesigning precision fermentation in order to optimise it for sustainable food production. We take inspiration (as well as microorganisms, seawater and seaweed!) from the ocean to produce animal-free animal proteins in an economically viable way and at scale.

TechBio Founders #20: Regenerating the biodiversity that underpins our food systems by integrating agricultural and biodiversity data across suppliers monitoring through remote sensing and AI with Marianna Herold, CEO NatureBound

loretta@thenextsequence.vc (Marianna Herold, Loretta TIOIELA) — Fri, 16 Jun 2023 07:00:00 +0000

NatureBound is on a mission to regenerate the biodiversity that underpins our food systems.

Combining the latest technology in remote sensing and AI with an open ecosystem of monitoring providers, our ML models leverage scalable biodiversity monitoring to predict agricultural outcomes. Integrating agricultural and biodiversity data across monitoring suppliers into our platform enables a swifter and more profitable transition to sustainable agriculture.

Making siloed biodiversity a thing of the past, NatureBound is building the first Biodiversity Observability Platform.

TechBio Founders #19: Replacing harmful petrochemicals and reinventing the basic materials we use every day through decentralized and scalable algae biomanufacturing with Elliot Roth, CEO Spira Inc.

loretta@thenextsequence.vc (Elliot Roth, Loretta TIOIELA) — Wed, 31 May 2023 07:00:00 +0000

Spira creates carbon negative materials from genetically engineered algae grown by a global network of farming partners to produce ingredients for food, cosmetic and textile companies.

TechBio Founders #18: Fast forwarding the biorevolution in therapeutics modalities by bringing the best cost/performance ratio for generating ultra-high resolution, ultra-high throughput data with Swamy Vijayan, CEO Zafrens

loretta@thenextsequence.vc (Swamy Vijayan, Loretta TIOIELA) — Wed, 24 May 2023 07:00:00 +0000

Zafrens exists at the confluence of engineering, biology, chemistry and informatics to study cells as comprehensively as possible. We map the molecular states of millions of cells at a time to their individual functional manifestations. In doing so we begin to understand the regulatory layers of the cell (how molecular state is converted to function), which, so far has remained challenging to study.

TechBio Investors#2-Alex Felman, General Partner at Felman Family Office

loretta@thenextsequence.vc (Alex Felman, Loretta TIOIELA) — Wed, 17 May 2023 07:00:00 +0000

Alex Felman is a veteran of the family office community for almost a decade; working as managing director with his own family office, Felman Family Office, on the ground with local families in Brazil, China, Denmark and South Korea and remotely with other family offices around the globe.

He uses his expertise in Molecular Toxicology andBio-entrepreneurship(B.A from University of California -Berkeley, MBA from Copenhagen Business School) to advise them in biotechnology, healthcare, and other futuristic tech industries with the goal of maintaining long-term wealth through innovation.

He is personally involved with a number of early-stage companies having previously worked as a general partner of Venture Labs, an early stage venture capital/ incubator fund as well as a mentor, advisor, serial entrepreneur and director of numerous startups. Alex is an expert in helping companies with business plan creation, product development, operations, successful market launches, and fundraising.

TechBio Founders #17: Powering precision medicine in oncology, immunology, infectious diseases, and drug development through single-cell multiomics sequencing technologies with Nan Fang, CEO Singleron Biotechnologies

loretta@thenextsequence.vc (Nan Fang, Loretta TIOIELA) — Wed, 10 May 2023 07:00:00 +0000

Singleron Biotechnologies is an innovative molecular diagnostic company dedicated to applying groundbreaking high-throughput single cell analyses to clinical research, diagnostics and drug development. 500+ single-cell sequencing experts around the world are working together to translate advanced and proprietary multi-omics single-cell technologies into products that can be easily deployed in any lab and provide improved research results faster than ever before.

TechBio Founders #16: Accelerating drug discovery with fully automated robotic experiment execution and digital data capture with Martin-Immanuel Bittner, CEO Arctoris

loretta@thenextsequence.vc (Martin-Immanuel Bittner, Loretta TIOIELA) — Fri, 5 May 2023 06:00:00 +0000

Arctoris is a tech-enabled drug discovery company headquartered in Oxford and Boston. Arctoris combines its unique automation platform, Ulysses, with advanced computational approaches and a world-class team of seasoned drug hunters to guide and rapidly progress its wholly owned and partnered drug discovery programs in oncology and neurology.

TechBio Founders #15: Growing the regenerative materials economy with Elizabeth CORBIN, CEO Materiom

loretta@thenextsequence.vc (Liz Corbin, Loretta TIOIELA) — Wed, 26 Apr 2023 16:04:59 +0000

With open data and AI, Materiom empowers scientists, material developers, and brands to accelerate R&D and drive massive market entry. Materiom platform gathers the world of regenerative material solutions to optimize and match them to real-world needs.

TechBio Founders #14 : Transforming human antibodies into drugs with Wyatt McDonnell, CEO Infinimmune

loretta@thenextsequence.vc (Wyatt McDonnell, Loretta TIOIELA) — Wed, 19 Apr 2023 07:00:00 +0000

Infinimmune’s founding team are tool builders who design from first principles and have broad expertise across immunology, single cell technologies, protein engineering, computational biology, and genome assembly.Transforming human antibodies into drugs.

TechBio Founders #13: Making everyday essentials sustainable through computer-powered precision fermentation with Ben Williams, CTO Sun Bear Bioworks

loretta@thenextsequence.vc (Ben Williams, Loretta TIOIELA) — Wed, 12 Apr 2023 07:00:00 +0000

We believe that everyone should be able to make easy choices they know are sustainable and healthy.

We are reimagining farming by blending the natural process of fermentation with modern science and technology, in order to make everyday essentials.

We just happen to make a great alternative to palm oil.

TechBio Investors#1-Cecilia Manduca, VC at Talis Capital

loretta@thenextsequence.vc (Cecilia Manduca, Loretta TIOIELA) — Wed, 5 Apr 2023 07:00:00 +0000

Investing on behalf of a group of ultra successful entrepreneurs, Talis Capital backs visionary founders at Seed and Serie A. Talis invests with high conviction at Seed & Series A across Europe and US and help founders build category defining companies such as Darktrace, Onfido, Ynsect, Pricefx, Seqera Labs, PortalOne, Howl

TechBio Regulations & Policies #1: What's next for the bioeconomy in Africa with Ian Peter Busuulwa, Coordinator at Bieconomy Coalition of Africa

loretta@thenextsequence.vc (Ian Peter Busuulwa, Loretta TIOIELA) — Wed, 29 Mar 2023 07:00:00 +0000

Discussing about Policy for the Bioeconomy in Africa including:

-World Organisation for Animal Health: A global authority on animal health: we work to ensure the health of animals & their environments across the world, recognising that animal health impacts everyone’s health & that the safety of our future depends on it.

- Bioeconomy Coalition of Africa: A platform of stakeholders working together to grow the bioeconomy in Africa. The platform is hosted by Science Foundation for Livelihoods and Development.

TechBio Founders #12: Scaling the bioeconomy supply chain by building bioprocesses programming cells to express any proteins the way you need it with Mona Oliveira, CEO BioLinker

loretta@thenextsequence.vc (Loretta TIOIELA, Mona Oliveira) — Wed, 15 Mar 2023 09:46:49 +0000

BioLinker is a biotechnology company that using synthetic biology to provide kits for the synthesis of cell-free recombinant proteins, in addition to solutions and services for the production and purification of recombinant proteins in several systems.

TechBio Founders #11: Reeducating the body through next-generation nutrients engineereed with RNA with Silvana Spinelli, CEO Kresko RNAtech

loretta@thenextsequence.vc (Loretta TIOIELA, Silvana Spinelli) — Wed, 22 Feb 2023 08:00:00 +0000

At Kresko we believe that the time has come to apply RNA technologies to address today´s health challenges by improving our nutrition. We want people to think of food not only as a source of nutrients but also as essential information for adaptation and self-development.

TechBio Founders #10: Manufacturing a more sustainable future by scaling alternative proteins down stream processing with Zoe Yu TUNG LAW, CEO New Wave Biotech

loretta@thenextsequence.vc (Zoe Yu Tung Law, Loretta TIOIELA) — Wed, 15 Feb 2023 16:00:00 +0000

New Wave Biotech is developing computational modelling to help precision fermentation alt protein companies optimise their downstream processing, so they can de-risk their ventures, speed up R&D and reduce costs. By doing this, they aim to accelerate the sustainable transformation of food production.

TechBio Founders #9: Helping biotech companies digitise their microbial R&D by building the next generation robotics and lab automation with Carl-Emil Grøn, CEO Reshape Biotech

loretta@thenextsequence.vc (Carl-Emil Grøn, Loretta TIOIELA) — Wed, 8 Feb 2023 08:00:00 +0000

Reshape is building the next generation of biotech laboratories. We automate everything from filling plates to analyzing images to allow researchers and engineers to spend their time more efficiently

TechBio Founders #8: Feeding 10 Billions people on our planet through Ocean Agriculture with Luke Young & Rory Hornby, CEO & CSO at Alora

loretta@thenextsequence.vc (Luke Young, Rory Hornby, Loretta TIOIELA) — Wed, 1 Feb 2023 08:00:00 +0000

Alora is the next frontier ocean agriculture company building a platform to produce enough food for 10 billion people while using no freshwater, no chemical fertilisers or pesticides and very little land.

TechBio Founders #7: Solving the plastic waste crisis by closing the recycling loop using enzymatic degradation with Andrii Shekhirev, CEO Enzymity

loretta@thenextsequence.vc (Andrii Shekhirev, Loretta TIOIELA) — Wed, 25 Jan 2023 08:00:00 +0000

Enzymity is a bioplatform developing a method for breaking down polymers such as plastics and resins into monomers with the help of synthetic enzymes. The enzymes are tailored for specific types of material (e.g. PET or synthetic rubber) and are produced by genetically modified microorganisms. The monomers which result from the process can be used to create new virgin polymers, thus reducing the need for fossil fuel derived plastics/resins. This cycle can be repeated many times and does not deteriorate the quality of the material, as opposed to the currently prevalent mechanical recycling.

TechBio Founders #6: Reinventing the protein design and chemistry workflow through MLOPs with Tyler Shimko, CEO Trident Bioscience

loretta@thenextsequence.vc (Tyler Shimko, Loretta TIOIELA) — Wed, 18 Jan 2023 08:00:00 +0000

Trident Bioscience builds tools to expedite the discovery and optimization of useful proteins. By combining technologies, they're closing the design-build-test loop of protein optimization and cutting the total cycle time to help bring game changing proteins to market faster than ever before.

TechBio Founders #5: Empowering digital pathology and medical images based research by generating synthetic images with Fabian Schvartzman, CEO Sentient Med

loretta@thenextsequence.vc (Fabian Schvartzman, Loretta TIOIELA) — Wed, 11 Jan 2023 14:19:21 +0000

Sentient Med is a digital healthcare company focused on improving digital pathology and medical modalities through cutting-edge machine learning to create tailor-made synthetic image datasets for the purpose of overcoming bias and other data limitations and deliver valuable images that are free of any privacy concern.

TechBio Founders #4: Targeting the core drivers of age-related diseases with Daniel Oliver, CEO Rejuvenate Bio

loretta@thenextsequence.vc (Daniel Oliver, Loretta TIOIELA) — Wed, 4 Jan 2023 08:00:00 +0000

Rejuvenate Bio is developing novel therapies to treat aging and age-related diseases through innovative targeted gene therapies and developing treatments to reverse aging and address multiple age-related diseases.

TechBio Founders #3: Treating mental illness: The Power of Psychedelics with Sam Banister, CSO Psylo

loretta@thenextsequence.vc (Loretta TIOIELA) — Wed, 28 Dec 2022 08:00:00 +0000

Psylo is a drug development company focused on next generation psychedelics; Their goal is to make broadly accessible medicines as improved treatments to currently available SSRI medications, using psychedelic molecules as the starting point. They are building a pipeline of novel molecules with the ultimate goal of taking leading candidates through to clinical trials.

TechBio Founders #2: Building tomorrow's biopersonna and personalized medicine through the gut microbiome with Ian CHONG, CEO OSBiome

loretta@thenextsequence.vc (Loretta TIOIELA, Ian Chong) — Wed, 14 Dec 2022 08:00:00 +0000

OSbiome is a personalised digital health company that combines gut microbiome technology with AI to provides bespoke (and simple) nutrition and lifestyle recommendations to improve your gut health and overall wellness.

TechBio Founders #1:Designing & delivering proprietary biofactories with Rishita Changede, CEO TeOra

loretta@thenextsequence.vc (Rishita Changede, Loretta TIOIELA) — Wed, 23 Nov 2022 08:00:00 +0000

Teora is a synthetic biology startup utilizing bioinformatics and material science to create vaccines delivered orally. The platform targets the trillion dollar food production industry to increase yield, enhance growth, replace harmful chemicals with natural and sustainable biologics in shrimp, fish, animals, and plants. Based on their understanding of the problem and strong tractions from major farms, they started developing solution aquaculture space ( 280B USD), which incredibly important to feeding a growing and hungry planet, but there are no effective solutions for viral or bacterial disease. For example, White Spot Syndrome virus can kill an entire shrimp farm crop in less than a week - bringing devastating economic losses of over $6B annually. Right now, absolutely no preventive solutions exist.