https://simplecast.com On the Edge of Breakthrough: Voices of Cancer Research Welcome to On the Edge of Breakthrough: Voices of Cancer Research, your gateway to the latest in cancer care innovation. Hosted by Dr. Monty Pal, a medical oncologist and researcher at City of Hope, we’ll bring you inside one of the top 5 cancer research and treatment institutions in the U.S., where innovation and hope go hand-in-hand. Join Dr. Pal as he sits down with some of the world’s leading cancer experts as they explore some of the most pressing challenges and promising innovations in oncology today. Whether you're a seasoned healthcare professional, a curious researcher, or simply someone passionate about the fight against cancer, this podcast is your front row seat to hear about the discoveries defining the future of cancer care. 2025 City of Hope en Tue, 21 Apr 2026 19:00:00 +0000 Tue, 21 Apr 2026 19:00:12 +0000 https://on-the-edge-of-breakthrough.simplecast.com On the Edge of Breakthrough: Voices of Cancer Research https://image.simplecastcdn.com/images/81e20e2f-faef-4318-bc36-f21c836d32d0/e0750f3b-65f4-4bf0-95cf-2712d05a3a6d/3000x3000/option-20-3.jpg?aid=rss_feed https://on-the-edge-of-breakthrough.simplecast.com episodic Welcome to On the Edge of Breakthrough: Voices of Cancer Research, your gateway to the latest in cancer care innovation. Hosted by Dr. Monty Pal, a medical oncologist and researcher at City of Hope, we’ll bring you inside one of the top 5 cancer research and treatment institutions in the U.S., where innovation and hope go hand-in-hand. Join Dr. Pal as he sits down with some of the world’s leading cancer experts as they explore some of the most pressing challenges and promising innovations in oncology today. Whether you're a seasoned healthcare professional, a curious researcher, or simply someone passionate about the fight against cancer, this podcast is your front row seat to hear about the discoveries defining the future of cancer care. City of Hope false https://feeds.simplecast.com/oXXBlHCA city of hope City of Hope stories@amazemedialabs.com 2483d936-6f00-4a2f-8d35-0a6dd915627c What it Takes to Close the Gap in Pediatric Cancer Care with Leo Wang, M.D., Ph.D. While many childhood leukemias are now highly curable, Dr. Wang explains children with certain aggressive brain tumors still face the same outcomes they did a decade ago. This lag in progress is what drives his work today investigating CAR T‑cell therapy gene therapy in early phase clinical trials.

Throughout the conversation, Dr. Wang returns to the idea that progress in pediatric cancer care depends on collaboration across institutions, bringing together patient care, careful study and shared commitment across the research community. For him, the work centers on honoring the trust families place in the field and steadily moving discoveries from the lab to children who need more options and more time.

]]> Tue, 21 Apr 2026 19:00:00 +0000 stories@amazemedialabs.com (Prue Buxton, Dr. Monty Pal, Dr. Leo Wang, Michael Harkins, Matt Hamil) https://on-the-edge-of-breakthrough.simplecast.com/episodes/what-it-takes-to-close-the-gap-in-pediatric-cancer-care-with-leo-wang-md-phd-O084X6tp While many childhood leukemias are now highly curable, Dr. Wang explains children with certain aggressive brain tumors still face the same outcomes they did a decade ago. This lag in progress is what drives his work today investigating CAR T‑cell therapy gene therapy in early phase clinical trials.

Throughout the conversation, Dr. Wang returns to the idea that progress in pediatric cancer care depends on collaboration across institutions, bringing together patient care, careful study and shared commitment across the research community. For him, the work centers on honoring the trust families place in the field and steadily moving discoveries from the lab to children who need more options and more time.

]]> What it Takes to Close the Gap in Pediatric Cancer Care with Leo Wang, M.D., Ph.D. Prue Buxton, Dr. Monty Pal, Dr. Leo Wang, Michael Harkins, Matt Hamil 00:46:13 In this episode, Leo Wang, M.D., Ph.D., pediatric oncologist, Clinical Director of the Gene Therapy Program and Director of the City of Hope Alpha Clinic, discusses the realities of caring for children with cancers that still have few effective treatments. He reflects on what it takes to begin changing those realities for patients and families. In this episode, Leo Wang, M.D., Ph.D., pediatric oncologist, Clinical Director of the Gene Therapy Program and Director of the City of Hope Alpha Clinic, discusses the realities of caring for children with cancers that still have few effective treatments. He reflects on what it takes to begin changing those realities for patients and families. brain tumor, gene therapy, childhood cancer, what is cancer, cancer center, cancer diagnosis, pediatric oncology, cancer treatment, cancer doctor, city of hope national medical center, cancer research, brain cancer, city of hope, cell therapy, car t cell therapy, car-t false full 6 4 0530deaa-f2cc-4780-824a-773b676a551e Reengineering CAR T for Solid Tumors: What Glioblastoma Has Taught Us with Christine Brown, Ph.D. In this episode of On the Edge of Breakthrough: Voices of Cancer Research, Christine Brown, Ph.D., Deputy Director of the T‑Cell Research Laboratory at City of Hope, joins Monty Pal, M.D., F.A.S.C.O., to discuss how years of research in glioblastoma, one of the most aggressive and difficult brain cancers, are helping scientists rethink how CAR T‑cell therapy could effectively treat solid tumors.  

Dr. Brown shares lessons learned from treating patients with few options, including how tumors change over time and how the brain’s environment can limit immune‑based treatments. 

The conversation explores Brown’s early leadership in delivering CAR T cells directly into the brain, rather than through the bloodstream. The episode delves into her key clinical experiences that revealed both the potential of CAR T‑cell therapy and the challenges of making clinical responses last. 

Dr. Brown explains new up and coming approaches designed to improve durability and effectiveness, how these advances could extend beyond cancer to autoimmune diseases. She returns to a simple point: studying how real patients respond—what works, what doesn’t, and why—will shape every next step in her research. 

]]> Tue, 7 Apr 2026 04:00:00 +0000 stories@amazemedialabs.com (Dr. Monty Pal, Dr. Christine Brown, Prue Buxton, Michael Harkins, Matt Hamil, Justin Delos Reyes) https://on-the-edge-of-breakthrough.simplecast.com/episodes/reengineering-car-t-for-solid-tumors-what-glioblastoma-has-taught-us-with-christine-brown-phd-XFVSeZbt In this episode of On the Edge of Breakthrough: Voices of Cancer Research, Christine Brown, Ph.D., Deputy Director of the T‑Cell Research Laboratory at City of Hope, joins Monty Pal, M.D., F.A.S.C.O., to discuss how years of research in glioblastoma, one of the most aggressive and difficult brain cancers, are helping scientists rethink how CAR T‑cell therapy could effectively treat solid tumors.  

Dr. Brown shares lessons learned from treating patients with few options, including how tumors change over time and how the brain’s environment can limit immune‑based treatments. 

The conversation explores Brown’s early leadership in delivering CAR T cells directly into the brain, rather than through the bloodstream. The episode delves into her key clinical experiences that revealed both the potential of CAR T‑cell therapy and the challenges of making clinical responses last. 

Dr. Brown explains new up and coming approaches designed to improve durability and effectiveness, how these advances could extend beyond cancer to autoimmune diseases. She returns to a simple point: studying how real patients respond—what works, what doesn’t, and why—will shape every next step in her research. 

]]> Reengineering CAR T for Solid Tumors: What Glioblastoma Has Taught Us with Christine Brown, Ph.D. Dr. Monty Pal, Dr. Christine Brown, Prue Buxton, Michael Harkins, Matt Hamil, Justin Delos Reyes 00:42:31 In this episode of On the Edge of Breakthrough: Voices of Cancer Research, Christine Brown, Ph.D., Deputy Director of the T Cell Research Laboratory at City of Hope, joins Monty Pal, M.D., F.A.S.C.O., to discuss how years of research in glioblastoma, one of the most aggressive and difficult brain cancers, are helping scientists rethink how CAR T cell therapy could effectively treat solid tumors. In this episode of On the Edge of Breakthrough: Voices of Cancer Research, Christine Brown, Ph.D., Deputy Director of the T Cell Research Laboratory at City of Hope, joins Monty Pal, M.D., F.A.S.C.O., to discuss how years of research in glioblastoma, one of the most aggressive and difficult brain cancers, are helping scientists rethink how CAR T cell therapy could effectively treat solid tumors. brain tumor, clinical trials, immunotherapy, cancer, t-cells, glioblastoma, oncology research, city of hope national medical center, cancer research, brain cancer, car-tregs, city of hope, cell therapy, car t cell therapy, car-t false full 5 4 c9895cbc-f868-4ed4-9353-34d053a32906 The Long Game of Cancer Genomics: John Carpten, Ph.D., on Building Precision Oncology that Reaches Patients Dr. Carpten traces the less-linear path that brought him to the forefront of the field, from his early interests in biology and sports to a pivotal moment in college, when a red-covered Life magazine helped crystallize his career trajectory toward genomics.

This curiosity led Carpten to his work on the Human Genome Project, where he significantly contributed to mapping the human genome years before a reference sequence existed. He later helped build translational genomics programs from the ground up, including as a founding member of the Translational Genomics Research Institute (TGen), turning limited resources into platforms for discovery and application.

The episode tackles what makes breakthroughs durable: building programs, technologies and teams that are inclusive, scalable and designed for clinical impact. Carpten shares how City of Hope is integrating genomics, spatial biology and emerging approaches such as AI to accelerate translation—with an emphasis on rigor, implementation and access.

]]> Tue, 24 Mar 2026 04:00:00 +0000 stories@amazemedialabs.com (Prue Buxton, Dr. Monty Pal, Dr. John Carpten, Matt Hamil, Michael Harkins, Justin Delos Reyes) https://on-the-edge-of-breakthrough.simplecast.com/episodes/the-long-game-of-cancer-genomics-john-carpten-phd-on-building-precision-oncology-that-reaches-patients-oqB_Ac7D Dr. Carpten traces the less-linear path that brought him to the forefront of the field, from his early interests in biology and sports to a pivotal moment in college, when a red-covered Life magazine helped crystallize his career trajectory toward genomics.

This curiosity led Carpten to his work on the Human Genome Project, where he significantly contributed to mapping the human genome years before a reference sequence existed. He later helped build translational genomics programs from the ground up, including as a founding member of the Translational Genomics Research Institute (TGen), turning limited resources into platforms for discovery and application.

The episode tackles what makes breakthroughs durable: building programs, technologies and teams that are inclusive, scalable and designed for clinical impact. Carpten shares how City of Hope is integrating genomics, spatial biology and emerging approaches such as AI to accelerate translation—with an emphasis on rigor, implementation and access.

]]> The Long Game of Cancer Genomics: John Carpten, Ph.D., on Building Precision Oncology that Reaches Patients Prue Buxton, Dr. Monty Pal, Dr. John Carpten, Matt Hamil, Michael Harkins, Justin Delos Reyes 00:56:15 In this episode of On the Edge of Breakthrough: Voices of Cancer Research, John Carpten, Ph.D., Chief Scientific Officer at City of Hope, discusses the evolution of cancer genomics—how early genome mapping enabled today’s targeted approaches and what infrastructure and equity considerations will determine what comes next. In this episode of On the Edge of Breakthrough: Voices of Cancer Research, John Carpten, Ph.D., Chief Scientific Officer at City of Hope, discusses the evolution of cancer genomics—how early genome mapping enabled today’s targeted approaches and what infrastructure and equity considerations will determine what comes next. cancer, ai, human genome project, prostate cancer, precision oncology, oncology research, precision medicine, city of hope national medical center, oncologist, cancer research, science, city of hope, genomics false full 4 4 e14b81be-7e9b-4f67-b5b4-23ed92ac7e97 How Engineered Antibodies and Next Generation Imaging Tools are Reshaping Cancer Care with Anna Wu, Ph.D. Dr. Wu shares insights on her team’s development of engineered antibodies and fast‑clearing mini‑body fragments. These fragments can initially be used for PET imaging and then later paired with therapeutic radioisotopes to precisely target tumors, which help clinicians see where the treatment is going and how well it may work. 

She also talks about two exciting initiatives at City of Hope: CEA‑directed agents (targeted cancer therapies) that are being used in clinical imaging and therapy; and PSCA‑targeted radiopharmaceuticals, which are entering first‑in‑human studies for pancreatic and prostate cancers. These new approaches use imaging to zero in on the tumor target, confirm safety, then deliver the radiation therapy directly to cancer cells. 

]]> Tue, 10 Mar 2026 04:00:00 +0000 stories@amazemedialabs.com (Dr. Monty Pal, Dr. Anna Wu, Prue Buxton, Matt Hamil, Michael Harkins, Justin Delos Reyes) https://on-the-edge-of-breakthrough.simplecast.com/episodes/how-engineered-antibodies-and-next-generation-imaging-tools-are-reshaping-cancer-care-with-anna-wu-phd-yi8KiHlY Dr. Wu shares insights on her team’s development of engineered antibodies and fast‑clearing mini‑body fragments. These fragments can initially be used for PET imaging and then later paired with therapeutic radioisotopes to precisely target tumors, which help clinicians see where the treatment is going and how well it may work. 

She also talks about two exciting initiatives at City of Hope: CEA‑directed agents (targeted cancer therapies) that are being used in clinical imaging and therapy; and PSCA‑targeted radiopharmaceuticals, which are entering first‑in‑human studies for pancreatic and prostate cancers. These new approaches use imaging to zero in on the tumor target, confirm safety, then deliver the radiation therapy directly to cancer cells. 

]]> How Engineered Antibodies and Next Generation Imaging Tools are Reshaping Cancer Care with Anna Wu, Ph.D. Dr. Monty Pal, Dr. Anna Wu, Prue Buxton, Matt Hamil, Michael Harkins, Justin Delos Reyes 00:41:30 In this episode of On the Edge of Breakthrough: Voices of Cancer Research, Anna Wu, Ph.D., Chair of the Department of Immunology and Theranostics at City of Hope, joins host Monty Pal, M.D., for an engaging discussion on how innovations in antibody engineering and imaging are improving clinicians’ ability to visualize tumors and guide more effective treatment strategies. In this episode of On the Edge of Breakthrough: Voices of Cancer Research, Anna Wu, Ph.D., Chair of the Department of Immunology and Theranostics at City of Hope, joins host Monty Pal, M.D., for an engaging discussion on how innovations in antibody engineering and imaging are improving clinicians’ ability to visualize tumors and guide more effective treatment strategies. tumors, clinical trials, cancer, antibodies, what is cancer, pancreatic cancer, prostate cancer, oncology, oncology research, radiopharmaceuticals, city of hope national medical center, theranostics, cancer research, city of hope false full 3 4 5c7bd3b3-f753-4609-8f18-e0940e2693b7 Unlocking the Future of Cancer Care: Precision Medicine, AI and the Patient Voice with Dr. Stacy Gray In this episode of On the Edge of Breakthrough: Voices of Cancer Research, Stacy Gray, M.D., A.M., Director of Clinical and Scientific Strategy and Vice President of System Strategy at City of Hope, joins Monty Pal, M.D., F.A.S.C.O. in an engaging discussion of how precision medicine and AI are transforming cancer care and why listening to patients is the key to it all. 

Dr. Gray highlights City of Hope’s leadership in precision medicine, from expanded germline testing and the INSPIRE program to emerging early‑detection studies using whole‑body MRI and liquid biopsy. The episode dissects how system‑wide integration and new technologies can expand access to expert opinions, match patients to clinical trials and ensure high‑quality cancer care, regardless of a patient’s geographic location.

Oncologists sometimes worry that sharing genomic results without concrete recommendations may increase patients’ anxiety. But as Dr. Gray notes, research shows that what patients want most is actionable information that helps them understand what comes next. Her work has helped catalyze innovations such as molecular tumor boards and large‑scale genomic programs that make testing more accessible and clinically meaningful.

 

]]> Tue, 24 Feb 2026 05:00:00 +0000 stories@amazemedialabs.com (Dr. Monty Pal, Dr. Stacy Gray, Prue Buxton, Michael Harkins, Matt Hamil, Justin Delos Reyes) https://on-the-edge-of-breakthrough.simplecast.com/episodes/unlocking-the-future-of-cancer-care-precision-medicine-ai-and-the-patient-voice-with-dr-stacy-gray-dqAp_Shg In this episode of On the Edge of Breakthrough: Voices of Cancer Research, Stacy Gray, M.D., A.M., Director of Clinical and Scientific Strategy and Vice President of System Strategy at City of Hope, joins Monty Pal, M.D., F.A.S.C.O. in an engaging discussion of how precision medicine and AI are transforming cancer care and why listening to patients is the key to it all. 

Dr. Gray highlights City of Hope’s leadership in precision medicine, from expanded germline testing and the INSPIRE program to emerging early‑detection studies using whole‑body MRI and liquid biopsy. The episode dissects how system‑wide integration and new technologies can expand access to expert opinions, match patients to clinical trials and ensure high‑quality cancer care, regardless of a patient’s geographic location.

Oncologists sometimes worry that sharing genomic results without concrete recommendations may increase patients’ anxiety. But as Dr. Gray notes, research shows that what patients want most is actionable information that helps them understand what comes next. Her work has helped catalyze innovations such as molecular tumor boards and large‑scale genomic programs that make testing more accessible and clinically meaningful.

 

]]> Unlocking the Future of Cancer Care: Precision Medicine, AI and the Patient Voice with Dr. Stacy Gray Dr. Monty Pal, Dr. Stacy Gray, Prue Buxton, Michael Harkins, Matt Hamil, Justin Delos Reyes 00:43:44 In this episode of On the Edge of Breakthrough: Voices of Cancer Research, Stacy Gray, M.D., A.M., Director of Clinical and Scientific Strategy and Vice President of System Strategy at City of Hope, joins Monty Pal, M.D., F.A.S.C.O. in an engaging discussion of how precision medicine and AI are transforming cancer care and why listening to patients is the key to it all. In this episode of On the Edge of Breakthrough: Voices of Cancer Research, Stacy Gray, M.D., A.M., Director of Clinical and Scientific Strategy and Vice President of System Strategy at City of Hope, joins Monty Pal, M.D., F.A.S.C.O. in an engaging discussion of how precision medicine and AI are transforming cancer care and why listening to patients is the key to it all. translational research, what is cancer, ai, cancer treatment, oncology, oncology research, precision medicine, city of hope national medical center, cancer research, city of hope, genomics false full 2 4 078b6948-b563-42f6-9c9a-c952a1f2dfe2 How Team Science Fuels Cancer Breakthroughs: A Conversation with Dr. Marcel van den Brink In the season 4 premiere of On the Edge of Breakthrough: Voices of Cancer Research, Monty Pal, M.D., F.A.S.C.O., welcomes Marcel van den Brink, M.D., Ph.D., President of City of Hope Los Angeles and City of Hope National Medical Center, Chief Physician Executive and the Deana and Steve Campbell Physician Executive Distinguished Chair.

From mentorship and team science to the intersection of clinical care, innovation and personal resilience, this episode offers a candid look at the experiences and values driving one of cancer research’s most impactful leaders.

Together, they trace Dr. van den Brink’s remarkable journey from his early medical training in Holland—including formative mentorship under pioneering immunologists—to pivotal experiences that brought him to the U.S. and shaped his career as a physician-scientist. Van den Brink reflects on the challenges of navigating academic systems, the grit required during demanding residency years and the turning points that led him to leadership roles at premier cancer centers.

The conversation highlights Dr. van den Brink’s groundbreaking scientific contributions, including discoveries that have advanced understanding of T cell biology, the thymus, immune recovery and the microbiome’s role in transplant outcomes. He discusses his philosophy of fostering open, collaborative research environments and the importance of rethinking traditional academic models to empower the next generation of scientists.

 

]]> Tue, 10 Feb 2026 05:00:00 +0000 stories@amazemedialabs.com (Michael Harkins, Matt Hamil, Dr. Monty Pal, Justin Delos Reyes, Dr. van den Brink, Prue Buxton) https://on-the-edge-of-breakthrough.simplecast.com/episodes/how-team-science-fuels-cancer-breakthroughs-a-conversation-with-dr-marcel-van-den-brink-tFEGHDaR In the season 4 premiere of On the Edge of Breakthrough: Voices of Cancer Research, Monty Pal, M.D., F.A.S.C.O., welcomes Marcel van den Brink, M.D., Ph.D., President of City of Hope Los Angeles and City of Hope National Medical Center, Chief Physician Executive and the Deana and Steve Campbell Physician Executive Distinguished Chair.

From mentorship and team science to the intersection of clinical care, innovation and personal resilience, this episode offers a candid look at the experiences and values driving one of cancer research’s most impactful leaders.

Together, they trace Dr. van den Brink’s remarkable journey from his early medical training in Holland—including formative mentorship under pioneering immunologists—to pivotal experiences that brought him to the U.S. and shaped his career as a physician-scientist. Van den Brink reflects on the challenges of navigating academic systems, the grit required during demanding residency years and the turning points that led him to leadership roles at premier cancer centers.

The conversation highlights Dr. van den Brink’s groundbreaking scientific contributions, including discoveries that have advanced understanding of T cell biology, the thymus, immune recovery and the microbiome’s role in transplant outcomes. He discusses his philosophy of fostering open, collaborative research environments and the importance of rethinking traditional academic models to empower the next generation of scientists.

 

]]> How Team Science Fuels Cancer Breakthroughs: A Conversation with Dr. Marcel van den Brink Michael Harkins, Matt Hamil, Dr. Monty Pal, Justin Delos Reyes, Dr. van den Brink, Prue Buxton 00:57:24 In the season 4 premiere of On the Edge of Breakthrough: Voices of Cancer Research, Monty Pal, M.D., F.A.S.C.O., welcomes Marcel van den Brink, M.D., Ph.D., President of City of Hope Los Angeles and City of Hope National Medical Center, Chief Physician Executive and the Deana and Steve Campbell Physician Executive Distinguished Chair. From mentorship and team science to the intersection of clinical care, innovation and personal resilience, this episode offers a candid look at the experiences and values driving one of cancer research’s most impactful leaders. In the season 4 premiere of On the Edge of Breakthrough: Voices of Cancer Research, Monty Pal, M.D., F.A.S.C.O., welcomes Marcel van den Brink, M.D., Ph.D., President of City of Hope Los Angeles and City of Hope National Medical Center, Chief Physician Executive and the Deana and Steve Campbell Physician Executive Distinguished Chair. From mentorship and team science to the intersection of clinical care, innovation and personal resilience, this episode offers a candid look at the experiences and values driving one of cancer research’s most impactful leaders. oncology researcher, immunotherapy, microbiome, what is cancer, cancer center, cancer diagnosis, oncology, oncology research, cancer doctor, city of hope national medical center, t cells, oncologist, mentorship, cancer research, physician-scientist, city of hope, car-t false full 1 4 36dc2b10-9eea-473c-b77a-12c706077737 How Mentorship Sparks Innovation: A Conversation with Dr. Wesley Yip In the season 3 finale episode of On the Edge of Breakthrough: Voices of Cancer Research, Dr. Monty Pal welcomes Wesley Yip, M.D., Assistant Professor, Division of Urology and Urologic Oncology, Department of Surgery at City of Hope.

The duo explores Dr. Yip’s career journey sparked by an early inspiration in his father’s urology practice to the cutting-edge urological oncology and microbiome research he now leads. 

The conversation delves into Dr. Yip’s innovative work investigating the role of the microbiome in kidney cancer, the rigorous protocols required for scientific discovery and the promise of microbiome modulation to improve patient outcomes. He discusses the importance of mentorship, collaboration, and building multidisciplinary teams, as well as the challenges and rewards of balancing clinical practice, research, and family life.

Beyond his scientific achievements, Dr. Yip reflects on the value of asking for help, the power of saying “no” to stay focused on long-term goals, and his commitment to mentoring the next generation of cancer researchers. He shares advice for aspiring surgeon-scientists on embracing collaboration, seeking guidance, and pursuing personalized approaches at the edge of breakthrough.

Follow Us:

Presented by City of Hope: www.CityOfHope.org

]]> Wed, 7 Jan 2026 05:00:00 +0000 stories@amazemedialabs.com (Dr. Wesley Yip, Michael Harkins, Matt Hamil, Justin Delos Reyes, Prue Buxton, Dr. Monty Pal) https://on-the-edge-of-breakthrough.simplecast.com/episodes/how-mentorship-accelerates-innovation-a-conversation-with-dr-wesley-yip-9ssXEMze In the season 3 finale episode of On the Edge of Breakthrough: Voices of Cancer Research, Dr. Monty Pal welcomes Wesley Yip, M.D., Assistant Professor, Division of Urology and Urologic Oncology, Department of Surgery at City of Hope.

The duo explores Dr. Yip’s career journey sparked by an early inspiration in his father’s urology practice to the cutting-edge urological oncology and microbiome research he now leads. 

The conversation delves into Dr. Yip’s innovative work investigating the role of the microbiome in kidney cancer, the rigorous protocols required for scientific discovery and the promise of microbiome modulation to improve patient outcomes. He discusses the importance of mentorship, collaboration, and building multidisciplinary teams, as well as the challenges and rewards of balancing clinical practice, research, and family life.

Beyond his scientific achievements, Dr. Yip reflects on the value of asking for help, the power of saying “no” to stay focused on long-term goals, and his commitment to mentoring the next generation of cancer researchers. He shares advice for aspiring surgeon-scientists on embracing collaboration, seeking guidance, and pursuing personalized approaches at the edge of breakthrough.

Follow Us:

Presented by City of Hope: www.CityOfHope.org

]]> How Mentorship Sparks Innovation: A Conversation with Dr. Wesley Yip Dr. Wesley Yip, Michael Harkins, Matt Hamil, Justin Delos Reyes, Prue Buxton, Dr. Monty Pal 00:35:07 In the season 3 finale episode of On the Edge of Breakthrough: Voices of Cancer Research, Dr. Monty Pal welcomes Wesley Yip, M.D., Assistant Professor, Division of Urology and Urologic Oncology, Department of Surgery at City of Hope. The conversation delves into Dr. Yip’s innovative work investigating the role of the microbiome in kidney cancer, the rigorous protocols required for scientific discovery and the promise of microbiome modulation to improve patient outcomes. He discusses the importance of mentorship, collaboration, and building multidisciplinary teams, as well as the challenges and rewards of balancing clinical practice, research, and family life. In the season 3 finale episode of On the Edge of Breakthrough: Voices of Cancer Research, Dr. Monty Pal welcomes Wesley Yip, M.D., Assistant Professor, Division of Urology and Urologic Oncology, Department of Surgery at City of Hope. The conversation delves into Dr. Yip’s innovative work investigating the role of the microbiome in kidney cancer, the rigorous protocols required for scientific discovery and the promise of microbiome modulation to improve patient outcomes. He discusses the importance of mentorship, collaboration, and building multidisciplinary teams, as well as the challenges and rewards of balancing clinical practice, research, and family life. cancer surgery, microbiome, what is cancer, cancer center, cancer diagnosis, cancer treatment, urology, urologic oncology, oncology research, kidney cancer, mentorship, cancer research, science, city of hope false full 6 3 b9bf2391-2ac1-427d-abd8-23e301928432 Bonus: The Future of Cancer Surgery: Innovations, AI and Remote Robotics This is an audience favorite episode. Dr. Monty Pal sits down with Yuman Fong, M.D., an internationally renowned surgical oncologist and Chair of Surgery at City of Hope, to explore the leading-edge innovations shaping the future of surgical oncology.

Dr. Fong shares his incredible journey from studying medieval literature to being one of the first-ever surgeons to conduct surgery in space. They discuss the evolution of oncolytic viruses, the role of AI in cancer surgery, and how remote robotic surgical procedures are transforming patient care worldwide. Dr. Fong also shares  his insights on balancing an intense surgical career with family life, mentorship, and finding passions outside the operating room.

Don’t miss this fascinating conversation about the future of cancer care, where groundbreaking science meets human connection. Subscribe via the links below to listen now.

Follow Us

Presented by City of Hope: www.CityOfHope.org

]]> Tue, 23 Dec 2025 05:00:00 +0000 stories@amazemedialabs.com (Dr. Yuman Fong, Matt Hamil, Justin Delos Reyes, Dr. Monty Pal, Prue Buxton, Michael Harkins) https://on-the-edge-of-breakthrough.simplecast.com/episodes/bonus-the-future-of-cancer-surgery-innovations-ai-and-remote-robotics-CuWnUu03 This is an audience favorite episode. Dr. Monty Pal sits down with Yuman Fong, M.D., an internationally renowned surgical oncologist and Chair of Surgery at City of Hope, to explore the leading-edge innovations shaping the future of surgical oncology.

Dr. Fong shares his incredible journey from studying medieval literature to being one of the first-ever surgeons to conduct surgery in space. They discuss the evolution of oncolytic viruses, the role of AI in cancer surgery, and how remote robotic surgical procedures are transforming patient care worldwide. Dr. Fong also shares  his insights on balancing an intense surgical career with family life, mentorship, and finding passions outside the operating room.

Don’t miss this fascinating conversation about the future of cancer care, where groundbreaking science meets human connection. Subscribe via the links below to listen now.

Follow Us

Presented by City of Hope: www.CityOfHope.org

]]> Bonus: The Future of Cancer Surgery: Innovations, AI and Remote Robotics Dr. Yuman Fong, Matt Hamil, Justin Delos Reyes, Dr. Monty Pal, Prue Buxton, Michael Harkins 00:32:47 This is an audience favorite episode. Dr. Yuman Fong shares insights on AI, robotics, the future of surgical oncology, plus his groundbreaking work in oncolytic viruses and the importance of mentorship. This is an audience favorite episode. Dr. Yuman Fong shares insights on AI, robotics, the future of surgical oncology, plus his groundbreaking work in oncolytic viruses and the importance of mentorship. cancer surgery, immunotherapy, cancer center, cancer diagnosis, ai, cancer treatment, surgery, robotic surgery, oncology research, cancer research, oncolytic virus, city of hope, surgical oncology, car-t false full 5 3 e0ef0185-ffa3-4dbd-8116-3c2d6e9c06d7 The Quest to Cure: Exploring the Latest Frontiers in Autoimmune Disease Treatment In this episode of On the Edge of Breakthrough: Voices of Cancer Research, Dr. Monty Pal welcomes Dr. Enrique Montero, research professor within the Arthur Riggs Diabetes & Metabolism Research Institute, to discuss his global journey in immunology and the pioneering work underway at City of Hope. Dr. Montero shares how early clinical experiences with lupus inspired his lifelong mission to bridge basic science and clinical application, leading to innovative therapies for cancer and autoimmune diseases. 

The episode dives into the significance of the CD6 molecule on T cells - how its overexpression drives inflammation in conditions like type 1 diabetes and graft-versus-host disease (GVHD). The duo discusses the development of targeted monoclonal antibodies and a groundbreaking approach using genetically modified regulatory T cells—CAR Tregs—to modulate immune responses, aiming not just to control disease but to regenerate damaged tissue. 

Dr. Montero shares early insights from the first-in-human clinical trial of CAR Tregs for GVHD, noting promising safety and signs of durable benefit in patients who had exhausted other treatment options. 

Looking ahead, Dr. Montero envisions expanding this technology to tackle type 1 diabetes and other autoimmune conditions, driven by a collective dream to move beyond symptom management toward true cures.  

Follow Us: 

Presented by City of Hope: www.CityOfHope.org

]]> Thu, 11 Dec 2025 05:00:00 +0000 stories@amazemedialabs.com (Dr. Enrique Montero, Prue Buxton, Michael Harkins, Matt Hamil, Justin Delos Reyes, Dr. Monty Pal) https://on-the-edge-of-breakthrough.simplecast.com/episodes/the-quest-to-cure-exploring-the-latest-frontiers-in-autoimmune-disease-treatment-ZQ3KdMxz In this episode of On the Edge of Breakthrough: Voices of Cancer Research, Dr. Monty Pal welcomes Dr. Enrique Montero, research professor within the Arthur Riggs Diabetes & Metabolism Research Institute, to discuss his global journey in immunology and the pioneering work underway at City of Hope. Dr. Montero shares how early clinical experiences with lupus inspired his lifelong mission to bridge basic science and clinical application, leading to innovative therapies for cancer and autoimmune diseases. 

The episode dives into the significance of the CD6 molecule on T cells - how its overexpression drives inflammation in conditions like type 1 diabetes and graft-versus-host disease (GVHD). The duo discusses the development of targeted monoclonal antibodies and a groundbreaking approach using genetically modified regulatory T cells—CAR Tregs—to modulate immune responses, aiming not just to control disease but to regenerate damaged tissue. 

Dr. Montero shares early insights from the first-in-human clinical trial of CAR Tregs for GVHD, noting promising safety and signs of durable benefit in patients who had exhausted other treatment options. 

Looking ahead, Dr. Montero envisions expanding this technology to tackle type 1 diabetes and other autoimmune conditions, driven by a collective dream to move beyond symptom management toward true cures.  

Follow Us: 

Presented by City of Hope: www.CityOfHope.org

]]> The Quest to Cure: Exploring the Latest Frontiers in Autoimmune Disease Treatment Dr. Enrique Montero, Prue Buxton, Michael Harkins, Matt Hamil, Justin Delos Reyes, Dr. Monty Pal 00:39:04 Dr. Monty Pal welcomes Dr. Enrique Montero, research professor within the Arthur Riggs Diabetes & Metabolism Research Institute, to discuss his global journey in immunology and the pioneering work underway at City of Hope. The episode dives into the significance of the CD6 molecule on T cells - how its overexpression drives inflammation in conditions like type 1 diabetes and graft-versus-host disease (GVHD). Dr. Montero shares early insights from the first-in-human clinical trial of CAR Tregs for GVHD, noting promising safety and signs of durable benefit in patients who had exhausted other treatment options, and outlines the vision for expanding this technology to tackle type 1 diabetes and other autoimmune conditions. Dr. Monty Pal welcomes Dr. Enrique Montero, research professor within the Arthur Riggs Diabetes & Metabolism Research Institute, to discuss his global journey in immunology and the pioneering work underway at City of Hope. The episode dives into the significance of the CD6 molecule on T cells - how its overexpression drives inflammation in conditions like type 1 diabetes and graft-versus-host disease (GVHD). Dr. Montero shares early insights from the first-in-human clinical trial of CAR Tregs for GVHD, noting promising safety and signs of durable benefit in patients who had exhausted other treatment options, and outlines the vision for expanding this technology to tackle type 1 diabetes and other autoimmune conditions. what is cancer, cancer center, graft-versus-host disease, cancer diagnosis, gvhd, cancer treatment, on the edge of breakthrough, diabetes and cancer, t cells, cancer research, science, car-tregs, city of hope false full 4 3 8481850b-15b9-447a-a761-348a2c3b9f5b Translating Discovery: Shaping Tomorrow’s Prostate Cancer Therapies Wed, 26 Nov 2025 05:00:00 +0000 stories@amazemedialabs.com (Dr. Tanya Dorff, Dr. Monty Pal) https://on-the-edge-of-breakthrough.simplecast.com/episodes/translating-discovery-unlocking-tomorrows-prostate-cancer-therapies-wY8ufKtY Translating Discovery: Shaping Tomorrow’s Prostate Cancer Therapies Dr. Tanya Dorff, Dr. Monty Pal 00:31:51 In this episode of On the Edge of Breakthrough: Voices of Cancer Research, Dr. Monty Pal welcomes Dr. Tanya Dorff, professor in the Department of Medical Oncology & Therapeutics Research and section chief of the Genitourinary Disease Program at City of Hope. Together they dive into Dorff’s pioneering work in immunotherapy for prostate cancer - from the challenges of moving treatments from bench to bedside, to the importance of collaborative team-science, and the role of deep biological correlates in informing future studies. Beyond her clinical and research achievements, Dr. Dorff reflects on mentorship, work-life balance, and the importance of supporting diversity of thought in academic medicine. She shares how creative pursuits help her recharge and offers advice for aspiring oncologists to pursue their passions and embrace bold leaps at the edge of breakthrough. Tune in to discover how clinical innovation, collaboration, and a patient-centered approach are the secret sauce driving advances in cancer care. Follow Us: • LinkedIn @city-of-hope • X @cityofhope • Facebook @cityofhope • Instagram @cityofhope Presented by City of Hope: www.CityOfHope.org In this episode of On the Edge of Breakthrough: Voices of Cancer Research, Dr. Monty Pal welcomes Dr. Tanya Dorff, professor in the Department of Medical Oncology & Therapeutics Research and section chief of the Genitourinary Disease Program at City of Hope. Together they dive into Dorff’s pioneering work in immunotherapy for prostate cancer - from the challenges of moving treatments from bench to bedside, to the importance of collaborative team-science, and the role of deep biological correlates in informing future studies. Beyond her clinical and research achievements, Dr. Dorff reflects on mentorship, work-life balance, and the importance of supporting diversity of thought in academic medicine. She shares how creative pursuits help her recharge and offers advice for aspiring oncologists to pursue their passions and embrace bold leaps at the edge of breakthrough. Tune in to discover how clinical innovation, collaboration, and a patient-centered approach are the secret sauce driving advances in cancer care. Follow Us: • LinkedIn @city-of-hope • X @cityofhope • Facebook @cityofhope • Instagram @cityofhope Presented by City of Hope: www.CityOfHope.org immunotherapy, bispecific antibodies, what is cancer, cancer center, cancer treatment, prostate cancer, on the edge of breakthrough, genitourinary disease, mentorship, cancer research, city of hope, car-t false full 3 3 4b48ce90-bc9f-45df-8ba5-49e301ae9b84 Asking the Impossible: How Bold Questions are Unlocking Diabetes Biggest Breakthroughs From a small Sicilian town to the forefront of diabetes research, Dr. Pugliese’s story is one of relentless curiosity and hope. He shares how early family experiences and clinical frustrations inspired his lifelong mission to improve outcomes type 1 diabetes.

The conversation delves into the role of viruses and the microbiome in triggering type 1 diabetes. Dr. Pugliese describes his leadership in the Network for Pancreatic Organ Donors with Diabetes (nPOD), which has enabled collaborative studies showing evidence of chronic viral infections in the pancreas and their potential contribution to disease onset.

This episode also dissects how generous giving becomes the driving force behind groundbreaking research and scientific breakthroughs. Dr. Pugliese shares details of a bold, new nationwide clinical trial led by City of Hope, inspired by philanthropic support from the Wanek Family Project. The innovative trial will assess a combination of approved therapies to investigate ways to preserve insulin secretion and control the autoimmune process in newly diagnosed patients, aiming to accelerate progress toward a cure.

 Tune in to discover how Dr. Pugliese’s translational diabetes research, collaborative spirit, and commitment to mentorship are driving breakthroughs in diabetes care.  

Follow Us:

• LinkedIn @city-of-hope

• X @cityofhope

• Facebook @cityofhope

• Instagram @cityofhope

Presented by City of Hope: www.CityOfHope.org

 

]]> Tue, 11 Nov 2025 05:00:00 +0000 stories@amazemedialabs.com (Dr. Alberto Pugliese, Dr. Monty Pal) https://on-the-edge-of-breakthrough.simplecast.com/episodes/asking-the-impossible-how-bold-questions-are-unlocking-diabetes-biggest-breakthroughs-bCvFrqwe From a small Sicilian town to the forefront of diabetes research, Dr. Pugliese’s story is one of relentless curiosity and hope. He shares how early family experiences and clinical frustrations inspired his lifelong mission to improve outcomes type 1 diabetes.

The conversation delves into the role of viruses and the microbiome in triggering type 1 diabetes. Dr. Pugliese describes his leadership in the Network for Pancreatic Organ Donors with Diabetes (nPOD), which has enabled collaborative studies showing evidence of chronic viral infections in the pancreas and their potential contribution to disease onset.

This episode also dissects how generous giving becomes the driving force behind groundbreaking research and scientific breakthroughs. Dr. Pugliese shares details of a bold, new nationwide clinical trial led by City of Hope, inspired by philanthropic support from the Wanek Family Project. The innovative trial will assess a combination of approved therapies to investigate ways to preserve insulin secretion and control the autoimmune process in newly diagnosed patients, aiming to accelerate progress toward a cure.

 Tune in to discover how Dr. Pugliese’s translational diabetes research, collaborative spirit, and commitment to mentorship are driving breakthroughs in diabetes care.  

Follow Us:

• LinkedIn @city-of-hope

• X @cityofhope

• Facebook @cityofhope

• Instagram @cityofhope

Presented by City of Hope: www.CityOfHope.org

 

]]> Asking the Impossible: How Bold Questions are Unlocking Diabetes Biggest Breakthroughs Dr. Alberto Pugliese, Dr. Monty Pal 00:51:26 In this episode of On the Edge of Breakthrough: Voices of Cancer Research, Dr. Monty Pal sits down with Dr. Alberto Pugliese, Samuel Rahbar Chair in Diabetes & Drug Discovery, chair of the Department of Diabetes Immunology and director of The Wanek Family Project for Type 1 Diabetes. Tune in to discover how Dr. Pugliese’s translational diabetes research, collaborative spirit, and commitment to mentorship are driving breakthroughs in diabetes care. In this episode of On the Edge of Breakthrough: Voices of Cancer Research, Dr. Monty Pal sits down with Dr. Alberto Pugliese, Samuel Rahbar Chair in Diabetes & Drug Discovery, chair of the Department of Diabetes Immunology and director of The Wanek Family Project for Type 1 Diabetes. Tune in to discover how Dr. Pugliese’s translational diabetes research, collaborative spirit, and commitment to mentorship are driving breakthroughs in diabetes care. type 1 diabetes, oteob, what is cancer, episode 2, cancer diagnosis, cancer treatment, diabetes research, pugliese, on the edge of breakthrough, oncology research, diabetes and cancer, diabetes, cancer research, city of hope false full 2 3 45f181da-618c-4e55-a81a-0bf96f85813f Movement as Medicine: The Science Reshaping Oncology In this episode of "On the Edge of Breakthrough: Voices of Cancer Research," host Dr. Monty Pal welcomes Dr. Lee Jones, Head of the Exercise Oncology Program in the Department of Medicine at City of Hope, to discuss how exercise science is helping reshape cancer treatment and care. Dr. Jones shares his journey from the UK to City of Hope, highlighting the challenges and breakthroughs in establishing exercise as a vital part of oncology research.  

He explains how the field of exercise oncology has taken lessons from NASA and their work to prepare astronauts going to and coming back from space to improve outcomes for cancer patients throughout their treatment journey. 

The episode explores how breast cancer studies lay the groundwork for integrating exercise into survivorship and treatment and they dive into landmark trials, such as the CHALLENGE study, which showed exercise can improve survival for colorectal cancer patients. Dr. Jones emphasizes the need for rigorous, drug-like trial designs to truly measure the impact of exercise interventions. He argues innovative approaches such as decentralized trials, using remote monitoring and home-based exercise equipment are critical to expand access and collect real-time data. 

Dr. Jones shares a sneak peak of new studies launching in prostate cancer, high-risk populations, and collaborations with national research networks. His vision is to move beyond a cancer-cell focus, embracing holistic interventions that consider the patient’s physiology and environment. 

Tune in to hear how City of Hope is pushing the boundaries of cancer research and care. 

Visit On The Edge of Breakthrough to learn more.

Follow Us: 

Presented by City of Hope: www.CityOfHope.org

]]> Tue, 28 Oct 2025 04:00:00 +0000 stories@amazemedialabs.com (Dr. Lee Jones, Dr. Monty Pal) https://youtu.be/dCHCNC-VLWs In this episode of "On the Edge of Breakthrough: Voices of Cancer Research," host Dr. Monty Pal welcomes Dr. Lee Jones, Head of the Exercise Oncology Program in the Department of Medicine at City of Hope, to discuss how exercise science is helping reshape cancer treatment and care. Dr. Jones shares his journey from the UK to City of Hope, highlighting the challenges and breakthroughs in establishing exercise as a vital part of oncology research.  

He explains how the field of exercise oncology has taken lessons from NASA and their work to prepare astronauts going to and coming back from space to improve outcomes for cancer patients throughout their treatment journey. 

The episode explores how breast cancer studies lay the groundwork for integrating exercise into survivorship and treatment and they dive into landmark trials, such as the CHALLENGE study, which showed exercise can improve survival for colorectal cancer patients. Dr. Jones emphasizes the need for rigorous, drug-like trial designs to truly measure the impact of exercise interventions. He argues innovative approaches such as decentralized trials, using remote monitoring and home-based exercise equipment are critical to expand access and collect real-time data. 

Dr. Jones shares a sneak peak of new studies launching in prostate cancer, high-risk populations, and collaborations with national research networks. His vision is to move beyond a cancer-cell focus, embracing holistic interventions that consider the patient’s physiology and environment. 

Tune in to hear how City of Hope is pushing the boundaries of cancer research and care. 

Visit On The Edge of Breakthrough to learn more.

Follow Us: 

Presented by City of Hope: www.CityOfHope.org

]]> Movement as Medicine: The Science Reshaping Oncology Dr. Lee Jones, Dr. Monty Pal 00:55:41 In this episode of "On the Edge of Breakthrough: Voices of Cancer Research," host Dr. Monty Pal welcomes Dr. Lee Jones, Head of the Exercise Oncology Program in the Department of Medicine at City of Hope, to discuss how exercise science is helping reshape cancer treatment and care. Dr. Jones shares his journey from the UK to City of Hope, highlighting the challenges and breakthroughs in establishing exercise as a vital part of oncology research. He explains how the field of exercise oncology has taken lessons from NASA and their work to prepare astronauts going to and coming back from space to improve outcomes for cancer patients throughout their treatment journey. In this episode of "On the Edge of Breakthrough: Voices of Cancer Research," host Dr. Monty Pal welcomes Dr. Lee Jones, Head of the Exercise Oncology Program in the Department of Medicine at City of Hope, to discuss how exercise science is helping reshape cancer treatment and care. Dr. Jones shares his journey from the UK to City of Hope, highlighting the challenges and breakthroughs in establishing exercise as a vital part of oncology research. He explains how the field of exercise oncology has taken lessons from NASA and their work to prepare astronauts going to and coming back from space to improve outcomes for cancer patients throughout their treatment journey. exercise oncolgy, oteob, podcast, lee jones, episode 1, what is cancer, cancer center, cancer diagnosis, cancer treatment, exercise and cancer, monty pal, on the edge of breakthrough, oncology research, exercise scientist, cancer research, science, city of hope false full 1 3 9cc913a8-ee05-4eda-ae87-c251af28f4cf How Team Science is Driving Lung Cancer Breakthroughs In this episode of On the Edge of Breakthrough: Voices of Cancer Research, Dr. Monty Pal sits down with Dr. Loretta Erhunmwunsee, a thoracic surgeon and lung cancer researcher at City of Hope,.

From her roots in underserved communities to today, where she is at the forefront of lung cancer research, Dr. Erhunmwunsee brings a unique perspective to understanding how environments and where we live can shape our health. Her latest groundbreaking research looks at how air pollution and neighborhood locations may not only increase cancer risk — but also influence tumor biology. She explores why diversity in healthcare matters and shares her vision for making leading-edge cancer care accessible to all.

Follow Us

Presented by City Of Hope
www.CityOfHope.org

]]> Wed, 20 Aug 2025 04:00:00 +0000 stories@amazemedialabs.com (Dr. Loretta Erhunmwunsee, Dr. Monty Pal) https://on-the-edge-of-breakthrough.simplecast.com/episodes/how-team-science-is-driving-lung-cancer-breakthroughs-bZT4cfxE In this episode of On the Edge of Breakthrough: Voices of Cancer Research, Dr. Monty Pal sits down with Dr. Loretta Erhunmwunsee, a thoracic surgeon and lung cancer researcher at City of Hope,.

From her roots in underserved communities to today, where she is at the forefront of lung cancer research, Dr. Erhunmwunsee brings a unique perspective to understanding how environments and where we live can shape our health. Her latest groundbreaking research looks at how air pollution and neighborhood locations may not only increase cancer risk — but also influence tumor biology. She explores why diversity in healthcare matters and shares her vision for making leading-edge cancer care accessible to all.

Follow Us

Presented by City Of Hope
www.CityOfHope.org

]]> How Team Science is Driving Lung Cancer Breakthroughs Dr. Loretta Erhunmwunsee, Dr. Monty Pal 00:32:05 Dr. Loretta Erhunmwunsee explores her latest groundbreaking research investigating the impact of air pollution on lung cancer and shares how team science is critical to advancing cancer care for all. Dr. Loretta Erhunmwunsee explores her latest groundbreaking research investigating the impact of air pollution on lung cancer and shares how team science is critical to advancing cancer care for all. false full 6 2 56e847d9-c7a0-4af1-8539-8945b41776ed Expanding the Reach of TIL Therapy: What Will it Take? What does it take to bring tumor-infiltrating lymphocyte (TIL) therapy to more patients and make the therapy more effective for those already eligible?

In this episode of Edge of Breakthrough, Dr. Monty Pal sits down with Dr. Kelly Mahuron, a surgical oncologist at City of Hope, to unpack how TIL therapy is evolving. From identifying eligible patients and surgical harvesting of TILs to cell expansion and reinfusion, Dr. Mahuron breaks down the entire  process of TIL therapy, highlighting how her cross-disciplinary team is working to improve patient outcomes, reduce toxicity, and eventually expand treatment beyond melanoma.

They also explore the next generation of TILs  f, and  how oncolytic viruses and modified immune environments might bring TILs to more resistant cancers such as pancreatic and colorectal tumors.

Learn how surgical precision, immunotherapy, and translational research come together to push the boundaries of what's possible in cancer treatment. . Tune in to the full conversation now.

Follow Us

Presented by City Of Hope
www.CityOfHope.org

]]> Tue, 5 Aug 2025 04:00:00 +0000 stories@amazemedialabs.com (Dr. Kelly Mahuron, Dr. Monty Pal) https://on-the-edge-of-breakthrough.simplecast.com/episodes/expanding-the-reach-of-til-therapy-what-will-it-take-ryL76Wx7 What does it take to bring tumor-infiltrating lymphocyte (TIL) therapy to more patients and make the therapy more effective for those already eligible?

In this episode of Edge of Breakthrough, Dr. Monty Pal sits down with Dr. Kelly Mahuron, a surgical oncologist at City of Hope, to unpack how TIL therapy is evolving. From identifying eligible patients and surgical harvesting of TILs to cell expansion and reinfusion, Dr. Mahuron breaks down the entire  process of TIL therapy, highlighting how her cross-disciplinary team is working to improve patient outcomes, reduce toxicity, and eventually expand treatment beyond melanoma.

They also explore the next generation of TILs  f, and  how oncolytic viruses and modified immune environments might bring TILs to more resistant cancers such as pancreatic and colorectal tumors.

Learn how surgical precision, immunotherapy, and translational research come together to push the boundaries of what's possible in cancer treatment. . Tune in to the full conversation now.

Follow Us

Presented by City Of Hope
www.CityOfHope.org

]]> Expanding the Reach of TIL Therapy: What Will it Take? Dr. Kelly Mahuron, Dr. Monty Pal 00:38:47 Dr. Mahuron shares how tumor-infiltrating lymphocyte (TIL) therapy is evolving to reach more patients and improve cancer outcomes. Dr. Mahuron shares how tumor-infiltrating lymphocyte (TIL) therapy is evolving to reach more patients and improve cancer outcomes. false full 5 2 0f814d84-127a-4dd2-8390-9594c16aac9e Rewriting the Rules of Cellular Therapy In this episode of On the Edge of Breakthrough, Dr. Monty Pal is joined by Dr. Stephen Forman, a giant of cancer care and  hematologic malignancies and pioneer of cellular immunotherapy. 

Dr. Forman reflects on decades of progress in bone marrow transplantation, CAR T cell therapy, and the future of cellular therapies. But this conversation isn’t just about lab science. It’s about the human side of innovation: the infrastructure, access, and emotional support needed to truly care for patients through some of the most complex treatments in cancer care.

Dr. Forman also explains the urgency of expanding healthcare access, and reveals the  best practices for building scalable models to deliver the next-generation immunotherapy for patients who need them now.

Listen as they unpack what it means to move from an innovative experiment in the lab  to real impact on the front lines of cancer care.

Follow Us

Presented by City Of Hope
www.CityOfHope.org

]]> Tue, 22 Jul 2025 04:00:00 +0000 stories@amazemedialabs.com (Dr. Stephen Forman, Dr. Monty Pal) https://on-the-edge-of-breakthrough.simplecast.com/episodes/rewriting-the-rules-of-cellular-therapy-0KQ8ySj4 In this episode of On the Edge of Breakthrough, Dr. Monty Pal is joined by Dr. Stephen Forman, a giant of cancer care and  hematologic malignancies and pioneer of cellular immunotherapy. 

Dr. Forman reflects on decades of progress in bone marrow transplantation, CAR T cell therapy, and the future of cellular therapies. But this conversation isn’t just about lab science. It’s about the human side of innovation: the infrastructure, access, and emotional support needed to truly care for patients through some of the most complex treatments in cancer care.

Dr. Forman also explains the urgency of expanding healthcare access, and reveals the  best practices for building scalable models to deliver the next-generation immunotherapy for patients who need them now.

Listen as they unpack what it means to move from an innovative experiment in the lab  to real impact on the front lines of cancer care.

Follow Us

Presented by City Of Hope
www.CityOfHope.org

]]> Rewriting the Rules of Cellular Therapy Dr. Stephen Forman, Dr. Monty Pal 00:47:37 Dr. Stephen Forman shares the past, present, and future of cellular therapy and how City of Hope is building care systems to reach more patients. Dr. Stephen Forman shares the past, present, and future of cellular therapy and how City of Hope is building care systems to reach more patients. false full 4 2 834a85bb-c9d4-46ad-88ee-e4b19d12d436 At the Crossroads of Cancer and Metabolism In this episode of On the Edge of Breakthrough, host Dr. Monty Pal sits down with Dr. Charles Brenner, an internationally recognized expert in metabolism and the founding Chair of the Department of Diabetes & Cancer Metabolism at City of Hope. Together, they explore the metabolic links between diabetes, obesity, and cancer, and how understanding those connections could lead to new ways to prevent and treat multiple diseases.

Dr. Brenner shares insights from his research into lean fatty liver disease (otherwise known as metabolic dysfunction-associated steatotic liver disease or MASLD), and how certain genetic factors may be quietly driving both metabolic dysfunction and cancer risk. They also discuss the rise of GLP-1 therapies and how a new class of compounds targeting FGF21 might offer a potential  new therapeutic option that could help curb sugar cravings and support liver health.

This episode takes listeners deep into the science of energy balance, NAD metabolism, fatty liver disease, and what it truly means to be on the edge of a breakthrough.

Tune in now and stay updated on the science shaping the future of cancer care.

Follow Us

Presented by City Of Hope
www.CityOfHope.org

]]> Tue, 8 Jul 2025 04:00:00 +0000 stories@amazemedialabs.com (Dr. Monty Pal, Dr. Charles Brenner) https://on-the-edge-of-breakthrough.simplecast.com/episodes/at-the-crossroads-of-cancer-and-metabolism-JvRm4jsh In this episode of On the Edge of Breakthrough, host Dr. Monty Pal sits down with Dr. Charles Brenner, an internationally recognized expert in metabolism and the founding Chair of the Department of Diabetes & Cancer Metabolism at City of Hope. Together, they explore the metabolic links between diabetes, obesity, and cancer, and how understanding those connections could lead to new ways to prevent and treat multiple diseases.

Dr. Brenner shares insights from his research into lean fatty liver disease (otherwise known as metabolic dysfunction-associated steatotic liver disease or MASLD), and how certain genetic factors may be quietly driving both metabolic dysfunction and cancer risk. They also discuss the rise of GLP-1 therapies and how a new class of compounds targeting FGF21 might offer a potential  new therapeutic option that could help curb sugar cravings and support liver health.

This episode takes listeners deep into the science of energy balance, NAD metabolism, fatty liver disease, and what it truly means to be on the edge of a breakthrough.

Tune in now and stay updated on the science shaping the future of cancer care.

Follow Us

Presented by City Of Hope
www.CityOfHope.org

]]> At the Crossroads of Cancer and Metabolism Dr. Monty Pal, Dr. Charles Brenner 00:37:38 Dr. Charles Brenner explores the metabolic links between cancer, diabetes, NAD, and the future of liver-focused therapies. Dr. Charles Brenner explores the metabolic links between cancer, diabetes, NAD, and the future of liver-focused therapies. false full 3 2 eec5ac9b-899e-4b9c-95c4-cb3065f9acb4 Three Leaders, One Vision: Principles for Transforming Cancer Care Delivery In this special episode of On the Edge of Breakthrough, recorded live at the 2025 ASCO Annual Meeting, host Dr. Monty Pal sits down with two of City of Hope’s newest clinical leaders: Dr. Walter Stadler, Chief Clinical Officer at City of Hope Chicago, and Dr. Alan Bryce, Chief Clinical Officer at Hope Phoenix.

Together, they explore what it takes to build a national model for research-driven care, from creating system-wide infrastructure for precision medicine to integrating AI across core services like  pathology, real-time cross-network collaboration, and genomic innovation throughout  40+ sites. The episode dives into the growing complexity of cancer treatment, the burden on individual providers, and how building smarter systems can accelerate access to trials, for all  communities.

The discussion touches on simplifying clinical trial design, rethinking dose strategies, and the institutional commitment to pushing forward both early detection and long-term survivorship.

If you're interested in where oncology is headed next—from both a research and systems perspective—this episode is a must-listen.

Follow Us

Presented by City Of Hope
www.CityOfHope.org

]]> Tue, 24 Jun 2025 04:00:00 +0000 stories@amazemedialabs.com (Dr. Monty Pal, Dr. Walter Stadler, Dr. Alan Bryce) https://on-the-edge-of-breakthrough.simplecast.com/episodes/three-leaders-one-vision-principles-for-transforming-cancer-care-delivery-BxPrC3tN In this special episode of On the Edge of Breakthrough, recorded live at the 2025 ASCO Annual Meeting, host Dr. Monty Pal sits down with two of City of Hope’s newest clinical leaders: Dr. Walter Stadler, Chief Clinical Officer at City of Hope Chicago, and Dr. Alan Bryce, Chief Clinical Officer at Hope Phoenix.

Together, they explore what it takes to build a national model for research-driven care, from creating system-wide infrastructure for precision medicine to integrating AI across core services like  pathology, real-time cross-network collaboration, and genomic innovation throughout  40+ sites. The episode dives into the growing complexity of cancer treatment, the burden on individual providers, and how building smarter systems can accelerate access to trials, for all  communities.

The discussion touches on simplifying clinical trial design, rethinking dose strategies, and the institutional commitment to pushing forward both early detection and long-term survivorship.

If you're interested in where oncology is headed next—from both a research and systems perspective—this episode is a must-listen.

Follow Us

Presented by City Of Hope
www.CityOfHope.org

]]> Three Leaders, One Vision: Principles for Transforming Cancer Care Delivery Dr. Monty Pal, Dr. Walter Stadler, Dr. Alan Bryce 00:43:59 Dr. Walter Stadler & Dr. Alan Bryce share how City of Hope is building a national system for smarter research, greater access, and better cancer care. Dr. Walter Stadler & Dr. Alan Bryce share how City of Hope is building a national system for smarter research, greater access, and better cancer care. false full 2 2 3a8f131a-0b01-47e8-858c-927d8194e327 How a Bold Yes Became a Scientific Breakthrough Welcome back to Season 2  On the Edge of Breakthrough: Voices of Cancer Research. In this powerful episode, Dr. Monty Pal welcomes Dr. Linda Malkas, Dean of Translational Sciences at City of Hope, for a conversation that spans childhood stargazing in Queens to leading one of the most ambitious cancer drug developments in recent history.

Dr. Malkas shares how a chance encounter with a grieving father sparked her quest to take on an “undruggable” target, resulting in AOH1996, a promising molecule designed to selectively attack cancer cells while sparing healthy ones. Named in memory of 8-year-old Ana Olivia Healy, the drug is now moving through clinical trials and showing potential to improve standard of care treatments across multiple cancers.

This episode dives into the science, the setbacks, and the synchronicity that fueled this journey, from organic chemistry and DNA fascination to late-night lab work, multidisciplinary collaboration, and the unique ecosystem at City of Hope that made it all possible.

It’s a remarkable story of science, heart, and the human drive to say “yes” to the impossible. Listen now.

Follow Us

Presented by City Of Hope
www.CityOfHope.org

]]> Tue, 10 Jun 2025 04:00:00 +0000 stories@amazemedialabs.com (Dr. Monty Pal, Dr. Linda Malkas) https://on-the-edge-of-breakthrough.simplecast.com/episodes/how-a-bold-yes-became-a-scientific-breakthrough-443_YM72 Welcome back to Season 2  On the Edge of Breakthrough: Voices of Cancer Research. In this powerful episode, Dr. Monty Pal welcomes Dr. Linda Malkas, Dean of Translational Sciences at City of Hope, for a conversation that spans childhood stargazing in Queens to leading one of the most ambitious cancer drug developments in recent history.

Dr. Malkas shares how a chance encounter with a grieving father sparked her quest to take on an “undruggable” target, resulting in AOH1996, a promising molecule designed to selectively attack cancer cells while sparing healthy ones. Named in memory of 8-year-old Ana Olivia Healy, the drug is now moving through clinical trials and showing potential to improve standard of care treatments across multiple cancers.

This episode dives into the science, the setbacks, and the synchronicity that fueled this journey, from organic chemistry and DNA fascination to late-night lab work, multidisciplinary collaboration, and the unique ecosystem at City of Hope that made it all possible.

It’s a remarkable story of science, heart, and the human drive to say “yes” to the impossible. Listen now.

Follow Us

Presented by City Of Hope
www.CityOfHope.org

]]> How a Bold Yes Became a Scientific Breakthrough Dr. Monty Pal, Dr. Linda Malkas 00:47:08 Dr. Linda Malkas shares the story behind AOH1996—how one bold “yes” led to a new cancer drug and a legacy built from love and science. Dr. Linda Malkas shares the story behind AOH1996—how one bold “yes” led to a new cancer drug and a legacy built from love and science. false full 1 2 dde2543d-53a7-4d46-896b-0cb7476c55dc Building the First AI Agent for Cancer Research In this episode of On the Edge of Breakthrough: Voices of Cancer Research, Dr. Monty Pal sits down with Dr. Enrique Velazquez Villarreal, a physician-scientist in City of Hope’s Department of Integrative Translational Sciences, whose path into medicine and research is anything but typical.

Dr. Velazquez Villarreal talks about growing up in Mexico, entering medical school at 17, and the many mentors—who shaped his decision to pursue oncology - three of whom he lost to colorectal cancer He shares how his early exposure to both surgery and underserved communities led him to seek answers not only through the scalpel, but through software. The episode dives into his groundbreaking work integrating clinical data with genomics, artificial intelligence, and multi-omics tools to tackle one of the most alarming trends in oncology: the rise of colorectal cancer in young Hispanic patients. He also unpacks his mission to make AI useful, accessible, and truly impactful in the clinic—not just in research papers.

This is a deeply thoughtful conversation about data, technology, and the very human reason behind why it all matters.

Follow Us

Presented by City Of Hope

www.CityOfHope.org

]]> Tue, 6 May 2025 04:00:00 +0000 stories@amazemedialabs.com (Dr. Monty Pal, Dr. Enrique Velazquez Villarreal) https://on-the-edge-of-breakthrough.simplecast.com/episodes/building-the-first-ai-agent-for-cancer-research-4bHXSs3R In this episode of On the Edge of Breakthrough: Voices of Cancer Research, Dr. Monty Pal sits down with Dr. Enrique Velazquez Villarreal, a physician-scientist in City of Hope’s Department of Integrative Translational Sciences, whose path into medicine and research is anything but typical.

Dr. Velazquez Villarreal talks about growing up in Mexico, entering medical school at 17, and the many mentors—who shaped his decision to pursue oncology - three of whom he lost to colorectal cancer He shares how his early exposure to both surgery and underserved communities led him to seek answers not only through the scalpel, but through software. The episode dives into his groundbreaking work integrating clinical data with genomics, artificial intelligence, and multi-omics tools to tackle one of the most alarming trends in oncology: the rise of colorectal cancer in young Hispanic patients. He also unpacks his mission to make AI useful, accessible, and truly impactful in the clinic—not just in research papers.

This is a deeply thoughtful conversation about data, technology, and the very human reason behind why it all matters.

Follow Us

Presented by City Of Hope

www.CityOfHope.org

]]> Building the First AI Agent for Cancer Research Dr. Monty Pal, Dr. Enrique Velazquez Villarreal 00:49:09 Dr. Enrique Velazquez Villarreal on AI, genomics, and why young Latinos are at the heart of his work to improve colorectal cancer research and care. Dr. Enrique Velazquez Villarreal on AI, genomics, and why young Latinos are at the heart of his work to improve colorectal cancer research and care. false full 6 1 8c90986b-2394-4749-a6e2-a02a8e15feaa Humanizing Cancer Treatment Through Whole-Person Care In this episode of On the Edge of Breakthrough: Voices of Cancer Research, Dr. Monty Pal sits down with Dr. Betty Ferrell, trailblazing nurse-scientist and director of the Division of Nursing Research and Education at City of Hope. Known globally for her foundational work in quality of life, pain management, and palliative care, Dr. Ferrell reflects on her nearly four decades of research, mentorship, and advocacy that have reshaped how we define patient-centered cancer care.

Together they trace her journey from bedside nursing in Oklahoma to spearheading research that has influenced standards of care across disciplines—from bone marrow transplantation and thoracic surgery, to early-phase clinical trials. Dr. Ferrell shares her international collaborations, including her work in Ethiopia with colleague Dr. Lesley Taylor, which are driving change in some of the most resource-constrained settings.

This episode is a reminder that treating cancer isn’t just about targeting disease—it’s about recognizing the full human experience behind it.

Follow Us

Presented by City Of Hope

www.CityOfHope.org

]]> Tue, 22 Apr 2025 04:00:00 +0000 stories@amazemedialabs.com (Dr. Monty Pal, Dr. Betty Ferrell) https://on-the-edge-of-breakthrough.simplecast.com/episodes/humanizing-cancer-treatment-through-whole-person-care-yOICds5I In this episode of On the Edge of Breakthrough: Voices of Cancer Research, Dr. Monty Pal sits down with Dr. Betty Ferrell, trailblazing nurse-scientist and director of the Division of Nursing Research and Education at City of Hope. Known globally for her foundational work in quality of life, pain management, and palliative care, Dr. Ferrell reflects on her nearly four decades of research, mentorship, and advocacy that have reshaped how we define patient-centered cancer care.

Together they trace her journey from bedside nursing in Oklahoma to spearheading research that has influenced standards of care across disciplines—from bone marrow transplantation and thoracic surgery, to early-phase clinical trials. Dr. Ferrell shares her international collaborations, including her work in Ethiopia with colleague Dr. Lesley Taylor, which are driving change in some of the most resource-constrained settings.

This episode is a reminder that treating cancer isn’t just about targeting disease—it’s about recognizing the full human experience behind it.

Follow Us

Presented by City Of Hope

www.CityOfHope.org

]]> Humanizing Cancer Treatment Through Whole-Person Care Dr. Monty Pal, Dr. Betty Ferrell 00:47:34 Dr. Betty Ferrell on her global legacy in palliative care and why whole-person treatment is as crucial as fighting cancer itself. Dr. Betty Ferrell on her global legacy in palliative care and why whole-person treatment is as crucial as fighting cancer itself. false full 5 1 df39aaa9-3d10-40ea-b4cc-8d40e5f05e6e Pushing the Limits of Cancer Research and Surgery In this episode of On the Edge of Breakthrough: Voices of Cancer Research, Dr. Monty Pal talks with Mustafa Raoof, a leading surgical oncologist and physician-scientist at City of Hope, about the challenges and potential in treating some of the toughest cancers.

Dr. Raoof reflects on his path - from boarding school in Pakistan to pioneering new techniques in peritoneal metastasis treatment at a world renowned cancer center, including the promising intraperitoneal therapy known as Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC). He breaks down his lab's latest work on DNA repair in pancreatic cancer, shares his perspectives on the value of making research more accessible across low-resource settings, and discusses how he balances life as a researcher, surgeon, and his most important role as a dad.

This is a grounded, thoughtful conversation that spotlights how innovation meets real-world limitations, and why collaboration  —not just within institutions, but across borders — is more essential than ever.

Follow Us

Presented by City Of Hope

www.CityOfHope.org

]]> Tue, 8 Apr 2025 04:00:00 +0000 stories@amazemedialabs.com (Dr. Monty Pal, Dr. Mustafa Raoof) https://on-the-edge-of-breakthrough.simplecast.com/episodes/pushing-the-limits-of-cancer-research-and-surgery-_xF3aQHX In this episode of On the Edge of Breakthrough: Voices of Cancer Research, Dr. Monty Pal talks with Mustafa Raoof, a leading surgical oncologist and physician-scientist at City of Hope, about the challenges and potential in treating some of the toughest cancers.

Dr. Raoof reflects on his path - from boarding school in Pakistan to pioneering new techniques in peritoneal metastasis treatment at a world renowned cancer center, including the promising intraperitoneal therapy known as Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC). He breaks down his lab's latest work on DNA repair in pancreatic cancer, shares his perspectives on the value of making research more accessible across low-resource settings, and discusses how he balances life as a researcher, surgeon, and his most important role as a dad.

This is a grounded, thoughtful conversation that spotlights how innovation meets real-world limitations, and why collaboration  —not just within institutions, but across borders — is more essential than ever.

Follow Us

Presented by City Of Hope

www.CityOfHope.org

]]> Pushing the Limits of Cancer Research and Surgery Dr. Monty Pal, Dr. Mustafa Raoof 00:38:55 Dr. Mustafa Raoof on PIPAC, pancreatic cancer research, and how global innovation can shape the next chapter of surgical oncology. Dr. Mustafa Raoof on PIPAC, pancreatic cancer research, and how global innovation can shape the next chapter of surgical oncology. false full 4 1 c2d51a03-e64f-46fc-9c89-16a3952df171 Breaking Barriers in Cancer Care: Expanding Access, Innovation & Integrative Medicine In this episode of On the Edge of Breakthrough: Voices of Cancer Research, Dr. Monty Pal speaks with Edward S. Kim, M.D., M.B.A., the physician-in-chief of City of Hope Orange County and Vice Physician-in-Chief of City of Hope National Medical Center.  

Dr. Kim shares his experience leading the transformation of leading U.S. cancer centers, and how City of Hope is using integrative oncology to reshape the patient experience. They discuss how innovative strategies, such as building a national clinical trial model, will expand patient access and the importance of continually redefining the standard of care - not only for therapeutic solutions but also for prevention and detection interventions. Dr. Kim also opens up about mentorship and his vision for the future of cancer care.

This episode is a must-listen for anyone interested in the next frontier of oncology and what it takes to bring breakthrough treatments to more people.

Follow Us

Presented by City Of Hope

www.CityOfHope.org

]]> Tue, 25 Mar 2025 04:00:00 +0000 stories@amazemedialabs.com (Dr. Monty Pal, Dr. Edward Kim) https://on-the-edge-of-breakthrough.simplecast.com/episodes/breaking-barriers-in-cancer-care-expanding-access-innovation-integrative-medicine-ANuIhqMa In this episode of On the Edge of Breakthrough: Voices of Cancer Research, Dr. Monty Pal speaks with Edward S. Kim, M.D., M.B.A., the physician-in-chief of City of Hope Orange County and Vice Physician-in-Chief of City of Hope National Medical Center.  

Dr. Kim shares his experience leading the transformation of leading U.S. cancer centers, and how City of Hope is using integrative oncology to reshape the patient experience. They discuss how innovative strategies, such as building a national clinical trial model, will expand patient access and the importance of continually redefining the standard of care - not only for therapeutic solutions but also for prevention and detection interventions. Dr. Kim also opens up about mentorship and his vision for the future of cancer care.

This episode is a must-listen for anyone interested in the next frontier of oncology and what it takes to bring breakthrough treatments to more people.

Follow Us

Presented by City Of Hope

www.CityOfHope.org

]]> Breaking Barriers in Cancer Care: Expanding Access, Innovation & Integrative Medicine Dr. Monty Pal, Dr. Edward Kim 00:33:09 Dr. Ed Kim shares insights on why redefining the standard of care is critical for improving patient outcomes, the future of clinical trials, and the role of integrative medicine in oncology. Dr. Ed Kim shares insights on why redefining the standard of care is critical for improving patient outcomes, the future of clinical trials, and the role of integrative medicine in oncology. false full 3 1 c513b568-bacd-492c-9bd0-76f63d3ee1dd The Future of Cancer Surgery: Innovations, AI, and Remote Robotics In this episode of On the Edge of Breakthrough: Voices of Cancer Research, Dr. Monty Pal sits down with Dr. Yuman Fong, an internationally renowned surgical oncologist and Chair of Surgery at City of Hope, to explore the leading-edge innovations shaping the future of surgical oncology.

Dr. Fong shares his incredible journey from studying medieval literature to being one of the first-ever surgeons to conduct surgery in space. They discuss the evolution of oncolytic viruses, the role of AI in cancer surgery, and how remote robotic surgical procedures are transforming patient care worldwide. Dr. Fong also shares  his insights on balancing an intense surgical career with family life, mentorship, and finding passions outside the operating room.

Don’t miss this fascinating conversation about the future of cancer care, where groundbreaking science meets human connection.

Follow Us

Presented by City Of Hope
www.CityOfHope.org

]]> Tue, 11 Mar 2025 04:00:00 +0000 stories@amazemedialabs.com (Dr. Monty Pal, Dr. Yuman Fong) https://on-the-edge-of-breakthrough.simplecast.com/episodes/the-future-of-cancer-surgery-innovations-ai-and-remote-robotics-pOJ_yR_c In this episode of On the Edge of Breakthrough: Voices of Cancer Research, Dr. Monty Pal sits down with Dr. Yuman Fong, an internationally renowned surgical oncologist and Chair of Surgery at City of Hope, to explore the leading-edge innovations shaping the future of surgical oncology.

Dr. Fong shares his incredible journey from studying medieval literature to being one of the first-ever surgeons to conduct surgery in space. They discuss the evolution of oncolytic viruses, the role of AI in cancer surgery, and how remote robotic surgical procedures are transforming patient care worldwide. Dr. Fong also shares  his insights on balancing an intense surgical career with family life, mentorship, and finding passions outside the operating room.

Don’t miss this fascinating conversation about the future of cancer care, where groundbreaking science meets human connection.

Follow Us

Presented by City Of Hope
www.CityOfHope.org

]]> The Future of Cancer Surgery: Innovations, AI, and Remote Robotics Dr. Monty Pal, Dr. Yuman Fong 00:33:01 Dr. Yuman Fong shares insights on AI, robotics, the future of surgical oncology, plus his groundbreaking work in oncolytic viruses and the importance of mentorship. Dr. Yuman Fong shares insights on AI, robotics, the future of surgical oncology, plus his groundbreaking work in oncolytic viruses and the importance of mentorship. false full 2 1 0bfa2088-2eab-401c-8a17-933ab03e0d15 Advancing Cancer Survivorship and Cardio-Oncology In this episode of On the Edge of Breakthrough: Voices of Cancer Research, Dr. Monty Pal is joined by Dr. Saro Armenian, Chair of Pediatric Oncology at City of Hope, to discuss the latest innovative research driving advancements in cancer survivorship and cardio-oncology.

Dr. Armenian shares his compelling journey into oncology, the challenges of addressing long-term treatment effects on patients, and the promising future of CHIP clinics and de-escalation of therapy. Learn how world-leading oncologists are shaping the future of cancer care by bridging leading-edge science with compassionate, patient-centered care at the speed of life.

Follow Us

Presented by City Of Hope

www.CityOfHope.org

]]> Tue, 25 Feb 2025 05:00:00 +0000 stories@amazemedialabs.com (Dr. Monty Pal, Dr. Saro Armenian) https://on-the-edge-of-breakthrough.simplecast.com/episodes/advancing-cancer-survivorship-and-cardio-oncology-5C0FIup7 In this episode of On the Edge of Breakthrough: Voices of Cancer Research, Dr. Monty Pal is joined by Dr. Saro Armenian, Chair of Pediatric Oncology at City of Hope, to discuss the latest innovative research driving advancements in cancer survivorship and cardio-oncology.

Dr. Armenian shares his compelling journey into oncology, the challenges of addressing long-term treatment effects on patients, and the promising future of CHIP clinics and de-escalation of therapy. Learn how world-leading oncologists are shaping the future of cancer care by bridging leading-edge science with compassionate, patient-centered care at the speed of life.

Follow Us

Presented by City Of Hope

www.CityOfHope.org

]]> Advancing Cancer Survivorship and Cardio-Oncology Dr. Monty Pal, Dr. Saro Armenian 00:39:10 Dr. Saro Armenian discusses breakthroughs in cancer survivorship, pediatric oncology and City of Hope’s pioneering work in cardio-oncology. Dr. Saro Armenian discusses breakthroughs in cancer survivorship, pediatric oncology and City of Hope’s pioneering work in cardio-oncology. false full 1 1 53cbe623-c3fb-48c6-a8dc-e46437ccba6f Exploring the Future of Cancer Care Welcome to On the Edge of Breakthrough: Voices of Cancer Research, your gateway to the latest in cancer care innovation. Hosted by Dr. Monty Pal, a medical oncologist and researcher at City of Hope, we’ll bring you inside one of the top 5 cancer research and treatment institutions in the U.S., where innovation and hope go hand-in-hand.

Join Dr. Pal as he sits down with some of the world’s leading cancer experts as they explore some of the most pressing challenges and promising innovations in oncology today.

Whether you're a seasoned healthcare professional, a curious researcher, or simply someone passionate about the fight against cancer, this podcast is your front row seat to hear about the discoveries defining the future of cancer care.

Follow Us

Presented by City Of Hope

www.CityOfHope.org

]]> Tue, 19 Nov 2024 18:35:44 +0000 stories@amazemedialabs.com (Dr. Monty Pal) https://on-the-edge-of-breakthrough.simplecast.com/episodes/exploring-the-future-of-cancer-care-wQ0U_xBy Welcome to On the Edge of Breakthrough: Voices of Cancer Research, your gateway to the latest in cancer care innovation. Hosted by Dr. Monty Pal, a medical oncologist and researcher at City of Hope, we’ll bring you inside one of the top 5 cancer research and treatment institutions in the U.S., where innovation and hope go hand-in-hand.

Join Dr. Pal as he sits down with some of the world’s leading cancer experts as they explore some of the most pressing challenges and promising innovations in oncology today.

Whether you're a seasoned healthcare professional, a curious researcher, or simply someone passionate about the fight against cancer, this podcast is your front row seat to hear about the discoveries defining the future of cancer care.

Follow Us

Presented by City Of Hope

www.CityOfHope.org

]]> Exploring the Future of Cancer Care Dr. Monty Pal 00:00:49 Explore the latest cancer innovations from City of Hope and gain unique insights from world-leading experts who are shaping the future of oncology. Explore the latest cancer innovations from City of Hope and gain unique insights from world-leading experts who are shaping the future of oncology. city of hope false trailer 1