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    <title>Medscape InDiscussion: MASLD</title>
    <description>Listen to Medscape InDiscussion: MASLD, a podcast series where thought leaders and clinical experts share their diverse insights and practical ideas for optimizing patient care. Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/ca8/p04/podcast-masld-s1-ep1-2026a1000aat. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.</description>
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    <pubDate>Thu, 25 Jun 2026 13:33:40 +0000</pubDate>
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      <title>Is Alcohol the Missing Piece in Your MASLD Workup?</title>
      <description><![CDATA[<p>Patients with MASLD often underreport alcohol use and even modest intake can block improvement. Drs VanWagner and Ajmera share practical tools to quantify intake, spot MetALD, and counsel patients effectively.</p>
<p>Relevant disclosures can be found with the episode show notes on Medscape <a href="https://www.medscape.com/ca8/p04/podcast-masld-s1-ep2-2026a1000aau" rel="noopener noreferrer">https://www.medscape.com/ca8/p04/podcast-masld-s1-ep2-2026a1000aau</a>. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.</p>
<p><strong>Resources</strong></p>
<p>Metabolic Dysfunction-Associated Steatotic Liver Disease and Steatohepatitis <a href="https://reference.medscape.com/cc2/p10/global-consensus-recommendations-metabolic-dysfunction-2025a1000iy5#1" rel="noopener noreferrer">https://reference.medscape.com/cc2/p10/global-consensus-recommendations-metabolic-dysfunction-2025a1000iy5#1</a></p>
<p>Is Moderate Alcohol Use in Nonalcoholic Fatty Liver Disease Good or Bad? A Critical Review <a href="https://pubmed.ncbi.nlm.nih.gov/28100008/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/28100008/</a></p>
<p>Practical Guide, Challenges, and Pitfalls in Liver Fibrosis Staging <a href="https://pubmed.ncbi.nlm.nih.gov/37536882/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/37536882/</a></p>
<p>Among Patients With Nonalcoholic Fatty Liver Disease, Modest Alcohol Use Is Associated With Less Improvement in Histologic Steatosis and Steatohepatitis <a href="https://pubmed.ncbi.nlm.nih.gov/29378307/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/29378307/</a></p>
<p>A Multisociety Delphi Consensus Statement on New Fatty Liver Disease Nomenclature <a href="https://pubmed.ncbi.nlm.nih.gov/37363821/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/37363821/</a></p>
<p>Phosphatidylethanol in Steatotic Liver Disease <a href="https://pubmed.ncbi.nlm.nih.gov/40759197/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/40759197/</a></p>
<p>Phosphatidylethanol and Self-Reported Alcohol Intake to Subclassify Individuals at Risk of Steatotic Liver Disease: An Analysis of Data From a Prospective Cohort Study <a href="https://pubmed.ncbi.nlm.nih.gov/40945520/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/40945520/</a></p>
<p>The AUDIT Alcohol Consumption Questions (AUDIT-C): An Effective Brief Screening Test for Problem Drinking. Ambulatory Care Quality Improvement Project (ACQUIP). Alcohol Use Disorders Identification Test <a href="https://pubmed.ncbi.nlm.nih.gov/9738608/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/9738608/</a></p>
<p>Elevated ALT/AST Ratio as a Marker for NAFLD Risk and Severity: Insights From a Cross-Sectional Analysis in the United States <a href="https://pubmed.ncbi.nlm.nih.gov/39253584/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/39253584/</a></p>
<p>Alcohol Use Disorder: A Comparison Between DSM–IV and DSM–5 <a href="https://www.niaaa.nih.gov/publications/brochures-and-fact-sheets/alcohol-use-disorder-comparison-between-dsm" rel="noopener noreferrer">https://www.niaaa.nih.gov/publications/brochures-and-fact-sheets/alcohol-use-disorder-comparison-between-dsm</a></p>
<p>Wilson Disease <a href="https://emedicine.medscape.com/article/183456-overview" rel="noopener noreferrer">https://emedicine.medscape.com/article/183456-overview</a></p><br/> <p>Hosted by Simplecast, an AdsWizz company. See <a href="https://pcm.adswizz.com">pcm.adswizz.com</a> for information about our collection and use of personal data for advertising.</p>]]></description>
      <pubDate>Thu, 25 Jun 2026 13:33:40 +0000</pubDate>
      <author>medscapepodcasts@webmd.net (Dr Lisa B. VanWagner, Dr Veeral H. Ajmera)</author>
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      <content:encoded><![CDATA[<p>Patients with MASLD often underreport alcohol use and even modest intake can block improvement. Drs VanWagner and Ajmera share practical tools to quantify intake, spot MetALD, and counsel patients effectively.</p>
<p>Relevant disclosures can be found with the episode show notes on Medscape <a href="https://www.medscape.com/ca8/p04/podcast-masld-s1-ep2-2026a1000aau" rel="noopener noreferrer">https://www.medscape.com/ca8/p04/podcast-masld-s1-ep2-2026a1000aau</a>. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.</p>
<p><strong>Resources</strong></p>
<p>Metabolic Dysfunction-Associated Steatotic Liver Disease and Steatohepatitis <a href="https://reference.medscape.com/cc2/p10/global-consensus-recommendations-metabolic-dysfunction-2025a1000iy5#1" rel="noopener noreferrer">https://reference.medscape.com/cc2/p10/global-consensus-recommendations-metabolic-dysfunction-2025a1000iy5#1</a></p>
<p>Is Moderate Alcohol Use in Nonalcoholic Fatty Liver Disease Good or Bad? A Critical Review <a href="https://pubmed.ncbi.nlm.nih.gov/28100008/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/28100008/</a></p>
<p>Practical Guide, Challenges, and Pitfalls in Liver Fibrosis Staging <a href="https://pubmed.ncbi.nlm.nih.gov/37536882/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/37536882/</a></p>
<p>Among Patients With Nonalcoholic Fatty Liver Disease, Modest Alcohol Use Is Associated With Less Improvement in Histologic Steatosis and Steatohepatitis <a href="https://pubmed.ncbi.nlm.nih.gov/29378307/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/29378307/</a></p>
<p>A Multisociety Delphi Consensus Statement on New Fatty Liver Disease Nomenclature <a href="https://pubmed.ncbi.nlm.nih.gov/37363821/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/37363821/</a></p>
<p>Phosphatidylethanol in Steatotic Liver Disease <a href="https://pubmed.ncbi.nlm.nih.gov/40759197/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/40759197/</a></p>
<p>Phosphatidylethanol and Self-Reported Alcohol Intake to Subclassify Individuals at Risk of Steatotic Liver Disease: An Analysis of Data From a Prospective Cohort Study <a href="https://pubmed.ncbi.nlm.nih.gov/40945520/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/40945520/</a></p>
<p>The AUDIT Alcohol Consumption Questions (AUDIT-C): An Effective Brief Screening Test for Problem Drinking. Ambulatory Care Quality Improvement Project (ACQUIP). Alcohol Use Disorders Identification Test <a href="https://pubmed.ncbi.nlm.nih.gov/9738608/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/9738608/</a></p>
<p>Elevated ALT/AST Ratio as a Marker for NAFLD Risk and Severity: Insights From a Cross-Sectional Analysis in the United States <a href="https://pubmed.ncbi.nlm.nih.gov/39253584/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/39253584/</a></p>
<p>Alcohol Use Disorder: A Comparison Between DSM–IV and DSM–5 <a href="https://www.niaaa.nih.gov/publications/brochures-and-fact-sheets/alcohol-use-disorder-comparison-between-dsm" rel="noopener noreferrer">https://www.niaaa.nih.gov/publications/brochures-and-fact-sheets/alcohol-use-disorder-comparison-between-dsm</a></p>
<p>Wilson Disease <a href="https://emedicine.medscape.com/article/183456-overview" rel="noopener noreferrer">https://emedicine.medscape.com/article/183456-overview</a></p><br/> <p>Hosted by Simplecast, an AdsWizz company. See <a href="https://pcm.adswizz.com">pcm.adswizz.com</a> for information about our collection and use of personal data for advertising.</p>]]></content:encoded>
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      <description><![CDATA[<p>MASLD is a silent condition and labs may look normal. Drs VanWagner and Shubrook walk through who to screen, how to use FIB-4, and when primary care can manage MASLD without a specialist.</p>
<p>Relevant disclosures can be found with the episode show notes on Medscape <a href="https://www.medscape.com/ca8/p04/podcast-masld-s1-ep1-2026a1000aat" rel="noopener noreferrer">https://www.medscape.com/ca8/p04/podcast-masld-s1-ep1-2026a1000aat</a>. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.</p>
<p><strong>Resources</strong></p>
<p>Metabolic Dysfunction-Associated Steatotic Liver Disease and Steatohepatitis <a href="https://reference.medscape.com/cc2/p10/global-consensus-recommendations-metabolic-dysfunction-2025a1000iy5#1" rel="noopener noreferrer">https://reference.medscape.com/cc2/p10/global-consensus-recommendations-metabolic-dysfunction-2025a1000iy5#1</a></p>
<p>The Global Epidemiology of Nonalcoholic Fatty Liver Disease (NAFLD) and Nonalcoholic Steatohepatitis (NASH): A Systematic Review <a href="https://pubmed.ncbi.nlm.nih.gov/36626630/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/36626630/</a></p>
<p>AASLD Practice Guidance on the Clinical Assessment and Management of Nonalcoholic Fatty Liver Disease <a href="https://pubmed.ncbi.nlm.nih.gov/36727674/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/36727674/</a></p>
<p>Clinical Care Pathway for the Risk Stratification and Management of Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease <a href="https://pubmed.ncbi.nlm.nih.gov/41812830/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/41812830/</a></p>
<p>FIB-4 for Noninvasive Diagnosis of Hepatic Fibrosis <a href="https://reference.medscape.com/calculator/326/fib-4-for-noninvasive-diagnosis-of-hepatic-fibrosis" rel="noopener noreferrer">https://reference.medscape.com/calculator/326/fib-4-for-noninvasive-diagnosis-of-hepatic-fibrosis</a></p>
<p>Noninvasive Liver Fibrosis Assessment in Metabolic Dysfunction-Associated Steatotic Liver Disease <a href="https://pubmed.ncbi.nlm.nih.gov/41640956/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/41640956/</a></p>
<p>NAFLD: Reporting Histologic Findings in Clinical Practice <a href="https://pubmed.ncbi.nlm.nih.gov/33111374/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/33111374/</a></p>
<p>Fibrosis Progression Rate in Biopsy-Proven Nonalcoholic Fatty Liver Disease Among People With Diabetes Versus People Without Diabetes: A Multicenter Study <a href="https://pubmed.ncbi.nlm.nih.gov/37127100/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/37127100/</a></p>
<p>Cause-Specific Mortality in 13,099 Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease in Sweden <a href="https://pubmed.ncbi.nlm.nih.gov/40139508/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/40139508/</a></p>
<p>Liver Function Tests <a href="https://www.ncbi.nlm.nih.gov/books/NBK482489/" rel="noopener noreferrer">https://www.ncbi.nlm.nih.gov/books/NBK482489/</a></p><br/> <p>Hosted by Simplecast, an AdsWizz company. See <a href="https://pcm.adswizz.com">pcm.adswizz.com</a> for information about our collection and use of personal data for advertising.</p>]]></description>
      <pubDate>Thu, 25 Jun 2026 13:33:29 +0000</pubDate>
      <author>medscapepodcasts@webmd.net (Dr Lisa B. VanWagner, Dr Jay H. Shubrook)</author>
      <link>https://www.medscape.com/ca8/p04/podcast-masld-s1-ep1-2026a1000aat</link>
      <content:encoded><![CDATA[<p>MASLD is a silent condition and labs may look normal. Drs VanWagner and Shubrook walk through who to screen, how to use FIB-4, and when primary care can manage MASLD without a specialist.</p>
<p>Relevant disclosures can be found with the episode show notes on Medscape <a href="https://www.medscape.com/ca8/p04/podcast-masld-s1-ep1-2026a1000aat" rel="noopener noreferrer">https://www.medscape.com/ca8/p04/podcast-masld-s1-ep1-2026a1000aat</a>. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.</p>
<p><strong>Resources</strong></p>
<p>Metabolic Dysfunction-Associated Steatotic Liver Disease and Steatohepatitis <a href="https://reference.medscape.com/cc2/p10/global-consensus-recommendations-metabolic-dysfunction-2025a1000iy5#1" rel="noopener noreferrer">https://reference.medscape.com/cc2/p10/global-consensus-recommendations-metabolic-dysfunction-2025a1000iy5#1</a></p>
<p>The Global Epidemiology of Nonalcoholic Fatty Liver Disease (NAFLD) and Nonalcoholic Steatohepatitis (NASH): A Systematic Review <a href="https://pubmed.ncbi.nlm.nih.gov/36626630/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/36626630/</a></p>
<p>AASLD Practice Guidance on the Clinical Assessment and Management of Nonalcoholic Fatty Liver Disease <a href="https://pubmed.ncbi.nlm.nih.gov/36727674/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/36727674/</a></p>
<p>Clinical Care Pathway for the Risk Stratification and Management of Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease <a href="https://pubmed.ncbi.nlm.nih.gov/41812830/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/41812830/</a></p>
<p>FIB-4 for Noninvasive Diagnosis of Hepatic Fibrosis <a href="https://reference.medscape.com/calculator/326/fib-4-for-noninvasive-diagnosis-of-hepatic-fibrosis" rel="noopener noreferrer">https://reference.medscape.com/calculator/326/fib-4-for-noninvasive-diagnosis-of-hepatic-fibrosis</a></p>
<p>Noninvasive Liver Fibrosis Assessment in Metabolic Dysfunction-Associated Steatotic Liver Disease <a href="https://pubmed.ncbi.nlm.nih.gov/41640956/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/41640956/</a></p>
<p>NAFLD: Reporting Histologic Findings in Clinical Practice <a href="https://pubmed.ncbi.nlm.nih.gov/33111374/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/33111374/</a></p>
<p>Fibrosis Progression Rate in Biopsy-Proven Nonalcoholic Fatty Liver Disease Among People With Diabetes Versus People Without Diabetes: A Multicenter Study <a href="https://pubmed.ncbi.nlm.nih.gov/37127100/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/37127100/</a></p>
<p>Cause-Specific Mortality in 13,099 Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease in Sweden <a href="https://pubmed.ncbi.nlm.nih.gov/40139508/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/40139508/</a></p>
<p>Liver Function Tests <a href="https://www.ncbi.nlm.nih.gov/books/NBK482489/" rel="noopener noreferrer">https://www.ncbi.nlm.nih.gov/books/NBK482489/</a></p><br/> <p>Hosted by Simplecast, an AdsWizz company. See <a href="https://pcm.adswizz.com">pcm.adswizz.com</a> for information about our collection and use of personal data for advertising.</p>]]></content:encoded>
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