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    <title>Medscape InDiscussion: Gout</title>
    <description>Listen to Medscape InDiscussion: Gout, a podcast series where thought leaders and clinical experts share their diverse insights and practical ideas for optimizing patient care. Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/ca8/p04/podcast-gout-s1-ep1-2026a1000qeh. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.</description>
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    <pubDate>Wed, 2 Sep 2026 13:43:31 +0000</pubDate>
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      <title>Seeing Gout Clearly: Advances in Diagnosis and Imaging</title>
      <description><![CDATA[<p>Drs Kenneth Saag and Nicola Dalbeth explore how crystal analysis and imaging advances can sharpen gout diagnosis and guide patient care.</p>
<p>Relevant disclosures can be found with the episode show notes on Medscape <a href="https://www.medscape.com/ca8/p04/podcast-gout-s1-ep2-2026a1000qej" rel="noopener noreferrer">https://www.medscape.com/ca8/p04/podcast-gout-s1-ep2-2026a1000qej</a>. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.</p>
<p><strong>Resources</strong></p>
<p>Gout and Pseudogout <a href="https://emedicine.medscape.com/article/329958-overview" rel="noopener noreferrer">https://emedicine.medscape.com/article/329958-overview</a></p>
<p>2015 Gout Classification Criteria: An American College of Rheumatology/European League Against Rheumatism Collaborative Initiative <a href="https://pubmed.ncbi.nlm.nih.gov/26352873/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/26352873/</a></p>
<p>Clinical Features and Recurrent Attack in Gout Patients According to Serum Urate Levels During an Acute Attack <a href="https://pubmed.ncbi.nlm.nih.gov/30685959/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/30685959/</a></p>
<p>Gout on the Acute Medical Take <a href="https://pubmed.ncbi.nlm.nih.gov/40436276/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/40436276/</a></p>
<p>Psoriatic Arthritis <a href="https://emedicine.medscape.com/article/2196539-overview" rel="noopener noreferrer">https://emedicine.medscape.com/article/2196539-overview</a></p>
<p>Rheumatoid Arthritis (RA) <a href="https://emedicine.medscape.com/article/331715-overview" rel="noopener noreferrer">https://emedicine.medscape.com/article/331715-overview</a></p>
<p>Synovial Fluid Analysis: Relevance for Daily Clinical Practice <a href="https://pubmed.ncbi.nlm.nih.gov/37429800/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/37429800/</a></p>
<p>Advanced Imaging Techniques in Crystal Arthritis <a href="https://pubmed.ncbi.nlm.nih.gov/39906218/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/39906218/</a></p>
<p>Ultrasound Features in Gout: An Overview <a href="https://pubmed.ncbi.nlm.nih.gov/39189200/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/39189200/</a></p>
<p>Dynamic Assessment of the Double Contour Sign by Ultrasonography Helps to Distinguish Between Gout and Calcium Pyrophosphate Deposition Disease <a href="https://pubmed.ncbi.nlm.nih.gov/36927850/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/36927850/</a></p>
<p>Test Characteristics of Raman Spectroscopy Integrated With Polarized Light Microscopy for the Diagnosis of Acute Gouty Arthritis <a href="https://pubmed.ncbi.nlm.nih.gov/37442334/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/37442334/</a></p>
<p>Dual-energy CT Applications in Musculoskeletal Disorders <a href="https://pubmed.ncbi.nlm.nih.gov/38291893/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/38291893/</a></p><br/> <p>Hosted by Simplecast, an AdsWizz company. See <a href="https://pcm.adswizz.com">pcm.adswizz.com</a> for information about our collection and use of personal data for advertising.</p>]]></description>
      <pubDate>Wed, 2 Sep 2026 13:43:31 +0000</pubDate>
      <author>medscapepodcasts@webmd.net (Dr Kenneth Saag, Dr Nicola Dalbeth)</author>
      <link>https://www.medscape.com/ca8/p04/podcast-gout-s1-ep2-2026a1000qej</link>
      <content:encoded><![CDATA[<p>Drs Kenneth Saag and Nicola Dalbeth explore how crystal analysis and imaging advances can sharpen gout diagnosis and guide patient care.</p>
<p>Relevant disclosures can be found with the episode show notes on Medscape <a href="https://www.medscape.com/ca8/p04/podcast-gout-s1-ep2-2026a1000qej" rel="noopener noreferrer">https://www.medscape.com/ca8/p04/podcast-gout-s1-ep2-2026a1000qej</a>. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.</p>
<p><strong>Resources</strong></p>
<p>Gout and Pseudogout <a href="https://emedicine.medscape.com/article/329958-overview" rel="noopener noreferrer">https://emedicine.medscape.com/article/329958-overview</a></p>
<p>2015 Gout Classification Criteria: An American College of Rheumatology/European League Against Rheumatism Collaborative Initiative <a href="https://pubmed.ncbi.nlm.nih.gov/26352873/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/26352873/</a></p>
<p>Clinical Features and Recurrent Attack in Gout Patients According to Serum Urate Levels During an Acute Attack <a href="https://pubmed.ncbi.nlm.nih.gov/30685959/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/30685959/</a></p>
<p>Gout on the Acute Medical Take <a href="https://pubmed.ncbi.nlm.nih.gov/40436276/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/40436276/</a></p>
<p>Psoriatic Arthritis <a href="https://emedicine.medscape.com/article/2196539-overview" rel="noopener noreferrer">https://emedicine.medscape.com/article/2196539-overview</a></p>
<p>Rheumatoid Arthritis (RA) <a href="https://emedicine.medscape.com/article/331715-overview" rel="noopener noreferrer">https://emedicine.medscape.com/article/331715-overview</a></p>
<p>Synovial Fluid Analysis: Relevance for Daily Clinical Practice <a href="https://pubmed.ncbi.nlm.nih.gov/37429800/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/37429800/</a></p>
<p>Advanced Imaging Techniques in Crystal Arthritis <a href="https://pubmed.ncbi.nlm.nih.gov/39906218/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/39906218/</a></p>
<p>Ultrasound Features in Gout: An Overview <a href="https://pubmed.ncbi.nlm.nih.gov/39189200/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/39189200/</a></p>
<p>Dynamic Assessment of the Double Contour Sign by Ultrasonography Helps to Distinguish Between Gout and Calcium Pyrophosphate Deposition Disease <a href="https://pubmed.ncbi.nlm.nih.gov/36927850/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/36927850/</a></p>
<p>Test Characteristics of Raman Spectroscopy Integrated With Polarized Light Microscopy for the Diagnosis of Acute Gouty Arthritis <a href="https://pubmed.ncbi.nlm.nih.gov/37442334/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/37442334/</a></p>
<p>Dual-energy CT Applications in Musculoskeletal Disorders <a href="https://pubmed.ncbi.nlm.nih.gov/38291893/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/38291893/</a></p><br/> <p>Hosted by Simplecast, an AdsWizz company. See <a href="https://pcm.adswizz.com">pcm.adswizz.com</a> for information about our collection and use of personal data for advertising.</p>]]></content:encoded>
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      <title>Gout and Comorbidities: A Two-Way Relationship</title>
      <description><![CDATA[<p>Drs Ken Saag and Michael Pillinger explore the chicken-or-egg question connecting gout with cardiovascular, kidney, and metabolic conditions.</p>
<p>Relevant disclosures can be found with the episode show notes on Medscape <a href="https://www.medscape.com/ca8/p04/podcast-gout-s1-ep1-2026a1000qeh" rel="noopener noreferrer">https://www.medscape.com/ca8/p04/podcast-gout-s1-ep1-2026a1000qeh</a>. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.</p>
<p><strong>Resources</strong></p>
<p>Gout and Pseudogout <a href="https://emedicine.medscape.com/article/329958-overview" rel="noopener noreferrer">https://emedicine.medscape.com/article/329958-overview</a></p>
<p>Gout: Global Epidemiology, Risk Factors, Comorbidities and Complications: A Narrative Review <a href="https://pubmed.ncbi.nlm.nih.gov/39702222/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/39702222/</a></p>
<p>The Fifth Element: Is Vascular Dysfunction an Intrinsic Feature of Gout? <a href="https://pubmed.ncbi.nlm.nih.gov/40021439/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/40021439/</a></p>
<p>Hyperuricemia Induces a Primary Renal Arteriolopathy in Rats by a Blood Pressure-Independent Mechanism <a href="https://pubmed.ncbi.nlm.nih.gov/11997315/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/11997315/</a></p>
<p>The Environment and Disease: Association or Causation? <a href="https://pubmed.ncbi.nlm.nih.gov/14283879/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/14283879/</a></p>
<p>Effect of Allopurinol on Blood Pressure of Adolescents With Newly Diagnosed Essential Hypertension: A Randomized Trial <a href="https://pubmed.ncbi.nlm.nih.gov/18728266/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/18728266/</a></p>
<p>Expert Consensus and Evidence-Based Recommendations for the Assessment of Flow-Mediated Dilation in Humans <a href="https://pubmed.ncbi.nlm.nih.gov/31211361/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/31211361/</a></p>
<p>Reading Mendelian Randomisation Studies: A Guide, Glossary, and Checklist for Clinicians <a href="https://pubmed.ncbi.nlm.nih.gov/30002074/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/30002074/</a></p>
<p>Effects of Allopurinol on the Progression of Chronic Kidney Disease <a href="https://pubmed.ncbi.nlm.nih.gov/32579811/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/32579811/</a></p>
<p>Pegloticase Treatment Significantly Decreases Blood Pressure in Patients With Chronic Gout <a href="https://pubmed.ncbi.nlm.nih.gov/31079535/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/31079535/</a></p>
<p>Treat-to-Target Urate-Lowering Treatment and Cardiovascular Outcomes in Patients With Gout <a href="https://pubmed.ncbi.nlm.nih.gov/41587055/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/41587055/</a></p>
<p>Risk of Venous Thromboembolism With Gout Flares <a href="https://pubmed.ncbi.nlm.nih.gov/36808284/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/36808284/</a></p>
<p>Cardiovascular Events in Patients With Gout Initiating Urate-Lowering Therapy With or Without Colchicine for Flare Prophylaxis: A Retrospective New-User Cohort Study Using Linked Primary Care, Hospitalisation, and Mortality Data <a href="https://pubmed.ncbi.nlm.nih.gov/39708831/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/39708831/</a></p>
<p>Comparative Cardiovascular Safety of Nonsteroidal Anti-Inflammatory Drug Versus Colchicine Use When Initiating Urate-Lowering Therapy Among Patients With Gout: Target Trial Emulations <a href="https://pubmed.ncbi.nlm.nih.gov/40415645/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/40415645/</a></p>
<p>Uric Acid as a Risk Factor for Chronic Kidney Disease and Cardiovascular Disease - Japanese Guideline on the Management of Asymptomatic Hyperuricemia <a href="https://pubmed.ncbi.nlm.nih.gov/33342914/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/33342914/</a></p><br/> <p>Hosted by Simplecast, an AdsWizz company. See <a href="https://pcm.adswizz.com">pcm.adswizz.com</a> for information about our collection and use of personal data for advertising.</p>]]></description>
      <pubDate>Wed, 2 Sep 2026 13:42:22 +0000</pubDate>
      <author>medscapepodcasts@webmd.net (Dr Kenneth Saag, Dr Michael H. Pillinger)</author>
      <link>https://www.medscape.com/ca8/p04/podcast-gout-s1-ep1-2026a1000qeh</link>
      <content:encoded><![CDATA[<p>Drs Ken Saag and Michael Pillinger explore the chicken-or-egg question connecting gout with cardiovascular, kidney, and metabolic conditions.</p>
<p>Relevant disclosures can be found with the episode show notes on Medscape <a href="https://www.medscape.com/ca8/p04/podcast-gout-s1-ep1-2026a1000qeh" rel="noopener noreferrer">https://www.medscape.com/ca8/p04/podcast-gout-s1-ep1-2026a1000qeh</a>. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.</p>
<p><strong>Resources</strong></p>
<p>Gout and Pseudogout <a href="https://emedicine.medscape.com/article/329958-overview" rel="noopener noreferrer">https://emedicine.medscape.com/article/329958-overview</a></p>
<p>Gout: Global Epidemiology, Risk Factors, Comorbidities and Complications: A Narrative Review <a href="https://pubmed.ncbi.nlm.nih.gov/39702222/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/39702222/</a></p>
<p>The Fifth Element: Is Vascular Dysfunction an Intrinsic Feature of Gout? <a href="https://pubmed.ncbi.nlm.nih.gov/40021439/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/40021439/</a></p>
<p>Hyperuricemia Induces a Primary Renal Arteriolopathy in Rats by a Blood Pressure-Independent Mechanism <a href="https://pubmed.ncbi.nlm.nih.gov/11997315/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/11997315/</a></p>
<p>The Environment and Disease: Association or Causation? <a href="https://pubmed.ncbi.nlm.nih.gov/14283879/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/14283879/</a></p>
<p>Effect of Allopurinol on Blood Pressure of Adolescents With Newly Diagnosed Essential Hypertension: A Randomized Trial <a href="https://pubmed.ncbi.nlm.nih.gov/18728266/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/18728266/</a></p>
<p>Expert Consensus and Evidence-Based Recommendations for the Assessment of Flow-Mediated Dilation in Humans <a href="https://pubmed.ncbi.nlm.nih.gov/31211361/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/31211361/</a></p>
<p>Reading Mendelian Randomisation Studies: A Guide, Glossary, and Checklist for Clinicians <a href="https://pubmed.ncbi.nlm.nih.gov/30002074/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/30002074/</a></p>
<p>Effects of Allopurinol on the Progression of Chronic Kidney Disease <a href="https://pubmed.ncbi.nlm.nih.gov/32579811/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/32579811/</a></p>
<p>Pegloticase Treatment Significantly Decreases Blood Pressure in Patients With Chronic Gout <a href="https://pubmed.ncbi.nlm.nih.gov/31079535/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/31079535/</a></p>
<p>Treat-to-Target Urate-Lowering Treatment and Cardiovascular Outcomes in Patients With Gout <a href="https://pubmed.ncbi.nlm.nih.gov/41587055/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/41587055/</a></p>
<p>Risk of Venous Thromboembolism With Gout Flares <a href="https://pubmed.ncbi.nlm.nih.gov/36808284/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/36808284/</a></p>
<p>Cardiovascular Events in Patients With Gout Initiating Urate-Lowering Therapy With or Without Colchicine for Flare Prophylaxis: A Retrospective New-User Cohort Study Using Linked Primary Care, Hospitalisation, and Mortality Data <a href="https://pubmed.ncbi.nlm.nih.gov/39708831/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/39708831/</a></p>
<p>Comparative Cardiovascular Safety of Nonsteroidal Anti-Inflammatory Drug Versus Colchicine Use When Initiating Urate-Lowering Therapy Among Patients With Gout: Target Trial Emulations <a href="https://pubmed.ncbi.nlm.nih.gov/40415645/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/40415645/</a></p>
<p>Uric Acid as a Risk Factor for Chronic Kidney Disease and Cardiovascular Disease - Japanese Guideline on the Management of Asymptomatic Hyperuricemia <a href="https://pubmed.ncbi.nlm.nih.gov/33342914/" rel="noopener noreferrer">https://pubmed.ncbi.nlm.nih.gov/33342914/</a></p><br/> <p>Hosted by Simplecast, an AdsWizz company. See <a href="https://pcm.adswizz.com">pcm.adswizz.com</a> for information about our collection and use of personal data for advertising.</p>]]></content:encoded>
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