Decera Clinical Education Infectious Disease Podcast

Real-world Data From CROI: What’s New in HIV Care for Treatment-Experienced People

Mon, 23 Mar 2026 19:15:44 +0000

“Good enough” is no longer good enough when caring for treatment-experienced people with HIV. Tune in to find out what’s new in management of multidrug-resistant HIV and dig into the latest data from CROI 2026. Topics covered include:

Real-world experiences with LEN in the United States and Europe for management of multidrug-resistant HIV

Pharmacokinetic profiles of combined LA CAB + LEN
Ibalizumab for multidrug-resistant HIV
Long-term 7-year outcomes for heavily treatment–experienced people living with HIV and 4-class drug resistance

To download the accompanying slides, please visit the program page:
https://bit.ly/4pEenZC

Get access to all of our new podcasts by subscribing to the Decera Clinical Education Infectious Disease Podcast on Apple Podcasts, YouTube Music, or Spotify.

Presenters:

Onyema Ogbuagu, MD, FACP, FIDSA
Professor of Medicine and Pharmacology
Director, Yale Antivirals and Vaccines Research Program
Yale School of Medicine
New Haven, Connecticut

Charlotte-Paige Rolle, MD, MPH
Director of Research Operations
Orlando Immunology Center
Adjunct Assistant Professor of Global Health
Emory University Rollins School of Public Health
Atlanta, Georgia

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HIV Update Podcast: Independent Conference Coverage of CROI 2026

support@deceraclinical.com (Monica Gandhi MD MPH, Jean-Michel Molina MD) — Fri, 13 Mar 2026 13:14:09 +0000

Tune into this podcast, featuring audio from a live conference coverage webinar, to learn from global experts, Monica Gandhi, MD, MPH, and Jean-Michel Molina, MD, as they summarize and discuss the latest updates on HIV treatment and prevention from CROI 2026. Topics covered include:

Emerging HIV treatments
Advances in HIV prevention
Investigational agents for HIV prevention
Early-phase investigational HIV treatments

For more coverage of CROI 2026, and to follow along with the downloadable slides, visit the program page:
https://bit.ly/4bmS062

Get access to all of our new podcasts by subscribing to the Decera Clinical Education Infectious Disease Podcast on Apple Podcasts, YouTube Music, or Spotify.

Presenters:

Monica Gandhi, MD, MPH
Professor of Medicine and Associate Chief
Division of HIV, Infectious Diseases, and Global Medicine
Director, UCSF Center for AIDS Research (CFAR)
Director of HIV Special Program
"Ward 86" HIV Clinic
San Francisco General Hospital
San Francisco, California

Jean-Michel Molina, MD
Professor of Medicine
Saint-Louis and Lariboisire Hospitals
Université Paris Cité
Paris, France

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Treatment of Refractory/Resistant CMV in HCT Recipients: Optimizing Transplant Outcomes Through Contemporary CMV Management

Mon, 9 Mar 2026 19:42:47 +0000

Cytomegalovirus (CMV) infection is one of the most significant infectious complications after hematopoietic cell transplant (HCT), but there have been major advances in CMV management to date. In this podcast, featuring curated audio from a live satellite symposium, experts Roy F. Chemaly, MD, MPH, FIDSA, FACP, FESCMID, and Marcus Pereira, MD, MPH, FAST, discuss considerations for CMV treatment in HCT recipients and examine treatment options for refractory/resistant CMV.

Topics include:

Considerations for CMV management in HCT recipients
New definitions of refractory and resistant CMV
Risk factors for refractory and resistant CMV infections
Identifying drug-resistant CMV
Treatment options for refractory/resistant CMV

To view the full educational program and download the accompanying slides, visit our website:
https://bit.ly/4lfrDTT

Presenters:

Roy F. Chemaly, MD, MPH, FIDSA, FACP, FESCMID
Professor and Chair
G.P. Bodey, Sr. Distinguished Professorship in Infectious Diseases
President, The International Immunocompromised Host Society (ICHS)
Director, Clinical Virology Research
Department of ID/IC/EH
UT MD Anderson Cancer Center
Houston, Texas

Marcus Pereira, MD, MPH, FAST
Associate Professor of Medicine
Director of Clinical Services, Division of Infectious Diseases
Medical Director, Transplant Infectious Disease Program
Columbia University Irving Medical Center
New York, New York

Get access to all of our new podcasts by subscribing to the Decera Clinical Education Infectious Disease Podcast on Apple Podcasts, YouTube Music, or Spotify.

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Managing CMV Risk in HCT Recipients: Optimizing Transplant Outcomes Through Contemporary CMV Management

Mon, 9 Mar 2026 19:30:44 +0000

Cytomegalovirus (CMV) infection is one of the most significant infectious complications after hematopoietic cell transplant (HCT). In this podcast, featuring curated audio from a live satellite symposium, experts Roy F. Chemaly, MD, MPH, FIDSA, FACP, FESCMID and Marcus Pereira, MD, MPH, FAST, discuss the burden of CMV in HCT recipients and explore strategies effectively identify and monitor high-risk patients. Topics include:

Epidemiology of CMV among HCT recipients
Direct and indirect effects of CMV after HCT
Dynamics of risk factors for CMV infection
Strategies for prevention of CMV infection

To view the full educational program and download the accompanying slides, visit our website:
https://bit.ly/4lfrDTT

Presenters:

Get access to all of our new podcasts by subscribing to the Decera Clinical Education Infectious Disease Podcast on Apple Podcasts, YouTube Music, or Spotify.

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Shingles Solutions Podcast: Strategies for Improving Vaccine Uptake and Series Completion

Tue, 17 Feb 2026 19:39:50 +0000

In this podcast, experts Jacinda (JAM) Abdul-Mutakabbir, PharmD, MPH; Ruth Carrico, PhD, DNP, FNP-C, FAAN; and Dalilah Restrepo, MD, discuss improving shingles vaccine uptake. Topics covered include:

The Burden of Shingles
Care Coordination Between Primary and Specialty Care
Promoting Shingles Vaccine Series Completion
Addressing Disparities in Shingles Vaccine Access and Uptake

Presenters:

Jacinda (JAM) Abdul-Mutakabbir, PharmD, MPH
Associate Professor of Clinical Pharmacy
University of California, San Diego
Department of Pharmacy Practice and Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences
Division of the Black Diaspora and African American Studies
La Jolla, California

Ruth Carrico, PhD, DNP, FNP-C, FAAN
Senior Partner
Carrico & Ramirez PLLC
Professor, Adjunct
Division of Infectious Diseases
University of Louisville School of Medicine
Louisville, Kentucky

Dalilah Restrepo, MD
Infectious Diseases Specialist
University of California, Irvine
Los Alamitos Hospital
Orange County, California

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Setting Our Sights on Symptom Management: Raising the Bar in PBC Management Podcast

Tue, 3 Feb 2026 14:58:01 +0000

Historically, key symptoms of primary biliary cholangitis (PBC), such as pruritus and fatigue, have been understudied and undertreated. Listen now to learn how symptom management should be considered independently of PBC management, and how new therapeutic agents can help.

Topics covered include:

Mechanisms of pruritus and fatigue in PBC
Nonpharmacologic treatment options
An overview of clinical trial data supporting second-line agents for symptom management:
Bezafibrate
Elafibranor
Seladelpar
Investigational agents:
Volixibat
Linerixibat
Setanaxib

This episode is the third of 3 recap podcasts, featuring audio from our live satellite symposium, Raising the Bar: Innovations in PBC Care. For the full on-demand webcast of this satellite symposium, and to download the accompanying slides, visit the program page for this episode:
https://bit.ly/44ZJ5os

Presenters:
Christopher L. Bowlus, MD
Lena Valente Professor and Chief
Division of Gastroenterology and Hepatology
School of Medicine
University of California Davis
Sacramento, California

Aparna Goel, MD
Clinical Associate Professor of Medicine
Division of Gastroenterology and Hepatology
Stanford University
Palo Alto, California

Aliya F. Gulamhusein, MD,
MPH, FRCPC
Professorship in PSC Research
Clinician Investigator, Toronto General Hospital
Assistant Professor, University of Toronto
Division of Gastroenterology and Hepatology
University Health Network
Toronto, Canada

Get access to all of our new episodes by subscribing to the Decera Clinical Education Medical Specialties Podcast on Apple Podcasts, YouTube Music, or Spotify.

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Second-line Agents for Achieving Treatment Goals: Raising the Bar in PBC Management Podcast

Tue, 3 Feb 2026 14:56:47 +0000

New therapeutic agents for second-line treatment are raising the bar for primary biliary cholangitis (PBC) management. Listen now to learn how to incorporate these new agents into clinical practice and how these agents will impact attainment of treatment goals.

Topics covered include:

Available agents for second-line treatment of PBC
An overview of clinical trial data supporting second-line agents:
Obeticholic acid (OCA)
Bezafibrate
Elafibranor
Seladelpar

This episode is the second of 3 recap podcasts, featuring audio from our live satellite symposium, Raising the Bar: Innovations in PBC Care. For the full on-demand webcast of this satellite symposium, and to download the accompanying slides, visit the program page for this episode: https://bit.ly/48MEc3r

Presenters:

Christopher L. Bowlus, MD
Lena Valente Professor and Chief
Division of Gastroenterology and Hepatology
School of Medicine
University of California Davis
Sacramento, California

Aparna Goel, MD
Clinical Associate Professor of Medicine
Division of Gastroenterology and Hepatology
Stanford University
Palo Alto, California

Aliya F. Gulamhusein, MD, MPH, FRCPC
Professorship in PSC Research
Clinician Investigator, Toronto General Hospital
Assistant Professor, University of Toronto
Division of Gastroenterology and Hepatology
University Health Network
Toronto, Canada

Get access to all of our new episodes by subscribing to the Decera Clinical Education Medical Specialties Podcast on Apple Podcasts, YouTube Music, or Spotify.

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Defining Our Treatment Goals: Raising the Bar in PBC Management Podcast

Tue, 3 Feb 2026 14:54:57 +0000

Advancements in our understanding of primary biliary cholangitis (PBC) and new therapeutic agents have reshaped the care landscape of PBC. Listen now to learn how these developments are helping to redefine and elevate treatment goals. Topics covered include:

How and when to assess treatment response
Risk factors in PBC
Biochemical treatment response and fibrosis stage as predictors of transplant-free survival
Dynamics of liver stiffness measurements and clinical outcomes in PBC
The importance of bilirubin and alkaline phosphatase normalization

This episode is the first of 3 recap podcasts, featuring audio from our live satellite symposium, Raising the Bar: Innovations in PBC Care. For the full on-demand webcast of this satellite symposium, and to download the accompanying slides, visit the program page for this episode: https://bit.ly/44ZJ5os

Presenters:

Christopher L. Bowlus, MD
Lena Valente Professor and Chief
Division of Gastroenterology and Hepatology
School of Medicine
University of California Davis
Sacramento, California

Aparna Goel, MD
Clinical Associate Professor of Medicine
Division of Gastroenterology and Hepatology
Stanford University
Palo Alto, California

Get access to all of our new episodes by subscribing to the Decera Clinical Education Medical Specialties Podcast on Apple Podcasts, YouTube Music, or Spotify. 

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Keeping Up With New Developments in PBC

support@deceraclinical.com (Christopher L. Bowlus MD, Sonal Kumar MD MPH) — Mon, 2 Feb 2026 22:04:38 +0000

Tune in to listen as expert faculty, Dr Christopher L. Bowlus and Dr Sonal Kumar, discuss recent developments in treating primary biliary cholangitis (PBC) with new and emerging agents, as well as strategies to integrate these advances into clinical practice.

Topics covered include:

Methods of Assessing PBC Disease Progression
Newer Agents for Second-line Treatment of PBC
Prioritizing Symptom Management and Quality of Life With PBC Treatment

Presenters:

Christopher L. Bowlus, MD
Lena Valenta Professor and Chief
Division of Gastroenterology and Hepatology
School of Medicine
University of California Davis
Sacramento, California

Sonal Kumar, MD, MPH
Assistant Professor of Medicine
Division of Gastroenterology and Hepatology
Weill Cornell Medical College
New York, New York

Link to full program:
https://bit.ly/43nHx6U

Get access to all of our new podcasts by subscribing to the Decera Clinical Education Infectious Disease Podcast on Apple Podcasts, YouTube Music, or Spotify.

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Key PBC Studies From AASLD 2025 Podcast

support@deceraclinical.com (Decera Clinical Education) — Mon, 2 Feb 2026 21:16:06 +0000

Listen in as Nancy Reau, MD, reviews key highlights of the most impactful primary biliary cholangitis (PBC) research and gain insights on how to apply these new advances to clinical practice.

Topics covered include:

Treatment Goals
Long-term Data With PPAR Agonists
Investigational Therapies for Pruritus

Presenter:

Nancy Reau, MD
Professor of Medicine
Richard B. Capps Chair of Hepatology
Chief, Section of Hepatology
Associate Director, Solid Organ Transplantation
Rush University Medical Center
Chicago, Illinois

To download the accompanying slides, visit the program page for this episode:
https://bit.ly/4b2d6YD

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Patient Perspectives on New Developments in PBC: Individualizing Patient Care Podcast

support@deceraclinical.com (Maria G. Morais RN) — Mon, 2 Feb 2026 21:00:37 +0000

Recent advances in primary biliary cholangitis (PBC) care have resulted in a new focus on personalized care and symptom management. Tune in to learn from patient advocate, Maria G. Morais, RN, how you can integrate patient insights and priorities into treatment plans for PBC. Topics covered include:

The Canadian PBC Society Survey: Comorbidities and Treatment Goals
Defining and Achieving Goal-Driven Care for PBC
Recent Advances in PBC Management
Newer Agents for Second-line Treatment of PBC

Presenters:

Maria G. Morais, RN
PBC Transplant Patient
VP Patient Advocacy
Canadian PBC Society
Toronto, Canada

Link to full program:
https://bit.ly/44ySoL3

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, YouTube Music, or Spotify. 

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The Pediatric Influenza Vaccine Playbook Podcast: Proven Paths to Prevention

Thu, 15 Jan 2026 21:10:17 +0000

Listen to this podcast featuring highlights from our expert roundtable discussion to learn about the most pressing issues in pediatric influenza vaccines, including current vaccine technologies, recent vaccine uptake and epidemiologic trends, and how to discuss the vast benefits of timely vaccination in pediatric patients with their parents and caregivers. Topics covered include:

Groups at High Risk for Complications
Guideline Recommendations for Influenza Vaccination
Available Seasonal Flu Vaccine Formulations and Their Characteristics
Practical Considerations for Selecting Pediatric Influenza Vaccines
Uptake of Influenza Vaccines in Children: Reversing the Trends

Presenters:

Ravi Jhaveri, MD, FIDSA, FPIDS, FAAP
Division Head
Pediatric Infectious Diseases
Ann & Robert H. Lurie Children’s Hospital of Chicago
Professor of Pediatrics
Northwestern University Feinberg School of Medicine
Chicago, Illinois

Tina Q. Tan, MD, FAAP, FIDSA, FPIDS
Professor of Pediatrics
Feinberg School of Medicine of Northwestern University
Pediatric Infectious Diseases Attending
Medical Director, International Adoptee Clinic
President, Lurie Medical/Dental Staff
Ann & Robert H. Lurie Children’s Hospital of Chicago
Chicago, Illinois

Jennifer M. Walsh, DNP, CPNP-PC, CNE
Certified Pediatric Nurse Practitioner, Primary Care
Assistant Professor
George Washington University
School of Nursing
Washington, DC

Link to full program:
https://bit.ly/45UVzy6

Get access to all of our new episodes by subscribing to the Decera Clinical Education Infectious Diseases Podcast on Apple Podcasts, YouTube Music, or Spotify.

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Beyond Viral Suppression: What’s New in HIV Care for Treatment-Experienced People

Thu, 15 Jan 2026 17:23:58 +0000

Tune in as Princy N. Kumar, MD, MACP, FRCP, and Charlotte-Paige Rolle, MD, MPH discuss the latest in immune recovery, chronic inflammation, and more in the management of treatment-experienced people living with HIV.

Topics covered include:

Immunologic nonresponse
Theories around soluble gp120 and antibody-dependent cellular cytotoxicity
Latest data from BRIGHTE, RECOVER, and more
Future Directions

Presenters:

Princy N. Kumar, MD, MACP, FRCP
Professor of Medicine and Microbiology
Chief, Division of Infectious Diseases and Tropical Medicine
Vice Dean for Student Affairs
Georgetown University School of Medicine
Washington, DC

Link to full program:
https://bit.ly/4pEenZC

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Decera Clinical Education Independent Conference Coverage of IDWeek and EACS 2025: HIV Update Podcast

support@deceraclinical.com (Karine Lacombe MD PhD, Chloe Orkin MBChB FRCP MD) — Thu, 18 Dec 2025 21:36:04 +0000

Tune into this podcast to revisit discussions led by global experts, Karine Lacombe, MD, PhD, and Chloe Orkin, MBChB, FRCP, MD, featuring the latest updates on HIV treatment and prevention from the 2025 IDWeek and EACS conferences.

Topics covered include:

Real-world safety and efficacy of long-acting ART
ART switch: preferences, treatment satisfaction, changes in weight and metabolic parameters, and HBV reactivation risk
Investigational therapies
Updates on long-acting PrEP: persistence, use in people with substance use disorder, and coadministration with gender-affirming hormone therapy
HIV and STI screening with PrEP
STI prevention

To download the accompanying slides, visit the program page for this episode:
https://bit.ly/3MGvegM

Presenters:
Karine Lacombe, MD, PhD
Professor of Medicine
Sorbonne University
Head of Infectious Diseases Unit
St Antoine Hospital, AP-HP
Paris, France

Chloe Orkin, MBChB, FRCP, MD
Professor of Infection and Inequities
Dean for Healthcare Transformation
Queen Mary University of London
Faculty of Medicine and Dentistry
Honorary Consultant Physician
Barts Health NHS Trust
London, United Kingdom

Get access to all of our new episodes by subscribing to the Decera Clinical Education Infectious Diseases Podcast on Apple Podcasts, YouTube Music, or Spotify.

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RSV Revealed Podcast: The Role of Diagnostic Testing in Advancing Clinical Care

Mon, 15 Dec 2025 21:34:02 +0000

In this podcast, featuring audio from an expert roundtable video module, listen as 3 multidisciplinary faculty, Tracey Q. Davidoff, MD, FCUCM; Carina Marquez, MD, MPH; and Jeffrey D. Whitman, MD, MS, discuss the benefits of diagnosing respiratory syncytial virus (RSV) and optimal testing strategies. Topics covered include:

The annual burden of RSV and the benefits of diagnosis
Whom to test and what diagnostic techniques to use
Logistical considerations for implementation
Potential benefits of RSV testing

For the full video module and to download the accompanying slides, visit the program page for this episode:
https://bit.ly/3MrXTpI

Presenters:
Tracey Q. Davidoff, MD, FCUCM
Attending Physician
Baycare Urgent Care
Assistant Professor, Family Medicine
Florida State University College of Medicine
Tallahassee, Florida

Carina Marquez, MD, MPH
Associate Professor of Medicine
Division of HIV, Infectious Diseases and Global Medicine
University of California, San Francisco
San Francisco, California

Jeffrey D. Whitman, MD, MS
Co-Director of Clinical Microbiology
Associate Professor
Department of Laboratory Medicine
University of California, San Francisco
San Francisco, California

Get access to all of our new podcasts by subscribing to the Decera Clinical Education Infectious Disease Podcast on Apple Podcasts, YouTube Music, or Spotify.

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Rebuilding Confidence in Vaccines: Countering Misinformation During Pharmacy Visits

support@deceraclinical.com (Mary Barna Bridgeman PharmD BCPS BCGP) — Fri, 12 Dec 2025 22:06:15 +0000

Every day, I hear patients share worries shaped by the growing wave of vaccine misinformation—questions that reveal just how overwhelming today’s “infodemic” has become. In this podcast, I explore what vaccine hesitancy really looks like and how pharmacists can use empathy, strong recommendations, and meaningful dialogue to help rebuild confidence in immunization.

Presenter:
Mary Barna Bridgeman, PharmD, BCPS, BCGP
Clinical Professor
Ernest Mario School of Pharmacy
Rutgers, The State University of New Jersey
Piscataway, New Jersey
Internal Medicine Clinical Pharmacy Specialist
Robert Wood Johnson University Hospital-New Brunswick
New Brunswick, New Jersey

Link to full program:
https://bit.ly/4oHDWZq

Get access to all of our new episodes by subscribing to the Decera Clinical Education Infectious Diseases Podcast on Apple Podcasts, YouTube Music, or Spotify

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Elevating the Voices of Transgender People Living With HIV

Thu, 4 Dec 2025 20:23:13 +0000

This episode focuses on hearing the voices of transgender people living with HIV and their advocates as they share what matters most to them when it comes to healthcare services and where HIV fits among those priorities. We also consider how these insights can assist healthcare professionals in configuring HIV care to better meet the needs of this key population. Topics addressed include:

Overarching health and well-being priorities within the broader context of everyday life challenges
Personal experiences of suboptimal interactions with healthcare services, and their impact on health-seeking behaviors
Key components of a transgender-welcoming healthcare environment
Principles of people-centered care including integrating HIV care with gender-affirming care
Concerns regarding HIV management that HIV healthcare professionals should anticipate and address

Faculty:

Torrey Burke
Patient Advocate
United States

Erika Castellanos
Executive Director
Global Action for Trans Equality
The Netherlands

Aryah Lester, IC/SME
Patient Advocate
United States

Tanya Laguing
President DIOSSA (Decent Image of South Signal Association)
Hub Manager (Lily By LoveYourself x DIOSSA)
Hub Manager (Orange By LoveYourself x DIOSSA)
Taguig City, Philippines
Paranaque City, Philippines
Las Pinas, Philippines

Link to full program:
https://bit.ly/4oLXa08

Get access to all of our new podcasts by subscribing to the Decera Clinical Education Infectious Disease Podcast on Apple Podcasts, YouTube Music, or Spotify.

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Closing Gaps in STI Care Through Molecular Point-of-Care Testing

support@deceraclinical.com (Jeffrey D. Klausner MD MPH) — Tue, 2 Dec 2025 19:36:15 +0000

Molecular point-of-care testing has the potential to substantially mitigate the impact of sexually transmitted infections (STIs) on personal and public health. Listen in to learn how it may even limit the development of antimicrobial resistance. Topics covered include:

CDC and US Preventive Services Task Force STI screening recommendations
Whether or not laboratory-based STI tests contribute to increasing antibiotic resistance
Role of point-of-care testing and strategies for implementation

Presenter:
Jeffrey D. Klausner, MD, MPH
Clinical Professor of Medicine
Population and Public Health Sciences Lead
Infectious Diseases Epidemiology and Applies Studies (I.D.E.A.S.) Initiative
Keck School of Medicine of the University of Southern California
Los Angeles, California

Link to full program:
https://bit.ly/4nS7rYE

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, YouTube Music, or Spotify. 

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Testing Is Treatment: The Power of Routine HIV Screening

support@deceraclinical.com (Nancy S. Miller MD, Aniruddha (Anu) Hazra MD) — Tue, 2 Dec 2025 19:32:46 +0000

The crux of HIV care and prevention is quick and accurate diagnosis. Listen in to learn from Aniruddha (Anu) Hazra, MD, and Dr. Nancy S. Miller about the advantages and potential pitfalls of different HIV testing algorithms to find out which one is best suited for your practice.

Presenters:

Aniruddha (Anu) Hazra, MD
Associate Professor, Section of Infectious Diseases and Global Health
Medical Director, UCM Sexual Wellness Clinic
Director of STI Services, Chicago Center of HIV Elimination
Department of Medicine
University of Chicago
Chicago, Illinois

Nancy S. Miller, MD
Medical Director, Clinical Microbiology and Molecular Diagnostics
Clinical Professor, Department of Pathology and Laboratory Medicine
Boston Medical Center and Boston University Chobanian & Avedisian School of Medicine
Boston, Massachusetts

Link to full program:
https://bit.ly/4nS7rYE

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, YouTube Music, or Spotify.

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Optimizing Antibiotics in Acute Bacterial Skin and Skin Structure Infections for Today

Wed, 26 Nov 2025 19:01:57 +0000

Listen in as experts Thomas P. Lodise, PharmD, PhD, and George Sakoulas, MD, FIDSA, explore tailored antibiotic strategies for diverse patients with acute bacterial skin and skin structure infections (ABSSSIs). Their insightful discussion focuses on antibiotic developments that followed publication of the IDSA practice guidelines in 2014 and the challenges unique to ABSSSIs, including a lack of determined bacterial etiology for many cases.

Presenters

Thomas P. Lodise, PharmD, PhD
Professor
Albany College of Pharmacy and Health Sciences
Infectious Diseases Clinical Pharmacy Specialist
Stratton VA Medical Center
Albany, New York

George Sakoulas, MD, FIDSA
Chief, Infectious Diseases
Sharp Rees-Stealy Medical Group
Adjunct Professor of Pediatrics
University of California San Diego School of Medicine
San Diego, California

Link to full program:
https://bit.ly/4oIKwzs

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify. 

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Overcoming Misconceptions About Candidacy for Switch: Barriers to Optimizing ART in People Living With HIV and Viral Suppression

support@deceraclinical.com (Brian R. Wood MD, Cristina Mussini MD) — Tue, 25 Nov 2025 21:25:01 +0000

Look beyond viral suppression to learn how people living with virologically suppressed HIV may still be candidates for antiretroviral therapy (ART) switch to improve treatment satisfaction and quality of life. Topics covered include:

Reasons to consider regimen optimization in setting of viral suppression
Available switch regimens, including 2-drug regimens and long-acting ART
Approaches to assess for resistance before starting long-acting cabotegravir plus rilpivirine
DHHS recommendations on proviral DNA genotyping
ART optimization strategies for patients living with viral suppression and history of underlying resistance

Presenters:

Brian R. Wood, MD
Professor of Medicine
Division of Allergy and Infectious Diseases
University of Washington
Seattle, Washington

Cristina Mussini, MD
Professor of Infectious Diseases
Chief of the Division of Infectious Diseases, Policlinico, Modena
University of Modena and Reggio Emilia
Modena, Italy

Link to full program and accompanying slides:
https://bit.ly/4pAI66g

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Modern S. maltophilia Management: Current Concepts for Best Outcomes

support@deceraclinical.com (Ryan K. Shields PharmD MS) — Tue, 25 Nov 2025 20:46:50 +0000

Join Ryan K. Shields, PharmD, MS, in the third of 3 podcasts from our live event, “The Plot (and Sputum) Thickens: Encountering Carbapenem Resistance in Critically Ill Patients” to learn how to optimize antimicrobial regimens and develop evidence-based antibiotic management plans for complex infections caused by carbapenem-resistant bacteria. Topics covered in this segment include:

Mechanisms of resistance in S. maltophilia
Current frontline therapies
2024 IDSA guidance for treatment

Presenter:

Ryan K. Shields, PharmD, MS
Associate Professor of Medicine
Co-Director, Center for Innovative Antimicrobial Therapy
University of Pittsburgh
Co-Director, Antibiotic Management Program
UPMC Presbyterian Hospital
Pittsburgh, Pennsylvania

Link to full program and downloadable slides:
https://bit.ly/3JWaqRv

Get access to all of our new podcasts by subscribing to the Decera Clinical Education Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify. 

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Carbapenem Resistance Revisited: Reassessing Our Antibiotics of Choice

support@deceraclinical.com (Marin H. Kollef MD) — Tue, 25 Nov 2025 16:07:51 +0000

Join Marin H. Kollef, MD in the first of 3 podcasts from our live event, “The Plot (and Sputum) Thickens: Encountering Carbapenem Resistance in Critically Ill Patients” to learn how to optimize antimicrobial regimens and develop evidence-based antibiotic management plans for complex infections caused by carbapenem-resistant bacteria. Topics covered in this segment include

Antimicrobial resistance mechanisms
Diagnostic strategies for identifying resistance
Antibiotic selection strategies
Preferred and alternative antibiotics according to guideline recommendations

Presenter:

Marin H. Kollef, MD
Virginia E. and Sam J. Golman Chair in Respiratory Intensive Care Medicine
Professor of Medicine
Division of Pulmonary & Critical Care Medicine
Director, Critical Care Research
Director, Respiratory Care Services
Washington University School of Medicine
St Louis, Missouri

Link to full program and downloadable slides:

CCO:
https://bit.ly/4omLRLB

ProCE:
https://bit.ly/4pA1Xm4

Get access to all of our new podcasts by subscribing to the Decera Clinical Education Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify. 

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DTR-P. aeruginosa: Pathways to Overcoming Diverse Resistance Profiles

support@deceraclinical.com (Ryan K. Shields PharmD MS) — Tue, 25 Nov 2025 13:33:37 +0000

Join Ryan K. Shields, PharmD, MS, in the second of three recap podcasts taken from our live event, “The Plot (and Sputum) Thickens: Encountering Carbapenem Resistance in Critically Ill Patients.” Learn how to optimize antimicrobial regimens and develop evidence-based antibiotic management plans for complex infections caused by carbapenem-resistant bacteria. Topics covered in this segment include:

The diverse mechanisms of β-lactam resistance
The effect of resistance mechanisms on susceptibility to antimicrobials
2024 IDSA guidance for treatment
Considerations for antibiotic selection
The role of combination therapy

Presenter:

Link to full program and downloadable slides:

CCO:
https://bit.ly/3LXzate

ProCE:
https://bit.ly/3Mjao6G

Get access to all of our new podcasts by subscribing to the Decera Clinical Education Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify. 

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Overcoming Fear of Virologic Failure: Barriers to Optimizing ART in People Living With HIV and Viral Suppression

Fri, 21 Nov 2025 22:00:00 +0000

Fear of virologic failure is a major barrier to ensuring that people living with virally suppressed HIV are receiving the most optimal antiretroviral therapy (ART) regimen for them. Stream this Medical Minute to learn more about key guideline recommendations regarding ART switch and reassuring clinical data regarding efficacy, tolerability, and quality of life associated with switching a suppressive ART regimen. Topics covered include:

Efficacy of switching to 2-drug oral ART: real-world evidence
Real-world analyses of virologic failure with switch to long-acting cabotegravir plus rilpivirine
Patient selection to reduce risk of virologic failure with switch
Regimen-specific switch considerations

Presenters:

Dima Dandachi, MD, MPH, FIDSA, FACP
Associate Professor of Medicine
Division of Infectious Diseases
University of Missouri
Medical Director
HIV Treatment and Prevention Program, MUHC
Medical Director
Boone County Public Health and Human Services
Columbia, Missouri

Link to full program and accompanying slides:
https://bit.ly/3KPN0xb

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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The Role of Antimicrobial Stewardship Programs in Implementing Rapid Phenotypic AST

support@deceraclinical.com (Michael P. Veve PharmD MPH) — Tue, 18 Nov 2025 22:00:00 +0000

Rapid phenotypic antimicrobial susceptibility testing (AST) significantly reduces time to actionable results and can improve antibiotic decision-making for patients with bloodstream infections. Listen in to learn from Michael P. Veve, PharmD, MPH, how to optimally integrate rapid phenotypic AST into clinical practice, including incorporation into your existing antimicrobial stewardship workflow. Topics covered include:

Considerations for implementation
Decision-making steps for implementation
The role of antimicrobial stewardship programs in AST workflow

Presenter:

Michael P. Veve, PharmD, MPH
Clinical Associate Professor
Department of Pharmacy Practice
Eugene Applebaum College of Pharmacy and Health Sciences
Wayne State University
Clinical Pharmacy Specialist, Infectious Disease
Henry Ford Hospital
Detroit, Michigan

Link to full program and downloadable slides:
https://bit.ly/4inoXCx

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Integration of Genotypic RDT With Rapid Phenotypic AST for Bloodstream Infections

support@deceraclinical.com (Jose Alexander MD D(ABMM) CIC FCCM SM/MB(ASCP)) — Tue, 18 Nov 2025 22:00:00 +0000

Unnecessary broad-spectrum antibiotics can drive antimicrobial resistance and cause adverse events, whereas inadequate antibiotic coverage is linked to increased mortality and length of stay for patients with bloodstream infections (BSIs). Listen now to learn from Jose Alexander, MD, D(ABMM), CIC, FCCM, SM/MB(ASCP), how to use rapid genotypic and phenotypic antimicrobial susceptibility testing results to inform antibiotic selection for patients with gram-negative BSIs. Topics covered include:

Typical patterns of intrinsic antibiotic susceptibility and resistance in Enterobacterales
Mechanisms of resistance in gram-negative bacteria
Genotypic rapid diagnostic tests for BSIs
Resistance markers for earlier targeted therapy
Rapid phenotypic antimicrobial susceptibility test platforms for blood cultures

Presenter:

Jose Alexander, MD, D(ABMM), CIC, FCCM, SM/MB(ASCP)
Medical and Public Health Microbiologist
Medical and Technical Director of Microbiology
AdventHealth
Orlando, Florida

Link to full program and downloadable slides:
https://bit.ly/4inoXCx

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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The Ongoing Challenge of Antimicrobial Selection for Bloodstream Infections

support@deceraclinical.com (Jasmine R. Marcelin MD FACP FIDSA) — Tue, 18 Nov 2025 04:10:00 +0000

Sepsis and bloodstream infections (BSIs) are common and cause millions of deaths each year, with a disproportionate burden in low-income and middle-income countries. Tune in to learn from Jasmine R. Marcelin, MD, FACP, FIDSA, how inadequate antibiotic coverage can be linked to increased mortality and length of stay and how unnecessary broad-spectrum antibiotics can drive antimicrobial resistance. Topics covered include:

The worldwide burden of sepsis and BSIs
The ongoing threat of antimicrobial resistance
US and global health disparities in sepsis, BSI, and antimicrobial resistance
Barriers toward optimizing antibiotic use in BSIs

Presenter:

Jasmine R. Marcelin, MD, FACP, FIDSA
Associate Professor, Infectious Disease
Associate Medical Director, Antimicrobial Stewardship Program
Vice Chair for Belonging and Community Engagement, Department of Internal Medicine
Co-Director, Digital Innovation & Social Media Strategy, Division of Infectious Diseases
University of Nebraska Medical Center
Omaha, Nebraska

Link to full program and downloadable slides:
https://bit.ly/4inoXCx

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify. 

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Role of Pharmacists in PrEP Delivery

Tue, 11 Nov 2025 16:46:32 +0000

Stream this podcast to learn from experts Tessa Rife-Pennington, PharmD, BCGP, and Frank North, PharmD, MPA, DPLA, DASPL, how specialty pharmacists can apply practical strategies within different pharmacy settings to overcome barriers to PrEP use, especially among underserved patient subpopulations. Topics covered include:

PrEP candidacy
Selection of individualized regimens
Key barriers to PrEP use
Strategies for overcoming key barriers to PrEP access
Evolving state-based legislation on PrEP provision by pharmacists
Models of pharmacy-managed PrEP
Strategies for addressing inequities in PrEP care
Comprehensive HIV prevention services

Presenters:

Tessa Rife-Pennington, PharmD, BCGP
Dr. Dawn K. Smith HIV Prevention Clinical Fellow
American Academy of HIV Medicine
Volunteer Assistant Clinical Professor
University of California, San Francisco, School of Pharmacy
San Francisco, California

Frank North, PharmD, MPA, DPLA, DASPL
Instructional Assistant Professor, Irma Lerma Rangel College of Pharmacy
Director of Learning in Practice
Office of Interprofessional Practice, Education and Research
Texas A&M University Health Science Center
Past President, National Pharmaceutical Association
College Station, Texas

Link to full program:
https://bit.ly/49SLc0y

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Forging a Path Back to HIV Care

support@deceraclinical.com (Lauren Harris Jackson, Shellye Jones MSW LCSW) — Tue, 21 Oct 2025 12:43:55 +0000

In this episode, expert patient navigators Shellye Jones and Lauren Jackson discuss the key take-home points of our online educational program on facilitating engagement in HIV care and propose a framework for effectively retaining people in care. Topics covered include:

How to approach a patient with complex barriers to engagement in healthcare
Resources for staying in care, such as wraparound services
Setting SMART goals and formulating action plans with patients
Deconstructing stigma and implementing a trauma-informed approach to care

Presenters:

Shellye Jones, MSW, LCSW
Clinical Supervisor
Charles R. Drew University, Drew CARES
Los Angeles, California

Lauren Harris Jackson
Street Medicine Patient Navigator
Healthcare in Action
Los Angeles, California

Link to full program:
https://bit.ly/3Wh4Z1T

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Overcoming Reluctance to Change as a Barrier to Optimizing ART for People Living With HIV and Viral Suppression

support@deceraclinical.com (Luis Buzon Martin MD, Monica Gandhi MD MPH) — Thu, 16 Oct 2025 17:14:15 +0000

Don’t settle! Listen in to learn how a proactive approach to ART switch can improve treatment satisfaction and quality of life for people living with virologically suppressed HIV. Topics covered include:

International AIDS Society (IAS) USA and European AIDS Clinical Society (EACS) Guidance on Switching ART With Viral Suppression
Considerations for switching to a 2-drug regimen or long-acting ART
Methods for assessing patient satisfaction with their current ART regimen

Presenters:

Monica Gandhi, MD, MPH
Director, UCSF-Bay Area Center for AIDS Research (CFAR)
Professor of Medicine and Associate Chief, Division of HIV, Infectious Diseases, and Global Medicine
Medical Director, “Ward 86” HIV Clinic, San Francisco General Hospital
University of California, San Francisco (UCSF)
San Francisco, California

Luis Buzon Martin, MD
Division of Infectious Diseases
Hospital Universitario de Burgos
Burgos, Espana

Link to full program and accompanying slides:
https://bit.ly/3KPN0xb

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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HIV “Blips”: What They Are (and Aren’t)

support@deceraclinical.com (Brian R. Wood MD) — Wed, 8 Oct 2025 14:30:25 +0000

Detectable HIV-1 RNA (viral load) can seem very worrisome for people living with HIV who are receiving antiretroviral therapy (ART) and for their healthcare professionals. Tune in to learn how Brian R. Wood, MD, differentiates HIV-1 RNA “blips” from persistent low-level viremia and from virologic failure, and how he handles each scenario.

Presenter:

Brian R. Wood, MD
Professor of Medicine
Division of Allergy and Infectious Diseases
University of Washington
Seattle, Washington

Link to full program:
https://bit.ly/4nS7rYE

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Individualizing Care for Treatment-Experienced People With HIV

support@deceraclinical.com (Clíona Ní Cheallaigh MB MRCP PhD) — Fri, 26 Sep 2025 20:34:13 +0000

Tune into this podcast from Dr Clíona Ní Cheallaigh to learn how to provide person-centered care for treatment-experienced people with HIV. Gain strategies to address each individual’s specific history and needs while considering the potential impact of comorbidities and other health challenges. Topics covered include:

Individualizing Antiretroviral Regimens for Treatment-Experienced People With HIV
Strategies to Improve Adherence and Addressing Barriers to Engagement in Care
Person-Centered, Trauma-Informed Care
Resistance Testing in the Setting of Virologic Failure
Selection of ARVs With a Failing Regimen

Presenters:
Clíona Ní Cheallaigh, MB, MRCP, PhD
Consultant Physician
Inclusion Health Services
St James’s Hospital Dublin
Associate Professor
Department of Medicine
Trinity College Dublin
Dublin, Ireland

Link to full program:
https://bit.ly/4oiYxEx

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Clinical Scenarios Podcast: A Deep Dive Into Refractory CMV Infections

Wed, 3 Sep 2025 21:10:00 +0000

In this podcast, expert faculty Atul Humar, MD, FRCP (C), and Camille Kotton, MD, FIDSA, FAST, take a deep dive into complex clinical scenarios and explore designing antiviral regimens for refractory CMV infections to minimize antiviral toxicities and maximize efficacy. Topics covered include:

Management for suspected drug-resistant CMV infection
Illustrative patient cases
Gene mutations in CMV

Presenters:

Atul Humar, MD, FRCPC, FAST
Professor
Department of Medicine
University of Toronto
Eaton Family Chair in Transplant Infectious Diseases
Ajmera Transplant Centre
University Health Network
Toronto, Canada

Camille Kotton, MD, FIDSA, FAST
Clinical Director, Transplant and Immunocompromised Host Infectious Diseases
Infectious Diseases Division
Mass General Brigham Endowed Cancer Chair IV
Massachusetts General Hospital
Associate Professor, Harvard Medical School
Boston, Massachusetts

Link to full program:
https://bit.ly/4lOa2kA

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Soundings Podcast: Identifying Refractory CMV Infections in Transplant Settings

support@deceraclinical.com (Camille Kotton MD FIDSA FAST) — Fri, 29 Aug 2025 21:05:00 +0000

Tune in to learn the fundamentals for timely identification of refractory cytomegalovirus (CMV) infections following solid organ transplantation from expert faculty, Camille Kotton, MD, FIDSA, FAST. Topics covered include:

Direct and indirect effects of CMV infection
Risk factors for resistant/refractory CMV
Defining resistant/refractory CMV

Presenter:
Camille Kotton, MD, FIDSA, FAST
Clinical Director, Transplant and Immunocompromised Host Infectious Diseases
Infectious Diseases Division
Mass General Brigham Endowed Cancer Chair IV
Massachusetts General Hospital
Associate Professor, Harvard Medical School
Boston, Massachusetts

Link to full program:
http://bit.ly/4lOa2kA

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Charting the Course Podcast: Antivirals for Refractory CMV Infections

support@deceraclinical.com (Atul Humar MD FRCP (C)) — Fri, 29 Aug 2025 21:05:00 +0000

Learn to appropriately modify antiviral therapy in solid organ transplant recipients with treatment-refractory cytomegalovirus (CMV) infections with expert faculty, Atul Humar, MD, FRCP (C). Topics covered include:

Comparisons of available CMV antiviral therapies:
- Ganciclovir, valganciclovir, foscarnet, cidofovir, maribavir
Considerations for renal function monitoring with ganciclovir and valganciclovir
A treatment algorithm for relapsed/refractory CMV
The latest clinical trial data and guideline recommendations

Presenter:
Atul Humar, MD, FRCP (C)
Professor
Department of Medicine
University of Toronto
Eaton Family Chair in Transplant Infectious Diseases
Ajmera Transplant Centre
University Health Network
Toronto, Canada

Link to full program:
https://bit.ly/4lOa2kA

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify

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The Patient Angle: Individualized Approaches for Managing CMV

Tue, 26 Aug 2025 21:00:00 +0000

Listen in as Dr Marcus Pereira and Dr Raymund R. Razonable explore strategies for individualization of CMV management in high-risk kidney transplant recipients. Topics include:

Risk factors and prevention of late-onset CMV disease
Early detection of late CMV infection
CMV cell-mediated immunity monitoring
Primary and secondary prophylaxis

Presenters:

Raymund R. Razonable, MD, FIDSA, FAST
Professor of Medicine
Division of Infectious Diseases
Mayo Clinic College of Medicine and Science
Rochester, Minnesota

Link to full program:
https://bit.ly/41ejruC

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify. 

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The Viral Angle: CMV in Kidney Transplantation

Tue, 26 Aug 2025 20:55:00 +0000

Listen in as Dr Marcus Pereira and Dr Raymund R. Razonable discuss the fundamentals of cytomegalovirus (CMV) in kidney transplant recipients. Topics include:

CMV pathogenesis
Direct and indirect effects of CMV infection
Overview of patient risk factors
CMV risk based on serologic status

Presenters:

Raymund R. Razonable, MD, FIDSA, FAST
Professor of Medicine
Division of Infectious Diseases
Mayo Clinic College of Medicine and Science
Rochester, Minnesota

Link to full program:
https://bit.ly/41ejruC

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify. 

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Syndromic Testing Podcast: Gastrointestinal and Joint Infections

support@deceraclinical.com (Trevor Van Schooneveld MD) — Tue, 26 Aug 2025 17:40:40 +0000

Listen in as Dr Trevor Van Schooneveld explores rapid syndromic testing for gastrointestinal and joint infections and discusses how to apply best practices for diagnostic and antimicrobial stewardship in syndromic testing.

Topics covered include:

Who should be tested for infectious diarrhea
Types of gastrointestinal syndromic panels
Types of syndromic panels for joint infections
Real-world applications for joint syndromic panels

Presenters:

Trevor Van Schooneveld, MD
Professor, Division of Infectious Diseases
Medical Director, Antimicrobial Stewardship Program
Department of Internal Medicine
University of Nebraska Medical Center
Omaha, Nebraska

Link to full program:
https://bit.ly/4mHOTtW

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify. 

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The Antiviral Angle: Leveraging the Full CMV Armamentarium

support@deceraclinical.com (Marcus Pereira MD MPH FAST) — Tue, 26 Aug 2025 15:46:41 +0000

Listen in as Dr Marcus Pereira discusses how to design cytomegalovirus (CMV) antiviral regimens for high-risk kidney transplant recipients to mitigate the impact of infection while minimizing drug toxicities. Topics include:

Strategies for CMV prevention: prophylaxis, preemptive therapy, and hybrid methods
Characteristics of available antiviral drugs
Monitoring considerations for antivirals

Presenters:

Link to full program:
http://bit.ly/41ejruC

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify. 

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Heartbreak to Hope: My Journey With Meningitis Vaccine Advocacy

support@deceraclinical.com (Alicia Stillman MBA MPH) — Mon, 25 Aug 2025 20:55:00 +0000

Join Alicia Stillman of the American Society for Meningitis Prevention, as she shares a very personal story of loss that might change how you view meningitis vaccination.

Presenter:

Alicia Stillman, MBA, MPH
Patient Advocate
Co-Executive Director, American Society for Meningitis Prevention
Executive Director, Emily Stillman Foundation
Detroit, Michigan

Link to full program:
https://bit.ly/4mYvTXQ

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify. 

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Syndromic Testing Podcast: Respiratory Infections

support@deceraclinical.com (Michael Satlin MD MS FIDSA) — Tue, 19 Aug 2025 14:04:16 +0000

Listen in as Michael Satlin, MD, MS, FIDSA,explores rapid syndromic testing for bloodstream infections and discusses how to apply best practices for diagnostic and antimicrobial stewardship in syndromic testing.

Topics covered include:

Types of upper and lower respiratory infection panels
Considerations for when to use respiratory syndromic testing
How to use syndromic testing to guide both therapy escalation and de-escalation
How syndromic testing fits in with traditional testing methods, such as culture, antimicrobial susceptibility testing, Gram stain, and BAL cell count

Presenter:

Michael Satlin, MD, MS, FIDSA
Associate Professor of Medicine and Pathology and Laboratory Medicine
Weill Cornell Medicine
New York, New York

Link to full program:
https://bit.ly/3UAB1oU

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Advancing HIV Treatment: Leveraging Pharmacists’ Expertise

Mon, 18 Aug 2025 15:50:21 +0000

Stream this podcast to learn from experts Alexis E. Horace, PharmD, BCACP,andNimish Patel, PharmD, PhD, AAHIVP, how specialist pharmacists can overcome key barriers to care and apply best practices for optimization of antiretroviral therapy for HIV. Topics covered include:

Leveraging pharmacists’ expertise to advance HIV treatment
Pharmacist roles in HIV care and management
The current ART landscape
Regimen simplification
Consideration of patient preferences, health factors, and comorbidities for ART optimization
ART management for treatment-experienced patients, including those with multidrug-resistant HIV

Presenters:

Alexis E. Horace, PharmD, BCACP
Professor of Pharmacy Practice
University of Louisiana at Monroe College of Pharmacy
New Orleans Campus
CrescentCare Ambulatory Care Clinical Pharmacist, HIV Specialty
New Orleans, Louisiana

Nimish Patel, PharmD, PhD, AAHIVP
Professor of Clinical Pharmacy
Division of Clinical Pharmacy
Skaggs School of Pharmacy & Pharmaceutical Sciences
University of California, San Diego
La Jolla, California

Link to full program:
https://bit.ly/41agtqQ

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Lenacapavir Approval: What to Know When Selecting a PrEP Regimen

Wed, 13 Aug 2025 15:06:59 +0000

Tune in to learn how the recent FDA approval of lenacapavir (LEN) for PreP integrates into the current field of HIV prevention. Listen on the go or follow along with our expert-curated slides. Topics covered include:

The current landscape of PrEP
FDA approval of lenacapavir
Phase III efficacy and safety data for lenacapavir
Recommendations and perspectives on the future of PrEP

Presenters:

Colleen F. Kelley, MD, MPH
Professor of Medicine
Division of Infectious Diseases
Department of Medicine
Co-Director, Emory Center for
AIDS Research
Associated Dean for Research,
Emory at Grady
Emory University School of Medicine
Atlanta, Georgia

Raphael J. Landovitz, MD, MSc
Professor of Medicine
Chief, Division of Infectious Diseases
Associate Vice Chair for
Clinical Research
Department of Medicine
David Geffen School of Medicine
University of California, Los Angeles
Director, UCLA Center for Clinical AIDS Research & Education (CARE)
Director, Center for HIV Identification, Prevention, and Treatment Services (CHIPTS)
Los Angeles, California

Link to full program:
https://bit.ly/4m8RaOg

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Key HIV Studies Influencing My Practice Following IAS 2025—Dr Beatriz Grinsztejn and Rosie Mngqibisa

Tue, 12 Aug 2025 15:20:57 +0000

Hear from experts in HIV care Beatriz Grinsztejn, MD, PhD, and Rosie Mnggibisa, MBChB, MPH, as they discuss their insights on some of the most clinically relevant new data presented at IAS 2025, including studies on:

Gaps in care for adolescents and young adults living with HIV
Global impact of funding cuts
Antiretroviral therapy for treating HIV
Patient management strategies for people living with HIV and obesity

Presenters:

Beatriz Grinsztejn, MD, PhD
Director
STI/HIV Clinical Research Laboratory
Evandro Chagas National Institute of Infectious Diseases – FIOCRUZ
Rio de Janeiro, Brazil

Rosie Mngqibisa, MBChB, MPH
Clinical Director
Principal Investigator
Enhancing Care Foundation
Durban, South Africa

Link to full program:
https://bit.ly/4otF8AR

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Syndromic Testing Podcast: Bloodstream Infections

support@deceraclinical.com (Emily Heil PharmD MS BCIDP AAHIVP) — Tue, 12 Aug 2025 12:50:17 +0000

Listen in as Dr Emily Heil explores rapid syndromic testing for bloodstream infections and discusses how to apply best practices for diagnostic and antimicrobial stewardship in syndromic testing.

Topics covered include:

The importance of good blood culture practices and finding the balance between overuse and underuse
Blood culture improvement programs
The utility of rapid diagnostic tests
Resistance markers for earlier targeted therapy

Presenters:

Emily Heil, PharmD, MS, BCIDP, AAHIVP
Professor
Department of Practice, Sciences, and Health Outcomes Research
University of Maryland School of Pharmacy
Baltimore, Maryland

Link to full program:
https://bit.ly/45Ajz92

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Fundamentals on Integrating Specialized Agents for Treatment-Experienced People With HIV

support@deceraclinical.com (Georg Behrens MD) — Mon, 11 Aug 2025 21:05:00 +0000

Tune in as Dr George Behrenspresents the fundamentals on specialized agents for treatment-experienced people living with HIV.

Topics covered include:

Key targets and mechanisms of action for specialized HIV drugs
Clinical trial data supporting safety and efficacy of these agents
Considerations for potential drug–drug interactions
Strategies for leveraging these agents to construct new ART regimens for treatment-experienced individuals

Presenters:

Georg Behrens, MD
Professor of Immunology
Senior Consultant
Department of Rheumatology and Immunology
Hannover Medical School, Germany
Hannover, Germany

Link to full program:
https://bit.ly/4oiYxEx

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Essentials for ART Selection for Treatment-Experienced People With HIV and Comorbidities

support@deceraclinical.com (Josep M. Llibre MD PhD) — Fri, 8 Aug 2025 21:00:00 +0000

In this episode, Dr Josep M. Llibrereviews the essentials on ART selection for treatment-experienced people with HIV and comorbidities.

Topics covered include:

Underlying reasons for development of multidrug-resistant HIV
Inflammation and immune activation associated with frequency of age-related conditions
General principles for designing ART regimens for persons with multidrug-resistant HIV
Treatment options for highly treatment‒experienced people
Considerations for comorbidities and drug–drug interactions

Presenters:

Josep M. Llibre, MD, PhD
Senior Consultant
Infectious Diseases Division
Fight Infections Foundation
University Hospital Germans Trias
Badalona, Barcelona, Spain

Link to full program:
https://bit.ly/4oiYxEx

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Key Principles for Getting Started With Managing Multidrug-Resistant HIV

support@deceraclinical.com (Decera Clinical Education) — Tue, 5 Aug 2025 17:00:22 +0000

Tune in as Dr Daniel R. Kuritzkes presents a quick and easy primer on managing multidrug resistant HIV.

Topics covered include:

How to recognize key populations who may present with multidrug-resistant HIV
Identifying underlying reasons for regimen failure
Evaluating resistance profiles
Constructing new ART regimens for treatment-experienced individuals.

Presenters:

Daniel R. Kuritzkes, MD
Chief, Division of Infectious Diseases
Brigham and Women's Hospital
Harriet Ryan Albee Professor of Medicine
Harvard Medical School
Boston, Massachusetts

Link to full program:
https://bit.ly/4oiYxEx

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Key PBC Studies From EASL and DDW 2025

support@deceraclinical.com (Palak Trivedi BSc MBBS PhD MRCP ESEGH) — Mon, 7 Jul 2025 17:50:30 +0000

In this episode, Palak J. Trivedi, BSc, MBBS, PhD, MRCP, ESEGH, discusses the most recent developments in primary biliary cholangitis (PBC) treatment, including cutting-edge data on new and emerging agents and how these updates may be integrated into your practice. Topics include:

Steatotic liver disease and PBC
Vibration-controlled transient elastography (VCTE) and discordant biochemical responses in PBC
PPAR agonists and IBATs for PBC treatment

Presenter:

Palak J. Trivedi, BSc, MBBS, PhD, MRCP, ESEGH
Associate Professor
NIHR Birmingham BRC
University of Birmingham
Consultant Hepatologist, Liver Unit
University Hospitals Birmingham
Birmingham, United Kingdom

Link to full program:
https://bit.ly/4lKaO2H

Follow along with the slides:
https://bit.ly/44PPBys

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Expert Insights for Transforming Your Practice Into a Vaccine Center of Excellence

Mon, 30 Jun 2025 17:31:26 +0000

Listen as expert faculty answer your most pressing questions on optimizing immunization in clinical practice.

Topics covered include:

Practical methods for improving confidence in vaccines
How to educate patients on vaccine development and safety monitoring
Effective strategies to tailor recommendations, such as motivational interviewing
Ways to navigate clinical encounters and address vaccine hesitancy

Presenters:
Robert H. Hopkins, Jr., MD, MACP
Professor of Internal Medicine and Pediatrics
University of Arkansas for Medical Sciences
College of Medicine
Little Rock, Arkansas

Litjen (L.J.) Tan, MS, PhD
Chief Policy and Partnership Office, Immunize.org
Chair, National Adult Influenza Immunization Summit
Co-Chair, Global Influenza Initiative
St Paul, Minnesota

Link to full program:
https://bit.ly/3I5jBh0

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Partnering With Patients for PBC Care: Actionable Strategies for HCPs

Thu, 26 Jun 2025 19:03:35 +0000

In this episode, Dr Gideon Hirschfield meets with patient advocate Jess Schnur to discuss challenges related to the diagnosis and management of primary biliary cholangitis (PBC) to provide actionable strategies for healthcare professionals to incorporate into patient care, including:

Disease concerns and frequently asked questions from a patient perspective
Managing symptoms
Treatment options and supportive care
Importance of awareness and education

Presenters:
Gideon Hirschfield, MA, MB BChir, FRCP, PhD
Lily and Terry Horner Chair in Autoimmune Liver Disease Research
Professor, Division of Gastroenterology and Hepatology
University of Toronto
Director, The Autoimmune and Rare Liver Disease Programme
Director, Francis Family Liver Clinic
Toronto General Hospital, University Health Network
Ontario, Canada

Jess N. Schnur, BSN-RN
National PBC Patient Advocate
American Liver Foundation
Donation Support Services Coordinator
Lifeline of Ohio
Columbus, Ohio

To learn more, see the program
Hear Me: Patient Perspectives on PBC

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PBC Perspectives: A Patient and HCP in Conversation

support@deceraclinical.com (Sonal Kumar MD MPH, Maria Morais RN) — Thu, 26 Jun 2025 18:50:15 +0000

In this podcast, Sonal Kumar, MD, MPH, meets with patient advocate Maria Morais to discuss actionable steps that healthcare providers can incorporate into the care of people with primary biliary cholangitis (PBC). Listen as they discuss:

The chronic nature of PBC
Going beyond biochemical markers to assess and address symptoms such as fatigue and pruritus
The importance of referral to patient support groups

Presenters:

Sonal Kumar, MD, MPH
Assistant Professor of Medicine
Director, General Gastroenterology and Hepatology
Weill Cornell Medical College
New York, New York

Maria G. Morais, RN
VP Patient Advocacy
Canadian PBC Society
Toronto, Canada

To learn more, see the program
Hear Me: Patient Perspectives on PBC

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Debating the Role of ALP Normalization in PBC: Curbside Consults Podcast

support@deceraclinical.com (Stuart C. Gordon MD, Nancy Reau MD) — Thu, 26 Jun 2025 18:44:28 +0000

In this podcast, expert faculty, Dr Stuart Gordon and Dr Nancy Reau, use an illustrative patient case to explore the roles of ALP and other biochemical markers in PBC management, and explain what to expect from treatment. Topics covered include:

How baseline ALP can affect ALP normalization after second-line treatment with elafibranor and seladelpar
Potential outcomes if ALP normalization cannot be achieved
The importance of managing fatigue, pruritus, and sleep disturbances independently of the biochemical response

Presenters:

Stuart C. Gordon, MD
Professor of Medicine
Wayne State University School of Medicine
Director, Division of Hepatology
Henry Ford Health
Detroit, Michigan

Nancy Reau, MD
Professor of Medicine
Richard B. Capps Chair of Hepatology
Chief, Section of Hepatology
Associate Director, Solid Organ Transplantation
Rush University Medical Center
Chicago, Illinois

To learn more about PBC management, check out our program,
Curbside Consults: Expert Insights on Challenges in PBC Management.

Supported by educational grants from Gilead Sciences, Inc. and Ipsen Biopharmaceuticals, Inc

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Managing PBC Therapy for Patients With Cirrhosis: Curbside Consults Podcast

support@deceraclinical.com (Stuart C. Gordon MD, Nancy Reau MD) — Thu, 26 Jun 2025 18:30:08 +0000

In this podcast, expert faculty, Dr Stuart Gordon and Dr Nancy Reau discuss an illustrative patient case to demonstrate how they individualize primary biliary cholangitis (PBC) therapy for patients with cirrhosis. Topics covered include:

AASLD guideline recommendations for second-line therapy for PBC
Considerations when using newer agents for second-line treatment of PBC in patients with cirrhosis: elafibranor and seladelpar

Presenters:

Stuart C. Gordon, MD
Professor of Medicine
Wayne State University School of Medicine
Director, Division of Hepatology
Henry Ford Health
Detroit, Michigan

To learn more about PBC management, check out our program,
Curbside Consults: Expert Insights on Challenges in PBC Management.

Supported by educational grants from Gilead Sciences, Inc. and Ipsen Biopharmaceuticals, Inc

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Innovations in NCFBE: Understanding the Patient Burden and Best Practices in Diagnostics

Wed, 18 Jun 2025 18:20:50 +0000

In this podcast, Brett M. Elicker, MD, and David E. Griffith, MD, ATSF, FACCP, FRSM, discuss the pathophysiology of non–cystic fibrosis bronchiectasis (NCFBE), the patient burden, and best practices with diagnosing NCFBE, including:

The vicious vortex of NCFBE (ie, airway dysfunction, inflammation, infection)
Cough as the most significant symptom and burden
Imaging bronchiectasis with classic and inflammatory findings
Differentiating the causes of NCFBE to inform patient care

Presenters

Brett M. Elicker, MD
Professor of Clinical Radiology
Chief, Cardiothoracic Imaging Division
Department of Radiology & Biomedical Imaging
University of California, San Francisco
San Francisco, California

David E. Griffith, MD, ATSF, FACCP, FRSM
Professor of Medicine
Division of Mycobacterial and Respiratory Diseases
Department of Medicine
National Jewish Health
Denver, Colorado

Program page:
https://bit.ly/4mZbYsm

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Evaluating and Managing PBC Symptoms: Curbside Consults Podcast

support@deceraclinical.com (Alan Bonder MD AGAF, Aparna Goel MD) — Wed, 18 Jun 2025 17:17:29 +0000

In this podcast, listen as experts Alan Bonder, MD, AGAF, and Aparna Goel, MD, discuss how they assess the symptoms of primary biliary cholangitis (PBC) and explore how new therapeutic agents may help alleviate symptom burden. Topics include:

Strategies and tools for assessing pruritus
Nonpharmacologic and pharmacologic management of pruritus
Second-line agents and their impact on pruritus
Investigational treatments for pruritus

Presenters:

Alan Bonder, MD, AGAF
Associate Professor of Medicine
Medical Director of Liver Transplant
Department of Gastroenterology
Beth Israel Deaconess Medical Center
Harvard Medical School
Boston, Massachusetts

Aparna Goel, MD
Associate Clinical Professor of Medicine
Division of Gastroenterology and Hepatology
Stanford University
Palo Alto, California

Content based on an online CME program supported by independent educational grants from Gilead Sciences, Inc., and Ipsen Biopharmaceuticals, Inc.

To learn more about PBC management, check out our program, Curbside Consults: Expert Insights on Challenges in PBC Management.

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Defining Nonresponse to PBC Treatment: Curbside Consults Podcast

support@deceraclinical.com (Alan Bonder MD AGAF, Aparna Goel MD) — Wed, 18 Jun 2025 17:00:26 +0000

How do you decide when to move from first-line to second-line treatment for primary biliary cholangitis (PBC)? In this podcast, listen as experts Alan Bonder, MD, AGAF, and Aparna Goel, MD, discuss this question and more, including:

How and when to measure treatment response
Evidence-based goals of therapy
Considerations for second-line treatment
New agents for second-line treatment: PPAR agonists

Presenters:

Aparna Goel, MD
Associate Clinical Professor of Medicine
Division of Gastroenterology and Hepatology
Stanford University
Palo Alto, California

Content based on an online CME program supported by independent educational grants from Gilead Sciences, Inc., and Ipsen Biopharmaceuticals, Inc.

To learn more about PBC management, check out our program,
Curbside Consults: Expert Insights on Challenges in PBC Management.

Supported by educational grants from Gilead Sciences, Inc. and Ipsen Biopharmaceuticals, Inc

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Listen Up: Time to Prioritize RSV Vaccination for Adults

support@deceraclinical.com (Ruth Carrico, Audrey M. Stevenson) — Wed, 11 Jun 2025 15:45:52 +0000

Respiratory Syncytial Virus (RSV) significantly impacts adults, especially those over age 60 and those with chronic conditions.

In this podcast, nurse practitioners Drs. Carrico and Stevenson discuss the underestimated burden of RSV. The podcast also explores practical strategies for increasing vaccine uptake that you can apply to your practice starting today so that you can protect your patients against RSV.

Listen as they discuss:

The Burden of Adult RSV
RSV Vaccines for Adults: Data and Recommendations
RSV Vaccine Uptake
Practical Strategies to Increase RSV Vaccine Uptake

Faculty:

Dr. Ruth Carrico is a family nurse practitioner and senior consultant with Carrico & Ramirez, PLLC focused on infectious diseases, infection prevention and control, and vaccinology. She is based in Louisville, Kentucky and is a Professor, adjunct faculty, with the University of Louisville School Medicine, Division of Infectious Diseases. Dr. Carrico has received training specific for healthcare epidemiology at the Centers for Disease Control and Prevention (CDC) in conjunction with the Rollins School of Public Health at Emory University in Atlanta and the Society for Healthcare Epidemiology of America (SHEA).

Dr. Carrico has worked in the field of infectious diseases and infection control for more than thirty years. Dr. Carrico also maintains a clinical practice focused on vaccines, vaccination, and immunization processes.

Dr. Audrey M. Stevenson is a family nurse practitioner with over 40 years of clinical, public health, and leadership experience.

Dr. Stevenson, who holds a master of public health and master of nursing degrees, received her doctorate in public health from the University of Utah. She formerly worked in public health for over 34 years and was the former Division Director of Family Health and Clinical Services of the Salt Lake County Health Department in Salt Lake City, Utah. She currently works as a consultant and teaches graduate FNP and MPH students at two universities.

Dr. Stevenson is also a member of the statewide vaccine advisory board, where she collaborates on vaccine policies and recommendations for the state. Previously, Dr. Stevenson served as Vaccination Branch Director for the COVID-19 Incident Command for Salt Lake County, where she directed the vaccination strategies for 1.2 million residents of Salt Lake County. She has been a vaccine champion for over 30 years.

Learn more:
Download this practical infographic to help you integrate RSV vaccination into your clinical practice.
https://bit.ly/43mzacq

For more information for nurses, subscribe to the PCE podcast channel on your favorite player!

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Paving the Way: Overcoming Barriers to RSV Vaccination

support@deceraclinical.com (Laura P. Hurley MD MPH, Carolyn Bridges MD FACP) — Mon, 2 Jun 2025 21:25:00 +0000

Listen in as Carolyn Bridges, MD, FACP, and Laura P. Hurley, MD, MPH, discuss barriers to respiratory syncytial virus (RSV) vaccination for adults, including insurance coverage and vaccine hesitancy, and explore effective, practical strategies for overcoming these barriers. Topics covered include:

Helping patients understand why they need an RSV vaccine
Ways to discuss real-world vaccine efficacy
Approaches to build vaccine confidence and discuss vaccine safety
Methods to overcome financial barriers and time constraints
Vaccine delivery infrastructure

Presenters:

Carolyn Bridges, MD, FACP
Consulting Physician and Director of Adult Immunizations
Immunize.org
St Paul, Minnesota

Laura P. Hurley, MD, MPH
Associate Professor of Medicine
Division of General Internal Medicine
University of Colorado Anschutz Medical Campus
Aurora, Colorado
General Internist and Health Services Researcher
Denver Health
Denver, Colorado

Link to full program:
https://bit.ly/4mHHKu2

Downloadable slides:
https://bit.ly/3FzWREP

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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The Latest Data and Guidelines for Adult RSV Vaccines

support@deceraclinical.com (Carolyn Bridges MD FACP) — Mon, 2 Jun 2025 21:20:00 +0000

Listen in as Carolyn Bridges, MD, FACP, reviews the estimated burden of respiratory syncytial virus (RSV) disease in older adults and discusses the latest updates on RSV vaccination recommendations and safety data. Topics covered include:

Rates of RSV hospitalizations and emergency department visits
RSV vaccine development
FDA-approved RSV vaccines
Vaccine safety data: rates of atrial fibrillation and Guillain-Barré syndrome
ACIP RSV vaccine recommendations
Risk factors for severe RSV disease
RSV vaccine uptake

Presenter:
Carolyn Bridges, MD, FACP
Consulting Physician and Director of Adult Immunizations
Immunize.org
St Paul, Minnesota

Link to full program:
https://bit.ly/4mHHKu2

Downloadable slides:
https://bit.ly/3FzWREP

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Overcoming Common Hurdles to RSV Vaccination in Post-acute and Long-term Care

support@deceraclinical.com (Jewel Mullen MD MPH MPA, Dallas Nelson MD CMD FACP) — Thu, 10 Apr 2025 13:23:03 +0000

In this episode, Jewel Mullen, MD, MPH, MPA, and Dallas Nelson, MD, CMD, FACP discuss overcoming barriers to RSV vaccine uptake in post-acute and long-term care facilities, including:

How to incorporate the latest RSV vaccination recommendations into clinical practice
Practical strategies for navigating insurance
Effective and empathetic methods of addressing vaccine hesitancy.

Presenters:

Jewel Mullen, MD, MPH, MPA
Associate Dean for Health Equity
Associate Professor of Population Health and Internal Medicine
University of Texas at Austin Dell Medical School
Austin, Texas

Dallas Nelson, MD, CMD, FACP
Professor of Medicine
Division of Geriatrics and Aging
University of Rochester
Medical Director
UR Medicine Geriatrics Group
Rochester, New York

Link to full program:
https://bit.ly/4lrwa5u

Follow along with the slides:
https://bit.ly/3RdWAKe

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Key HIV Studies Influencing My Practice Following CROI 2025—Dr Chloe Orkin and Dr Jean-Michel Molina

Fri, 4 Apr 2025 21:10:00 +0000

In this episode, Chloe Orkin, MBChB, FRCP, MD, and Jean-Michel Molina, MD, PhD, discuss highlights from CCO’s independent conference coverage of CROI 2025, including:

Advances in HIV treatment based on results from CARES
Potential HIV therapies in the pipeline, such as doravirine/islatravir
Effects of broadly neutralizing antibodies on HIV treatment and cure
Key clinical data on HIV and STI prevention obtained from PILLAR, HPTN 083, PURPOSE 1, and STOMP

Presenters:
Chloe Orkin, MBChB, FRCP, MD
Professor of Infection and Inequities
Dean for Healthcare Transformation
Honorary Consultant Physician, Barts Health NHS Trust
Faculty of Medicine and Dentistry
Queen Mary University of London
London, United Kingdom

Jean-Michel Molina, MD, PhD
Professor of Medicine
University of Paris Cite
Department of Infectious Diseases
Saint-Louis and Lariboisiere Hospitals, APHP
Paris, France

Link to full program:
bit.ly/3E1bAYQ

To access all of our new podcast episodes, subscribe to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify. 

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COVID-19 in EU: Inpatient Treatment Options for Severe COVID-19 in People Who Are Immunocompromised

Thu, 13 Mar 2025 17:28:31 +0000

Listen in as Cristina Mussini, MD; Martin Witzenrath, MD, FERS; and Michele Bartoletti, MD, PhD, discuss treatment strategies for people who are immunocompromised with COVID-19 in the hospital setting, including:

Antiviral therapy with remdesivir
Dexamethasone for patients with hematologic malignancies
Considerations regarding other immunomodulators such as JAK inhibitors or IL-6 inhibitors
A detailed patient case to illustrate key takeaways

Presenters:

Michele Bartoletti, MD, PhD
Associate Professor of Infectious Diseases
Department of Biomedical Sciences
Humanitas University
Pieve Emanuele (MI), Italy
Head of Infectious Diseases Unit
IRCCS Humanitas Research Hospital
Rozzano (MI), Italy

Cristina Mussini, MD
Full Professor of Infectious Diseases
Chief of the Department of Infectious Diseases
University of Modena and Reggio Emilia
Modena, Italy

Martin Witzenrath, MD, FERS
Medical Director
Charite Centrum 12
Internal Medicine & Dermatology
Professor and Chair for Respiratory Medicine and Critical Care
Department of Infectious Disease, Respiratory Medicine and Critical Care
Charite Campus Mitte/Campus Virchow Klinikum/Campus Benamin Franklin
Charite – University of Berlin
Berlin, Germany

Link to full program:
https://bit.ly/4fs7Hcb

Downloadable slides:
https://bit.ly/3XP1fpJ

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Treatment Options for Severe COVID-19 in Patients Who Are Immunocompromised

Mon, 10 Mar 2025 17:24:17 +0000

In this episode, Stephen Cantrill, MD, FACEP; Rajesh T. Gandhi, MD; and Payal K. Patel, MD, MPH, FIDSA, discuss treatment strategies for people who have severe COVID-19, including:

Antiviral therapy with remdesivir
Dexamethasone and other systemic corticosteroids
Immunomodulators, such as JAK inhibitors or IL-6 inhibitors
Overviews of clinical trial data demonstrating how and when to use these therapies

Presenters:

Stephen Cantrill, MD, FACEP
Associate Director and Medical Director (Retired)
Department of Emergency Medicine
Denver Health Medical Center
Associate Professor
Department of Emergency Medicine
University of Colorado Health Sciences Center
Denver, Colorado

Rajesh T. Gandhi, MD
Massachusetts General Hospital
Professor of Medicine
Harvard Medical School
Boston, Massachusetts

Payal K. Patel, MD, MPH, FIDSA
Systemwide Director of Antimicrobial Stewardship
Associate Professor, Division of Infectious Diseases
Intermountain Health
Salt Lake City, Utah

Link to full program:
https://bit.ly/4gu2gcU

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Simplifying HBV Screening and Care: Paths to Elimination

Mon, 10 Mar 2025 16:26:20 +0000

In this episode, Patricia D. Jones, MD, MSCR; Mindie H. Nguyen, MD, MAS, AGAF, FAASLD; and patient advocate, Jennifer Wild, MS, RN, OCN, discuss practical strategies to overcome barriers to hepatitis B virus (HBV) care, including:

Overcoming health insurance navigation
Improving access to HBV care in immigrant communities
Dispelling HBV myths and stigma
Solutions to language barriers
Community-based interventions

Presenters:

Patricia D. Jones, MD, MSCR
Associate Professor of Clinical Medicine
Director of Clinical Operations-Hepatology
Division of Digestive Health and Liver Diseases
Department of Medicine
University of Miami Miller School of Medicine
Sylvester Comprehensive Cancer Center
Miami, Florida

Mindie H. Nguyen, MD, MAS, AGAF, FAASLD
Professor of Medicine (GI & Hepatology,
Liver Transplant)
Professor of Epidemiology & Population Health
(by Courtesy)
Director of Hepatology Clerkship
Faculty Search LENS Advocates,
Stanford Department of Medicine
Faculty Fellow, Stanford Center for Innovation
in Global Health
Member, Stanford Cancer Institute, Maternal &
Child Health Research Institute, & Stanford Bio-C
Stanford, California
Past Chair: HBV SIG, The American Association for the Study of Liver Diseases (AASLD)
28th President: The International Association for the Study of the Liver (IASL)

Jennifer Wild, MS, RN, OCN
Clinical Nurse – GI Medical Oncology
UCSF Cancer Center
San Francsico, California

Link to full program:
https://bit.ly/4j973TN

Downloadable slides:
https://bit.ly/3WQkIWl

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Best Practices for Inpatient Management of Severe COVID-19

Mon, 10 Mar 2025 14:17:40 +0000

In this episode, Stephen Cantrill, MD, FACEP; Rajesh T. Gandhi, MD; and Payal K. Patel, MD, MPH, FIDSA, discuss:

Workup of COVID-19 in the emergency department
Methods of COVID-19 risk stratification
Treatment recommendations for people with severe COVID-19, including how to effectively use antiviral therapy, dexamethasone, and other immunomodulators[CC1] in this population
A detailed patient case to illustrate key takeaways

Presenters:

Rajesh T. Gandhi, MD
Massachusetts General Hospital
Professor of Medicine
Harvard Medical School
Boston, Massachusetts

Payal K. Patel, MD, MPH, FIDSA
Systemwide Director of Antimicrobial Stewardship
Associate Professor, Division of Infectious Diseases
Intermountain Health
Salt Lake City, Utah

Link to full program:
https://bit.ly/4gu2gcU

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

COVID-19 in the EU: Inpatient Treatment of Mild to Moderate COVID-19 in Patients Who Are Immunocompromised

Thu, 6 Feb 2025 18:21:52 +0000

In this episode, Martin Witzenrath, MD, FERS, and Michele Bartoletti, MD, PhD, discuss the management of mild to moderate COVID-19 in patients who are immunocompromised, including:

Initial workup, which may include laboratory tests and/or imaging
Latest data on the use of remdesivir or nirmatrelvir plus ritonavir for mild to moderate COVID-19, including considerations for drug–drug interactions

Presenters:

Martin Witzenrath, MD, FERS
Medical Director
Charite Centrum 12
Internal Medicine & Dermatology
Professor and Chair for Respiratory Medicine and Critical Care
Department of Infectious Disease, Respiratory Medicine and Critical Care
Charite Campus Mitte/Campus Virchow Klinikum/Campus Benjamin Franklin
Charite – University of Berlin
Berlin, Germany

Link to full program:
https://bit.ly/4gu2gcU

Downloadable slides:
https://bit.ly/3CGlDBS

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Defining Best Practices in HBV Care

Wed, 5 Feb 2025 17:48:27 +0000

In this episode, Patricia D. Jones, MD, MSCR; Mindie H. Nguyen, MD, MAS, AGAF, FAASLD; and patient advocate, Jennifer Wild, MS, RN, OCN, discuss best practices in hepatitis B virus (HBV) care, including:

2023 CDC HBV screening recommendations
Summary of guideline recommendations for hepatitis delta virus (HDV) screening
Use of HDV reflex testing to avoid loss to follow-up
2024 WHO HBV treatment recommendations, including recommendations for pregnant persons

Presenters:

Past Chair: HBV SIG, The American Association for the Study of Liver Diseases (AASLD)

28th President: The International Association for the Study of the Liver (IASL)

Jennifer Wild, MS, RN, OCN
Clinical Nurse – GI Medical Oncology
UCSF Cancer Center
San Francsico, California

Link to full program:
https://bit.ly/4j973TN

Downloadable slides:
https://bit.ly/3WQkIWl

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

COVID-19 in the EU: Current Trends and Risk Factors for Severe COVID-19 Progression

Wed, 5 Feb 2025 17:02:23 +0000

In this episode, Cristina Mussini, MD, Martin Witzenrath, MD, FERS, and Michele Bartoletti, MD, PhD, discuss:

Current SARS-CoV-2 trends in the EU
Risk factors for severe COVID-19 outcomes, including the spectrum of risk based on immune system status
Factors that may affect vaccine efficacy in chronic lymphocytic leukemia and other lymphoid malignancies
Considerations for determining people at high risk for COVID-19 progression

Presenters:

Cristina Mussini, MD
Full Professor of Infectious Diseases
Division of Infectious Diseases
University of Modena and Reggio Emilia
Modena, Italy

Martin Witzenrath, MD, FERS
Medical Director
Charite Centrum 12
Internal Medicine & Dermatology
Professor and Chair for Respiratory Medicine and Critical Care
Department of Infectious Disease, Respiratory Medicine and Critical Care
Charite Campus Mitte/Campus Virchow Klinikum/Campus Benjamin Franklin
Charite – University of Berlin
Berlin, Germany

Link to full program:
https://bit.ly/4gu2gcU

Downloadable slides:
https://bit.ly/42IlpEL

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Simplified HCV Care in Sexual and Reproductive Health Clinics

Wed, 8 Jan 2025 05:00:00 +0000

In this episode, Tzu-Hao (Howard) Lee, MD; Tatyana Kushner, MD, MSCE; and patient advocate Andrew Reynolds discuss hepatitis C virus (HCV) care in men who have sex with men and pregnant people, including:

HCV disease burden in the United States
Screening recommendations
Strategies to overcome barriers to HCV screening
Treatment recommendations, including simplified treatment guidance and considerations for pregnant people
Strategies to improve treatment uptake

Presenters:

Tzu-Hao (Howard) Lee, MD
Assistant Professor
Section of Gastroenterology and Hepatology, Department of Medicine
Division of Abdominal Transplant, Department of Surgery
Baylor College of Medicine
Houston, Texas

Tatyana Kushner, MD, MSCE
Associate Professor
Division of Gastroenterology/Hepatology
Department of Obstetrics & Gynecology
Weill Cornell Medicine
New York, New York

Andrew Reynolds
Director, Health of People Who Use Drugs
San Francisco AIDS Foundation
San Francisco, California

To access all of our new podcast episodes, subscribe to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify. 

Link to full program:
https://bit.ly/4j973TN

Downloadable slides:
https://bit.ly/4gXuBcu

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Key PBC Studies From AASLD 2024

support@deceraclinical.com (Sonal Kumar MD MPH) — Tue, 7 Jan 2025 19:15:00 +0000

In this episode, Sonal Kumar, MD, MPH, discusses key findings from primary biliary cholangitis (PBC) studies presented at AASLD 2024, including:

ELATIVE, a phase III trial of elafibranor for PBC
RESPONSE, a phase III trial of seladelpar for PBC
ASSURE, another phase III trial of seladelpar for PBC

Presenter:
Sonal Kumar, MD, MPH
Director, Clinical Gastroenterology and Hepatology
Assistant Professor of Medicine
Weill Cornell Medical College
New York, New York

Link to full program:
https://bit.ly/41tvSDu

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Understanding Current Trends and Risk Factors for Progression to Severe COVID-19

Thu, 2 Jan 2025 15:45:11 +0000

Listen in as Stephen Cantrill, MD, FACEP; Rajesh T. Gandhi, MD; and Payal K. Patel, MD, MPH, FIDSA, discuss current trends in and risk factors for progression to severe COVID-19, including for those for whom COVID-19 is not their primary concern when presenting to the emergency department (ED). Key topics of discussion include:

How to complete a comprehensive patient workup in the ED
Considerations regarding pulse oximetry
Risk stratification—what places patients at higher risk of severe disease?
A detailed patient case to illustrate key takeaways

Presenters:

Rajesh T. Gandhi, MD
Massachusetts General Hospital
Professor of Medicine
Harvard Medical School
Boston, Massachusetts

Payal K. Patel, MD, MPH, FIDSA
Systemwide Director of Antimicrobial Stewardship
Associate Professor, Division of Infectious Diseases
Intermountain Health
Salt Lake City, Utah

Link to full program:
https://bit.ly/4fs7Hcb

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Simplified HCV Screening and Care in People Who Use Drugs

Mon, 23 Dec 2024 16:24:07 +0000

In this episode, Stacey B. Trooskin, MD, PhD, MPH, Mark S. Sulkowski, MD, FIDSA, FAASLD, and Ronni Marks discuss hepatitis C virus (HCV) screening and treatment, focusing on people who use drugs, and highlight the following topics:

Screening recommendations
Strategies to improve HCV screening
HCV testing
Treatment goals
Strategies to improve HCV treatment uptake

Presenters:

Stacey B. Trooskin, MD, PhD, MPH
Executive Medical Officer
Mazzoni Center
Faculty, University of Pennsylvania
Perelman School of Medicine
Philadelphia, Pennsylvania

Mark S. Sulkowski, MD, FIDSA, FAASLD
Professor of Medicine
Director, Division of Infectious Diseases Johns Hopkins Bayview Medical Center
Johns Hopkins University School of Medicine
Baltimore, Maryland

Ronni Marks
Founder/Director, The Hepatitis C Mentor and Support Group (HCMSG)
Patient Advocate
New York, New York

Link to full program:
https://bit.ly/4grbwPT

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Inpatient Treatment for Mild to Moderate COVID-19

Thu, 19 Dec 2024 17:17:21 +0000

Listen in as Stephen Cantrill, MD, FACEP; Rajesh T. Gandhi, MD; and Payal K. Patel, MD, MPH, FIDSA, discuss best practices in treating patients hospitalized with mild to moderate COVID-19, including:

Current guidelines from the Infectious Diseases Society of America and National Institutes of Health
How to optimize therapy selection based on patient risk factors, including key data supporting best practices
A detailed patient case to illustrate key takeaways

Presenters:

Rajesh T. Gandhi, MD
Massachusetts General Hospital
Professor of Medicine
Harvard Medical School
Boston, Massachusetts

Payal K. Patel, MD, MPH, FIDSA
Systemwide Director of Antimicrobial Stewardship
Associate Professor, Division of Infectious Diseases
Intermountain Health
Salt Lake City, Utah

Link to full program:
https://bit.ly/4fs7Hcb

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Emerging Therapies for Pruritus in PBC

Wed, 18 Dec 2024 17:00:56 +0000

Clinical gaps in the treatment of pruritus in primary biliary cholangitis (PBC) remain. In this episode, taken from a recent symposium, Marlyn J. Mayo, MD; Stuart C. Gordon, MD; and Pam Rivard, RN, a person living with PBC, discuss emerging therapies currently in clinical trials for the management of this disease that can dramatically affect patients’ quality of life.

Listen as they discuss:

Gaps in current management
Patient perspectives: why we should not dismiss itching as an underlying psychologic problem
PPAR agonists and how they affect pruritus
BEZURSO and FITCH
ELATIVE
ENHANCE and RESPONSE
IBATs (inhibitors of bile acid transport)
GLIMMER
Common questions

Presenters:

Marlyn J. Mayo, MD
Professor of Internal Medicine
Division of Digestive & Liver Diseases
UT Southwestern Medical Center
Dallas, Texas

Stuart C. Gordon, MD
Professor of Medicine
Wayne State University School of Medicine
Director, Division of Hepatology
Henry Ford Health
Detroit, Michigan

Pam Rivard, RN
Person living with PBC

Link to full program:
https://bit.ly/3Dnfb2E

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Clinical Management of Pruritus in PBC

Wed, 18 Dec 2024 16:10:55 +0000

Although there is currently no FDA-approved treatment for pruritus in primary biliary cholangitis (PBC), symptoms can be mitigated with nonpharmacologic or pharmacologic agents. In this episode, Marlyn J. Mayo, MD; Stuart C. Gordon, MD; and Pam Rivard, RN, a person living with PBC, discuss the clinical management of pruritus in PBC, including:

Pruritus assessment tools
Optimal use of tools, including frequency of assessment
Current management of pruritus
Nonpharmacologic interventions
Pharmacologic agents
Strategies to optimize assessment and management of pruritus
Collaborative care
Development of a treatment plan
Ongoing assessment and adjustment of therapy
Resources and support for patients

Presenters:

Marlyn J. Mayo, MD
Professor of Internal Medicine
Division of Digestive & Liver Diseases
UT Southwestern Medical Center
Dallas, Texas

Stuart C. Gordon, MD
Professor of Medicine
Wayne State University School of Medicine
Director, Division of Hepatology
Henry Ford Health
Detroit, Michigan

Pam Rivard, RN
Person living with PBC

Link to full program:
https://bit.ly/3Dnfb2E

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Living With Pruritus in PBC: A Patient Perspective

Wed, 18 Dec 2024 15:03:52 +0000

In this episode, Marlyn J. Mayo, MD; Stuart C. Gordon, MD; and Pam Rivard, RN, a person living with primary biliary cholangitis (PBC), discuss the burden of pruritus in PBC and the impact it has on quality of life, including both physical and mental health, from a patient’s perspective.

Presenters:

Marlyn J. Mayo, MD
Professor of Internal Medicine
Division of Digestive & Liver Diseases
UT Southwestern Medical Center
Dallas, Texas

Stuart C. Gordon, MD
Professor of Medicine
Wayne State University School of Medicine
Director, Division of Hepatology
Henry Ford Health
Detroit, Michigan

Pam Rivard, RN
Person living with PBC

Link to full program:
https://bit.ly/4gDGDaB

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CCO Independent Conference Coverage of IDWeek and Glasgow 2024

support@deceraclinical.com (Jean-Michel Molina MD PhD, Joseph J. Eron MD) — Tue, 17 Dec 2024 14:57:50 +0000

In this episode, Jean-Michel Molina, MD, PhD, and Joseph J. Eron, Jr., MD, discuss results from key clinical trials on HIV prevention and treatment as well as sexually transmitted infection (STI) prevention presented at IDWeek and Glasgow 2024, including:

PURPOSE 1 and 2 comparing lenacapavir injection vs oral TDF/FTC
TRIO Health Cohort and OPERA examining long-acting cabotegravir as PrEP
DOLCE comparing DTG/3TC as first-line therapy in treatment-naive patients with HIV
PRIDOX evaluating the use of DoxyPEP on STI incidence in men who have sex with men on PrEP

Presenters:

Jean-Michel Molina, MD, PhD
Professor of Infectious Diseases
University of Paris Cité
Head of the Department of Infectious Diseases
Hospital Saint-Louis and lariboisière
Paris, France

Joseph J. Eron, Jr., MD
Professor of Medicine, School of Medicine
Herman and Louise Smith Distinguished Professor
Chief, Division of Infectious Diseases
Director, Clinical Core, UNC Center for AIDS Research
Adjunct Professor of Epidemiology, Gillings School of Global Public Health
University of North Carolina at Chapel Hill
Chapel Hill, North Carolina

Link to full program:
https://bit.ly/3BBaZvJ

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Recent Advances in PBC Management

support@deceraclinical.com (Christopher L. Bowlus MD) — Fri, 13 Dec 2024 17:50:22 +0000

In this episode, Christopher L. Bowlus, MD, discusses recent advances in the management of primary biliary cholangitis (PBC), including:

Treatment goals
Use of PPAR agonists for the treatment of PBC
Clinical trial results for elafibranor (ELATIVE), seladelpar (RESPONSE), and bezafibrate (BEZURSO)

Presenter:

Christopher L. Bowlus, MD
Lena Valente Professor and Chief
Division of Gastroenterology and Hepatology
University of California Davis School of Medicine
Sacramento, California

Link to full program:
https://bit.ly/41tvSDu

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Be an Ally: Navigating the Healthcare System as a Transgender Individual With HIV

Wed, 13 Nov 2024 18:14:55 +0000

In this episode, a transfemme nonbinary individual living with HIV shares her experience navigating the healthcare system, alongside her infectious disease physician, Michelle D. Collins-Ogle, MD, FAAP, FPIDS, AAHIVS. Hear them discuss key considerations when caring for gender-diverse individuals, including:

Understanding how people are more than just a diagnosis
Prioritizing individuals’ needs and providing whole-person care using shared decision-making
Strategies to make an environment more affirming and welcoming
How to be an ally to transgender individuals
- Listen to the individual in front of you
- Hear what they’re telling you
- Make sure they are being affirmed and seen

Link to the full program:
https://bit.ly/3AAOGpv

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Key HIV Studies Influencing My Practice Following HIVR4P 2024—Drs . Linda-Gail Bekker and Meredith Clement

Wed, 30 Oct 2024 04:00:00 +0000

In this rapid webinar, Meredith E. Clement, MD, and Linda-Gail Bekker, MBChB, DTMH, DCH, FCP(SA), PhD, provide an overview of important topics and studies presented at HIVR4P 2024, including:

Expanding PrEP options based on results from PURPOSE 2, IMPOWER-22, IMPOWER-24, IPM 054, MTN-025/HOPE OLE, CATALYST, and the HPTN 084 substudy
Implementing injectable PrEP based on results from PEPFAR, the USAID DISCOVER-Health LA CAB Demonstration Project in Zambia, and the LA CAB PrEP Rapid Start Model in Public Health Clinics
Improving PrEP uptake based on results from SPrEP and HPTN 091

Presenters:

Meredith E. Clement, MD
Associate Professor
Infectious Diseases
Louisiana State University Health Sciences Center
New Orleans, Louisiana

Linda-Gail Bekker, MBChB, DTMH, DCH, FCP(SA), PhD
Director and Professor, The Desmond Tutu HIV Centre, UCT
CEO, The Desmond Tutu Health Foundation
Cape Town, South Africa

To access all of our new podcast episodes, subscribe to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify. 

Link to full program:
https://bit.ly/3NJIDSA

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Be an HPV Vaccine Champion: Reaching Underserved Populations

support@deceraclinical.com (Rebekah Fenton MD MPH, Sharon G. Humiston MD MPH) — Tue, 29 Oct 2024 15:33:30 +0000

Listen in as Rebekah Fenton, MD, MPH, and Sharon G. Humiston, MD, MPH, discuss strategies to achieve health equity in HPV vaccination, including:

Trends among males vs females
Messaging considerations for those from diverse populations (eg, LGTBQ+ and rural communities)
How healthcare professionals can address barriers to care

Then, hear answers from the experts to frequently asked questions regarding HPV vaccination recommendations, timing, and example case studies.

Presenters:
Rebekah Fenton, MD, MPH
Adolescent Medicine Physician
Alivio Medical Center
Chicago, Illinois

Sharon G. Humiston, MD, MPH
Director for Research
Associate Editor of IZ-Express
Immunize.org
Rochester, New York

To access all of our new podcast episodes, subscribe to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify. 

Follow along with the slides:
https://bit.ly/4flDxYb

Link to full program:
https://bit.ly/4f06tW4

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Key HIV Studies Influencing My Practice Following HIVR4P 2024—Drs . Linda-Gail Bekker and Meredith Clement

Mon, 28 Oct 2024 17:16:26 +0000

In this rapid webinar, Meredith E. Clement, MD, and Linda-Gail Bekker, MBChB, DTMH, DCH, FCP(SA), PhD, provide an overview of important topics and studies presented at HIVR4P 2024, including:

Expanding PrEP options based on results from PURPOSE 2, IMPOWER-22, IMPOWER-24, IPM 054, MTN-025/HOPE OLE, CATALYST, and the HPTN 084 substudy
Implementing injectable PrEP based on results from PEPFAR, the USAID DISCOVER-Health LA CAB Demonstration Project in Zambia, and the LA CAB PrEP Rapid Start Model in Public Health Clinics
Improving PrEP uptake based on results from SPrEP and HPTN 091

Presenters:

Meredith E. Clement, MD
Associate Professor
Infectious Diseases
Louisiana State University Health Sciences Center
New Orleans, Louisiana

Linda-Gail Bekker, MBChB, DTMH, DCH, FCP(SA), PhD
Director and Professor, The Desmond Tutu HIV Centre, UCT
CEO, The Desmond Tutu Health Foundation
Cape Town, South Africa

To access all of our new podcast episodes, subscribe to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify. 

Link to full program:
https://bit.ly/3NJIDSA

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Strategies to Improve HPV Vaccine Uptake: Effective Vaccine Messaging

support@deceraclinical.com (Rebekah Fenton MD MPH, Sharon G. Humiston MD MPH) — Mon, 28 Oct 2024 16:29:22 +0000

Listen in as Rebekah Fenton, MD, MPH, and Sharon G. Humiston, MD, MPH, discuss strategies to improve your messaging techniques with the HPV vaccine, including:

Persisting in vaccine recommendation after initial refusal
Educating patients and their families together
Ensuring staff are trained to correctly answer questions
Knowing when interested patients in your state can consent to vaccination without needing parental consent

Presenters:
Rebekah Fenton, MD, MPH
Adolescent Medicine Physician
Alivio Medical Center
Chicago, Illinois

Sharon G. Humiston, MD, MPH
Director for Research
Associate Editor of IZ-Express
Immunize.org
Rochester, New York

To access all of our new podcast episodes, subscribe to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify. 

Follow along with the slides:
https://bit.ly/4flDxYb

Link to full program:
https://bit.ly/4f06tW4

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The True Burden of HPV Infection

support@deceraclinical.com (Sharon G. Humiston MD MPH) — Mon, 28 Oct 2024 16:11:58 +0000

Listen in as Sharon G. Humiston, MD, MPH, discusses current trends in HPV, including:

Incidence and prevalence trends in the US
Sex-related features of HPV-attributable cancers
How HPV vaccination uptake can prevent certain types of cancer
Current guidelines and recommendations for HPV vaccination

Presenter:
Sharon G. Humiston, MD, MPH
Director for Research
Associate Editor of IZ-Express
Immunize.org
Rochester, New York

To access all of our new podcast episodes, subscribe to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify. 

Follow along with the slides:
https://bit.ly/4flDxYb

Link to full program:
https://bit.ly/4f06tW4

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Making Addiction Care an Integral Part of HIV Care

support@deceraclinical.com (Kathleen Page MD, Glenn J. Treisman MD PhD) — Tue, 8 Oct 2024 21:00:00 +0000

In this episode, Kathleen Page, MD, and Glenn J. Treisman, MD, PhD, discuss the interplay between addiction and HIV. Learn as they share their approaches to reframing the conversation about addiction and overcoming barriers to effective addiction care for people living with HIV.

Presenters:

Kathleen Page, MD
Professor
Infectious Diseases
Johns Hopkins School of Medicine
Baltimore, Maryland

Glenn J. Treisman, MD, PhD
Eugene Meyer III Professor of Psychiatry and Medicine
Johns Hopkins University School of Medicine
Baltimore, Maryland

Downloadable slides:
https://bit.ly/3TR3OVV

Program:
https://bit.ly/3WB2VCO

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Persisting in HIV Care: Considerations for People With Substance Use Disorders

support@deceraclinical.com (Alexander Wong MD FRCPC) — Fri, 13 Sep 2024 19:35:00 +0000

In this episode, Alexander Wong, MD, FRCPC, discusses how to optimize treatment and engagement in care for individuals with HIV and substance use disorder, including:

Barriers to care for persons with substance use disorder
Colocating HIV and other services (eg, addiction care medicine, social services)
Leveraging a multidisciplinary approach to care
Integrating a low-barrier model to foster an environment of open discussion
Best practices for opioid agonist therapy implementation
Considerations for cultural dynamics to provide personalized treatment plans
Importance of supporting his team members

Presenter

Alexander Wong, MD, FRCPC
Associate Professor
Division of Infectious Diseases
Department of Medicine
University of Saskatchewan
Regina, Saskatchewan, Canada

Link to full program:
https://bit.ly/3xicSeF

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Integrating New Data From AIDS 2024: Pharmacist Perspectives

Fri, 30 Aug 2024 18:49:10 +0000

In this episode, Jennifer Cocohoba, PharmD, AAHIVP, and David Koren, PharmD, MPH, AAHIVP, FIDSA, cover the most impactful LA ART and LA PrEP clinical studies presented at AIDS 2024, including:

The PURPOSE 1 study of twice-yearly lenacapavir injections vs daily oral tenofovir as PrEP in cisgender women
An open-label extension of HPTN 084 evaluating LA CAB safety during pregnancy
48-week data from the IMPAACT 2017/MOCHA study of LA CAB + RPV in adolescents with HIV
A substudy of FLAIR evaluating the efficacy, safety, and tolerability of SC self-administration of LA CAB + RPV

Presenters:

Jennifer Cocohoba, PharmD, AAHIVP
Professor of Clinical Pharmacy
Department of Clinical Pharmacy
University of California San Francisco School of Pharmacy
San Francisco, California

David Koren, PharmD, MPH, AAHIVP, FIDSA
Adjunct Clinical Professor
Temple University School of Pharmacy
Clinical Pharmacist Specialist
Temple University Health System
Philadelphia, Pennsylvania

To access all of our new podcast episodes, subscribe to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify. 

See the full program here.

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How to Make PTSD and Trauma Care an Integral Part of HIV Care

Tue, 27 Aug 2024 04:00:00 +0000

In this episode, Tristan J. Barber, MA, MD, FRCP, and Glenn J. Treisman, MD, PhD, discuss the importance of screening, diagnosing, and treating PTSD in people with HIV. They illustrate their discussion through a patient case and provide strategies for accomplishing this, sharing their own experiences and approaches to thinking about PTSD, structuring appointments, and integrating care.

Presenters:

Tristan J. Barber, MA, MD, FRCP
Consultant in HIV Medicine
Royal Free London NHS Foundation Trust
Honorary Associate Professor
Institute for Global Health
University College London
London, United Kingdom

Glenn J. Treisman, MD, PhD
Eugene Meyer III Professor of Psychiatry and Medicine
Johns Hopkins University School of Medicine
Baltimore, Maryland

Downloadable slides:
https://bit.ly/4dBu929

Program:
https://bit.ly/3WB2VCO

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Be an Ally: How to Improve Care for Transgender Persons Living With HIV

support@deceraclinical.com (Coleen F. Kelley MD MPH, Kritima Jemma Samitpol) — Thu, 22 Aug 2024 19:16:53 +0000

In this episode, Colleen F. Kelley, MD, MPH, and Jemma Samitpol discuss key considerations to improve the patient experience among transgender persons with HIV, including:

Unique circumstances faced by transgender people trying to access HIV care (eg, stigma, discrimination)
Best practices to improve access and linkage to HIV care
Ways to integrate gender-affirming care into HIV care
Creating a welcoming and inclusive environment
Offering same-day HIV treatment
Addressing potential drug–drug interactions with gender-affirming hormone therapy (GAHT), including ART and natural remedies
Understanding and communicating expectations of GAHT (eg, treatment response, timing of effects)
Providing information on the safety of gender-affirming surgeries
Importance of providing person-centered care (eg, mental health, substance abuse, housing, harm reduction)
Strategies on how to promote a gender-affirming environment (eg, wearing pronoun buttons, staff training)
Consequences to the lack of gender recognition laws
How to “be an ally” for transgender people with HIV

Presenters

Colleen F. Kelley, MD, MPH
Professor of Medicine
Division of Infectious Diseases
Department of Medicine
Co-Director, Emory Center for AIDS Research
Associated Dean for Research, Emory at Grady
Emory University School of Medicine
Atlanta, Georgia

Kritima Jemma Samitpol
Tangerine Clinic Supervisor
Institute of HIV Research and Innovation
Bangkok, Thailand

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast channel on Apple Podcasts, Google Podcasts, or Spotify.

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Considering Long-acting ART With Viremia and Past Adherence Challenges

support@deceraclinical.com (Aadia I. Rana MD, Laurence Slama MD PhD) — Thu, 22 Aug 2024 14:29:12 +0000

In this episode featuring faculty from the United States and Europe, Aadia I. Rana, MD, and Laurence Slama, MD, PhD, discuss the subtleties of deciding among HIV treatment options in people with adherence challenges.

Listen as they debate the potential risks and benefits of long-acting ART in this population, considerations for people with viremia or resistance, recommendations concerning proviral DNA genotyping, and how to interpret guidelines and provide truly patient-centered care.

Presenters

Aadia I. Rana, MD
Professor of Medicine
Division of Infectious Diseases
University of Alabama at Birmingham Heersink School of Medicine
Birmingham, Alabama

Laurence Slama, MD, PhD
Doctor
Department of Infectious Diseases
Hôtel Dieu University Hospital
University Paris Cité
Paris, France

Follow along with the slides here.

See the full program here.

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast channel on Apple Podcasts, Google Podcasts, or Spotify.

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Optimizing ART With Novel HIV Agents

support@deceraclinical.com (Gregory Huhn MD) — Fri, 16 Aug 2024 18:43:54 +0000

In this episode, Gregory Huhn, MD, MPHTM, presents a case study of a person with a long HIV treatment history, exploring when and how to consider agents with novel mechanisms of action.

Listen as he discusses:

The importance of engaging with patients to understand their perspectives and improve their satisfaction with their HIV care
Options in people with multiclass resistance
Studies of agents with novel mechanisms of action:
- BRIGHTE (fostemsavir)
- TMB-301/-311 (ibalizumab)
- CAPELLA (lenacapavir)

Faculty

Gregory Huhn, MD, MPHTM,
Interim Chief, Division of Infectious Diseases
Senior Director of HIV Services
Cook County HIV Integrated Programs
Interim Medical Director, The RMR CORE Center
Professor, Division of Infectious Diseases
Rush University Medical Center
Chicago, Illinois

Follow along with the slides.
https://bit.ly/4fHmxg5

Get access to all of our new podcast episodes. Subscribe to the CCO Infectious Disease podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Making Space for HIV Care: Starting in Care

support@deceraclinical.com (Yvonne Gilleece MB BCh BAO FRCP) — Fri, 16 Aug 2024 16:41:36 +0000

In this episode, Yvonne Gilleece, MB BCh, BAO, FRCP, uses a case study to illustrate why giving people space and time to engage in HIV care on their terms is key to overcoming potential shame and stigma.

She discusses how people can be very vulnerable when engaging in HIV care, and trauma-informed care can help address these vulnerabilities in a safe, respectful way. Listen as she gives her perspectives on:

Trauma-informed care
Overcoming stigma and shame
Staying in care

Presenter:
Yvonne Gilleece, MB BCh, BAO, FRCP
Honorary Clinical Professor and Consultant in HIV Medicine & Sexual Health
Brighton & Sussex Medical School and University Hospitals Sussex NHS Foundation Trust
Chair of the British HIV Association
Lead for HIV & Women
Lead for HIV & Hepatitis
Brighton, United Kingdom

Content based on an online CME program supported by an educational grant from Gilead Sciences, Inc.

Link to full program:
https://bit.ly/3xicSeF

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Keeping Up With HBV Care: Sharing Session 4

Thu, 15 Aug 2024 13:50:23 +0000

In this episode, George Lau, MD, FRCP (Edin, Lond), FHKAM (Med), FHKCP, FAASLD, MBBS (HKU), and a patient discuss opportunities to optimize care for people living with hepatitis B virus (HBV), including:

Consequences to poor adherence to antiviral therapy
Strategies to promote medication adherence (eg, patient education, setting up routines)
The role of routine monitoring to prevent complications related to HBV such as hepatocellular carcinoma

Presenter:

George Lau, MD, FRCP (Edin, Lond), FHKAM (Med), FHKCP, FAASLD, MBBS (HKU)
Specialist in Gastroenterology & Hepatology
Chairman and Senior Consultant in Gastroenterology and Hepatology
Humanity and Health Medical Group
Hong Kong, China

Content based on an online CME program supported by an independent educational grant from Gilead Sciences, Inc.

Link to full program:
https://bit.ly/49TuZ8U

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Optimizing Oral ART

support@deceraclinical.com (Gregory Huhn MD) — Wed, 14 Aug 2024 13:04:49 +0000

In this episode, Gregory Huhn, MD, presents a case study exploring how to optimize oral ART for a person with a long history of different ART regimens.

Listen as he discusses:

Reasons to consider regimen optimization in the setting of viral suppression
Evidence for INSTIs in the setting of resistance
Data on when 2-drug regimens and long-acting regimens may or may not be good options

Faculty

Gregory Huhn, MD
Interim Chief, Division of Infectious Diseases
Senior Director of HIV Services
Cook County HIV Integrated Programs
Interim Medical Director, The RMR CORE Center
Professor, Division of Infectious Diseases
Rush University Medical Center
Chicago, IL

Follow along with the slides.
https://bit.ly/4fHmxg5

Get access to all of our new podcast episodes, subscribe to the CCO Infectious Disease podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Beyond Viral Suppression—Pharmacist Perspectives

Fri, 9 Aug 2024 18:20:00 +0000

In this episode, Lucas Hill, PharmD, AAHIVP, BCACP, and Bernadette Jakeman, PharmD, PhC, BCPS, AAHIVP,discuss what pharmacists need to know to provide high-quality HIV care beyond viral suppression, including treatment strategies and tips for addressing and improving patients’ quality of life.

Listen as they discuss:

Reasons to consider regimen optimization in the setting of viral suppression
Evidence that LA ART may reduce internalized stigma
DHHS recommendations on proviral DNA genotyping

Faculty

Lucas Hill, PharmD, AAHIVP, BCACP
HIV Pharmacist Specialist
UC San Diego Owen Clinic
Assistant Clinical Professor
UC San Diego Skaggs School of Pharmacy
San Diego, California

Bernadette Jakeman, PharmD, PhC, BCPS, AAHIVP|
Associate Clinical Professor
Department of Pharmacy Practice and Administrative Sciences
University of New Mexico College of Pharmacy
Albuquerque, New Mexico

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Optimizing PBC Pruritus Care in the Clinic

Mon, 29 Jul 2024 15:02:35 +0000

In this episode, Stuart C. Gordon, MD, FACP, FACG, AGAF, FAASLD; Marlyn J. Mayo, MD; and Brenda Remo discuss strategies for optimizing PBC pruritus care in the clinic setting.

Listen to their conversation on how important it is to ask patients about their pruritus, validate their symptoms and feelings, and offer treatment options framed with realistic expectations.

Presenters:

Stuart C. Gordon, MD, FACP, FACG, AGAF, FAASLD
Professor of Medicine
Wayne State University School of Medicine
Director, Division of Hepatology
Henry Ford Health
Detroit, Michigan

Marlyn J. Mayo, MD
Professor of Internal Medicine
Division of Digestive & Liver Diseases
University of Texas Southwestern
Dallas, Texas

Brenda Remo
Person living with PBC

Downloadable slides:
https://bit.ly/3LHHiuf

Program:
https://bit.ly/4fBLQ3l

To get access to all of our new podcast episodes, subscribe to the CCO podcast channels on Apple Podcasts, Google Podcasts, or Spotify.

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The Patient Experience With Cholestatic Pruritus in PBC

Mon, 29 Jul 2024 14:48:14 +0000

In this episode, Stuart C. Gordon, MD, FACP, FACG, AGAF, FAASLD; Marlyn J. Mayo, MD; and Brenda Remo discuss the patient experience with cholestatic pruritus in PBC.

Listen to their conversation on how people describe the experience of cholestatic pruritus, the extent to which pruritus negatively affects quality of life, and the importance of educating healthcare professionals on this important symptom of PBC.

Presenters:

Stuart C. Gordon, MD, FACP, FACG, AGAF, FAASLD
Professor of Medicine
Wayne State University School of Medicine
Director, Division of Hepatology
Henry Ford Health
Detroit, Michigan

Marlyn J. Mayo, MD
Professor of Internal Medicine
Division of Digestive & Liver Diseases
University of Texas Southwestern
Dallas, Texas

Brenda Remo
Person living with PBC

Downloadable slides:
https://bit.ly/3LHHiuf

Program:
https://bit.ly/4fBLQ3l

To get access to all of our new podcast episodes, subscribe to the CCO podcast channels on Apple Podcasts, Google Podcasts, or Spotify.

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How to Make Depression Care an Integral Part of HIV Care

support@deceraclinical.com (Glenn J. Treisman MD PhD, Bradley N. Gaynes MD MPH) — Wed, 24 Jul 2024 20:28:36 +0000

In this episode, Bradley N. Gaynes, MD, MPH, and Glenn J. Treisman, MD, PhD, discuss the importance of screening, diagnosing, and treating depression in people living with HIV. They illustrate their discussion through a patient case and provide strategies for accomplishing this, including creation of a virtual network and employment of measurement-based care.

Presenters:

Bradley N. Gaynes, MD, MPH
Ray M. Hayworth, MD and Family Distinguished Professor
Professor of Psychiatry and Epidemiology
Director, Division of Global Mental Health
Co-Director, Physician Scientist Training Program
Department of Psychiatry
University of North Carolina School of Medicine
Chapel Hill, North Carolina

Glenn J. Treisman, MD, PhD
Eugene Meyer III Professor of Psychiatry and Medicine
Johns Hopkins University School of Medicine
Baltimore, Maryland

Downloadable slides:
https://bit.ly/3YgqqSO

Program:
https://bit.ly/3WB2VCO

To get access to all of our new infectious disease podcast episodes, subscribe to the CCO infectious disease podcast channel on Apple Podcasts, Google Podcasts, or Spotify.

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Managing Weight Gain on ART

support@deceraclinical.com (Decera Clinical Education) — Thu, 27 Jun 2024 04:00:00 +0000

In this episode, Cristina Mussini, MD,and William R. Short, MD, MPH, FIDSA,discuss the potential role of ART in weight change among people living with HIV.

Listen to their conversation on whether ART switch can lead to weight loss after weight gain and how to counsel people living with HIV on weight loss options, including lifestyle modifications and nonpharmacologic methods.

Presenters

Cristina Mussini, MD
Director of Infectious Diseases Clinics
Professor of Infectious Diseases
University of Modena School of Medicine
Modena, Italy

William R. Short, MD, MPH, FIDSA
Associate Director of the
HIV Clinical Trials Unit
Associate Professor of Medicine
Division of Infectious Diseases
Perelman School of Medicine
University of Pennsylvania
Philadelphia, Pennsylvania

Follow along with the slides here.
https://bit.ly/3RLdrET

See the full program here.
https://bit.ly/450Ql2x

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast channel on Apple Podcasts, Google Podcasts, or Spotify.

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A Triumphant Return: Welcoming People Back to HIV Care

support@deceraclinical.com (Linda-Gail Bekker MBChB DTM&H DCH FCP(SA) PhD) — Mon, 17 Jun 2024 04:00:00 +0000

In this episode, Linda-Gail Bekker, MBChB, DTM&H, DCH, FCP(SA), PhD, uses a case study to illustrate why patients living with HIV may disengage with their care and how best to reengage them once they present at the clinic, including discussion of:

The valid reasons patients have for disengaging with their HIV care
Why the return to care should be celebrated
How to support people living with HIV as they reengage in care
How to prevent future loss to follow-up

Presenter:
Linda-Gail Bekker, MBChB, DTM&H, DCH, FCP(SA), PhD
CEO, Desmond Tutu Health Foundation
Director, Desmond Tutu HIV Centre
Professor of Medicine
Faculty of Health Sciences
University of Cape Town
Cape Town, South Africa

Content based on an online CME program supported by an educational grant from Gilead Sciences, Inc.

Link to full program:
https://bit.ly/3xicSeF

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts or Spotify.

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Mpox: Making Vaccination Routine

support@deceraclinical.com (Carlos del Rio MD, Aniruddha (Anu) Hazra MD) — Fri, 14 Jun 2024 14:51:07 +0000

In this second podcast of our series, hear expert faculty explore the CDC recommendations for mpox protection and discuss how vaccination can lead to immunologic equity. Topics include:

Should we consider mpox an STI?
What strategies can be used to improve mpox vaccination and overcome the challenges of vaccine implementation?
Can mpox vaccine be coadministered with other vaccines?
What is the intersection between mpox and HIV?

Presenters

Carlos del Rio, MD
Distinguished Professor of Medicine (Infectious Diseases)
Emory University School of Medicine
Professor of Global Health and Epidemiology
Rollins School of Public Health
Atlanta, Georgia

Aniruddha (Anu) Hazra, MD
Assistant Professor of Medicine, Section of Infectious Disease and Global Health
Director, Infectious Diseases Fellowship Program
Medical Director, UCM Sexual
Wellness Clinic
University of Chicago
Chicago, Illinois

Learn more about the key aspects of mpox infections and prevention through vaccination in our full program,“Protection Beyond Outbreaks: Routine Mpox Vaccination for Vulnerable Populations.”

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google  Podcasts, or Spotify.

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Mpox Infection and Prevention

support@deceraclinical.com (Carlos del Rio MD, Aniruddha (Anu) Hazra MD) — Fri, 14 Jun 2024 14:25:06 +0000

Hear expert faculty answer common questions about the risk, impact, and recommendations for protection against mpox, including:

Why is mpox relevant to clinical practice?
Who is at highest risk for mpox?
How is mpox transmitted, and what are the clinical manifestations and complications of mpox infections?
What are current ACIP recommendations for mpox vaccination?
What about pre- and postexposure vaccination?

Presenters

Learn more about thekey aspects of mpox infections and prevention through vaccination in our full program,“Protection Beyond Outbreaks: Routine Mpox Vaccination for Vulnerable Populations.”

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Breaking Down Key PrEP Barriers: Patient and Regimen-Based Factors

support@deceraclinical.com (Roger Bedimo MD MS FACP) — Fri, 31 May 2024 16:35:10 +0000

In this episode, Roger Bedimo, MD, MS, FACP, examines patient and regimen-based PrEP barriers and discusses practical interventions to support PrEP adherence in key populations. Topics covered include:

Individual and community perspectives on PrEP barriers
Key barriers by principal populations
Strategies to support PrEP delivery
PrEP options for key populations
PrEP efficacy based on adherence in cisgender men and women
Comparing FTC/TDF vs FTC/TAF or CAB for PrEP
PrEP in pregnancy and breastfeeding
Drug–drug interactions with gender-affirming hormone therapy

Presenter:

Roger Bedimo, MD, MS, FACP
Professor of Medicine
Interim Director, Office of Global Health
UT Southwestern Medical Center
Chief, Infectious Diseases Section
VA North Texas Health Care System
Dallas, Texas

Content based on an online CME program supported by an independent educational grant from ViiV Healthcare.

Link to full program:
https://bit.ly/49x0W6D

Follow along with the slides:
https://bit.ly/3KmW4pN

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Actively Countering Health Disparities to Improve PrEP Uptake

support@deceraclinical.com (Roger Bedimo MD MS FACP) — Fri, 31 May 2024 16:11:20 +0000

In this episode, Roger Bedimo, MD, MS, FACP, discusses strategies to overcome health disparities to improve PrEP uptake, including:

Targeting key populations that would benefit from PrEP but have low rates of uptake, such as transgender women and people who inject drugs
Addressing intersectionality
Overcoming implicit bias
Addressing PrEP inequity by geographic region
Expanding PrEP uptake by expanding HCPs who prescribe it
Improving PrEP education for both patients and HCPs

Presenter:
Roger Bedimo, MD, MS, FACP
Professor of Medicine
Interim Director, Office of Global Health
UT Southwestern Medical Center
Chief, Infectious Diseases Section
VA North Texas Health Care System
Dallas, Texas

Content based on an online CME program supported by an independent educational grant from ViiV Healthcare.

Link to full program:
https://bit.ly/49x0W6D

Follow along with the slides:
https://bit.ly/3KmW4pN

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Addressing Provider and Structural PrEP Barriers

support@deceraclinical.com (Roger Bedimo MS MS FACP) — Fri, 31 May 2024 15:24:19 +0000

In this episode, Roger Bedimo, MD, MS, FACP, examines provider-based and structural PrEP barriers and discusses practical methods for healthcare professionals to overcome these challenges. Topics covered include:

Potential provider barriers to prescribing PrEP
Strategies to facilitate conversations about PrEP
Addressing the gap in PrEP provider training
Structural barriers for PrEP coverage, such as lack of insurance and complexity of billing
Informed consent for minors
CDC guidelines on HIV testing and renal or lipid monitoring while on PrEP
The role of PrEP champions or PrEP navigators, such as in the SNAPS PrEP Navigation Program
Solutions to common problems with PrEP persistence, such as use of telehealth and same-day PrEP initiation
Expanding PrEP options

Presenter:

Content based on an online CME program supported by an independent educational grant from ViiV Healthcare.

Link to full program:
https://bit.ly/49x0W6D

Follow along with the slides:
https://bit.ly/3KmW4pN

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Proactively Considering if Each Person Is on the Right HIV ART Regimen for Them

Thu, 16 May 2024 13:46:48 +0000

In this episode, Tristan J. Barber, MA, MD, FRCP, and Roger Bedimo, MD, MS, FACP, help you decide whether and how to modify ART in virologically suppressed individuals by critically appraising whether using newer agents may improve their treatment satisfaction.

Listen to their conversation about their own approaches to evaluating whether each person living with HIV is taking the best ART regimen for them, as well as ways to proactively assess challenges people may be facing with their HIV ART.

Presenters

Tristan J. Barber, MA, MD, FRCP
Consultant in HIV Medicine
Royal Free London NHS Foundation Trust
Honorary Associate Professor
Institute for Global Health
University College London
London, United Kingdom

Roger Bedimo, MD, MS, FACP
Professor of Medicine
Interim Director, Office of Global Health, UT Southwestern Medical Center
Chief, Infectious Diseases Section,
VA North Texas Health Care System
Dallas, Texas

Follow along with the slides here.
https://bit.ly/44N2w2Q

See the full program here.
https://bit.ly/450Ql2x

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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HIV Monitoring for People Receiving Long Acting PrEP

support@deceraclinical.com (Jonathan Appelbaum MD FACP AAHIVS) — Fri, 10 May 2024 20:24:35 +0000

In this episode, Jonathan Appelbaum, MD, FACP, AAHIVS, discusses the updated CDC guidance on how to monitor for HIV in people receiving PrEP, including:

Rationale for why HIV monitoring differs for people receiving LA vs daily PrEP
Description of LEVI syndrome
How to transition a person from LA PrEP to HIV ART if they test positive for HIV

Presenter:

Jonathan Appelbaum, MD, FACP, AAHIVS
Laurie L. Dozier, Jr., MD Education Director and Professor of Internal Medicine
Chair, Department of Clinical Sciences
Florida State University College of Medicine
Medical Director
Care Point Health and Wellness
Tallahassee, Florida

Link to the full program:
https://bit.ly/49x0W6D

Link to the slideset:
https://bit.ly/4bzZoth

To get access to all of our new podcast episodes, subscribe to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Studies of LA ART in People With Adherence Challenges or Viremia

support@deceraclinical.com (Jonathan Appelbaum MD FACP AAHIVS) — Fri, 10 May 2024 14:39:17 +0000

In this episode, Jonathan Appelbaum, MD, FACP, AAHIVS, discusses the newest data supporting LA ART use in people with adherence challenges or viremia, including:

The LATITUDE study, an open-label phase III study of LA CAB + RPV in people with a suboptimal response or nonadherence to oral ART
Updates to the Ward 86 cohort, which showed 81% of patients with viral suppression on LA CAB + RPV at Week 48
The CARES study, an open-label, noninferiority phase IIIb study of LA CAB + RPV in people with baseline resistance mutations

Presenter:

Link to the full program:
https://bit.ly/49x0W6D

Link to the slideset:
https://bit.ly/4bzZoth

To get access to all of our new podcast episodes, subscribe to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts or Spotify.

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Simplifying RSV Vaccination: Expert Q&A

Wed, 8 May 2024 14:00:52 +0000

In this episode, Angela Branche, MD, FIDSA, and Jewel Mullen, MD, MPH, MPA, FACP, address commonly asked questions about the RSV vaccine, including:

Considerations for vaccine eligibility
Recommendations for pregnant persons
Vaccine administration based on RSV seasonality
Use of the vaccine in persons receiving immunosuppressive medications
Safety data (eg, risk of serious adverse events)
Natural immunity of RSV
Vaccine cost and insurance coverage

Faculty:

Angela Branche, MD, FIDSA
Associate Professor of Medicine
Division of Infectious Diseases
Department of Medicine
University of Rochester
Rochester, New York

Jewel Mullen, MD, MPH, MPA, FACP
Associate Dean for Health Equity
Associate Professor of Population Health and Internal Medicine
University of Texas at Austin Dell Medical School
Austin, Texas

Content based on a CME program supported by an educational grant from GlaxoSmithKline.

Follow along with a downloadable slideset at:
https://bit.ly/44vCnFu

Link to full program:
https://bit.ly/3WvSY9Z

To get access to all of our new podcasts, subscribe to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Implementing RSV Vaccines Into Practice

support@deceraclinical.com (Jewel Mullen MD MPH MPA FACP) — Tue, 7 May 2024 18:45:16 +0000

In this episode, Jewel Mullen, MD, MPH, MPA, FACP, discusses strategies for implementing RSV vaccines into practice, with an emphasis on:

Understanding the reasoning for Advisory Committee on Immunization Practices RSV vaccine recommendations
Factors that influence vaccine uptake and patient decision-making
Considerations for patient and healthcare professional vaccine hesitancy
Building vaccine confidence in both patients and healthcare professionals
Using shared decision-making models (eg, SHARE approach)

Faculty:

Jewel Mullen, MD, MPH, MPA, FACP
Associate Dean for Health Equity
Associate Professor of Population Health and Internal Medicine
University of Texas at Austin Dell Medical School
Austin, Texas

Content based on a CME program supported by an educational grant from GlaxoSmithKline.

Follow along with a downloadable slideset at:
https://bit.ly/44vCnFu

Link to full program:
https://bit.ly/3WvSY9Z

To get access to all of our new podcasts, subscribe to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Understanding Risk Factors for Severe RSV Disease

support@deceraclinical.com (Angela Branche MD FIDSA) — Tue, 7 May 2024 04:00:00 +0000

In this episode, Angela Branche, MD, FIDSA, explores the burden of RSV disease in older adults, including:

RSV seasonality and disease burden
Symptoms and complications of RSV infection
Older age as a key risk factor for severe RSV disease and complications (eg, pneumonia, hospitalization)
Comorbidities associated with increased risk of RSV hospitalization
RSV hospitalization rates among different racial and ethnic minority groups and socioeconomic statuses

Faculty:
Angela Branche, MD, FIDSA
Associate Professor of Medicine
Division of Infectious Diseases
Department of Medicine
University of Rochester
Rochester, New York

Content based on a CME program supported by an educational grant from GlaxoSmithKline.

Follow along with a downloadable slideset at:
https://bit.ly/44vCnFu

Link to full program:
https://bit.ly/3WvSY9Z

To get access to all of our new podcasts, subscribe to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Optimizing Shingles Vaccine Uptake

Tue, 30 Apr 2024 15:11:38 +0000

Using common case scenarios, Robert H. Hopkins, Jr., MD, MACP, and Laura P. Hurley, MD, MPH, discuss strategies for optimizing shingles vaccine uptake, including:

The pathophysiology of shingles to better understand risk and burden
CDC guidelines and ACIP shingles vaccine recommendations, including considerations for those who are immunocompromised
Strategies for optimizing shingles vaccine uptake no matter the clinical setting
How to address shingles vaccine‒related adverse events
Addressing insurance-related concerns

Presenters:

Robert H. Hopkins, Jr., MD, MACP
Professor of Internal Medicine and Pediatrics
Chief, Division of General Internal Medicine
University of Arkansas for Medical Sciences
School of Medicine
Little Rock, Arkansas

Laura P. Hurley, MD, MPH
General Internist and Health Services Researcher
Associate Professor of Medicine
Department of General Internal Medicine
University of Colorado Anschutz Medical Campus
Aurora, Colorado

Link to downloadable slides:
https://bit.ly/4aWn6jh

Link to full program:
https://bit.ly/4aWBiJ0

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Integrating New Data From CROI 2024: Pharmacist Perspectives

Mon, 29 Apr 2024 13:07:46 +0000

In this episode, Samantha Strong, PharmD, BCACP, AAHIVP, CDCES, and Nimish Patel, PharmD, PhD, AAHIVP, cover the most impactful clinical studies presented at CROI 2024, including:

New data on long-acting ART, including:
- The CARES study of LA CAB + RPV in a sub-Saharan African population using a public health approach
- The IMPAACT 2017 MOCHA study evaluating switching to LA CAB + RPV in adolescents living with HIV
- The ACTG A5359 LATITUDE study of LA CAB + RPV in people with adherence challenges to oral ART
- Updated data from San Francisco’s Ward 86 Clinic using LA CAB + RPV in people without viral suppression at baseline
- Case series of LA CAB (± RPV) + LEN for select people living with HIV unable to take oral ART and unable to use LA CAB + RPV alone
Data on HIV and STI prevention, including:
- The impact of Doxy-PEP guideline implementation on STIs in men who have sex with men and transgender women in San Francisco
- BIC/FTC/TAF for PEP
- Offering PrEP following PEP

Presenters:

Samantha Strong, PharmD, BCACP, AAHIVP, CDCES
Clinical Director of Pharmacy
Nevada Health Centers
Las Vegas, Nevada

Nimish Patel, PharmD, PhD, AAHIVP
Professor of Clinical Pharmacy
Skaggs School of Pharmacy & Pharmaceutical Sciences
University of California, San Diego
La Jolla, California

To access all of our new podcast episodes, subscribe to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

See the full program here:
https://bit.ly/49x0W6D

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

How Primary Care Providers Can Expand Their Role in HBV Management

Fri, 26 Apr 2024 16:25:14 +0000

In this episode, learn how early and sustained HBV care can be enhanced by expanding the role of primary care providers in HBV management. Learn how to:

Engage key stakeholders in the provision of HBV care
Provide HBV management resources to support PCPs who are doing screening
Consider specialty and primary care collaborations that empower PCPs with clear guidance on how to manage patients living with HBV

Presenters:

Su Wang, MD, MPH, FACP
Medical Director
Center for Asian Health and Viral Hepatitis Programs
Cooperman Barnabas Medical Center
RWJBarnabas-Rutgers Medical Group
Associate Member
Health Care Policy and Aging Research
The Rutgers Institute for Health
Senior Advisor
Global Health, Hepatitis B Foundation
Florham Park, New Jersey

Richard R. Andrews, MD, MPH
President, Houston Viral Hepatitis Task Force
Former Co-Chair, National Task Force on Hepatitis B
Board-Certified Family Medicine
Addiction Medicine Physician
Houston, Texas

Ruth Brogden, MPH
Patient Advocate

Amy S. Tang, MD
Former Co-Chair, National Task Force on Hepatitis B
Director of Immigrant Health
North East Medical Services
San Francisco, California

Link to full program:
https://bit.ly/3TuqFHI

Link to the slides:
https://bit.ly/44hXpHu

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Beyond Viral Suppression: A Case Study Addressing Internalized HIV Stigma

support@deceraclinical.com (Gregory Huhn MD MPHTM) — Thu, 11 Apr 2024 15:10:10 +0000

In this episode, Gregory Huhn, MD, MPHTM, uses a case study to explore the reasons healthcare professionals and people living with HIV may want to further optimize ART in the setting of viral suppression.

To determine the best outcome for this case study, Dr Huhn discusses the reasons individuals may not be satisfied with daily oral ART and examines data to suggest that, for some individuals with virologic suppression, switching to long-acting ART may address internalized HIV stigma.

Finally, Dr Huhn takes a look at the optimal candidates for switching to a long-acting ART regimen and settings where proviral DNA genotyping may be considered prior to switching.

Presenter:

Gregory Huhn, MD, MPHTM
Interim Chief, Division of Infectious Diseases
Senior Director of HIV Services
Cook County HIV Integrated Programs
Interim Medical Director, The RMR CORE Center
Professor, Division of Infectious Diseases
Rush University Medical Center
Chicago, Illinois

To access all of our new podcast episodes, subscribe to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

See the full program here.

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Linkage to Care After HBV Diagnosis: Sharing Session 3

support@deceraclinical.com (Maria Buti MD) — Wed, 10 Apr 2024 15:20:00 +0000

In this episode, Maria Buti, MD, and her patient discuss opportunities to optimize care for people living with hepatitis B virus (HBV), including:

Barriers to HBV screening, including patient- and provider-specific barriers (eg, lack of education, failure to disclose or discuss risk factors, perceived low risk, stigma)
Applying CDC recommendations for universal HBV screening in adults
Strategies to improve HBV transitions of care (eg, improved education, simplify criteria for screening and monitoring, alternative testing sites)
Importance of testing close contacts for HBV after initial diagnosis and promoting HBV vaccination

Presenter:

Maria Buti, MD
Professor of Medicine
Senior Consultant
Liver Unit
Hospital Universitario Valle Hebron
Barcelona, Spain

Content based on an online CME program supported by an independent educational grant from Gilead Sciences, Inc.

Link to full program:
https://bit.ly/49TuZ8U

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Key HIV Studies From CROI 2024 Influencing Clinical Practice

support@deceraclinical.com (Joseph J. Eron Jr. MD, Monica Gandhi MD MPH) — Fri, 29 Mar 2024 15:09:10 +0000

In this episode, Joseph J. Eron, Jr., MD, and Monica Gandhi, MD, MPH, discuss the key HIV studies from CROI 2024 that are influencing their clinical practice, including:

New data surrounding long-acting ART, including:
- The CARES study of LA CAB + RPV in a Sub-Saharan African population using a public health approach
- The IMPAACT 2017 MOCHA study evaluating switching to LA CAB + RPV in adolescents living with HIV
- The ACTG A5359 LATITUDE study of LA CAB + RPV in people with adherence challenges to oral ART
- Updated data from San Francisco’s Ward 86 Clinic using LA CAB + RPV in people without viral suppression at baseline
- Case series of LA CAB (± RPV) + LEN for select people living with HIV unable to take oral ART and unable to use LA CAB + RPV alone
Data on comorbidities and coinfections, including:
- A REPRIEVE proteomic analysis to elucidate mechanistic pathways of statin effects on plaque
- The ACTG A5371 SLIM LIVER study of semaglutide for MASLD in people living with HIV
- The impact of Doxy-PEP guideline implementation on STIs in men who have sex with men and transgender women in San Francisco
Potential novel treatment options on the horizon for people living with HIV, including:
- Phase II data on LEN + ISL dosed orally once weekly
- Early data on other oral weekly options
- Data on bNAbs in combination or with other ART agents

Presenters:

Joseph J. Eron, Jr., MD
Professor of Medicine, School of Medicine
Herman and Louise Smith Distinguished Professor
Chief, Division of Infectious Diseases
Director, Clinical Core, UNC Center for AIDS Research
Adjunct Professor of Epidemiology
Gillings School of Global Public Health
University of North Carolina at Chapel Hill
Chapel Hill, North Carolina

Monica Gandhi, MD, MPH
Professor of Medicine
Division of HIV, Infectious Diseases, and Global Medicine
Medical Director, Ward 86 HIV Clinic
University of California, San Francisco
San Francisco, California

Content based on an online CME program supported by independent educational grants from Gilead Sciences; Merck & Co., Inc.; and ViiV Healthcare.

Link to full program:
https://bit.ly/4awdWJM

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts or Spotify.

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How to Implement Earlier Hepatitis B Treatment

Tue, 26 Mar 2024 18:30:18 +0000

In this episode, Mark S. Sulkowski, MD, FIDSA, FAASLD; Tatyana Kushner, MD, MSCE; Paul Y. Kwo, MD; and patient advocate Jacki Chen, PhD, consider barriers and solutions for more expansive HBV treatment in the United States. Topics include:

Patient subgroups to consider for treatment outside guideline criteria
Adverse event and cost-effectiveness considerations
Integration of patient perspectives in wider treatment

Presenters:

Mark S. Sulkowski, MD, FIDSA, FAASLD
Professor of Medicine
Director, Division of Infectious Diseases, Johns Hopkins Bayview Medical Center
Johns Hopkins University School of Medicine
Baltimore, Maryland

Tatyana Kushner, MD, MSCE
Associate Professor
Division of Liver Diseases
Icahn School of Medicine at Mount Sinai
New York, New York

Paul Y. Kwo, MD
Professor of Medicine
Director of Hepatology
Stanford University School of Medicine
Palo Alto, California

Jacki Chen, PhD
Patient Advocate

Link to full program:
https://bit.ly/3TuqFHI

Link to the slides:
https://bit.ly/4a60GM4

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Empowering Patients With Education on HBV: Sharing Session 2

support@deceraclinical.com (Robert Wong MD MS, Evelyn (patient)) — Mon, 11 Mar 2024 19:03:46 +0000

In this episode, Robert Wong, MD, MS, and a patient discuss opportunities to optimize care for people living with hepatitis B virus (HBV), including:

Opportunities to improve patient education, including education for expectant mothers with HBV
Potential cultural considerations that may result in delayed HBV diagnosis and care
Stigma reduction with universal HBV screening and vaccination
Strategies to improve patient education (eg, online resources, advocacy groups, use of layman’s terms and diagrams, repetition)

Presenter:

Robert Wong, MD, MS
Clinical Associate Professor
Division of Gastroenterology and Hepatology
Stanford University School of Medicine
Palo Alto, California

Content based on an online CME program supported by an independent educational grant from Gilead Sciences, Inc.

Link to full program:
https://bit.ly/49TuZ8U

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Switching HIV ART in Older People With Weight Gain and Cardiovascular Comorbidities

support@deceraclinical.com (Roger Bedimo MD MS FACP) — Fri, 8 Mar 2024 14:35:25 +0000

Listen to Roger Bedimo, MD, MS, FACP, discuss considerations for older people living with HIV, including:

Polypharmacy and deprescribing
The risk of cardiovascular events with various ART regimens
Approaches for managing weight gain

Presenter:

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

To download the slides:
https://bit.ly/49zrnZs

To view the full online program:
https://bit.ly/49x0W6D

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Optimizing ART in Priority Populations: Initiating ART in Transgender Women

support@deceraclinical.com (Roger Bedimo MD MS FACP) — Mon, 4 Mar 2024 15:06:46 +0000

In this episode, Dr. Bedimo discusses best practices for individualized care in transgender women living with HIV, including:

Providing services in a gender-affirmative care model
Proactive counseling on drug-drug interactions with gender-affirming hormone therapy
Strategies to reduce adverse events

Presenter:

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

To download the slides:
https://bit.ly/49zrnZs

To view the full online program:
https://bit.ly/49x0W6D

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COVID-19 Case Challenges: Employing Outpatient Antivirals and Addressing Drug‒Drug Interactions

support@deceraclinical.com (Renslow Sherer MD, Trinh P. Vu PharmD BCIDP) — Tue, 27 Feb 2024 22:11:35 +0000

In this episode, Renslow Sherer, MD, and Trinh P. Vu, PharmD, BCIDP, discuss how to optimize the use of COVID-19 antivirals and how to navigate drug-drug interactions between COVID-19 treatments and a patient’s home medications. Their discussion includes:

Current COVID-19 landscape
COVID-19 testing and vaccination recommendations
Treatment guidelines and antiviral options for nonhospitalized adults with COVID-19
Resources for assessing and managing COVID-19 antiviral-related drug-drug interactions
Answers to learners’ most pressing questions

Presenters:

Renslow Sherer, MD
Professor of Medicine
Section of Infectious Diseases and Global Health
University of Chicago
Chicago, Illinois

Trinh P. Vu, PharmD, BCIDP
Clinical Pharmacy Specialist in Infectious Diseases
Department of Pharmacy
Emory University Hospital Midtown
Atlanta, Georgia

Slideset: https://bit.ly/4c6kwbJ

Downloadable resource:
https://bit.ly/49rofP6

Full program:
https://bit.ly/3P16TR8

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts or Spotify.

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New Audio Updates: CCO Independent Conference Coverage of Hepatitis B at AASLD 2023

support@deceraclinical.com (Nancy Reau MD) — Mon, 5 Feb 2024 14:59:15 +0000

In this episode, Nancy Reau, MD, discusses new data on hepatitis B virus presented at AASLD 2023, including:

Current therapies
- Studies 108 and 110: Factors Linked With Lack of Virologic Suppression After 8 Yr of TAF or TDF
- Kaiser Permanente Northern California: HCC or Death With TDF vs ETV for Chronic Hepatitis B
- Early vs Late Postpartum Cessation of TDF Initiated for Prevention of Vertical HBV Transmission
Investigational functional cure strategies
- B-Together: Sequential Bepirovirsen and PegIFN Added to NA Therapy for Chronic HBV Infection
- MARCH Part B: VIR-3434 ± VIR-2218 ± PegIFN Added to NA Therapy for Chronic HBV Infection
- REEF-IT: JNJ-3989 + NA ± JNJ-6379 With PegIFN Add-on Consolidation in Patients With HBeAg-Positive CHB
- HBV003: VTP-300 + Nivolumab Added to NA Therapy for Chronic HBV Infection
- CVP-NASVAC: Nasally Administered Therapeutic Vaccine for Chronic HBV Infection

Presenter:
Nancy Reau, MD
Professor of Medicine
Richard B. Capps Chair of Hepatology
Chief, Section of Hepatology
Associate Director, Solid Organ Transplantation
Rush University Medical Center
Chicago, Illinois

Link to full program:
https://bit.ly/47XJlU4

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Reconsidering Your Approach: Strategies to Support PrEP Persistence and Reengagement

support@deceraclinical.com (LaRon E. Nelson PhD RN FNP FNAP FNYAM FAAN) — Wed, 31 Jan 2024 13:42:53 +0000

In this episode, LaRon E. Nelson, PhD, RN, FNP, FNAP, FNYAM, FAAN, discusses the role that healthcare professionals (HCPs) may be playing in their patients’ pre-exposure prophylaxis (PrEP) persistence and strategies to modify their approach to encourage persistence, from Clinical Care Options (CCO), including:

Racial disparities in the PrEP care continuum
Consideration that PrEP persistence may be less about relationship to the drug than the environment
Examples of HCP implicit bias regarding PrEP responsibility based on racism and sexual prejudice
Impact of HCP implicit bias on PrEP persistence
Impact of racism on clinical cognition
The demonstrated effects of stereotype threat and the potential healthcare implications
Ways to improve clinical conversations about PrEP
Providing person-centered care to encourage PrEP persistence using the Client‑Centered Care Coordination (C4™) Model

Faculty

LaRon E. Nelson, PhD, RN, FNP, FNAP, FNYAM, FAAN
Independence Foundation Professor
School of Nursing
Yale University
New Haven, Connecticut

Follow along with the slides:
https://bit.ly/497cahK

Link to full program:
https://bit.ly/3ZlICsL

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease podcast on Apple Podcasts, Google Podcasts, or Spotify.

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My Journey With HBV and HDV: Sharing Session 1

support@deceraclinical.com (Nancy Reau MD) — Wed, 24 Jan 2024 16:02:24 +0000

In this episode, Nancy Reau, MD, and her patient discuss opportunities to optimize care for people living with hepatitis B virus and hepatitis delta virus, including:

The importance of patient education along the care continuum
Ensuring smooth transitions of care and communication between medical teams
Screening hepatitis delta in persons with chronic hepatitis B
Managing hepatitis delta, including considerations for clinical trials
Promoting patient advocacy

Presenter:

Nancy Reau, MD
Professor of Medicine
Chief, Section of Hepatology
Associate Director, Solid Organ Transplantation
Richard B. Capps Chair of Hepatology
Rush University Medical Center
Chicago, Illinois

Content based on an online CME program supported by an independent educational grant from Gilead Sciences, Inc.

Link to full program: bit.ly/3SrMuGO

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

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Why I Started and Why I Stayed on HIV PrEP

support@deceraclinical.com (David Saunders) — Fri, 12 Jan 2024 14:30:00 +0000

In this episode, David Saunders discusses the value of nonstigmatizing discussions between people using HIV pre-exposure prophylaxis (PrEP) and healthcare professionals, including:

Encouraging accountability to individualize adherence strategies and improve persistence to PrEP
Reducing stigma, discrimination, and prejudice in healthcare settings to foster PrEP persistence

Faculty:

David Saunders
PrEP User and Advocate

Link to full program:
https://bit.ly/3ZlICsL

To automatically get new episodes as soon as they launch, subscribe to the CCO Infectious Disease podcast.

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Long-Acting PrEP: Strategies to Support PrEP Persistence and Reengagement

support@deceraclinical.com (Sarah M. Wood MD MS) — Wed, 10 Jan 2024 19:21:25 +0000

In this episode, Sarah M. Wood, MD, MS, discusses data and recommendations for long-acting pre-exposure prophylaxis (PrEP) as a strategy to support PrEP persistence and engagement for adolescents, including:

The PrEP care continuum for adolescents
System barriers to PrEP coverage and privacy concerns for adolescents
The benefits and challenges of same-day PrEP initiation and real-world data to support it
Interventions to support PrEP persistence
PrEP options for different populations and the data to support the efficacy of long-acting cabotegravir (CAB) PrEP from HPTN 083 and HPTN 084
Data and recommendations for a CAB PrEP oral lead-in
Data from HPTN 083 showing no interaction between feminizing hormone therapy and long-acting CAB PrEP
Project LifeSkills: a culturally specific, empowerment-based, group-delivered behavioral HIV prevention intervention for young transgender women

Faculty

Sarah M. Wood, MD, MS
Assistant Professor of Pediatrics
Division of Adolescent Medicine
Perelman School of Medicine
University of Pennsylvania
Children’s Hospital of Philadelphia
Philadelphia, Pennsylvania

Follow along with the slides:
https://bit.ly/3Ha9Kmt

Link to full program:
https://bit.ly/3ZlICsL

To automatically get new episodes as soon as they launch, subscribe to the CCO Infectious Disease podcast show.

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RSV Vaccines in Adults: A Risk-Based Approach

support@deceraclinical.com (Angela Branche MD) — Wed, 27 Dec 2023 19:17:51 +0000

In this episode, Angela Branche, MD, discusses RSV vaccines in older adults, including:

Current Advisory Committee on Immunization Practices recommendations
Risk factors associated with severe RSV disease, including RSV-related hospitalizations
Approach to stratifying risk factors (eg, age, comorbidities) in determining which adults may benefit from the RSV vaccine
Ongoing research on RSV vaccines in younger adults (eg, aged 40s and 50s years) with chronic comorbidities
Health disparities related to RSV vaccines
Considerations for a risk-based approach, rather than age alone, to determine vaccine candidacy

Faculty:

Angela Branche, MD
Associate Professor of Medicine
Division of Infectious Diseases
Department of Medicine
University of Rochester
Rochester, New York

Link to full program:
https://bit.ly/3nb25xe

Link to downloadable slides:
https://bit.ly/3TsXym5

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How to Implement Earlier Hepatitis B and Hepatitis Delta Screening

support@deceraclinical.com (Decera Clinical Education) — Fri, 22 Dec 2023 05:00:00 +0000

In this episode, Douglas Dieterich, MD, leads a panel discussion with Camilla S. Graham, MD, MPH, and Robert Wong, MD, MS, to consider advantages and barriers to universal screening for chronic HBV infection and universal HDV screening in adults with HBV in the United States. Topics include:

Updated CDC recommendations for one-time universal screening for HBV
Addressing patient-, provider-, and system-level barriers to universal HBV screening
Best practices for implementation of HDV screening

Presenters:

Douglas Dieterich, MD
Director, Institute for Liver Medicine

Professor of Medicine

Division of Liver Diseases

Mount Sinai School of Medicine

New York, New York

Camilla S. Graham, MD, MPH
Co-Director, Viral Hepatitis Clinic
Division of Infectious Diseases
Beth Israel Deaconess Medical Center
Harvard Medical School
Boston, Massachusetts

Robert Wong, MD, MS
Clinical Associate Professor
Division of Gastroenterology and Hepatology
Stanford University School of Medicine
Palo Alto, California

Link to full program:
https://bit.ly/3TuqFHI

Link to the slides:
https://bit.ly/4atS42z

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Q&A on HIV PrEP: Episode 7 for Advanced Practice Providers

Thu, 21 Dec 2023 20:35:35 +0000

In this episode, Tavell L. Kindall, PhD, DNP, ARNP, FNP-BC, AACRN, AAHIVS, FAANP, and Anne Teitelman, PhD, FNP-BC, FANNP, FAAN, discuss key PrEP considerations for advanced practice providers in primary care settings, including:

The importance of having PrEP navigators to help with logistics and be a point of contact for patients
Where to find education and resources to familiarize yourself with PrEP and its prescribing
Safety considerations and adverse events associated with PrEP options
PrEP coverage and cost
How to discontinue PrEP and the risk of resistance if someone acquires HIV while taking PrEP

Faculty

Tavell L. Kindall, PhD, DNP, ARNP, FNP-BC, AACRN, AAHIVS, FAANP
Director, HIV Prevention and Treatment
St. Thomas Community Health Center
New Orleans, Louisiana

Anne Teitelman, PhD, FNP-BC, FANNP, FAAN
Associate Professor Emeritus of Nursing and Global Women’s Health
Department of Family and Community Health
School of Nursing
University of Pennsylvania
Professor
Thomas Jefferson University
College of Nursing
Philadelphia, Pennsylvania

Link to full program:
https://bit.ly/3PZGYdR

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Mental Health Challenges: Dialogues on Optimizing Engagement in HIV Care

support@deceraclinical.com (Mark Brennan-Ing PhD, Nina I. Martinez) — Wed, 20 Dec 2023 05:00:00 +0000

In this podcast episode, Mark Brennan-Ing, PhD, and Nina I. Martinez discuss mental health challenges in people living with HIV and much-needed strategies to overcome these challenges to optimize engagement in HIV care, including:

The increased rates of mental health disorders and substance use among people living with HIV
How mental health disorders contribute to challenges with adherence to HIV treatment and engagement in care
How social isolation and stigma can affect outcomes despite access to HIV care and ART
The importance of mental health screenings as part of HIV care
Integrating mental health services into HIV care as a strategy to overcome mental health challenges being a barrier to care

Presenter:

Mark Brennan-Ing, PhD
Director of Research and Evaluation
Brookdale Center for Healthy Aging
Hunter College
The City University of New York
New York, New York

Nina I. Martinez
Public Health Consultant

Link to full program:
https://bit.ly/3TqVnl1

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Starting ART: Dialogues on Optimizing Engagement in HIV Care

support@deceraclinical.com (Isolde F. Butler MD MPH, Marissa Gonzalez) — Mon, 18 Dec 2023 19:37:29 +0000

In this podcast episode, Isolde Butler, MD, MPH, a healthcare professional caring for people living with HIV, and Marissa Gonzalez, an individual living with HIV, discuss strategies to improve healthcare professionals’ competencies in delivering optimal HIV care from the start to better support patients in overcoming barriers to sustained care engagement.

The topics they discuss include:

An introduction to the guidelines on ART initiation—start quickly and choose the therapy that is effective and tolerable
The patient experience, from initial diagnosis to treatment selection, noting that where people get diagnosed matters in determining the level of support they will receive
The complete HIV care team: healthcare professionals, navigators, case managers, behavioral health providers, mental health providers, and so on. Smaller clinics may not be able to provide adequate support to meet all patient needs
How to navigate the first visit after an HIV diagnosis, including patient–provider treatment discussions on the available therapies that can help with stigma
HIV stigma education; navigating the miseducation and misinformation

Presenters:

Isolde F. Butler, MD, MPH
Chief Medical Officer
Cresentcare
New Orleans, Louisiana

Marissa Gonzalez
Chair
Community Advisory Board
The Well Project

Link to full program:
https://bit.ly/3TqVnl1

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Engagement in Care: Dialogues on Optimizing Engagement in HIV Care

support@deceraclinical.com (Babfemi Taiwo MBBS, Vincent Chrisostomo) — Mon, 18 Dec 2023 18:09:45 +0000

In this podcast episode, Babafemi Taiwo, MBBS, and Vincent Crisostomo discuss the evolving treatment landscape for aging people living with HIV, encompassing the clinical and external resources necessary to support physical and psychosocial health. The topics discussed include:

• Mindful prescribing and understanding the impact an HIV diagnosis can have on one’s mental health, including social isolation

• How to address patients’ needs and establish a trusting relationship within the confines of a 15-minute clinic visit

• How research is helping healthcare professionals better understand this clinical situation and discover opportunities to equalize metrics

• The critical role of social workers and community organizations in patients’ overall care

• Accessing federal HIV disability resources

• Informed patient–provider discussion and counseling on medical decision-making regarding ART

• How healthcare professionals can move toward clinical practice that leaves no one behind

Presenter:

Babafemi Taiwo, MBBS
Gene Stollerman Professor of Medicine
Chief
Division of Infectious Diseases
Northwestern University Feinberg School of Medicine
Chicago, Illinois

Vincent Crisostomo
Director
Aging Services
San Francisco AIDS Foundation
San Francisco, California

Link to full program:
https://bit.ly/3TqVnl1

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Providing Options for PrEP Reengagement: Strategies to Support PrEP Persistence and Reengagement

support@deceraclinical.com (Kevin Astle PharmD BCPS BCACP AAHIVP CDCES) — Fri, 15 Dec 2023 05:00:00 +0000

In this episode, Kevin Astle, PharmD, BCPS, BCACP, AAHIVP, CDCES, discusses data and recommendations for providing HIV prevention options as a strategy to support PrEP persistence and engagement, including:

Postexposure prophylaxis (PEP) recommendations and the data for PEP-in-Pocket
Offering PrEP to everyone who receives PEP
Currently recommended PrEP options and the safety and adverse event considerations with each option
Monitoring recommendations for the different PrEP options
The importance of proactively addressing PrEP safety concerns that could lead to PrEP discontinuation

Faculty

Kevin Astle, PharmD, BCPS, BCACP, AAHIVP, CDCES
Assistant Professor
Pharmacotherapeutics and Clinical Research
University of South Florida Taneja College of Medicine
Tampa, Florida

Follow along with the slides:
bit.ly/48cULUN

Link to full program:
bit.ly/3ZlICsL

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Selected FXR Agonist PBC Studies: Conference Coverage of AASLD

support@deceraclinical.com (Kris V. Kowdley MD FAASLD FACP FACG) — Wed, 13 Dec 2023 17:52:11 +0000

During the 2023 American Association for the Study of Liver Diseases conference, exciting and important results from many primary biliary cholangitis (PBC) clinical trials were reported, including 3 late-breaking studies on the PPAR-δ agonist seladelpar, the dual PPAR agonist elafibranor, and the combination of the FXR agonist obeticholic acid and a fibrate.

In this episode, Kris V. Kowdley MD, FAASLD, FACP, FACG, discusses topline results from several of these studies and more, including:

A combination of 3 studies—HEROES, COBALT, and COBALT EC—that evaluated the real-world effectiveness and safety of second-line therapy in PBC where OCA was added to the treatment regimen of people with PBC with an incomplete response to ursodeoxycholic acid
Lessons learned from a long-term outcomes study of people with PBC
Results from 2 phase II studies of obeticholic acid plus bezafibrate in people with PBC who did not respond to or were intolerant of ursodeoxycholic acid

Presenter:

Kris V. Kowdley MD, FAASLD, FACP, FACG
Professor, Elson S. Floyd College of Medicine
Washington State University
Director, Liver Institute Northwest
Seattle, Washington

Link to reviews of other PBC studies from AASLD 2023:
https://bit.ly/3RvXXEI

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PrEP Talks: Strategies for Advanced Practice Providers to Increase Uptake

Tue, 12 Dec 2023 16:52:11 +0000

In this episode, Dr Tavell Kindall and Jona Tanguay discuss actionable strategies for advanced practice providers to increase the frequency at which PrEP is offered and initiated in primary care settings. Topics covered include:

Available training resources on how to offer PrEP in primary care
Affordable, accessible PrEP options, including patient assistance programs
Using electronic health records to identify candidates for PrEP
Opportunities to offer PrEP during appointments regarding birth control, STIs, or any other sexual health concerns
How to offer 3-site STI testing at your facility
Wrapping PrEP into primary care
Incorporating navigators or care coordinators to reduce logistical barriers and reach underserved populations
Rapid testing, mobile testing, and Tele-PrEP as ways to facilitate PrEP initiation and simplify routine PrEP visits
Healthcare professionals’ personal biases as a potential barrier to PrEP
Using ICD-10 codes for HIV PrEP as a way to further destigmatize PrEP and simplify billing

Faculty:

Tavell L. Kindall, PhD, DNP, ARNP, FNP-BC, AACRN, AAHIVS, FAANP
Director, HIV Prevention and Treatment
St. Thomas Community Health Center
New Orleans, Louisiana

Jona Tanguay, MMSc, PA-C, AAHIVS
Medical Program Lead - Substance Use Disorders at Whitman-Walker Health
Associate Medical Director - Transgender Health at Amida Care
President-Elect at GLMA: Health Professionals Advancing LGBTQ+ Equality
Clinical Instructor at Yale School of Medicine
Founder at ChemsexHarmReduction.org
Washington, DC

Content is supported by independent educational grants from Gilead Sciences, Inc. and ViiV Healthcare.

Link to full program:
https://bit.ly/3PZGYdR

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Where We Want to Be: The Search for a Cure for HIV

Mon, 11 Dec 2023 16:00:34 +0000

In this third of 3 episodes, global HIV experts and advocates discuss the current status of HIV cure research, including key concepts to understand and communicate when counselling patients, colleagues, and the broader community on HIV cure:

Latest understanding of the viral reservoir
New insights and questions on the best timing for cure interventions
Current investigational strategies showing promise
Ethical considerations related to participant education, representation in clinical trials, and planning for broad global access

Faculty:

Katharine J. Bar, MD
Associate Professor of Medicine
Director, Penn CFAR Virus and Reservoirs Core
University of Pennsylvania
Philadelphia, Pennsylvania

Jennifer Blanchette, PhD
Independent Contractor
Clinical Care Options
Colorado, United States

Krista L. Dong, MD
Clinical Director, FRESH Cohort
Assistant Professor of Medicine
Massachusetts General Hospital
Harvard Medical School
Boston, Massachusetts

Karine Dubé, DrPH, MPhil
Associate Professor
UCSD School of Medicine
Division of Infectious Diseases and Global Public Health
San Diego, California

Richard Jefferys
Basic Science, Vaccines & Cure Project Director
Treatment Action Group
New York, New York

Sharon R. Lewin, AO, FRACP, PhD, FAA, FAHMS
Director
Doherty Institute
Melbourne Laureate Professor and Head
Department of Infectious Diseases
The University of Melbourne
Consultant Physician
Victorian Infectious Diseases Service
Royal Melbourne Hospital
Consultant Physician and Adjunct Professor Department of Infectious Diseases
Alfred Hospital and Monash University
Melbourne, Australia

Angelina Namiba
Founder Member
4M Network of Mentor Mothers
London, United Kingdom

Link to full program:
https://bit.ly/3QFwv7n

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CRE-ating Success: How I Use Rapid Diagnostic Tests to Manage Carbapenem-Resistant Enterobacterales Bacteremia

support@deceraclinical.com (Julie Ann Justo PharmD MS FIDSA BCPS) — Thu, 7 Dec 2023 17:57:07 +0000

In this podcast, Julie Ann Justo, PharmD, MS, FIDSA, BCPS, discusses treatment of carbapenem-resistant Enterobacterales (CRE) infections, including:

Burden of CRE infections in the United States
Mechanisms of resistance
Changing epidemiology
Use of rapid diagnostic tests
IDSA guidance recommendations, including supporting data
Approach to designing treatment regimens, including weighing patient- and infection-related factors

Faculty:

Julie Ann Justo, PharmD, MS, FIDSA, BCPS
Clinical Pharmacist Lead – Infectious Diseases
Inpatient Pharmacy
Dartmouth Hitchcock Medical Center
Lebanon, New Hampshire

Link to full program:
https://bit.ly/41a8Mj0

Link to accompanying ClinicalThought commentary:
https://bit.ly/4865T57

Link to downloadable infographic:
https://bit.ly/3t7NpT2

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Investigational PPAR-delta Agonist for PBC Treatment and Race-Based Considerations for PBC Diagnosis: Conference Coverage of AASLD

support@deceraclinical.com (Stuart C. Gordon MD FAASLD) — Thu, 7 Dec 2023 05:00:00 +0000

During the 2023 American Association of the Study of Liver Diseases (AASLD) conference, exciting and important results from many primary biliary cholangitis (PBC) clinical trials were reported, including 3 late-breaking studies on the PPAR-delta agonist seladelpar, the dual PPAR agonist elafibranor, and the combination of the FXR agonist obeticholic acid and a fibrate.

In this episode, Stuart C. Gordon, MD, FAASLD, discusses topline results from one of these late-breaking studies and more, including:

A phase III study of an investigational PPAR-delta agonist (seladelpar) in people with PBC who had failed to respond to ursodeoxycholic acid
A study that explored racial differences as they relate to the presentation and diagnosis of PBC

Presenter:
Stuart C. Gordon, MD, FAASLD
Director of Hepatology
Henry Ford Health System
Professor of Medicine
Wayne State University School of Medicine
Detroit, Michigan

Link to commentary:
https://bit.ly/3GzRMt2

Link to reviews of other PBC studies from AASLD 2023:
https://bit.ly/3RvXXEI

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PrEP Talks: Uptake in Young Adults and Adolescents

support@deceraclinical.com (Errol L. Fields MD PhD MPH, Armonté Butler MPH) — Thu, 7 Dec 2023 05:00:00 +0000

In this episode, Errol L. Fields, MD, PhD, MPH, and Armonté Butler, MPH, a pre-exposure prophylaxis (PrEP) advocate, discuss strategies for overcoming barriers to uptake of PrEP for HIV in adolescents and young adults, based on the unique needs of this patient population. Topics covered include:

Methods for building trust between patients and providers
Ways to practice shared decision-making and how this process hinges on respecting patients’ autonomy and personhood
How to empower young people to ask for the assistance they need
How to navigate consent and confidentiality issues
Information about payment options
Strategies to improve adherence for youth
The best ways to provide support and flexibility throughout this process to promote persistence on PrEP

Faculty:

Errol L. Fields, MD, PhD, MPH
Associate Professor of Pediatrics
Division of Adolescent/Young Adult Medicine
Department of Pediatrics
Johns Hopkins School of Medicine
Baltimore, Maryland

Armonté Butler, MPH
Associate Director, LGBTQ Health & Rights
Advocates for Youth
Washington, DC

Content is supported by independent educational grants from Gilead Sciences, Inc. and ViiV Healthcare.

Link to full program:
https://bit.ly/3PZGYdR

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Investigational Dual PPAR Agonist, FXR Agonist With Fibrate, and Hyperlipidemia in People With PBC: Conference Coverage of AASLD

support@deceraclinical.com (Marlyn J Mayo MD) — Wed, 6 Dec 2023 19:12:39 +0000

In this episode, Marlyn J. Mayo, MD, discusses topline results from several of these studies and more, including:

A phase III study of an investigational dual PPAR α/δ agonist (elafibranor) in people with PBC who did not respond to or were intolerant of ursodeoxycholic acid (UDCA)
A study that evaluated the effectiveness and safety of second-line therapy in PBC where obeticholic acid with or without a fibrate was added to the treatment regimen of people with PBC with an incomplete response to UDCA
A retrospective review of the rates of hyperlipidemia, atherosclerosis, and/or hepatic steatosis in patients with PBC

Presenter:

Marlyn J. Mayo, MD
Professor of Internal Medicine
Division of Digestive & Liver Diseases
UT Southwestern Medical Center
Dallas, Texas

Link to commentary:
https://bit.ly/47PmGdc

Link to reviews of other PBC studies from AASLD 2023:
https://bit.ly/3RvXXEI

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Are We Making Our Patients Fight for PrEP?

support@deceraclinical.com (Martin Rios) — Mon, 4 Dec 2023 21:34:59 +0000

In this episode, Martin Rios discusses how pre-exposure prophylaxis (PrEP) persistence depends on healthcare professional knowledge, including:

Their own experiences with the various PrEP providers they have seen
The relief that has come with seeing PrEP providers who are supportive and knowledgeable about the different PrEP options
The challenges that have come with seeing PrEP providers who are unwilling to prescribe PrEP altogether or who will prescribe PrEP when asked but are not knowledgeable about the options

Faculty:

Martin Rios
PrEP User and Advocate
Philadelphia, Pennsylvania

Link to full program:
https://bit.ly/3ZlICsL

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Q&A on HIV PrEP: Episode 6 on Cisgender Women

support@deceraclinical.com (Meredith Clement MD, Whitney C. Irie MSW PhD) — Mon, 4 Dec 2023 20:59:26 +0000

In this episode, Meredith Clement, MD, and Whitney C. Irie, MSW, PhD, discuss key considerations for pre-exposure prophylaxis (PrEP) uptake in cisgender women, including:

How to incorporate conversations on PrEP during a short clinic visit
Helpful resources about PrEP to share with patients
Leveraging clinic staff to improve PrEP uptake and persistence
Available data on on-demand PrEP
Approach to discussing PrEP contraindications and adverse events with patients
Considerations for PrEP in pregnant persons or those wanting to conceive
The importance of inclusiveness in PrEP marketing
Key barriers limiting PrEP uptake in cisgender women (eg, stigma, risk perception)
Interventions to improve PrEP uptake

Faculty

Meredith Clement, MD
Associate Professor
Infectious Diseases
Louisiana State University
Health Sciences Center
New Orleans, Louisiana

Whitney C. Irie, MSW, PhD
Assistant Professor
Department of Social Work
Boston College
Brighton, Massachusetts

Link to full program:
https://bit.ly/3PZGYdR

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The Rise of RSV: Updates on Seasonality

support@deceraclinical.com (Helen Y Chu MD MPH) — Thu, 30 Nov 2023 19:28:09 +0000

In this episode, Helen Y. Chu, MD, MPH, shares updates on RSV seasonality, including:

Surveillance limitations due to the testing availability in adults
Current 2023/2024 season trends, including predictions for other respiratory viruses (eg, influenza, SARS-CoV-2)
Considerations for RSV administration
RSV vaccine coadministration with influenza and COVID-19 vaccines

Faculty:

Helen Y. Chu, MD, MPH
Associate Professor of Medicine
Division of Allergy & Infectious Diseases
University of Washington
School of Medicine
Seattle, Washington

Link to full program: https://bit.ly/3nb25xe

Link to downloadable slides: https://bit.ly/3TsXym5

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Ready, Set, Vaccinate! RSV Vaccination for Older Adults

support@deceraclinical.com (Richard Zimmerman MD MPH FAAFP) — Thu, 30 Nov 2023 19:22:44 +0000

In this episode, Rick Zimmerman, MD, MPH, FAAFP, discusses RSV vaccines in older adults, including:

Breakthroughs in RSV vaccine development
RSV vaccine snapshot in older adults
FDA-approved RSV vaccines for older adults
CDC evidence to recommendations framework for vaccines
RSV burden in older populations
Benefits and harms of RSV vaccination
RSV vaccine efficacy and safety in older adults
CDC Advisory Committee Immunization Practices recommendations for RSV vaccines in older adults
Populations at high risk for severe RSV disease
Vaccination considerations based on the upcoming RSV season

Faculty:

Richard Zimmerman, MD, MPH, FAAFP
Professor
Department of Family Medicine and Clinical Epidemiology
University of Pittsburgh
Pittsburgh, Pennsylvania

Content based on an online CME program supported by an independent educational grant from GlaxoSmithKline.

Link to full program: https://bit.ly/49YBZ4r

Link to downloadable slides: https://bit.ly/3GocjRe

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A Difficult Differential: Clinical Presentation and Diagnosis of RSV in Adults

support@deceraclinical.com (Angela Branche MD, Richard Zimmerman MD MPH FAAFP) — Thu, 30 Nov 2023 19:17:22 +0000

In this episode, Angela Branche, MD; Pamela Rockwell, DO, FAAFP; and Richard Zimmerman, MD, MPH, FAAFP, discuss the clinical presentation of RSV in older adults and available diagnostic tests for RSV, including:

Comparison of RSV clinical symptoms to influenza and COVID-19, including differentiating symptoms at infection onset
RSV disease progression
RSV diagnostic approaches
How RSV diagnosis of adults may differ from diagnosis of children
Clinical considerations for RSV testing
How to improve RSV awareness among patients

Program Director:

Pamela Rockwell, DO, FAAFP
Professor
Family Medicine
University of Michigan Medical School
Ann Arbor, Michigan

Faculty:

Angela Branche, MD
Associate Professor of Medicine
Division of Infectious Diseases
Department of Medicine
University of Rochester
Rochester, New York

Richard Zimmerman, MD, MPH, FAAFP
Professor
Department of Family Medicine and Clinical Epidemiology
University of Pittsburgh
Pittsburgh, Pennsylvania

Content based on an online CME program supported by an independent educational grant from GlaxoSmithKline.

Link to full program:
https://bit.ly/49YBZ4r

Link to downloadable slides:
https://bit.ly/3GocjRe

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Q&A on HIV PrEP: Episode 4 on Adolescents and Young Adults Part 2

support@deceraclinical.com (Samantha V Hill MD MPH, Eunice E Radcliff MD) — Thu, 30 Nov 2023 19:05:59 +0000

In this episode, Samantha V. Hill, MD, MPH, and Eunice E. Radcliff, MD, discuss key considerations for PrEP uptake in adolescents, including:

Advice on talking with parents about the importance of adolescents having alone time with their healthcare professionals
Maintaining confidentiality when someone is on their parents’ insurance
Strategies to increase awareness, uptake, engagement, and persistence on PrEP among adolescents
Having discussions about HIV prevention and PrEP along with the HPV vaccine, STI testing, or contraception

Faculty

Samantha V. Hill, MD, MPH
Assistant Professor
Division of General Pediatrics
Section on Adolescent Health
Department of Pediatrics
Emory University
Atlanta, Georgia

Eunice E. Radcliff, MD
Assistant Professor General Pediatrics
Emory University School of Medicine
Atlanta, Georgia

Link to full program: https://bit.ly/3PZGYdR

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Podcast on On-Demand PrEP: Strategies to Support PrEP Persistence and Reengagement

support@deceraclinical.com (Jean Michel Molina MD PhD) — Thu, 30 Nov 2023 18:30:19 +0000

In this episode, Jean-Michel Molina, MD, PhD, discusses the data and recommendations for considering on-demand PrEP as a strategy to support PrEP persistence and engagement for men who have sex with men, including:

Nondaily PrEP options recommended for cisgender men
Data from the ANRS IPERGAY study evaluating on-demand FTC/TDF vs placebo in men who have sex with men
Real-world data on the effectiveness of on-demand PrEP
Considerations for on-demand FTC/TDF in people with renal dysfunction
Data on hypertension and statin initiation risk with FTC/TAF PrEP
Data on weight gain with the different PrEP options

Faculty

Jean-Michel Molina, MD, PhD
Professor of Infectious Diseases
University of Paris Cité
Head of the Department of Infectious Diseases
Hospital Saint-Louis and Lariboisière
Paris, France

Follow along with the slides
https://bit.ly/47VGZVL

Link to full program:
https://bit.ly/3ZlICsL

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Role of Quantitative HBsAg Testing in Clinical Practice for People With CHB

Wed, 29 Nov 2023 20:56:57 +0000

Should quantitative HBsAg testing be used routinely in clinical practice for patients living with chronic hepatitis B?

In this episode, Tatyana Kushner, MD, MSCE, discusses the role of quantitative hepatitis B surface antigen testing in people living with chronic hepatitis B, including:

Determination of inactive carrier status
Prediction of liver fibrosis/cirrhosis
Prediction of hepatocellular carcinoma development
Monitoring response to treatment, including future HBV treatments in the development pipeline
Prediction of HBsAg loss

Joining her for the panel discussion are Ira M. Jacobson, MD, and Paul Y. Kwo, MD.

Presenters:

Ira M. Jacobson, MD
Professor of Medicine
Director of Hepatology
NYU Langone Health
New York, New York

Tatyana Kushner, MD, MSCE
Associate Professor
Division of Liver Diseases
Icahn School of Medicine at
Mount Sinai
New York, New York

Paul Y. Kwo, MD
Professor of Medicine
Director of Hepatology
Stanford University School of Medicine
Palo Alto, California

Link to the full program:
https://bit.ly/3R1PMi4

Link to the slides:
https://bit.ly/3N5Fpsm

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Which Patients With Hepatitis B Should We Be Treating?

support@deceraclinical.com (Tatyana Kushner MD MSCE, Paul Y Kwo MD) — Wed, 29 Nov 2023 19:58:51 +0000

Are we treating HBV early enough? Is it time to move the goalposts regarding the timing of treatment initiation? What are the potential benefits of earlier treatment?

To answer these questions, Ira M. Jacobson, MD, leads a panel discussion with Tatyana Kushner, MD, MSCE, and Paul Y. Kwo, MD, exploring which patients with HBV we should be treating, including a focus on:

Guideline-based treatment recommendations and their limitations
Data describing the relationship between viral suppression and HBV DNA integration
More expansive indications for HBV treatment based on virologic considerations

Presenters:

Ira M. Jacobson, MD
Professor of Medicine
Director of Hepatology
NYU Langone Health
New York, New York

Tatyana Kushner, MD, MSCE
Associate Professor
Division of Liver Diseases
Icahn School of Medicine at
Mount Sinai
New York, New York

Paul Y. Kwo, MD
Professor of Medicine
Director of Hepatology
Stanford University School of Medicine
Palo Alto, California

Link to the full program: https://bit.ly/3R1PMi4

Link to the slides: https://bit.ly/3N5Fpsm

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A Hidden Annual Epidemic: The Burden of RSV in Adults

Wed, 29 Nov 2023 19:37:37 +0000

In this episode, Angela Branche, MD; Pamela Rockwell, DO, FAAFP; and Rick Zimmerman, MD, MPH, FAAFP, discuss the burden of RSV in older adults, including:

RSV burden throughout life
RSV seasonality in the United States
Comparative burden and incidence of RSV and influenza in adults aged 65 years or older
Cardiopulmonary hospitalizations of long-term care facility residents with influenza and/or RSV
Risk factors for severe RSV (eg, hospitalization, mortality) in older adults
RSV incidence by presence of underlying medical conditions
RSV awareness among healthcare professionals and patients

Program Director:

Pamela Rockwell, DO, FAAFP
Professor
Family Medicine
University of Michigan Medical School
Ann Arbor, Michigan

Faculty:

Angela Branche, MD
Associate Professor of Medicine
Division of Infectious Diseases
Department of Medicine
University of Rochester
Rochester, New York

Richard Zimmerman, MD, MPH, FAAFP
Professor
Department of Family Medicine and Clinical Epidemiology
University of Pittsburgh
Pittsburgh, Pennsylvania

Content based on an online CME program supported by an independent educational grant from GlaxoSmithKline.

Link to full program: https://bit.ly/49YBZ4r

Link to downloadable slides: https://bit.ly/3GocjRe

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Podcast on Addressing Social Determinants: Strategies to Support PrEP Persistence and Reengagement

support@deceraclinical.com (Beatriz Grinsztejn MD PhD) — Tue, 28 Nov 2023 05:00:00 +0000

In this episode, Beatriz Grinsztejn, MD, PhD, discusses the data and recommendations for addressing social determinants as a strategy to support PrEP persistence and engagement for transgender women, including:

HIV prevalence among transgender women
Data on the PrEP cascade from the PrEParadas study of daily FTC/TDF among transgender women
Data from the ImPrEP Study on early loss to follow-up, adherence, long-term engagement, and HIV incidence among transgender women
Barriers to PrEP uptake and adherence for transgender women
Drug–drug interactions between PrEP and feminizing hormone therapy
Increasing PrEP uptake and retention with peer health navigation for transgender women

Faculty

Beatriz Grinsztejn, MD, PhD
Director
HIV/STI Clinical Research Laboratory
Instituto Nacional de Infectologia Evandro Chagas-Fiocruz
Rio de Janeiro, Brazil
IAS President-Elect

Link to full program:
https://bit.ly/3ZlICsL

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Trailblazers: Pharmacist’s Role in Optimizing New RSV Vaccines for Older Adults

Mon, 27 Nov 2023 15:30:00 +0000

In this accredited podcast episode, Dr Christina Madison and Dr Mary Bridgeman provide practical strategies for implementing RSV vaccination into practice, including:

Educating older adults on RSV vaccines
Providing effective, evidence-based recommendations
Shared decision-making
Identifying and addressing vaccine hesitancy
Proactive strategies in vaccinating for RSV
Predicting and overcoming barriers to RSV vaccination

Presenters:

Mary Barna Bridgeman, PharmD, BCPS, BCGP, FASCP, FCCP, FNAP
Clinical Professor
Ernest Mario School of Pharmacy
Rutgers, The State University of New Jersey
Piscataway, New Jersey
Internal Medicine Pharmacist
Robert Wood Johnson University Hospital
New Brunswick, New Jersey

Christina M. Madison, PharmD, FCCP, AAHIVP
Clinical Pharmacist
Founder and CEO, The Public Health Pharmacist, PLLC
Adjunct Associate Professor of Pharmacy Practice
Roseman University of Health Sciences
College of Pharmacy
Henderson, Nevada

Other program activities:

Frontiers in RSV Prevention for Older Adults: Developments, Recommendations, and the Pharmacist’s Role
https://bit.ly/49GUv1g

Link to CME: Claim Credit –
https://bit.ly/3uoY7VH

[After selecting the “Continue to Post Test” button:]

To receive continuing education credit, submit your posttest answers no later than the expiration of this activity. Select the best answer to each question. When you have completed all the questions, press the "Continue" button at the bottom.

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Light on the Horizon: Developments in RSV Vaccines

Tue, 21 Nov 2023 21:42:17 +0000

In this accredited podcast episode, Dr Christina Madison and Dr Mary Bridgeman discuss the latest practical strategies for preventing RSV infection in older adults, including:

Role of basic public health precautions
Available and emerging vaccines
Mechanisms of action, therapeutic targets, and pharmacology
Efficacy and safety data
FDA approval status and ACIP recommendations

Presenters:
Mary Barna Bridgeman, PharmD, BCPS, BCGP, FASCP, FCCP, FNAP
Clinical Professor
Ernest Mario School of Pharmacy
Rutgers, The State University of New Jersey
Piscataway, New Jersey
Internal Medicine Pharmacist
Robert Wood Johnson University Hospital
New Brunswick, New Jersey

Other program activities:

• Frontiers in RSV Prevention for Older Adults: Developments, Recommendations, and the Pharmacist’s Role

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Surveying the Landscape: Annual Burden of RSV in Older Adults

Tue, 21 Nov 2023 16:21:00 +0000

In this accredited podcast episode, Dr Mary Bridgeman discusses the most important things for pharmacists across all settings to know about RSV infections in patients 60 years of age or older, including:

Incidence and prevalence of RSV in older adults, including hospitalization, mortality, epidemiology
Seasonality
Clinical manifestations
Risk factors for severe outcomes
Vulnerable groups and comorbidities

Presenter:

Other program activities:

Frontiers in RSV Prevention for Older Adults: Developments, Recommendations, and the Pharmacist’s Role
https://bit.ly/49GUv1g

Link to CME: Claim Credit – https://bit.ly/47GtNnK

[After selecting the “Continue to Post Test” button:]

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Q&A on HIV PrEP: Episode 5 on Transgender Individuals and Racial and Ethnic Minority Men Who Have Sex With Men Part 2

support@deceraclinical.com (Aniruddha (Anu) Hazra MD, Ofole Mgbako MD) — Tue, 21 Nov 2023 05:00:00 +0000

In this episode, Aniruddha (Anu) Hazra, MD, and Ofole Mgbako, MD, discuss key considerations for PrEP uptake in transgender individuals and racial and ethnic minority men who have sex with men, including:

Data on drug–drug interactions between PrEP options and gender-affirming hormone therapy
Contributing factors to inequities in PrEP uptake for Black and Latino individuals
Data on FTC/TAF PrEP for transgender individuals
How to decide whether to do an oral lead-in before starting injectable cabotegravir PrEP
Time to effectiveness after starting PrEP
PrEP resources available for transgender communities, especially regarding stigma
Integration of PrEP with gender-affirming hormone therapy
Strategies to increase PrEP uptake, specifically in the south
Counseling patients on drug–drug interactions, adverse events, and transmission risk when starting PrEP
Involving PrEP navigators in the care of people receiving PrEP
Supporting PrEP adherence and retention in care
The use of DoxyPEP in transgender individuals receiving PrEP

Faculty

Aniruddha (Anu) Hazra, MD
Assistant Professor, Section of Infectious Disease and Global Health
Director, Infectious Diseases Fellowship Program
Medical Director, UCM Sexual Wellness Clinic
Director of STI Services, Chicago Center of HIV Elimination
Department of Medicine
University of Chicago
Chicago, Illinois

Ofole Mgbako, MD
Assistant Professor of Medicine and Population Health
Section Chief of Infectious Disease
Bellevue Hospital
Clinical Pillar Lead, NYU Institute for Excellence in Health Equity
NYU Grossman School of Medicine
NYU Langone Health
New York, New York

Link to full program: https://bit.ly/3PZGYdR

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NDM-Producing Enterobacterales: Applying Best Practices in Complex Clinical Scenarios

Thu, 16 Nov 2023 14:38:36 +0000

In this episode,Emily Heil, PharmD, MS, BCIDP, AAHIVP; Laila Woc-Colburn, MD; and Trevor Van Schooneveld, MD, FSHEA, FACP, discuss their approach to managing infections caused by NDM-producing Enterobacterales, including:

Ambler classification of β-lactamases
Mechanisms of resistance
2023 IDSA guidance recommendations
The latest clinical data by antimicrobial regimen:
Ceftazidime/avibactam and aztreonam
Cefiderocol
Investigational aztreonam/avibactam
Clinical case of NDM-producing E. coli with pan-β-lactam resistance

Program Director:

Trevor Van Schooneveld, MD, FSHEA, FACP
Professor, Division of Infectious Diseases
Program Director, Infectious Diseases Fellowship
Medical Director, Antimicrobial Stewardship Program
University of Nebraska Medical Center
Omaha, Nebraska

Faculty:

Emily Heil, PharmD, MS, BCIDP, AAHIVP
Associate Professor
Department of Pharmacy
University of Maryland
School of Pharmacy
ID Clinical Pharmacy Specialist
University of Maryland Medical Center
Baltimore, Maryland

Laila Woc-Colburn, MD
Associate Professor
Division of Infectious Diseases
Emory University School of Medicine
Atlanta, Georgia

Content based on a CME program supported by an educational grant from Merck & Co., Inc., Rahway, NJ, USA.

Follow along with a downloadable slideset at:
https://bit.ly/476v2wI

Link to full program:
https://bit.ly/40HyvPy

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DTR-Pseudomonas aeruginosa: Applying Best Practices in Complex Clinical Scenarios

Thu, 16 Nov 2023 14:31:25 +0000

In this episode, Emily Heil, PharmD, MS, BCIDP, AAHIVP; Laila Woc-Colburn, MD; and Trevor Van Schooneveld, MD, FSHEA, FACP, discuss their approach to managing infections involving Pseudomonas aeruginosa with difficult-to-treat resistance, including:

Mechanisms of β-lactam resistance
Effect of resistance mechanism on susceptibility to antipseudomonal agent
2023 IDSA guidance recommendations
Activity against newer antipseudomonal β-lactams in the United States
The latest clinical data by antimicrobial regimen:

- Ceftolozane/tazobactam
- Ceftazidime/avibactam
- Imipenem/cilastatin/relebactam
- Cefiderocol

Applying antimicrobial stewardship principles

Program Director:

Trevor Van Schooneveld, MD, FSHEA, FACP
Professor, Division of Infectious Diseases
Program Director, Infectious Diseases Fellowship
Medical Director, Antimicrobial Stewardship Program
University of Nebraska Medical Center
Omaha, Nebraska

Faculty:

Laila Woc-Colburn, MD
Associate Professor
Division of Infectious Diseases
Emory University School of Medicine
Atlanta, Georgia

Content based on a CME program supported by an educational grant from Merck & Co., Inc., Rahway, NJ, USA.

Follow along with a downloadable slideset at: https://clinicaloptions.com/CE-CME/infectious-disease/cmv-prevention-in-sot-recipients/26139

Link to full program: https://bit.ly/40HyvPy

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Carbapenem-Resistant Acinetobacter baumannii: Applying Best Practices in Complex Clinical Scenarios

Wed, 15 Nov 2023 19:12:08 +0000

In this episode, Emily Heil, PharmD, MS, BCIDP, AAHIVP; Laila Woc-Colburn, MD; and Trevor Van Schooneveld, MD, FSHEA, FACP, discuss their approach to managing infections involving carbapenem-resistant Acinetobacter baumannii (CRAB), including:

Mechanisms for β-lactam resistance
Additional resistance mechanisms and virulence factors
2023 IDSA guidance recommendations for moderate to severe CRAB infections
The latest clinical data by antimicrobial therapy/regimen:
Sulbactam
Meropenem and colistin
Carbapenem, sulbactam, and polymyxin B
Tetracyclines
Cefiderocol
Sulbactam/durlobactam and carbapenems

Program Director:

Faculty:

Laila Woc-Colburn, MD
Associate Professor
Division of Infectious Diseases
Emory University School of Medicine
Atlanta, Georgia

Content based on a CME program supported by an educational grant from Merck & Co., Inc., Rahway, NJ, USA.

Follow along with a downloadable slideset at:
https://bit.ly/476v2wI

Link to full program:
https://bit.ly/40Mmicz

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Where We’re Going: The Next Wave of Antiretroviral Innovations

Wed, 15 Nov 2023 05:00:00 +0000

In this second of 3 episodes, global HIV experts and advocates discuss how HIV care can better meet the diverse needs of people living with HIV as new treatment strategies emerge and continue to evolve, including:

How the emergence of long-acting injectable HIV treatment has been a game-changer for many people living with HIV
Emerging strategies that are expanding the application of long-acting ART to address unmet treatment needs
Potential for future innovations in ART that are hoped will further address unmet needs and preferences of people living with HIV

Faculty:

Ann Avery, MD
Professor of Medicine
Case Western Reserve University
Division of Infectious Diseases
MetroHealth Medical Center
Cleveland, Ohio

Jennifer Blanchette, PhD
Independent Contractor
Clinical Care Options
Colorado, United States

Isolde Butler, MD, MPH
Chief Medical Officer
CrescentCare
New Orleans, Louisiana

Monica Gandhi, MD, MPH
Professor of Medicine
Division of HIV, Infectious Diseases, and Global Medicine
Director, Center for AIDS Research (CFAR)
Medical Director, Ward 86 HIV Clinic
University of California, San Francisco (UCSF)
San Francisco, California

Marissa Gonzalez
Chair
Community Advisory Board
The Well Project

Angelina Namiba
Founder Member
4M Network of Mentor Mothers
London, United Kingdom

Chloe Orkin, MBChB, FRCP, MD
Professor of Infection and Inequities
Faculty of Medicine and Dentistry
Queen Mary University of London
Blizard Institute
Barts Health NHS Trust
London, United Kingdom

Link to full program:
https://bit.ly/3QFwv7n

Links to programs discussed in the episode:
www.4mmm.org

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PrEP Today: An HIV Prevention Revolution

Mon, 13 Nov 2023 17:55:19 +0000

In this episode, global PrEP experts and advocates discuss how current PrEP regimens represent a revolutionary step forward in enabling many individuals to avoid HIV acquisition, including:

How PrEP has empowered people to take control of their sexual lives, revolutionized people’s sexual experiences, and, for some, improved their experiences with healthcare in general
The extraordinary progress that has been made in New South Wales and specifically in inner Sydney toward HIV transmission elimination and the role of PrEP in the prevention of new HIV infections
The importance of having PrEP options, including on-demand options and long-acting formulations, available to different populations who could benefit to see progress toward HIV transmission elimination globally

Faculty:

Jessica L. Adams, PharmD, AAHIVE
Scientific Director, Infectious Diseases
Clinical Care Options
New York, United States

Linda-Gail Bekker, MBChB, DCH, DTM&H, FCP(SA), PhD
Professor and Director
The Desmond Tutu HIV Centre
University of Cape Town
South Africa
Chief Executive Officer
The Desmond Tutu Health Foundation
Cape Town, South Africa

Kenyon R. Farrow
PrEP Advocate
Vice President of Policy
Point Source Youth
Contributing Editor
TheBody.com
Ohio, United States

Beatriz Grinsztejn, MD, PhD
Director
STI/AIDS Clinical Research Laboratory
Instituto Nacional de Infectologia Evandro Chagas-Fiocruz
Rio de Janeiro, Brazil

Andrew Grulich, MBBS, PhD
Scientia Professor
Head, HIV Epidemiology and Prevention Program
The Kirby Institute
University of New South Wales, Sydney
New South Wales, Australia

Jean-Michel Molina, MD, PhD
Professor of Infectious Diseases
University of Paris Cité
Head of the Department of Infectious Diseases
Hospital Saint-Louis and Lariboisière
Paris, France

Brittany Williams, PhD
PrEP Advocate
Assistant Professor of Higher Education and Student Affairs Administration
Department of Education
University of Vermont
Vermont, United States

Link to full program:
https://bit.ly/3FbPBey

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Unlocking the Promise of PrEP and the Future of PrEP

Mon, 13 Nov 2023 17:52:42 +0000

In this episode, global PrEP experts and advocates discuss barriers that have prevented the full potential of today’s PrEP regimens from being delivered, how those barriers might be overcome, and how the next generation of PrEP modalities may address unmet needs, including:

How access and implementation of PrEP have limited its benefit and led to disparities in uptake among racial and ethnic groups in the United States and among key populations globally
The challenges of adherence to PrEP for healthy individuals who are required to consistently take medication and engage with the healthcare system when they aren’t sick
The potential for longer-acting PrEP modalities and a greater number of PrEP options for individuals in the future to expand PrEP uptake and adherence with equitable global access

Faculty:

Jessica L. Adams, PharmD, AAHIVE
Scientific Director, Infectious Diseases
Clinical Care Options
New York, United States

Kenyon R. Farrow
PrEP Advocate
Vice President of Policy
Point Source Youth
Contributing Editor
TheBody.com
Ohio, United States

Beatriz Grinsztejn, MD, PhD
Director
STI/AIDS Clinical Research Laboratory
Instituto Nacional de Infectologia Evandro Chagas-Fiocruz
Rio de Janeiro, Brazil

Brittany Williams, PhD
PrEP Advocate
Assistant Professor of Higher Education and Student Affairs Administration
Department of Education
University of Vermont
Vermont, United States

Link to full program:
https://bit.ly/3FbPBey

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Updates in Antimicrobial Selection for uUTIs

support@deceraclinical.com (Lillian Abbo MD MBA FIDSA) — Mon, 13 Nov 2023 05:00:00 +0000

In this episode, Lillian Abbo, MD, MBA, FIDSA, discusses appropriate antimicrobial selection for managing uncomplicated UTIs, including:

Balancing discrepancies in available guidelines
Individualizing antimicrobial selection based on patient characteristics and local resistance patterns
Incorporating tools, like antibiograms, into daily practice
Being a good steward of currently available antimicrobial agents
Planning ahead for emerging therapies for uncomplicated UTIs

Presenter:

Lillian Abbo, MD, MBA, FIDSA
Associate Chief Medical Officer
Infectious Diseases
Jackson Health System
Professor of Clinical Infectious Diseases
University of Miami Miller School of Medicine
Miami Transplant Institute
Miami, Florida

Find other program activities here:

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Best Practices in Managing Uncomplicated UTIs in the Emergency Department

support@deceraclinical.com (Lilly C. Lee MD SM FACEP FAAEM) — Mon, 13 Nov 2023 05:00:00 +0000

In this episode, Lilly C. Lee, MD, SM, FACEP, FAAEM, discusses the best practices in management of uUTI in the emergency department, including:

Patient triage
Diagnostic stewardship
Interdisciplinary care
Strategies to overcome treatment barriers

Presenter:

Lilly C. Lee, MD, SM, FACEP, FAAEM
Chief of Emergency Medicine
Jackson Memorial Hospital
Florida Poison Information Center
Roxcy Bolton Rape Treatment Center
Affiliated Assistant Professor of Surgery
DeWitt Daughtry Family Department of Surgery
Leonard M. Miller School of Medicine
University of Miami
Miami, Florida

Find other program activities here:

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Burden of Uncomplicated Urinary Tract Infections

support@deceraclinical.com (Richard Colgan MD) — Mon, 13 Nov 2023 05:00:00 +0000

In this episode, Richard Colgan, MD, discusses the burden of uncomplicated UTIs (uUTIs) and best practices in their management, including:

Accurate diagnosis and classification
Risk factors for uUTIs and treatment failure
Burdens of uUTIs on patients
Innovations in care, including self-diagnosis and virtual management
The importance of avoiding screening and management of asymptomatic bacteriuria in most patients

We will also hear from a patient who details the impact of uUTI on her quality of life.

Presenter:

Richard Colgan, MD

Executive Vice Chair
Professor of Family and Community Medicine
University of Maryland School of Medicine
Baltimore, Maryland

Find other program activities here:

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Frequently Asked Questions About CMV Management

Mon, 6 Nov 2023 19:45:16 +0000

In this episode, Atul Humar, MD, FRCP(C); Hannah Imlay, MD, MS; and Raymund Razonable, MD, discuss cytomegalovirus (CMV) management strategies in solid organ transplantation recipients, including:

Evaluation of current data on CMV prevention in liver transplant recipients
Practical considerations for switching an institution’s antiviral therapy of choice for primary prophylaxis
Barrier of resistance to antiviral therapies
Factors to consider when deciding CMV treatment duration
Use of lymphocyte count to assess CMV cell–mediated immunity

Program Director:

Atul Humar, MD, FRCP(C)
Professor of Medicine
University of Toronto
Director, Ajmera Transplant Centre
University Health Network
R. Fraser Elliott Chair in Transplantation
Director University of Toronto Transplant Institute
Toronto, Ontario, Canada

Faculty:

Hannah Imlay, MD, MS
Assistant Professor of Medicine
Department of Internal Medicine, Division of Infectious Diseases
University of Utah
Salt Lake City, Utah

Raymund Razonable, MD
Professor of Medicine
Program Director, Infectious Diseases Fellowship
Vice Chair, Division of Infectious Diseases
Mayo Clinic
Rochester, Minnesota

Content based on a CME program supported by an educational grant from Merck & Co., Inc., Rahway, NJ, USA.

Follow along with a downloadable slideset at:
https://bit.ly/476v2wI

Link to full program:
https://bit.ly/47lNK2K

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Modernizing CMV Preventive Approaches

support@deceraclinical.com (Hannah Imlay MD MS) — Mon, 6 Nov 2023 17:05:12 +0000

In this episode, Hannah Imlay, MD, MS, discusses cytomegalovirus (CMV) prevention strategies in solid organ transplantation (SOT) recipients including:

Strategies for preventing CMV in SOT
International guideline recommendations for CMV prevention strategies by organ type
Antivirals used for CMV prevention
Comparison of preemptive therapy vs prophylaxis for CMV prevention in liver transplant recipients
Comparison of letermovir vs valganciclovir for CMV prophylaxis in kidney transplant recipients
Use of CMV cell–mediated immunity monitoring for primary prophylaxis
Monitoring CMV viral loads, including limitations to quantitative nucleic acid testing
Future prevention approaches

Faculty:

Hannah Imlay, MD, MS
Assistant Professor of Medicine
Department of Internal Medicine, Division of Infectious Diseases
University of Utah
Salt Lake City, Utah

Content based on a CME program supported by an educational grant from Merck & Co., Inc., Rahway, NJ, USA.

Follow along with a downloadable slideset at:
https://bit.ly/476v2wI

Link to full program:
https://bit.ly/47lNK2K

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Beyond CMV Prevention

support@deceraclinical.com (Raymund Razonable MD) — Mon, 6 Nov 2023 17:04:15 +0000

In this episode, Raymund Razonable, MD, discusses cytomegalovirus (CMV) management strategies beyond primary prophylaxis in solid organ transplantation recipients including:

CMV treatment goals
CMV treatment and monitoring recommendations
Role of secondary prophylaxis
Use of CMV cell–mediated immunity (CMI) monitoring for CMV relapse risk
Use of CMV CMI for secondary prophylaxis
Proposed use of CMV CMI monitoring for secondary prophylaxis
Incidence and outcomes with antiviral resistance
Risk factors for CMV resistance
When to suspect antiviral resistance
Testing for antiviral resistance using genotypic assays
Outcomes in patients with ganciclovir-resistant vs ganciclovir-susceptible virus
Treatment recommendations for resistant/refractory CMV
Efficacy and safety of maribavir vs investigator-assigned therapy for resistant/refractory CMV infections from the phase III SOLTICE study
Treatment algorithm for resistant/refractory CMV
Adjunctive, investigational, and off-label treatment options for resistant/refractory CMV

Faculty:

Raymund Razonable, MD
Professor of Medicine
Program Director, Infectious Diseases Fellowship
Vice Chair, Division of Infectious Diseases
Mayo Clinic
Rochester, Minnesota

Content based on a CME program supported by an educational grant from Merck & Co., Inc., Rahway, NJ, USA.

Follow along with a downloadable slideset at:
https://bit.ly/476v2wI

Link to full program:
https://bit.ly/47lNK2K

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COVID-19 Update: Independent Conference Coverage of IDWeek 2023

support@deceraclinical.com (Aruthur Kim MD, Renslow Sherer MD) — Mon, 6 Nov 2023 16:47:06 +0000

Arthur Kim, MD, and Renslow Sherer, MD, discuss how new data on COVID-19 vaccines and treatments may affect practice, including:

Real-world data on COVID-19 outcomes
COVID-19 prevention: current and emerging concepts
COVID-19 therapeutics: new clinical trial and real-world data

Presenters:

Arthur Kim, MD
Associate Professor of Medicine
Harvard Medical School
Division of Infectious Diseases
Massachusetts General Hospital
Boston, Massachusetts

Renslow Sherer, MD
Director
International HIV Training Center
Professor of Medicine
Section of Infectious Diseases and Global Health
Department of Medicine
University of Chicago
Chicago, Illinois

Follow along with the slides at:
https://bit.ly/40DFjhv

Link to full program:
https://bit.ly/3FI8HJx

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Where We Are: Innovations in HIV Care Delivery

support@deceraclinical.com (Decera Clinical Education) — Wed, 1 Nov 2023 17:05:38 +0000

In this first of 3 episodes, global HIV experts and advocates discuss how innovative models of care are minimizing barriers to HIV care engagement to improve uptake by key underserved populations, including:

How peer support programs empower people to combat stigma, become more educated about treatment, and be engaged participants in their HIV care
Strategies for addressing potential unmet mental healthcare needs among people living with HIV
Approaches to reengage people with HIV who transit through county jail systems
How integrated care strategies and wrap-around services can overcome some of the barriers to care that are associated with social determinants of health
Key considerations when providing HIV care for migrant and refugee populations

Faculty:

Ann Avery, MD
Professor of Medicine
Case Western Reserve University
Division of Infectious Diseases
MetroHealth Medical Center
Cleveland, Ohio

Jennifer Blanchette, PhD
Independent Contractor
Clinical Care Options
Colorado, United States

Isolde Butler, MD, MPH
Chief Medical Officer
CrescentCare
New Orleans, Louisiana

Marissa Gonzalez
Chair
Community Advisory Board
The Well Project

Angelina Namiba
Founder Member
4M Network of Mentor Mothers
London, United Kingdom

Miłosz Parczewski, MD, PhD
Professor of Medicine
Department Head
Consultant in Infectious Diseases
Department of Infectious, Tropical Diseases and Acquired Immunodeficiency
Pomeranian Medical University
Szczecin, Poland

Link to full program:
https://bit.ly/3QFwv7n

Links to programs discussed in the episode:
https://4mmm.org/
https://positivepeers.org/

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Emerging Scientific Data and Unique Clinical Scenarios in People With NTM Lung Disease

Tue, 31 Oct 2023 16:03:48 +0000

In this episode, Shannon Kasperbauer, MD, discusses guideline-based treatment recommendations for people with M. abscessus, including a discussion of:

Macrolide resistance
Predictors for disease progression
2020 NTM guideline recommended treatment options
Emerging therapies

We will also hear from a patient who describes how she remained adherent during long courses of treatment for M. abscessus.

Finally, we hear Dr Kasperbauer discuss a patient case with her colleagues, Charles L. Daley, MD, and Pamela J. McShane, MD.

Presenters:

Charles L. Daley, MD
Professor of Medicine
Division of Mycobacterial and Respiratory Infections
National Jewish Health
Denver, Colorado

Shannon Kasperbauer, MD
Associate Professor of Medicine
Division of Mycobacterial and Respiratory Infections
National Jewish Health
Denver, Colorado

Pamela J. McShane, MD
Professor of Medicine
Division of Pulmonary and
Critical Care Medicine
The University of Texas Health Science Center at Tyler
Tyler, Texas

Link to program page: https://bit.ly/3QzJo2B

Link to downloadable slides: https://bit.ly/3Qh8T7G

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Guidelines-Based Treatment for NTM Lung Disease: Application in Complex Patients

Tue, 31 Oct 2023 15:33:31 +0000

In this episode, Charles L. Daley, MD, discusses guideline-based treatment recommendations for nontuberculous mycobacterial (NTM) lung disease, including treatment regimens for:

Mycobacterium avium complex
M. kansasii
M. xenopi

We will also hear from a patient who describes the use of airway clearance devices and a patient who describes his typical NTM treatment course.

Finally, we hear Dr. Daley discuss a patient case with his colleagues, Shannon Kasperbauer, MD, and Pamela J. McShane, MD.

Presenters:

Charles L. Daley, MD

Professor of Medicine
Division of Mycobacterial and Respiratory Infections
National Jewish Health
Denver, Colorado

Shannon Kasperbauer, MD

Associate Professor of Medicine
Division of Mycobacterial and Respiratory Infections
National Jewish Health
Denver, Colorado

Pamela J. McShane, MD

Professor of Medicine
Division of Pulmonary and
Critical Care Medicine
The University of Texas Health Science Center at Tyler
Tyler, Texas

Link to program page: https://bit.ly/3QzJo2B

Link to downloadable slides: https://bit.ly/3Qh8T7G

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Diagnosis of NTM Lung Disease: Art and Science

support@deceraclinical.com (Pamela J. McShane MD) — Tue, 31 Oct 2023 15:09:00 +0000

In this episode, Pamela J. McShane, MD, describes the 3 pillars for nontuberculous mycobacterial (NTM) lung disease diagnosis:

Clinical symptoms
Radiographic evidence
Microbiologic data

We will also hear from a patient who details his diagnostic journey and will hear Dr. McShane discuss an illustrative clinical case.

Presenter:
Pamela J. McShane, MD
Professor of Medicine
Division of Pulmonary and
Critical Care Medicine
The University of Texas Health Science Center at Tyler
Tyler, Texas

Link to program page: https://bit.ly/3QzJo2B

Link to downloadable slides: https://bit.ly/3Qh8T7G

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Barriers to HIV PrEP in Cisgender Women

support@deceraclinical.com (David Alain Wohl MD) — Mon, 23 Oct 2023 12:04:27 +0000

In this episode, David Alain Wohl, MD, discusses key considerations to PrEP barriers in cisgender women, including:

Prevalence of PrEP use in the US
Barriers to PrEP uptake
PrEP efficacy based on adherence
Interventions to support PrEP adherence
Recommended PrEP regimens, including considerations for use in pregnancy and breastfeeding

Presenter:

David Alain Wohl, MD
Professor of Medicine
School of Medicine
Site Leader, Global Infectious Diseases Clinical Trials Unit
University of North Carolina at
Chapel Hill
Chapel Hill, North Carolina

Content based on an online CME program supported by an independent educational grant from ViiV Healthcare.

Link to full program: https://bit.ly/3ZpM6uu

Follow along with the slides: https://bit.ly/3LyGgBj

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Q&A on HIV PrEP: Episode 3 on Adolescents and Young Adults

support@deceraclinical.com (Sarah M Wood MD MS, Errol L Fields MD PhD MPH) — Mon, 23 Oct 2023 11:21:46 +0000

In this podcast, experts Sarah M. Wood, MD, MS, and Errol L. Fields, MD, PhD, MPH, discuss some of the challenges and concerns clinicians face when prescribing PrEP to adolescents.

The faculty addresses the potential for adverse effects from PrEP, including the potential for renal impairment, decreased bone density, and whether PrEP can interfere with hormone therapy for gender-affirming care. They review the data behind these concerns and emphasize that the vast majority of adverse effects caused by PrEP are mild and reversible.

The experts also examine common barriers that adolescents face when attempting to initiate and adhere to PrEP, such as insurance coverage and confidentiality. Dr Fields and Dr Woods discuss strategies for overcoming these barriers and retaining adolescents on PrEP, including how to navigate tricky conversations with both patients and parents or within communities that may stigmatize PrEP and HIV.

Sarah M. Woods, MD, MS
Assistant Professor of Pediatrics
Division of Adolescent Medicine
University of Pennsylvania Perelman School of Medicine
Children’s Hospital of Philadelphia
Philadelphia, Pennsylvania

Errol L. Fields, MD, PhD, MPH
Associate Professor of Pediatrics
Division of Adolescent/Young Adult Medicine
Department of Pediatrics
Johns Hopkins School of Medicine
Baltimore, Maryland

Content based on an online CME program supported by independent educational grants from Gilead Sciences Inc. and ViiV Healthcare.

Link to full program:
https://bit.ly/3PZGYdR

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Patient Perspectives on Barriers and Facilitators of HIV Care

support@deceraclinical.com (Melanie Reese, Marc Thompson) — Wed, 18 Oct 2023 14:25:51 +0000

In this episode, we hear from 2 people living with HIV: Melanie Reese from the United States and Marc Thompson from the United Kingdom. Both Melanie and Marc have done important work in the HIV field as patient advocates. Today, they will be discussing their experiences in accessing and navigating their own HIV care, with a focus on some of the barriers that can complicate and even block a person's journey across the HIV care continuum. In reviewing these challenges, Marc and Melanie share their insights on key strategies that can help to facilitate HIV care for patients, making the experience more straightforward and minimizing the impact that HIV has on their daily lives.

Presenters:

Melanie Reese
Subject Matter Expert, Older Women Living and Aging with HIV, HIV North America Health Resources and Services Administration HIV/AIDS Bureau
Executive Director, Older Women Embracing Life
Board Secretary, International Community of Women Living with HIV
Baltimore, Maryland

Marc Thompson
Director, The Love Tank
Co-founder, Prepster
London, England

Content based on an online CME/CPE/CE program supported by an independent educational grant from Gilead Sciences, Inc.

Link to full program:
https://bit.ly/3Pas4zn

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Podcast 2: Managing COVID-19 Risk in Individuals With Metabolic Syndrome and Obesity

support@deceraclinical.com (Rasika Karnik MD MS) — Fri, 6 Oct 2023 04:00:00 +0000

In this podcast, expert Rasika Karnik, MD, MS, discusses how to manage the health risks posed by COVID-19 infection and long COVID in individuals with metabolic syndrome or obesity.

Dr Karnik discusses the interplay between COVID-19 outcomes, obesity/metabolic syndrome, and social determinants of health and delves into detail on how to address and mitigate these social determinants of health in a high-risk population.

Presenters:
Rasika Karnik, MD, MS
Assistant Professor
Division of Primary Care,
Department of Internal Medicine
University of Chicago
Chicago, Illinois

Content based on an online CME program supported by independent educational grants from Pfizer.

Link to full program:
https://bit.ly/46yuChS

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Podcast 1: Managing COVID-19 Risk in Individuals With Metabolic Syndrome and Obesity

support@deceraclinical.com (Donna Ryan MD, Renslow Sherer MD) — Mon, 2 Oct 2023 04:00:00 +0000

In this podcast, experts Donna Ryan, MD, and Renslow Sherer, MD, discuss how to manage the health risks posed by COVID-19 infection and long COVID in individuals with metabolic syndrome or obesity.

First, Dr Ryan presents an overview of the relationship between COVID-19 and weight, including the mechanisms of how obesity may drive COVID-19 disease and how COVID-19 may in turn worsen obesity, through both immunologic and social or societal drivers.Dr Ryan also discusses the relationship between obesity and the risk for long COVID.

In his segment, Dr Sherer discusses COVID-19 vaccination and antiviral therapy within the context of obesity and metabolic syndrome. Dr Sherer also delves into detail on how obesity-related risk factors or comorbidities may affect treatment decisions and presents strategies on individualizing treatment, including in patients with long COVID.

This episode includes results from several reviews and meta-analyses examining the relationship between vaccination, as well as an observational study investigating the impact of nirmatrelvir/ritonavir therapy on long COVID in vaccinated patients.

Presenters:

Donna Ryan, MD
Professor Emerita
Pennington Biomedical Research Center
New Orleans, Louisiana

Renslow Sherer, MD
Director of the International HIV Training Center
Professor of Medicine
Infectious Diseases and Global Health
Department of Medicine University of Chicago Department of Medicine
Chicago, Illinois

Content based on an online CME program supported by independent educational grants from Pfizer.

Link to full program:
https://bit.ly/46yuChS

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Q&A on HIV PrEP: Episode 2 on Cisgender Women

support@deceraclinical.com (Oni Blackstock MD MHS, Whitney Irie MSW PhD) — Wed, 27 Sep 2023 11:48:10 +0000

In this episode, Oni Blackstock, MD, MHS, and Whitney Irie, MSW, PhD, discuss key considerations for PrEP uptake in cisgender women, including:

Ways to perform a nonintimidating sexual history
How to incorporate conversations on PrEP during a short clinic visit
Discussing adverse events associated with PrEP options with patients
Considerations for PrEP in women wanting to conceive
How patients can navigate obtaining PrEP in areas with limited healthcare resources
Guideline recommendation updates on PrEP eligibility
Use of wrap-around services
Interventions to improve PrEP access (eg, telehealth, nurse-led PrEP)

Faculty

Oni Blackstock, MD, MHS
Founder & Executive Director
Health Justice
New York, New York

Whitney Irie, MSW, PhD
Assistant Professor
Department of Social Work
Boston College
Brighton, Massachusetts

Link to full program: https://bit.ly/3PZGYdR

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Barriers to HIV PrEP in Adolescents

support@deceraclinical.com (Roger Bedimo MD MS FACP) — Thu, 21 Sep 2023 20:30:00 +0000

In this episode, Roger Bedimo, MD, MS, FACP, discusses key considerations to PrEP barriers in adolescents, including:

New HIV diagnoses in the United States
Adherence barriers
Healthcare professional barriers
Consent laws for minors to receive sexually transmitted infection diagnosis and treatment services
Interventions to support PrEP adherence

Presenter:

Roger Bedimo, MD, MS, FACP
Professor of Medicine
Division of Infectious Diseases
University of Texas UT Southwestern Medical Center
Section Chief
Department of Internal Medicine
VA North Texas Health Care System
Dallas, Texas

Content based on an online CME program supported by an independent educational grant from ViiV Healthcare.

Link to full program:
https://bit.ly/3ZpM6uu

Follow along with the slides:
https://bit.ly/3LyGgBj

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Integrating New Data on HIV Adverse Events From IAS 2023: Pharmacist Perspectives

Fri, 15 Sep 2023 17:49:13 +0000

In this episode, Brooke Bates, PharmD, BCPS, AAHIVP, and Neha Sheth Pandit, PharmD, AAHIVP, BCPS, discuss the most clinically relevant studies on HIV adverse events presented at IAS 2023, including:

REPRIEVE study of pitavastatin for cardiovascular prevention in people living with HIV at low to moderate cardiovascular risk
Data on weight change with switch from integrase inhibitor–based ART to doravirine/islatravir in the P017 and P018 studies
DEFINE study evaluating weight change after a switch to DRV/COBI/FTC/TAF in people living with HIV who experienced weight gain with integrase inhibitor–based ART

Faculty:

Brooke Bates, PharmD, BCPS, AAHIVP
Specialty Pharmacy Clinical Manager
Pediatric HIV Clinical Pharmacist
Indiana University Health
Indianapolis, Indiana

Neha Sheth Pandit, PharmD, AAHIVP, BCPS
Professor
Vice Chair for Research and Scholarship
Department of Practice, Sciences, and Health Outcomes Research
School of Pharmacy
University of Maryland
Clinical Pharmacist
THRIVE Program
Baltimore, Maryland

Link to full program:
https://bit.ly/3ZjSFhg

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Effective Patient‒Provider Communication for PrEP Persistence

support@deceraclinical.com (Tony Brown MPH) — Thu, 14 Sep 2023 14:51:31 +0000

In this episode, Tony Brown, MPH, discusses the importance of effective patient‒provider communication in supporting PrEP persistence including:

His own experience with PrEP and reasons for fluctuations in adherence over the years
The importance of open, honest, and judgement-free conversations about sexual health
Engaging patients in conversations about PrEP effectiveness, adverse effects, and changing life circumstances
Working together to find the most effective PrEP option for each individual patient that will help them to persist on PrEP long term

Faculty:

Tony Brown, MPH
PrEP User and Advocate
Doctoral Candidate
Health Services Policy and Management
University of South Carolina
Columbia, South Carolina

Link to full program: https://bit.ly/3ZlICsL

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Health-Related Quality of Life in People Living With HIV

Tue, 12 Sep 2023 04:00:00 +0000

In this episode, Nikos Dedes, Jeff Taylor, and Bernadette Sharp—people living with HIV—discuss how switching to long-acting ART has affected their quality of life. They are joined by 2 healthcare professionals—Iskandar Azwa,MBChB, MRCP, and Beng Eu, MBBS—who provide insights on how they assess and document health-related quality of life for their patients. The discussion focuses on personal experiences with how LA ART has improved health-related quality of life, including:

Avoidance of drug–drug interactions
Improved confidentiality
Decreased stigma

Presenters:

Iskandar Azwa, MBChB, MRCP
Associate Professor
Infectious Diseases
Faculty of Medicine
University of Malaya
Kuala Lumpur, Malaysia

Nikos Dedes
Positive Voice
Athens, Greece

Beng Eu, MBBS
Doctor
Prahran Market Clinic
Melbourne, Victoria, Australia

Bernadette Sharp
Advocate

Jeff Taylor
Executive Director
HIV+Aging Research Project
Palm Springs, California

Content based on an online CME program supported by an independent educational grant from ViiV Healthcare.ViiV Healthcare was not involved in the development of content or selection of faculty for this educational activity.

Link to downloadable slides:
https://bit.ly/488WwT7

Link to full program:
bit.ly/3EwEnRJ

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Answering the Questions on Which HIV PrEP for Which Patient: Jill Blumenthal and Kenric Ware

Tue, 12 Sep 2023 04:00:00 +0000

In this episode, Jill Blumenthal, MD, MAS, and Kenric B. Ware, PharmD, MBA, AAHIVP, answer questions about HIV PrEP including:

Considerations for selecting between oral and injectable PrEP in college students
Strategies to promote PrEP persistence in adolescents
Best approaches to address readiness to start PrEP in adolescents (eg, creating nonjudgmental environments, addressing misconceptions)
Considerations for local consent laws
Available data on PrEP young adolescents (eg, age and weight limits)
Initiatives in place to address racial and ethnic disparities associated with PrEP uptake and persistence
The role of on-demand PrEP in transgender individuals receiving gender-affirming hormone therapy
Offering patient-centered care
Educating healthcare professionals on how to prescribe PrEP

Faculty:

Jill Blumenthal, MD, MAS
Associate Professor of Medicine
Division of Infectious Diseases and Global Public Health
Department of Medicine
University of California, San Diego
San Diego, California

Kenric B. Ware, PharmD, MBA, AAHIVP
Clinical Associate Professor
Department of Pharmacy Practice
Mercer University College of Pharmacy
Atlanta, Georgia

Link to full program:
https://bit.ly/3Fqdgs9

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What Challenges and Opportunities Exist With Implementation of Available Long-Acting ART?

Mon, 11 Sep 2023 04:00:00 +0000

In this episode, Iskandar Azwa, MBChB, MRCP; Nikos Dedes; Beng Eu, MBBS; Bernadette Sharp; and Jeff Taylor discuss challenges and opportunities with long-acting ART implementation, including:

Personal experiences with receiving LA ART
Views on long-acting ART in the development pipeline
Perspectives on self-administration of LA ART

Presenters:

Iskandar Azwa, MBChB, MRCP
Associate Professor
Infectious Diseases
Faculty of Medicine
University of Malaya
Kuala Lumpur, Malaysia

Nikos Dedes
Positive Voice
Athens, Greece

Beng Eu, MBBS
Doctor
Prahran Market Clinic
Melbourne, Victoria, Australia

Bernadette Sharp
Advocate

Jeff Taylor
Executive Director
HIV+Aging Research Project
Palm Springs, California

Content based on an online CME program supported by an independent educational grant from ViiV Healthcare. ViiV Healthcare was not involved in the development of content or selection of faculty for this educational activity.

Link to downloadable slides: https://clinicaloptions.com/CE-CME/infectious-disease/slides-fourth-90-and-la-art/17553-25368

Link to full program: https://bit.ly/3EwEnRJ

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Q&A on HIV PrEP: Episode 1 on Transgender Individuals and Racial and Ethnic Minority Men Who Have Sex With Men

support@deceraclinical.com (Raphael J Landovitz MD MSC, Hyman Scott MD MPH) — Fri, 8 Sep 2023 12:13:54 +0000

In this episode, Raphael J. Landovitz, MD, MSc, and Hyman Scott, MD, MPH, discuss key considerations for PrEP uptake in transgender individuals and racial and ethnic minority men who have sex with men, including:

Misconceptions about PrEP eligibility
Strategies to improve lab monitoring on PrEP
Leveraging patient navigators and clinic staff to expand PrEP access
Data on PrEP efficacy in key populations (eg, transgender men, people who inject drugs)
Considerations for prescribing on-demand and same-day PrEP
Addressing healthcare professional hesitancy to prescribe PrEP
US Preventive Services Task Force PrEP guideline updates
Bundling sexually transmitted infection services with PrEP

Faculty

Raphael J. Landovitz, MD, MSc
Professor of Medicine
Division of Infectious Diseases
David Geffen School of Medicine
University of California, Los Angeles
Director, UCLA Center for Clinical AIDS Co-Director, Center for HIV Identification, Prevention, and Treatment Services
Los Angeles, California

Hyman Scott, MD
Assistant Clinical Professor
Department of Medicine
University of California, San Francisco
Clinical Research Medical Director
Bridge HIV
San Francisco Department of
Public Health
San Francisco, California

Link to full program:
https://bit.ly/3PZGYdR

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RSV Recommendations From ACIP: How to Apply Them in Your Older Adults

support@deceraclinical.com (Angela Branche MD) — Fri, 8 Sep 2023 12:05:59 +0000

In this episode, Angela Branche, MD, discusses the Advisory Committee on Immunization Practices recommendations for RSV vaccines in older adults, including:

Use of shared clinical decision-making
How to approach the conversation about the RSV vaccine with patients
Key populations who may benefit the most, such as those at risk for severe RSV disease (eg, increasing age and persons who are frail or have cardiopulmonary comorbidities)

Faculty:

Angela Branche, MD

Associate Professor of Medicine
Division of Infectious Diseases
Department of Medicine
University of Rochester
Rochester, New York

Link to full program: https://bit.ly/3nb25xe

Link to downloadable slides: https://bit.ly/3nb25xe

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Challenging Scenarios: Managing Virologic Failure in a Heavily Treatment–Experienced Patient

support@deceraclinical.com (Renslow Sherer MD) — Tue, 22 Aug 2023 13:25:07 +0000

In this episode, Renslow Sherer, MD, discusses managing virologic failure in a person living with HIV who is heavily treatment experienced, including:

Guideline recommendations for selecting a new ART regimen
Options for patients with multidrug-resistant HIV from existing drug classes and novel mechanisms of action with no cross-resistance
Data from TMB-301 and TMB-311 for ibalizumab, BRIGHTE for fostemsavir, and CAPELLA for lenacapavir on the use of these agents for people living with HIV who are heavily treatment experienced with multidrug-resistant HIV

Presenter:

Renslow Sherer, MD
Director
International HIV Training Center
Professor of Medicine
Section of Infectious Diseases and Global Health
Department of Medicine
University of Chicago
Chicago, Illinois

To download the slides:
https://bit.ly/3OcqxIE

To view the full online program:
https://bit.ly/3ZjSFhg

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PrEP Talks: Uptake in Cisgender Women

support@deceraclinical.com (Oni Blackstock MD MHS, Brittany Williams PhD) — Tue, 8 Aug 2023 17:00:20 +0000

In this episode, Oni Blackstock, MD, MHS, and Brittany Williams, PhD,discuss key considerations to pre-exposure prophylaxis (PrEP) uptake in cisgender women, including:

The misconception by patients and healthcare professionals (HCP) that cisgender women are at low risk for HIV
Reframing HIV prevention from “risks” to “reasons” such as promoting self-care and taking control of one’s own sexual health
CDC PrEP guidance recommendations
Increasing PrEP awareness by sharing PrEP experiences with others in the community
The importance of community representation in PrEP marketing and campaigns
Challenges with finding HCPs who prescribe PrEP for cisgender women
Promoting self-advocacy when seeking care, including HIV prevention
Strategies for patients to engage with their HCPs to learn about and obtain PrEP
Available resources for PrEP coverage

Faculty:

Oni Blackstock, MD, MHS
Founder & Executive Director

Health Justice

New York, New York

Brittany Williams, PhD
Assistant Professor of Higher Education and Student Affairs Administration

Department of Education

University of Vermont

Burlington, Vermont

Link to full program: https://bit.ly/3PZGYdR

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Long-Acting Lipoglycopeptides for Skin and Soft Tissue Infections : Implementation Into Practice

support@deceraclinical.com (Kyle Molina PharmD BCIDP) — Tue, 8 Aug 2023 16:55:29 +0000

In this episode, Kyle Molina, PharmD, BCIDP, discusses key considerations for successful implementation of long-acting lipoglycopeptides into clinical practice. Listen as he gives perspectives on:

Reasons to consider use of long-acting lipoglycopeptides (eg, poor adherence to oral antibiotics, PICC-related costs and complications)
Data supporting and challenging cost effectiveness of long-acting lipoglycopeptides
Identifying the target patient population
Selecting the right location to provide long-acting lipoglycopeptides
Strategies to maximize institutional impact with key stakeholders (eg, hospital avoidance, reduced ED and hospital length of stay)
Key characteristics of available long-acting lipoglycopeptides
Addressing logistical challenges, including navigating the reimbursement process

Faculty:

Kyle Molina, PharmD, BCIDP
Infectious Diseases Clinical Pharmacist
Scripps Green Hospital
La Jolla, California

Link to full program:

CCO: https://bit.ly/3J4mg8h
ProCE: https://bit.ly/3P0vB4E

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People of Childbearing Potential and Their Infants: Overcoming HBV Barriers

support@deceraclinical.com (Joseph Ahn MD MS MBA, Christina Delacruz Leyson MD) — Thu, 3 Aug 2023 19:56:54 +0000

In this episode, Joseph Ahn, MD, MS, MBA; Christina Delacruz Leyson, MD; and Alice Chan, a person who experienced pregnancy as a person living with chronic hepatitis B, discuss solutions for overcoming barriers to HBV care in people of childbearing potential and their infants, including:

HBV screening and vaccination in pregnancy
Management of pregnant people who are HBsAg positive
Infant care
Breastfeeding

Presenters:

Joseph Ahn, MD, MS, MBA
Professor of Medicine, Section Chief
Division of Gastroenterology and Hepatology
Oregon Health & Science University
Portland, Oregon

Christina Delacruz Leyson, MD
Associate Professor
Medical Director, Liver Transplant Program
Program Director, Hepatology Fellowship
University of Kentucky
Lexington, Kentucky

Alice Chan, person living with chronic hepatitis B

Link to downloadable slides:
https://bit.ly/3rXLTC7

Link to program:
https://bit.ly/3L3Kz6l

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Managing ART Failure: Answering the Questions

support@deceraclinical.com (Daniel R. Kuritzkes MD, Cristina Mussini MD) — Thu, 3 Aug 2023 15:55:52 +0000

In this episode, Daniel R. Kuritzkes, MD, and Cristina Mussini, MD, discuss managing ART failure, including:

The definitions of virologic blips, low-level viremia, and virologic failure on ART
The infrequency of failure with resistance on first-line INSTI-based ART and the instances where this has occurred with BIC- and DTG-based ART in clinical trials and in the real world
The potential reasons for ART failure, including patient/adherence-related factors, HIV-related factors, and regimen-related factors
The impact of adherence on viral suppression with BIC- and DTG-based ART
Drug-drug interactions as a reason for failure of first-line INSTI-based ART
What to do if someone is experiencing virologic failure requiring an ART change
The use of proviral DNA testing in patients with viral suppression or low-level viremia with ART treatment experience
The impact of high HIV-1 RNA on ART effectiveness
The impact of NRTI resistance, including the M184V and K65R mutations, on the effectiveness of BIC- and DTG-based ART
Strategies to encourage and measure patient adherence to ART

Presenters

Daniel R. Kuritzkes, MD
Harriet Ryan Albee Professor of Medicine
Harvard Medical School
Chief, Division of Infectious Diseases
Brigham and Women’s Hospital
Boston, Massachusetts

Cristina Mussini, MD
Professor
Department of Infectious Diseases
University of Modena and
Reggio Emilia
Modena, Italy

Link to full program: https://bit.ly/3HPu4Lk

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Challenging Scenarios: Managing a First ART Failure

support@deceraclinical.com (Renslow Sherer MD) — Wed, 26 Jul 2023 14:03:08 +0000

In this episode, Renslow Sherer, MD, discusses managing a first ART failure in the setting of COVID-19, including:

Guideline recommendations for resistance testing
Guideline recommendations for selecting a new ART regimen
Data on retained efficacy of NRTIs in second-line regimens in the EARNEST and NADIA studies
Consideration of drug‒drug interactions between ART and COVID-19 treatment

Presenter:
Renslow Sherer, MD
Director
International HIV Training Center
Professor of Medicine
Section of Infectious Diseases and Global Health
Department of Medicine
University of Chicago
Chicago, Illinois

To download the slides: https://bit.ly/3OcqxIE

To view the full online program: https://bit.ly/3ZjSFhg

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PrEP Talks: Uptake in Racial and Ethnic Minority Men Who Have Sex With Men and Transgender Individuals

support@deceraclinical.com (Kenyon R. Farrow, Raphael J. Landovitz MD MSc) — Wed, 19 Jul 2023 17:28:31 +0000

In this episode, Kenyon R. Farrow and Raphael J. Landovitz, MD, MSc, discuss key considerations to PrEP uptake in transgender individuals and racial and ethnic minority men who have sex with men, including:

Rates of HIV diagnoses in Black and Brown communities
Issues stalling success in HIV prevention (eg, stigma, healthcare coverage, and administration and operational barriers)
Considerations for healthcare professionals when discussing PrEP with patients
Importance of representation (eg, racial and ethnic minority people, transgender people) at clinic offices
Promoting cultural humility to build strong patient-provider relationships

Faculty:

Kenyon R. Farrow
Vice President of Policy
Point Source Youth
Contributing Editor
TheBody.com
Cleveland, Ohio

Link to full program:
https://bit.ly/3PZGYdR

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PrEP Initiation: Answering the Questions

Thu, 13 Jul 2023 20:28:09 +0000

In this episode, Linda-Gail Bekker, MBChB, DTM&H, DCH, FCP(SA), PhD, and Meredith Clement, MD, discuss PrEP initiation, including:

The importance of taking a sexual history and getting to know your patient
Recommendations for who should be considered for PrEP
Practicalities of PrEP initiation including laboratory assessments, interview and physical exam, evaluating concomitant medications, counseling, and prescribing
Summary of PrEP eligibility by regimen
Review of the clinical trial and real-world data for each PrEP modality
The likelihood of cross-resistance between PrEP options and ART options if someone were to become infected with HIV while receiving PrEP
Time to effective concentrations of PrEP after initiation
Whether there are data for on-demand dosing of FTC/TAF
Recommendations for FTC/TDF on demand for heterosexual cisgender men
Individualizing PrEP for each person to increase the likelihood of adherence, persistence, and efficacy
Recommendations for the use of LA CAB for PrEP during pregnancy and in people of childbearing potential
STI and point-of-care testing for people receiving PrEP
The possibility of implantable PrEP in the future

Presenters:

Linda-Gail Bekker, MBChB, DTM&H, DCH, FCP(SA), PhD
Professor and Director
The Desmond Tutu HIV Centre University of Cape Town
Cape Town, South Africa

Meredith Clement, MD
Assistant Professor
Section of Infectious Diseases
Louisiana State University Health Sciences Center
University Medical Center
New Orleans, Louisiana

Link to full program:
https://bit.ly/3HPu4Lk

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Viral Hepatitis Update: CCO Independent Conference Coverage of EASL 2023

support@deceraclinical.com (Stefan Zeuzem MD) — Tue, 11 Jul 2023 17:33:42 +0000

In this episode, Stefan Zeuzem, MD, discusses new data on viral hepatitis presented at EASL 2023, including:

Hepatitis B virus
- Durability of response with bepirovirsen
- HBsAg loss with siRNA VIR-2218 combined with either VIR-3434 (novel monoclonal antibody) or pegIFN-alfa
Hepatitis delta virus
- 96-week follow-up of immediate vs delayed bulevirtide
- Off-treatment response for lonafarnib + ritonavir ± pegIFN-alfa
- Safety and efficacy outcomes with siRNA JNJ-3989 + nucleos(t)ide analogue
Hepatitis C virus
- Collaborative service at opiate substitution treatment clinic to improve linkage to care in Ireland
- Nurse-led test-and-treat program to increase screening and diagnosis at female prisons in the United Kingdom
- FIND-C study using machine learning to improve screening-to-diagnosis ratio using clinical factors and social determinants of health

Presenter:

Stefan Zeuzem, MD
Professor of Medicine
Chief, Department of Medicine
JW Goethe University Hospital
Frankfurt, Germany

Link to full program:

https://bit.ly/3JQQj3J

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Treatment of Skin and Soft Tissue Infections

support@deceraclinical.com (Kyle Molina PharmD BCIDP) — Tue, 11 Jul 2023 04:00:00 +0000

In this episode, Kyle Molina, PharmD, BCIDP, provides an overview of treatment of skin and soft tissue infections (SSTIs) and challenges in practice. Listen as he gives perspectives on:

Guideline recommendations for treatment of purulent and nonpurulent SSTIs
Logistical challenges with IV and oral antibiotics
Pros and cons of various locations of care
Data supporting the safety and efficacy of long-acting lipoglycopeptides for treatment of SSTIs
Use of long-acting lipoglycopeptides in special populations of interest, including patients with obesity, diabetes, and injection drug use
Overall place in therapy of long-acting lipoglycopeptides for SSTIs

Faculty:

Kyle Molina, PharmD, BCIDP
Infectious Diseases Clinical Pharmacist
Scripps Green Hospital
La Jolla, California

Link to full program:

CCO: https://bit.ly/3J4mg8h
ProCE: https://bit.ly/3P0vB4E

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Answering the Questions on Which HIV PrEP for Which Patient: Latesha Elopre and Jason Farley

Mon, 3 Jul 2023 19:39:18 +0000

In this episode, Latesha Elopre, MD, MSPH, and Jason Farley, PhD, MPH, ANP-BC, FAAN, FAANP, AACRN, answer questions about HIV PrEP including:

How long someone can receive PrEP and the monitoring that is needed over time
Recommendations for monitoring bone health while receiving oral PrEP
Treatment as prevention and PrEP efficacy data and options for people who inject drugs
The role of circumcision in HIV prevention
The use of PrEP in pregnancy
Concern for ART resistance if someone seroconverts while receiving PrEP, especially when using nondaily PrEP options
The possibility of using FTC/TAF on demand
Inequities in adherence and persistence
Cost considerations with different PrEP modalities
Recommendations for hospitalized patients receiving PrEP
PrEP considerations for patients with renal dysfunction and higher BMIs
PrEP efficacy based on site of exposure

Presenters:

Latesha Elopre, MD, MSPH
Associate Professor
Division of Infectious Diseases
Assistant Dean of Diversity and Inclusion
General Medical Education
University of Alabama at Birmingham
Birmingham, Alabama

Jason Farley, PhD, MPH, ANP-BC, FAAN, FAANP, AACRN
Professor
School of Nursing
Johns Hopkins University
Nurse Practitioner
Department of Infectious Diseases
John G. Bartlett Specialty Practice
Baltimore, Maryland

Link to full program:
https://bit.ly/3Fqdgs9

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Q&A on Barriers to HIV PrEP: Pharmacist Perspectives

Tue, 27 Jun 2023 18:18:49 +0000

In this episode, Milena Murray, PharmD, MSc, BCIDP, AAHIVP, FCCP, and Kevin Astle, PharmD, BCPS, BCACP, AAHIVP, CDCES, discuss key considerations to barriers to PrEP uptake, including:

Limited data on “on-demand” PrEP in cisgender women
Strategies on improving communication with non‒English-speaking populations
Role of pharmacists with injectable PrEP
CDC PrEP guideline recommendations on routine HIV-1 RNA testing
Engaging with pregnant persons who might want access to PrEP in the pharmacy setting
Oral PrEP efficacy based on adherence in cisgender women, including recent data presented at CROI 2023 by Marrazzo and colleagues

Presenters:

Milena Murray, PharmD, MSc, BCIDP, AAHIVP, FCCP
Associate Professor
Department of Pharmacy Practice
Midwestern University College of Pharmacy, Downers Grove Campus
Downers Grove, Illinois
System-Level HIV/ID Clinical Pharmacist
Ambulatory Pharmacy
Northwestern Medicine
Wheaton, Illinois

Kevin Astle, PharmD, BCPS, BCACP, AAHIVP, CDCES
Assistant Professor
Department of Pharmacotherapy and Clinical Research
University of South Florida
Clinical Pharmacist
Tampa General Medical Group
Tampa, Florida

Content based on an online CME program supported by an independent educational grant from ViiV Healthcare.

Link to full program:
https://bit.ly/3ZjSFhg

Downloadable slides:
https://bit.ly/3PsFNDt

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Older Adults: Overcoming HBV Barriers

support@deceraclinical.com (Robert S. Brown Jr. MD MPH, Nancy Reau MD) — Fri, 23 Jun 2023 16:25:03 +0000

In this episode, Robert S. Brown, Jr., MD, MPH; Nancy Reau, MD; and Eric, a person living with chronic hepatitis B, discuss solutions for overcoming barriers to HBV care in older adults, including:

Awareness of HBV and CHB in older adults
Updated HBV screening and vaccination recommendations
Monitoring of renal and bone disease
Adjustment of monitoring and treatment as a person with HBV ages

Presenters:
Robert S. Brown, Jr., MD, MPH
Vincent Astor Distinguished
Professor of Medicine
Chief, Division of Gastroenterology and Hepatology
Weill Cornell Medicine
New York, New York

Nancy Reau, MD
Professor of Medicine
Chief, Section of Hepatology
Associate Director, Solid Organ Transplantation
Richard B. Capps Chair of Hepatology
Rush University Medical Center
Chicago, Illinois

Eric, person living with chronic hepatitis B

Link to downloadable slides: please link to VM404 downloadable slides when ready

Link to program:
bit.ly/3L3Kz6l

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Hepatitis Delta in Focus: Episode 4 of Answering the Questions on Screening, Diagnosis, and Treatment

support@deceraclinical.com (Tarik Asselah MD PhD, Ira Jacobson MD) — Thu, 22 Jun 2023 14:00:13 +0000

In this episode, Tarik Asselah, MD, PhD, and Ira Jacobson, MD, provide expert insight on HDV screening, diagnosis, and management, including:

Approach to screening
Barriers to screening (eg, test availability)
Disease progression and complications
Differentiating between coinfection and superinfection
Approach to treatment (eg, whom to treat and when, treatment options, considerations for combination therapy)
Management of patients with decompensated cirrhosis
Surrogate markers to measure treatment success
Role of correcting thrombocytopenia before initiating therapy

Faculty:

Tarik Asselah, MD, PhD
Professor of Medicine
Department of Hepatology
Hôpital Beaujon
Université de Paris
Clichy, France

Ira Jacobson, MD
Professor of Medicine
NYU School of Medicine
Director of Hepatology
Division of Gastroenterology and Hepatology
NYU Langone Health
New York, New York

Link to full program: https://bit.ly/3yp1Lxf

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Preparing for the Fall: New RSV Vaccine Approvals

support@deceraclinical.com (Helen Y Chu MD MPH) — Mon, 19 Jun 2023 18:45:39 +0000

In this episode, Helen Y. Chu, MD, MPH, shares updates on RSV vaccines, including:

An overview of vaccine candidates under investigation
Recently FDA-approved RSV vaccines for older adults
Considerations for the next respiratory viral season
Coadministration of RSV vaccines with other respiratory viral vaccines (eg, influenza, SARS-CoV-2)
Target populations for RSV vaccination
RSV prevention in infants with the maternal vaccine and monoclonal

Faculty:

Helen Y. Chu, MD, MPH
Associate Professor of Medicine
Division of Allergy & Infectious Diseases
University of Washington
School of Medicine
Seattle, Washington

Link to full program: https://bit.ly/3nb25xehttps://bit.ly/3nb25xe

Link to downloadable slides: https://bit.ly/3TsXym5

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Hepatitis Delta in Focus: Episode 3 of Answering the Questions on Screening, Diagnosis, and Treatment

support@deceraclinical.com (Nancy Reau MD, Heiner Wedemeyer MD) — Mon, 19 Jun 2023 18:38:34 +0000

In this episode, Nancy Reau, MD, and Heiner Wedemeyer, MD, provide expert insight on HDV management, including:

Use of noninvasive imaging or biopsy for staging liver disease
Screening for hepatocellular carcinoma
HBV treatment
Role of comedications (eg, erythropoietin, eltrombopag)
Approach to complex cases, such as patients with:
- Significant fibrosis and low HDV RNA levels
- Hepatitis delta antibody positivity, but HDV RNA negativity
- HIV coinfection
- Decompensated or recently decompensated cirrhosis

Faculty:

Heiner Wedemeyer, MD
Professor and Chairman
Department of Gastroenterology, Hepatology and Endocrinology
Hannover Medical School
Hannover, Germany

Link to full program:
http://bit.ly/3yp1Lxf

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Modifying ART in the Presence of Hyperlipidemia: Using HIV-ASSIST

support@deceraclinical.com (Maunank Shah MD PhD) — Fri, 9 Jun 2023 04:00:00 +0000

In this episode, Maunank Shah, MD, PhD, discusses using HIV-ASSIST to optimize treatment for both HIV and hyperlipidemia. Listen as he covers:

Hyperlipidemia and cardiovascular disease risk among people living with HIV
Recommendations for lipid screening for people living with HIV
Using HIV-ASSIST to support ART treatment decisions for people living with HIV with comorbidities
How HIV-ASSIST prioritizes certain ART agents in the setting of hyperlipidemia, including:
- Deciding between bictegravir, doravirine, dolutegravir, raltegravir, and rilpivirine vs boosted protease inhibitors, including darunavir
- Deciding between tenofovir disoproxil fumarate and tenofovir alafenamide or abacavir
How HIV-ASSIST incorporates drug‒drug interaction data from the University of Liverpool HIV Drug Interactions Checker and the DHHS guidelines when considering the use of statin therapy with ART
How HIV-ASSIST further incorporates drug resistance data from the Stanford HIV Drug Resistance Database

Maunank Shah, MD, PhD
Associate Professor
Infectious Diseases
Johns Hopkins University
Baltimore, Maryland

Link to full program: bit.ly/3pwaH2Y

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The Burden of Skin and Soft Tissue Infections: Epidemiology, Clinical Presentation, and Diagnosis

support@deceraclinical.com (Martin Krsak MD MSc FASAM) — Thu, 8 Jun 2023 11:41:20 +0000

In this episode, Martin Krsak, MD, MSc, FASAM, provides background and context on skin and soft tissue infections. Listen as he gives perspectives on:

Epidemiology and clinical outcomes
Economic impact
Bacterial etiology
Importance of appropriate antimicrobial prescribing
Clinical presentation
Severity classification and distinction between purulent and nonpurulent infections
Role of incision and debridement vs antimicrobial management
Complications to be ruled out prior to treatment

Faculty:
Martin Krsak, MD, MSc, FASAM
Associate Professor of Medicine
Division of Infectious Diseases
University of Colorado School of Medicine
Denver, Colorado

Link to full program:

CCO: https://bit.ly/3J4mg8h
ProCE: https://bit.ly/3P0vB4E

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Choosing Between Initial ART Options: Answering the Questions

support@deceraclinical.com (Michelle Cespedes MD MS, Marta Boffito MD PhD FRCP) — Tue, 6 Jun 2023 10:40:37 +0000

In this episode, Marta Boffito, MD, PhD, FRCP, and Michelle Cespedes, MD, MS, discuss initial ART options, including:

Recommended first-line ART options for most PWH according to DHHS, IAS-USA, EACS, BHIVA, and WHO guidelines
Data for weight gain after ART initiation with different ARV classes and drugs
Weight gain disparities by race and gender after ART initiation
Data from the RESPOND study including risk factors for weight gain and CV event risk with INSTI vs non-INSTI–based ART
The impact of INSTIs on CV events in the Swiss HIV Cohort study
Recommendations for ART and contraception for PWH of childbearing potential
Drug–drug interactions between first-line ART and contraceptive options
Guideline-recommended first-line ART options in pregnancy with a discussion of how these regimens differ from those recommended for most PWH

Marta Boffito, MD, PhD, FRCP
Consultant Physician
Clinical Director, HIV, Sexual and Gender Health, Dermatology
Chelsea and Westminster Hospital NHS Foundation Trust
Imperial College London
London, United Kingdom

Michelle Cespedes, MD, MS
Professor of Medicine
Division of Infectious Disease
Department of Medicine
Icahn School of Medicine at
Mount Sinai
New York, New York

Link to full program: bit.ly/3HPu4Lk

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Choosing ART for HIV With HBV and HCV Coinfections: Using HIV-ASSIST

support@deceraclinical.com (Carolyn Chu) — Tue, 30 May 2023 12:09:32 +0000

In this episode, Carolyn Chu, MD, MSc, FAAFP, AAHIVS, discusses using HIV-ASSIST to aid in the selection of an ART regimen for PWH coinfected with HBV and HCV. Listen as she covers:

How HIV-ASSIST supports ART selection in primary care
Updates to viral hepatitis recommendations including:
CDC HBV screening and testing recommendations
AASLD simplified HCV treatment approach for PWH
HIV-ASSIST for managing HIV/HBV coinfections, including ensuring that NRTIs that are effective for both HIV and HBV are included in an ART regimen and alerting the user when an additional HBV treatment is needed
HIV-ASSIST for managing HIV/HCV coinfections, including showing how the HIV-ASSIST tool incorporates drug‒drug interaction considerations from the University of Liverpool HIV Drug Interaction Checker

Carolyn Chu, MD, MSc, FAAFP, AAHIVS
Chief Clinical Officer
National Clinician Consultation Center
Professor
Clinical Family Community Medicine
University of California, San Francisco
San Francisco, California

Link to full program: bit.ly/3pwaH2Y

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Integrating New Data on LA ART From CROI 2023: Pharmacist Perspectives

Mon, 22 May 2023 19:28:29 +0000

In this episode, Amanda Binkley, PharmD, BCIDP, AAHIVP, and Nimish Patel, PharmD, PhD, AAHIVP, discuss clinically relevant data on long-acting ART from CROI 2023, including:

LA CAB + RPV in San Francisco’s Ward 86 Safety Net Clinic Serving Publicly Insured PWH
SOLAR: Randomized Switch to LA CAB + RPV From BIC/FTC/TAF

Amanda Binkley, PharmD, BCIDP, AAHIVP
Clinical Pharmacy Specialist
Infectious Disease
Department of Pharmacy
Penn Presbyterian Medical Center
Philadelphia, Pennsylvania

Nimish Patel, PharmD, PhD, AAHIVP
Professor
Department of Clinical Pharmacy
Skaggs School of Pharmacy & Pharmaceutical Sciences
University of California
La Jolla, California

Link to full program: bit.ly/3ZjSFhg

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Christine Katlama and Babafemi Taiwo: Answering the Questions on Optimizing Antiretroviral Therapy in Heavily Treatment–Experienced People With HIV

support@deceraclinical.com (Christine Katlama MD, Babafemi Taiwo MBBS) — Tue, 16 May 2023 14:14:31 +0000

In this episode, Christine Katlama, MD, and Babafemi Taiwo, MBBS, discuss optimizing ART for people with HIV who are treatment experienced or failing a current ART regimen, including:

Recycling agents from the NRTI, NNRTI, INSTI, and PI classes in salvage ART regimens
Maintaining NRTIs in second-line and salvage ART regimens, including the use of 3TC, TFV, and ABC
ART regimen simplification
When to perform genotypic resistance testing, including for PWH who have been off ART
When to perform DNA genotyping for archived resistance testing
Considering LA CAB + RPV with prior NNRTI exposure, ART resistance, or past adherence concerns with oral ART
Using boosted DRV + DTG in salvage regimens
Switching from boosted PIs to INSTIs in PWH receiving second-line therapy
Second-line regimens with LA CAB + RPV failure

Christine Katlama, MD
Professor
Sorbonne University APHP Paris
Head, HIV/Hepatitis Clinical and Research Unit
Department of Infectious Diseases
Paris, France

Babafemi Taiwo, MBBS
Gene Stollerman Professor of Medicine
Chief, Division of Infectious Diseases
Northwestern University Feinberg School of Medicine
Chicago, Illinois

Link to full program: https://bit.ly/3Z44Gq3

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Preconception ART Selection: Using HIV-ASSIST

support@deceraclinical.com (Sonya Krishnan MD MHS) — Thu, 11 May 2023 12:36:47 +0000

In this episode, Sonya Krishnan, MD, MHS, discusses using HIV-ASSIST to aid in the selection of an ART regimen for a virologically suppressed PWH who is planning a pregnancy. Listen as she covers:

How to input patient specific factors into the HIV-ASSIST tool
Discussion of available education sheets to review the data and recommendations for her current ART regimen in pregnancy
An explanation of why some regimens are ranked lower because of adherence factors such as increased pill burden or dosing frequency
Guidelines informing the HIV-ASSIST output, including DHHS and IAS-USA, and the frequency with which updates are incorporated
How to use the HIV-ASSIST output to guide regimen selection in pregnancy
Use of the HIV-ASSIST tool in shared decision-making and patient counseling

Sonya Krishnan, MD, MHS
Assistant Professor
Division of Infectious Diseases
Johns Hopkins University
Baltimore, Maryland

Link to full program:
bit.ly/3pwaH2Y

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Long-Acting ART: Cabotegravir Plus Rilpivirine

support@deceraclinical.com (Ian Frank MD) — Wed, 10 May 2023 13:39:34 +0000

In this episode, Ian Frank, MD, discusses long-acting HIV treatment with cabotegravir plus rilpivirine for people with HIV, including:

Efficacy data with every-8-week dosing
Real-world use in people with viremia
Initiation and continuation strategies
Virologic failure data
Safety information

Presenter:

Ian Frank, MD

Associate Chief

Division of Infectious Diseases

Professor of Medicine

University of Pennsylvania

Philadelphia, Pennsylvania

To download the slides: https://bit.ly/3HX1GGn

To view the full online program: https://bit.ly/3ZjSFhg

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COVID-19 Update: Independent Conference Coverage of ECCMID 2023

support@deceraclinical.com (Patrick W. G. Mallon MB BCh PhD FRACP FRCPI) — Fri, 5 May 2023 20:14:47 +0000

In this episode, Patrick W. G. Mallon, MB, BCh, PhD, FRACP, FRCPI, discusses new data on COVID-19 presented at ECCMID 2023, including:

Treatment in special populations
- REDPINE: remdesivir in people with renal impairment hospitalized for COVID-19 pneumonia
- Remdesivir and readmission for COVID-19 in immunocompromised patients
- Molnupiravir vs nirmatrelvir plus ritonavir for COVID-19 with hematologic malignancy
Management of patients with severe disease
- RECOVERY: higher-dose vs standard-dose corticosteroids for hospitalized patients with COVID-19
- Real-world study of tocilizumab vs baricitinib for severe COVID-19
Novel antivirals
- Ensitrelvir
- Bemnifosbuvir
Novel vaccines
- NB2155
- AZD2816/AZD1222
- qNIV/CoV2373
- GRT-R910
- NVX-CoV2373 in people with HIV

Faculty:
Patrick W. G. Mallon, MB, BCh, PhD, FRACP, FRCPI
Professor of Microbial Diseases
Centre for Experimental Pathogen Host Research
University College Dublin
Dublin, Ireland

Content based on an online CME/CE program supported by independent educational grants from Gilead Sciences, Inc. and Novavax.

Link to full program:
bit.ly/3niXGJ6

Link to downloadable slides:
bit.ly/3LUFejG

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2023 Audio Recap: Principles of Outpatient COVID-19 Management

support@deceraclinical.com (Renslow Sherer MD, Trinh P. Vu PharmD BCIDP) — Wed, 3 May 2023 15:51:04 +0000

In this episode, Renslow Sherer, MD, and Trinh P. Vu, PharmD, BCIDP, discuss strategies for managing ambulatory patients with acute or previous COVID-19 infection, including:

Current COVID-19 landscape
Rapid antigen tests and PCR tests
Risk stratification of patients who have a positive SARS-CoV-2 test
Antiviral treatment (nirmatrelvir + ritonavir, remdesivir, and molnupiravir)
Long COVID

Presenters:
Renslow Sherer, MD
Director, International HIV Training Center
Professor of Medicine
Section of Infectious Diseases and Global Health
Department of Medicine
University of Chicago
Chicago, Illinois

Trinh P. Vu, PharmD, BCIDP
Clinical Pharmacy Specialist in Infectious Diseases
Department of Pharmaceutical Services
Emory University Hospital Midtown
Atlanta, Georgia

To download the slides: bit.ly/3oHKC09

To view the full online program: bit.ly/4201xcO

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Complicated Clinical Infections: Clinical Impact of New Data From ECCMID 2023

support@deceraclinical.com (David van Duin MD PhD FIDSA FAST) — Wed, 3 May 2023 11:41:27 +0000

In this episode, David van Duin, MD, PhD, FIDSA, FAST, discusses new data on complicated clinical infections presented at ECCMID 2023, including:

Gram-negative resistance
- Pharmacokinetic and clinical outcomes in patients receiving meropenem/vaborbactam for KPC-producing carbapenem-resistant Enterobacterales infections
- Comparative study of cefiderocol- vs colistin-containing regimens for CRAB VAP with concomitant bacteremia
- Real-world use of imipenem/cilastatin/relebactam for the treatment of infections caused by multidrug-resistant organisms
Antimicrobial stewardship
- Safety and efficacy of antibiotic de-escalation from an antipseudomonal β-lactam in patients with Enterobacterales BSIs in SIMPLIFY
- The SOAB study comparing clinical outcomes of switching to oral antibiotics after IV lead-in therapy vs continuing IV therapy in patients with Enterobacterales BSIs
- Data from REGARD-VAP on outcomes of shortened antibiotic treatment for VAP guided by clinical criteria
Investigational agents
- Open-label study following ATTACK of patients with colistin-resistant CRAB infections receiving sulbactam/durlobactam
- Summary of findings from EAGLE-2 and EAGLE-3 of gepotidacin for uncomplicated UTI treatment
- Post hoc DOOR analysis of SURE-2 of sulopenem for the treatment of complicated UTIs

Faculty:
David van Duin, MD, PhD, FIDSA, FAST
Professor of Medicine
Director, Immunocompromised Host Infecious Diseases Program
Division of Infectious Diseases
University of North Carolina
Chapel Hill, North Carolina

Content based on an online CME/CE program supported by an independent educational grant from Shionogi Inc.

Link to full program: https://bit.ly/3niXGJ6

Link to downloadable slides: https://bit.ly/3Hx0ppn

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2023 Audio Recap: Practical Case Studies in Outpatient COVID-19 Management

support@deceraclinical.com (Tracey Piparo PA-C, Renslow Sherer MD) — Tue, 2 May 2023 11:46:47 +0000

In this episode, Tracey Piparo, PA-C, and Renslow Sherer, MD, discuss cases of nonhospitalized patients with COVID-19, including:

Young, healthy patient with no risk factors
Young, healthy patient with risk factors
Older patient with immunocompromise
Older patient with renal dysfunction
Patient experiencing hypoxia

Presenters:

Tracey Piparo, PA-C
Department of Palliative Medicine
RJWBarnabas
New Brunswick, New Jersey

Renslow Sherer, MD
Director, International HIV Training Center
Professor of Medicine
Section of Infectious Diseases and Global Health
Department of Medicine
University of Chicago
Chicago, Illinois

To download the slides: bit.ly/44cgH0q

To view the full online program: https://bit.ly/4201xcO

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Q&A: HDV Management Episode 2

support@deceraclinical.com (Tatyana Kushner MD MSCE, Stefan Zeuzem MD) — Wed, 26 Apr 2023 21:00:00 +0000

In this episode, Tatyana Kushner, MD, MSCE, and Stefan Zeuzem, MD, address key considerations when screening, diagnosing, and treating patients with HDV, such as:

Barriers to HDV screening, including limitations to AASLD guideline recommendations
Use of double reflex testing to improve HDV diagnosis
Considerations for repeat HDV testing in patients who are HBsAg positive who previously tested negative for HDV
Updated CDC recommendations for HBV screening for all adults using a triple panel test
Staging advanced liver disease in patients with HDV
Indications for HDV treatment, including patients with low ALT levels and advanced or progressive liver disease
Treatment landscape for HDV
Personal experiences with use of pegylated interferon for HDV treatment, including considerations for use in patients with compensated cirrhosis
Updates on novel HDV therapies, including:
- Summary of efficacy data on bulevirtide from clinical trials
- Interpretation of results from D-LIVR, a phase III trial assessing the safety and efficacy of lonafarnib

Link to full program:
bit.ly/3yp1Lxf

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Overcoming HBV Barriers: Focus on Asian American People

Tue, 25 Apr 2023 12:09:04 +0000

In this episode, Joseph Lim, MD; Mindie H. Nguyen, MD, MAS, AGAF, FAASLD; and Jennifer Wild, MS, BSN, RN, OCN, discuss strategies for overcoming barriers to HBV care in Asian American people, including:

HBV-related stigma
Language barriers
Health insurance navigation

Presenters:

Joseph Lim, MD
Professor of Medicine
Director, Clinical Hepatology
Vice-Chief, Section of Digestive Diseases
Yale University School of Medicine
New Haven, Connecticut

Mindie H. Nguyen, MD, MAS, AGAF, FAASLD
Professor of Medicine (GI & Hepatology, Liver Transplant)
Professor of Epidemiology & Population Health (By Courtesy)
Director of Hepatology Fellowship
Director of Hepatology Clerkship
Stanford University Medical Center
Palo Alto, California

Jennifer Wild, MS, BSN, RN, OCN
Clinical Nurse
UCSF Helen Diller Family Comprehensive Cancer Center
GI Medical Oncology, Outpatient Hepatobiliary Program
Oakland, California

Link to downloadable slides: please link to VM401 downloadable slides when ready

Link to program: please link to HEP 2023 HBV Key Communities VM (PRP5676) when ready

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African Immigrant People: Overcoming HBV Barriers

support@deceraclinical.com (Essa Mohamed, Daouda Ndiaye, Ponni Perumalswami) — Tue, 25 Apr 2023 11:57:40 +0000

In this episode, Essa Mohamed, PhD; Daouda Ndiaye; and Ponni Perumalswami, MD, MS, discuss strategies for overcoming barriers to HBV care in African immigrant people, including:

HBV awareness and misconceptions
HBV-related stigma
Language barriers
Health insurance navigation

Presenters:
Essa Mohamed, PhD
Clinical Researcher
Division of Gastroenterology and Hepatology
Mayo Clinic
Rochester, Minnesota

Daouda Ndiaye
Patient Navigator

Ponni Perumalswami, MD, MS
Associate Professor of Internal Medicine
Division of Gastroenterology and Hepatology
University of Michigan
Ann Arbor, Michigan

Link to program: bit.ly/3L3Kz6l

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Individualizing HIV ART: Considerations for Weight Gain

support@deceraclinical.com (Daniel R. Kuritzkes MD) — Mon, 24 Apr 2023 12:30:44 +0000

In this episode, Daniel R. Kuritzkes, MD, discusses considerations for patients experiencing weight gain on antiretroviral therapy, including:

• Commonly implicated antiretroviral therapy regimens and patient populations

• Guideline recommendations for management of weight gain

Presenter:

Daniel R. Kuritzkes, MD
Harriet Ryan Albee Professor of Medicine
Harvard Medical School
Chief, Division of Infectious Diseases
Brigham and Women’s Hospital
Boston, Massachusetts

To download the slides:
bit.ly/3odUA9C

To view the full online program:
bit.ly/3ZjSFhg

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Rapid ART Initiation: Answering the Questions

support@deceraclinical.com (Isolde Butler MD, Brenda E. Crabtree Ramírez MD) — Fri, 21 Apr 2023 04:00:00 +0000

In this episode, Isolde Butler, MD, and Brenda E. Crabtree Ramírez, MD, discuss rapid ART initiation for people newly diagnosed with HIV, including:

The HIV care continuum in the United States and Latin America
Barriers to HIV diagnosis, including stigma, discriminatory laws and policies, social determinants of health, and lack of access to healthcare
Factors that predict delayed care linkage and inconsistent HIV care and treatment
Improved clinical outcomes that have been shown with rapid ART initiation, first in low- and middle-income countries and now worldwide
Recommendations for rapid ART—and regimen choices—from the DHHS, IAS-USA, CENSIDA, EACS, and WHO
Recommendations for transitioning from PrEP to ART when someone seroconverts while receiving either oral PrEP or LA CAB for PrEP
Barriers to rapid ART initiation in their individual care settings
The future of LA injectable ART for initial treatment and rapid initiation

Isolde Butler, MD
Chief Medical Officer
CrescentCare
New Orleans, Louisiana

Brenda E. Crabtree Ramírez, MD
Assistant Professor, HIV Program
Department of Infectious Diseases
Instituto Nacional de Ciencias Médicas y Nutrición, Salvador Zubirán
Mexico City, Mexico

Link to full program: bit.ly/3HPu4Lk

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Individualizing HIV ART: Rapid Start

support@deceraclinical.com (Daniel R. Kuritzkes MD) — Thu, 13 Apr 2023 17:11:49 +0000

In this episode, Daniel R. Kuritzkes, MD, discusses considerations for rapid initiation of antiretroviral therapy in patients who are newly diagnosed with HIV, including:

Recommended regimens
Management of patients previously receiving PrEP
Timing of laboratory testing

Presenter:

Daniel R. Kuritzkes, MD
Harriet Ryan Albee Professor of Medicine
Harvard Medical School
Chief, Division of Infectious Diseases
Brigham and Women’s Hospital
Boston, Massachusetts

To download the slides:
https://bit.ly/3odUA9C

To view the full online program:
https://bit.ly/3ZjSFhg

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Perspectives From Asia on Advances in HIV Treatment and Prevention

Mon, 27 Mar 2023 17:23:40 +0000

In this episode, 2 HIV experts from the Asia-Pacific region share their thoughts on some of the most important new insights from HIV treatment and prevention research over the past year.

Specifically, the faculty discuss the role of newer innovations in HIV, including 2-drug oral antiretroviral therapy (ART) regimens, 2-drug long-acting injectable ART, and long-acting HIV pre-exposure prophylaxis in HIV care in the Asia-Pacific region, as well as the implications of weight gain with ART and important considerations related to the unique challenges associated with caring for the aging population of people with HIV in the region.

Presenters:

Anchalee Avihingsanon, MD, PhD
HIV-NAT, Thai Red Cross AIDS Research Centre
Pathumwan, Bangkok, Thailand
Senior Clinical Trial
Medicine
Bangkok, Thailand

Reena Rajasuriar, BPharm, MPharm, PhD
Associate Professor
Department of Medicine
University of Malaya
Kuala Lumpur, Malaysia

Content based on an online program supported by an independent educational grant from Gilead Sciences, Inc. andViiV Healthcare.

Link to full program:
bit.ly/3Hz0jNa

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RSV in Adults: How It Presents

support@deceraclinical.com (Angela Branche, Helen Y. Chu) — Wed, 22 Mar 2023 14:00:00 +0000

In this episode, Angela Branche, MD, and Helen Y. Chu, MD, MPH, discuss the clinical presentation of respiratory syncytial virus (RSV) in adults and the importance of early detection, including:

Clinical symptoms and presentation
Complications, including exacerbations of cardiopulmonary diseases
Use of medical resources compared with other respiratory viruses
Diagnostic approaches and challenges
Treatment and management of RSV disease
Clinical impact of RSV awareness

Faculty:

Angela Branche, MD

Associate Professor of Medicine
Division of Infectious Diseases
Department of Medicine
University of Rochester
Rochester, New York

Helen Y. Chu, MD, MPH
Associate Professor of Medicine
Division of Allergy & Infectious Diseases
University of Washington
School of Medicine
Seattle, Washington

Link to full program:
bit.ly/3nb25xe

Link to downloadable slides:
bit.ly/3TsXym5

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RSV in Adults: A Hidden Epidemic

support@deceraclinical.com (Angela Branche, Helen Y. Chu) — Wed, 22 Mar 2023 13:45:00 +0000

In this episode, Angela Branche, MD, and Helen Y. Chu, MD, MPH, discuss the impact of respiratory syncytial virus (RSV) and describe those at risk for severe RSV disease, including:

RSV prevalence and seasonality
RSV burden throughout life, including burden in older adults
Comorbidities that increase the risk of RSV complications
RSV transmission in the hospital and care home setting
Implications of risk factors for severe RSV on prevention and treatment

Faculty:

Angela Branche, MD
Associate Professor of Medicine
Division of Infectious Diseases
Department of Medicine
University of Rochester
Rochester, New York

Helen Y. Chu, MD, MPH
Associate Professor of Medicine
Division of Allergy & Infectious Diseases
University of Washington
School of Medicine
Seattle, Washington

Link to full program:
bit.ly/3nb25xe

Link to downloadable slides:
bit.ly/3TsXym5

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Answering the Questions on Optimizing Antiretroviral Therapy in Heavily Treatment–Experienced People With HIV: José R. Arribas and Melissa Badowski

Tue, 21 Mar 2023 23:40:00 +0000

In this episode, José R. Arribas, MD, and Melissa Badowski, PharmD, MPH, FIDSA, FCCP, BCIDP, BCPS, AAHIVP, discuss optimizing antiretroviral therapy (ART) for people with HIV who are treatment experienced or failing a current ART regimen, including:

The use of proviral DNA genotyping for switching therapy
Maintaining nucleos(t)ide reverse-transcriptase inhibitors after a first failure
The role of zidovudine in salvage regimens
The use of twice-daily darunavir with protease inhibitor resistance and twice-daily dolutegravir with integrase strand transfer inhibitor resistance
Simplification of regimens and long-acting therapies for people with HIV who are highly treatment experienced
Drug‒drug interactions that may warrant dosing changes to avoid resistance development
When to consider antiretrovirals with novel mechanisms of action, such as fostemsavir, ibalizumab, and lenacapavir
The logistics of dosing, administration, and development of a complete ART regimen that includes novel mechanism antiretrovirals
Addressing psychosocial factors to increase the chance of success on a new ART regimen
Drug‒drug interactions with novel mechanism agents
How common ART resistance is for people with HIV in their own practices
The possibility of using long-acting cabotegravir plus rilpivirine in people with viremia in the future
Addressing low-level viremia

José R. Arribas, MD
Professor of Medicine
Department of Medicine
Autónoma University School of Medicine
Head, Infectious Diseases Unit
Department of Internal Medicine
Hospital La Paz
Madrid, Spain

Melissa Badowski, PharmD, MPH, FIDSA, FCCP, BCIDP, BCPS, AAHIVP
Clinical Associate Professor
Section of Infectious Diseases Pharmacotherapy
Department of Pharmacy Practice
University of Illinois at Chicago, College of Pharmacy
Chicago, Illinois

Link to full program:
bit.ly/3Z44Gq3

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Answering the Questions on HIV PrEP Persistence

support@deceraclinical.com (Decera Clinical Education) — Thu, 16 Mar 2023 20:20:00 +0000

In this episode, Darrell H. S. Tan, MD, FRCPC, PhD, and Kenric Ware, PharmD, AAHIVP, discuss considerations for HIV pre-exposure prophylaxis (PrEP) persistence, including:

The PrEP continuum of care in the United States, including inequities in PrEP uptake and persistence by race
CDC PrEP guidance regarding PrEP indications
PrEP eligibility by regimen
Summary of renal, bone, and weight outcomes with different PrEP options
Data on HIV acquisition following PrEP discontinuation
Drug concentrations and recommendations for stopping long-acting cabotegravir for PrEP
Expanding PrEP options to facilitate adherence and persistence
Providing PrEP by telehealth

Presenters:

Darrell H. S. Tan, MD, FRCPC, PhD
Associate Professor
Division of Infectious Diseases
University of Toronto
Clinician-Scientist
Division of Infectious Diseases
St. Michael’s Hospital
Toronto, Canada

Kenric Ware, PharmD, AAHIVP
Associate Professor
Department of Pharmacy Practice
South University
Savannah, Georgia
Chairperson, Pharmacist
Board of Directors
Joseph H. Neal Health Collaborative
Columbia, South Carolina

Link to full program:
https://bit.ly/3HPu4Lk

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Answering Questions on Which HIV PrEP for Which Patient: Carolyn Chu and Samantha Strong

Wed, 15 Mar 2023 20:30:00 +0000

In this episode, Carolyn Chu, MD, MSc, FAAFP, AAHIVS, and Samantha Strong, PharmD, BCACP, AAHIVP, CDCES, answer questions including:

Strategies to improve disparities in pre-exposure prophylaxis (PrEP) access in difficult-to-reach populations
Key remaining questions related to PrEP options for cisgender women and people who inject drugs
Concerns about resistance at seroconversion in patients with suboptimal PrEP compliance
Implementation of molecular screening for patients receiving PrEP
Expectations for weight gain and patient counseling points

Presenters:

Carolyn Chu, MD, MSc, FAAFP, AAHIVS
Chief Medical Officer
American Academy of HIV Medicine
Chief Clinical Officer
National Clinician Consultation Center

Samantha Strong, PharmD, BCACP, AAHIVP, CDCES
Clinical Director of Pharmacy
Nevada Health Centers
Las Vegas, Nevada

Link to full program:
https://bit.ly/3Fqdgs9

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Hepatitis Delta in Focus: Episode 1 of Answering the Questions on Screening, Diagnosis, and Treatment

support@deceraclinical.com (Maria Buti MD, Richard H Davis PA-C) — Wed, 8 Mar 2023 21:25:00 +0000

In this episode, Maria Buti, MD, and Richard H. Davis, PA-C, address key considerations when screening, diagnosing, and treating patients with hepatitis delta virus (HDV), such as:

Barriers to screening
HDV screening based on patient risk factors
Universal screening for all patients with positive hepatitis B surface antigen (HBsAg)
Reflex testing
Availability of commercial testing
Monitoring suggestions in HBsAg positive and HDV antibody positive patients with negative HDV RNA
Limitations to evaluating advanced fibrosis in patients with HDV
Data on novel HDV therapies (eg, bulevirtide and lonafarnib)
Extending HDV therapy (eg, peginterferon) based on treatment response
Stopping rules (eg, HDV RNA negativity, HBsAg loss) for discontinuing HDV therapy

Faculty:

Maria Buti, MD
Professor of Medicine
Hospital Universitario Vall d’Hebron
Barcelona, Spain

Richard H. Davis, PA-C
Senior PA
Gastroenterology
University of Florida
UF Health
Gainesville, Florida

Link to full program:
http://bit.ly/3yp1Lxf

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Barriers to HIV PrEP: Addressing Intersectionality

support@deceraclinical.com (Latesha Elopre MD MSPH) — Mon, 6 Mar 2023 21:30:00 +0000

In this episode, Latesha Elopre, MD, MSPH, discusses key considerations to barriers to PrEP uptake, including:

Addressing disparities among racial and ethnic minority populations
Understanding the concept of intersectionality
Tackling multiple levels of intersectionality
Individual (eg, self-stigma, mental health)
Network (eg, access to PrEP services)
Community (eg, racism, stigma, poverty)
Social and structural (eg, laws/policies)
Epidemic (eg, population level of viremia)

Presenter:

Content based on an online CME program supported by an independent educational grant from ViiV Healthcare.

Link to full program:
https://bit.ly/3ZjSFhg

Follow along with the slides:
https://bit.ly/3YmeRWy

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Long-Acting ART: Lenacapavir

support@deceraclinical.com (Darcy Wooten MD) — Fri, 3 Mar 2023 21:30:00 +0000

In this episode, Darcey Wooten, MD, discusses the long-acting HIV treatment agent lenacapavir for treatment-experienced people with HIV, including:

Efficacy data
Initiation strategies
Virologic failure data
Safety information

Presenter:

Darcy Wooten, MD
Associate Professor of Medicine
Division of Infectious Diseases and Global Public Health
Department of Medicine
University of California, San Diego
San Diego, California

To download the slides:
http://bit.ly/3Jb1ofX

To view the full online program:
https://bit.ly/3ZjSFhg

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Long-Acting PrEP: Monitoring for New HIV Infection

support@deceraclinical.com (Darcy Wooten MD) — Fri, 3 Mar 2023 21:30:00 +0000

In this episode, Darcey Wooten, MD, discusses updated guidance and rationale for monitoring for new HIV infections in people receiving long-acting PrEP, including:

Testing both Ag/Ab and HIV-1 RNA
Steps to take when a person receiving long-acting PrEP develops a new HIV infection

Presenter:

Darcy Wooten, MD
Associate Professor of Medicine
Division of Infectious Diseases and Global Public Health
Department of Medicine
University of California, San Diego
San Diego, California

To download the slides:
https://bit.ly/3Jb1ofX

To view the full online program:
https://bit.ly/3ZjSFhg

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Ensuring Linkage to Care for Patients Diagnosed With Hepatitis Delta Virus

support@deceraclinical.com (Nancy Reau MD, Lydia Tang MBChB) — Thu, 23 Feb 2023 21:35:00 +0000

In this episode, Nancy Reau, MD, and Lydia Tang, MBChB, discuss how to increase linkage to care rates for persons with hepatitis D virus, including:

Updates on currently low rates of linkage to care
Barriers preventing patients with HBV/HDV
coinfection from engaging in care
Interventions to increase retention in care for patients with HDV

Faculty:
Nancy Reau, MD
Professor of Medicine
Chief, Section of Hepatology
Associate Director, Solid Organ Transplantation
Richard B. Capps Chair of Hepatology
Rush University Medical Center
Chicago, Illinois

Lydia Tang, MBChB
Assistant Professor
Department of Infectious Diseases
University of Maryland School of Medicine
Institute of Human Virology
Baltimore, Maryland

Link to full program:
https://bit.ly/41oYawr

Follow along with the slides at:
https://bit.ly/3XW6m4g

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How to Screen for Hepatitis Delta Virus

support@deceraclinical.com (Coleman I. Smith MD, Lydia Tang MBChB) — Thu, 23 Feb 2023 21:35:00 +0000

In this episode, Coleman I. Smith, MD, and Lydia Tang, MBChB, discuss how to screen for hepatitis delta virus (HDV), including:

Algorithm for evaluation of HDV
Diagnosis of different stages of HDV infection
Strategies to increase HDV testing rates

Faculty:
Coleman I. Smith, MD
Professor of Medicine
Hepatologist
Georgetown Transplant Institute
Georgetown University
Washington, DC

Lydia Tang, MBChB
Assistant Professor
Department of Infectious Diseases
University of Maryland School of Medicine
Institute of Human Virology
Baltimore, Maryland

Link to full program:
http://bit.ly/41oYawr

Follow along with the slides at:
http://bit.ly/3XW6m4g

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Questions Answered on ART Safety and Tolerability in Pregnant People and Transgender Individuals

support@deceraclinical.com (Jill Blumenthal MD, William R. Short MD) — Thu, 23 Feb 2023 21:35:00 +0000

In this episode, Jill Blumenthal, MD, MAS, and William R. Short, MD, MPH, AAHIVS, address key considerations when evaluating ART safety and tolerability in pregnant people, those trying to conceive, and transgender individuals, such as:

Approaching patients trying to conceive on nonpreferred ART regimens (eg, 2-drug regimens like LA CAB and RPV)
Optimizing the use of the Antiretroviral Pregnancy Registry
Addressing unique barriers to ARV adherence in transgender individuals with HIV (eg, drug formulation considerations for ARV medications and gender-affirming hormone therapy, sperm banking or egg harvesting, drug coverage considerations)

Faculty:
Jill Blumenthal, MD, MAS
Associate Professor of Medicine
Infectious Diseases and Global Public Health
University of California, San Diego
San Diego, California

William R. Short, MD, MPH, AAHIVS
Associate Professor of Medicine
Division of Infectious Diseases
Department of Medicine
Perelman School of Medicine at the University of Pennsylvania
Philadelphia, Pennsylvania

Link to full program:
http://bit.ly/3PM3nYe

Link to downloadable slides:
http://bit.ly/3WgYycz

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Australian Perspectives on Advances in HIV

support@deceraclinical.com (Sharon Lewin AO FRACP PhD FAHMS, Don Smith MD) — Fri, 17 Feb 2023 21:40:00 +0000

In this episode, 2 Australian HIV experts share their thoughts on some of the most important HIV insights gained during the past year in the context of HIV care in Australia.

Specifically, the faculty discuss the continued dominance of second-generation INSTI-based regimens as mainstay HIV therapy in Australia, including in both 2-drug and 3-drug oral regimens; the emergence of 2-drug long-acting injectable therapy as a switch strategy; key aspects of successfully expanded oral PrEP programs in the region; the potential role of long-acting injectable PrEP; and key new advances in HIV cure research.

Presenters:

Sharon R. Lewin, AO, FRACP, PhD, FAHMS
Director, The Peter Doherty Institute for Infection and Immunity
Professor of Infectious Diseases
University of Melbourne
Consultant Infectious Diseases Physician
Alfred Hospital and Royal Melbourne Hospital
Melbourne, Australia

Don Smith, MD
Conjoint Professor
School of Population Medicine
University of New South Wales
Senior Staff Specialist
Albion Centre
South Eastern Sydney Local Health Network
Sydney, Australia

Content based on an online program supported by an independent educational grant from Gilead Sciences, Inc. and ViiV Healthcare.

Link to full program:
http://bit.ly/3YD8T4E

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Canadian Perspectives on Advances in HIV Treatment and Prevention

support@deceraclinical.com (Jean-Guy Baril MD, Alexander Wong MD) — Fri, 17 Feb 2023 21:40:00 +0000

In this episode, Canadian HIV experts share their thoughts on some of the most important new insights from HIV treatment and prevention research over the past year.

Specifically, the faculty discuss treatment strategies for patients with a history of NRTI resistance based on findings from the 2SD and NADIA trials; the latest data informing the use of 2-drug oral and injectable treatment regimens; prevention approaches for HIV and other sexually transmitted infections based on findings from the DoxyPEP, HPTN 083, and HPTN 084 trials; and other emerging innovations in HIV care.

Presenters:
Jean-Guy Baril, MD
Associate Professor
Family Medicine
Université de Montreal
Montreal, Quebec, Canada

Alexander Wong MD, FRCPC
Associate Professor
Department of Medicine
University of Saskatchewan
Regina, Saskatchewan, Canada

Content based on an online program supported by an independent educational grant from Gilead Sciences, Inc. and ViiV Healthcare.

Link to full program:
http://bit.ly/3YD8T4E

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Perspectives From Latin America on Advances in HIV PrEP

support@deceraclinical.com (Claudia P. Cortes MD, Beatriz Grinsztejn MD) — Fri, 17 Feb 2023 21:40:00 +0000

In this episode, 2 HIV experts from Latin America share their thoughts on the current status of HIV prevention strategies in the region, including recent successes and ongoing challenges. Specifically, the faculty discuss:

Barriers that limit PrEP availability in many regions of Latin America despite the high need among vulnerable and at-risk groups
Successful expansion of PrEP access in Brazil
Key findings from the prospective ImPrEP study evaluating implementation of same-day oral PrEP among men who have sex with men and transgender women in Brazil, Mexico, and Peru
What long-acting PrEP could mean for at-risk groups in Latin America when it becomes available
Important considerations for PrEP among TGW

Presenters:

Claudia P. Cortes MD
Associate Professor
Infectious Diseases
Universidad de Chile
Santiago, Chile

Beatriz Grinsztejn MD, PhD
Diretora, STD/HIV Clinical Research Laboratory
Instituto Nacional de Infectologia Evandro Chagas
Oswaldo Cruz Foundation
Rio de Janeiro, Brazil

Content based on an online program supported by an independent educational grant from Gilead Sciences, Inc. and ViiV Healthcare.

Link to full program:
http://bit.ly/3YD8T4E

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European Perspectives on Advances in HIV Treatment

support@deceraclinical.com (Jürgen K Rockstroh MD, Alexandra Calmy MD FMH PhD) — Fri, 17 Feb 2023 17:00:00 +0000

In this episode, 2 European HIV experts share their thoughts on some of the most important new antiretroviral therapy insights from HIV research over the past year.

Specifically, the faculty discuss findings from real-world and long-term studies of 2-drug oral regimens, the latest on 2-drug long-acting injectable therapy, how 2-drug options fit into rapid start strategies, and other new and emerging innovations in HIV treatment, including the availability of lenacapavir for multidrug-resistant HIV treatment and resumption of islatravir clinical development.

Presenters:

Jürgen K. Rockstroh, MD
Professor of Medicine
University Hospital Bonn
Department of Medicine I
Bonn, Germany

Alexandra Calmy, MD, FMH, PhD
HIV/AIDS Unit Director
Infectious Diseases Division
Geneva University Hospitals
University of Geneva
Geneva, Switzerland

Content based on an online program supported by an independent educational grant from Gilead Sciences, Inc. andViiV Healthcare.

Link to full program:
http://bit.ly/3Hz0jNa

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Diagnosis and Management of Patients With Long COVID

support@deceraclinical.com (Alba Azola MD, Monica Verduzco Gutierrez MD) — Tue, 31 Jan 2023 21:40:00 +0000

In this episode, Alba Azola, MD, and Monica Verduzco-Gutierrez, MD, discuss diagnosis and management of long COVID, including:

Definitions of post COVID conditions
Diagnosis, including symptoms and clinical presentation
Epidemiology
Risk factors
Possible treatment options
Clinical guidance statements

Presenters:

Alba Azola, MD
Assistant Professor
Department of Physical Medicine and Rehabilitation
Johns Hopkins
Co-Director
Johns Hopkins Post Acute COVID Team Clinic
Baltimore, Maryland

Monica Verduzco-Gutierrez, MD
Professor and Distinguished Chair
Department of Rehabilitation Medicine
University of Texas Health Science Center at San Antonio
Director, UT Health COVID-19 Recovery Clinic
Department of Rehab Medicine
UT Health San Antonio
San Antonio, Texas

Link to full program:
https://bit.ly/3Gn4tXO

Links to Consensus Guidance Statements on Assessment and Treatment of Post-Acute Sequelae of COVID-19:

Autonomic Dysfunction:
https://bit.ly/3GHeUGY

Cardiovascular Complications:
https://bit.ly/3CmupkX

Cognitive Symptoms:
https://bit.ly/3X9tnkw

Fatigue:
https://bit.ly/3ihiLRQ

Respiratory Sequelae:
https://bit.ly/3IrUkMc

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The Role of College Campuses in HIV PrEP Uptake

support@deceraclinical.com (Kenric Ware PharmD AAHIVP) — Tue, 31 Jan 2023 21:35:00 +0000

In this episode, Kenric Ware, PharmD, AAHIVP, discusses the role of college campuses in HIV pre-exposure prophylaxis (PrEP) uptake for adolescents, including the following.

PrEP awareness and education
Venues for ongoing PrEP conversations, including in-person dormitory discussions, virtual webinars, and social media conversations
Campus health clinics that are safe and trusting and minimize stigma
Individualized approaches, including:
Engaging local students in discussions of regional barriers and facilitators to PrEP uptake on their campus
Recruiting PrEP ambassadors with social capital on campus, such as student athletes or sorority or fraternity leaders
Identifying faculty and administrator PrEP champions to amplify and provide continuity and support to student PrEP messaging

Kenric Ware, PharmD, AAHIVP
Associate Professor
Department of Pharmacy Practice
South University
Savannah, Georgia
Chairperson, Pharmacist
Board of Directors
Joseph H. Neal Health Collaborative
Columbia, South Carolina

See the full program at:
http://bit.ly/3WhbBvZ

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How Clinic Facilities Can Prepare for Long-Acting Injectable Antiretroviral Therapy

support@deceraclinical.com (Eric Florence MD PhD) — Wed, 18 Jan 2023 21:30:00 +0000

In this episode, Eric Florence, MD, PhD, discusses how clinics can prepare for the implementation of long-acting injectable antiretroviral therapy, including:

Clinical infrastructure
Ensuring adequate space and injection equipment
Maintaining drug supply and temperature requirements
Staffing
Ensuring there are staff able to focus on the implementation of LA ART, including well-trained nurses to administer the injections
Implementing a system for scheduling follow-up injections and providing patient reminders
Having knowledgeable staff available to answer patient questions on their LA ART

Eric Florence, MD, PhD
Physician
Internal Medicine, Infectious Diseases & Tropical Medicine
University Hospital of Antwerp
Edegem, Brussels, Belgium

See the full program at:
https://bit.ly/3CsSvdX

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Questions Answered on ART Safety and Tolerability in Aging Patients and Populations With Cardiometabolic Toxicities

support@deceraclinical.com (Marta Boffito MD PhD FRCP, Jens Lundgren MD DMSc) — Tue, 17 Jan 2023 21:30:00 +0000

In this episode, Marta Boffito, MD, PhD, FRCP, and Jens D. Lundgren, MD, DMSc, address key considerations when evaluating antiretroviral therapy safety and tolerability in aging patients and those with possible cardiometabolic toxicities, including:

Monitoring for cardiometabolic syndromes (eg, lipid panels, coronary artery calcification scores)
Approaching antiretroviral-related weight gain in clinical practice
Interpreting results from RESPOND on cardiovascular risk with integrase strand transfer inhibitors
Collaborating with other specialties (eg, cardiologists, dietitians) to provide a multidisciplinary approach for managing comorbidities, including prevention and management

Faculty:

Marta Boffito, MD, PhD, FRCP
Consultant Physician/Professor
HIV/Research
Chelsea and Westminster Hospital
Imperial College London
London, United Kingdom

Jens D. Lundgren, MD, DMSc
Professor
Rigshospital, University of Copenhagen
Director
Centre of Excellence for Health, Immunity and Infection (CHIP)
Rigshospital, University of Copenhagen
Copenhagen, Denmark

Link to full program:
http://bit.ly/3PM3nYe

Link to downloadable slides:
http://bit.ly/3WgYycz

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Emerging Insights on Outpatient Management of Acute COVID-19 and Long COVID in Europe

support@deceraclinical.com (Jens Lundgren MD DMSc, Barbara Rath MD PhD HDR) — Fri, 13 Jan 2023 21:30:00 +0000

In this episode, Jens D. Lundgren, MD, DMSc, and Barbara Rath, MD, PhD, HDR, discuss emerging insights on outpatient management of acute COVID-19 and long COVID in Europe, including:

Current COVID-19 variant and subvariant landscape
COVID-19 treatments, including antivirals and monoclonal antibodies
ESCMID COVID-19 treatment guidelines
Long COVID causes and pathophysiology
Prevention and management of long COVID

Presenters:

Barbara Rath, MD, PhD, HDR
Co-founder and Chair
Vaccine Safety Initiative, Berlin, Germany/USA
Research Director
Université de Bourgogne-Franche-Comté, France
Executive Board Member
ESGREV (Respiratory Virus Study Group for ESCMID)
ISIRV Chair
ISIRV-Epidemiology Group

Follow along with the downloadable slideset at:
https://bit.ly/3IN1ScA

Link to full program:
http://bit.ly/3kb8pn4

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Administration of LA ART by Community Nurses in France

support@deceraclinical.com (Laurence Slama MD PhD) — Thu, 5 Jan 2023 21:45:00 +0000

In this episode, Laurence Slama, MD, PhD, describes some of the ways that her clinic is attempting to make IM injections of long-acting antiretroviral therapy more sustainable long term. She explains the logistics of how she has allowed for patients to receive their long-acting cabotegravir and rilpivirine doses through community nurses after receiving the first 3 doses in a clinical setting. She also discusses some of the benefits and challenges of this kind of flexible system for patients and healthcare professionals.

Laurence Slama
Doctor
Department of Infectious Diseases
Hôtel Dieu, APHP
Paris, France

See the full program at:
https://bit.ly/3CsSvdX

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PrEP Considerations for Transgender and Nonbinary Individuals

support@deceraclinical.com (Jill Blumenthal MD MAS) — Thu, 5 Jan 2023 21:20:00 +0000

In this episode, Jill Blumenthal, MD, MAS, discusses HIV pre-exposure prophylaxis (PrEP) considerations for transgender and nonbinary individuals, including:

Providing gender-affirming care
Integrating PrEP and gender care
Taking a sexual history and addressing sexual health
PrEP efficacy and options for transgender individuals, including FTC/TDF, FTC/TAF, and long-acting CAB
The importance of reassuring transgender individuals that data suggest there are no drug–drug interactions between gender-affirming hormone therapy and any of the PrEP options

Jill Blumenthal, MD, MAS (she/hers)
Associate Professor of Medicine
Infectious Diseases and Global Public Health
University of California, San Diego
San Diego, California

See the full program at:
https://bit.ly/3WhbBvZ

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Optimizing PrEP Selection and Persistence for MSM

support@deceraclinical.com (Jason Farley PhD MPH ANP BC FAAN FAANP AACRN) — Thu, 5 Jan 2023 21:20:00 +0000

In this episode, Jason E. Farley, PhD, MPH, ANP-BC, FAAN, FAANP, AACRN, discusses optimizing HIV pre-exposure prophylaxis (PrEP) selection and persistence for men who have sex with men (MSM), including:

Disparities in PrEP uptake for MSM
What healthcare professionals can do to address disparities in PrEP uptake
Providing PrEP within a program that includes sexual health and primary care services, in addition to prescribing PrEP
PrEP medication options for MSM
Helping patients access PrEP medications
Barriers to PrEP persistence
Strategies for aiding in PrEP persistence, including:
- Increasing access to healthcare professionals through text messaging and telemedicine
- Ensuring a welcome and sex-positive environment
- Partnering with pharmacists and community health workers for follow-up

Jason E. Farley, PhD, MPH, ANP-BC, FAAN, FAANP, AACRN
Professor
School of Nursing
Johns Hopkins University
Nurse Practitioner
Department of Infectious Diseases
John G. Bartlett Specialty Practice
Baltimore, Maryland

See the full program at:
https://bit.ly/3WhbBvZ

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What Strategies Are Most Promising for Prevention and Treatment of Long COVID in Nonhospitalized Patients?

Wed, 4 Jan 2023 19:00:00 +0000

Fernando Carnavali, MD; Rasika Karnik, MS, MD; and Renslow Sherer, MD, discuss long COVID, including:

Long COVID prevention strategies, including COVID-19 vaccination
Long COVID treatment approaches
Strategies for management of patients with long COVID

Presenters:
Fernando Carnavali, MD
Associate Professor of Medicine
Division Chief
General Internal Medicine
Department of Medicine
Site Director
COVID Center of Excellence Satellite-Ansonia
Mount Sinai Health
New York, New York

Rasika Karnik, MS, MD
Assistant Professor
Division of Primary Care
Department of Internal Medicine
University of Chicago
Medical Director
Post-COVID Recovery Clinic
Chicago, Illinois

Renslow Sherer, MD
Director
International HIV Training Center
Professor of Medicine
Section of Infectious Diseases and Global Health
Department of Medicine
University of Chicago
Chicago, Illinois

Link to slides:
https://bit.ly/3hXMgId

Link to full program:
https://bit.ly/3G271KL

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Should We Be Concerned About Resistance and Development of New Variants With COVID-19 Antiviral Therapy?

Wed, 4 Jan 2023 19:00:00 +0000

Fernando Carnavali, MD; Rasika Karnik, MS, MD; Renslow Sherer, MD; and Joseph Torrisi, PharmD, BCIDP, discuss COVID-19 treatments and the possibility for antiviral resistance, including:

Treatment resistance mechanisms
COVID-19 testing
COVID-19 treatments, including antivirals and monoclonal antibodies

Rasika Karnik, MS, MD
Assistant Professor
Division of Primary Care
Department of Internal Medicine
University of Chicago
Medical Director
Post-COVID Recovery Clinic
Chicago, Illinois

Joseph Torrisi, PharmD, BCIDP
Clinical Pharmacy Specialist
Infectious Diseases
Pharmacy
Grady Health System
Atlanta, Georgia

Link to slides:
https://bit.ly/3hXMgId

Link to full program:
https://bit.ly/3G271KL

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Should We Be Concerned About Viral Rebound With Antiviral Agents?

Fri, 30 Dec 2022 21:30:00 +0000

Fernando Carnavali, MD; Rasika Karnik, MS, MD; Renslow Sherer, MD; and Joseph Torrisi, PharmD, BCIDP, discuss COVID-19 rebound, including:

Prevalence of COVID-19 rebound
COVID-19 rebound and antiviral use
Management of COVID-19 rebound

Presenters:

Fernando Carnavali, MD
Associate Professor of Medicine
Division Chief
General Internal Medicine
Department of Medicine
Site Director
COVID Center of Excellence Satellite-Ansonia
Mount Sinai Health
New York, New York

Rasika Karnik, MS, MD
Assistant Professor
Division of Primary Care
Department of Internal Medicine
University of Chicago
Medical Director
Post-COVID Recovery Clinic
Chicago, Illinois

Joseph Torrisi, PharmD, BCIDP
Clinical Pharmacy Specialist
Infectious Diseases
Pharmacy
Grady Health System
Atlanta, Georgia

Link to slides:
https://bit.ly/3hXMgId

Link to full program:
https://bit.ly/3G271KL

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ART Selection in Treatment-Naive PWH: Weight Gain Considerations

support@deceraclinical.com (Princy N Kumar MD FIDSA MACP) — Fri, 30 Dec 2022 21:30:00 +0000

In this episode, Princy N. Kumar, MD, FIDSA, MACP, discusses key considerations for selecting ART in treatment-naive persons with HIV. Her discussion includes a review of the following studies on ART and weight gain:

ADVANCE: men vs women receiving DTG + FTC/TAF, DTG + FTC/TDF, and EFV + FTC/TDF
Comparison of ART regimens (eg, INSTI-, NNRTI- and PI-based regimens) in a pooled analysis of 8 phase III randomized controlled trials
GEMINI-1 and GEMINI-2: DTG + 3TC vs DTG + FTC/TDF

Presenter:
Princy N. Kumar, MD, FIDSA, MACP
Professor of Medicine and Microbiology
Chief, Division of Infectious Diseases and Travel Medicine
Senior Associate Dean of Students
Georgetown University School of Medicine
Washington, DC

Content based on an online CME program supported by an independent educational grant from ViiV Healthcare.

Link to full program:
https://bit.ly/3VIsDTg

Follow along with the slides:
https://bit.ly/3PYy1zn

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Selecting First-line ART in Treatment-Naive Persons With HIV

support@deceraclinical.com (Princy N Kumar MD FIDSA MACP) — Thu, 29 Dec 2022 23:00:00 +0000

In this episode, Princy N. Kumar, MD, FIDSA, MACP, discusses key considerations for selecting ART in treatment-naive persons with HIV. Her discussion includes:

DHHS Treatment Guideline recommendations
Choosing among first-line recommended integrase inhibitors
Recommended regimens for rapid ART start
Select key studies in treatment-naïve adults:
- AMBER study of virologic response with DRV/COBI/FTC/TAF vs DRV/COBI + TFC/TDF
- DRIVE-AHEAD and DRIVE-FORWARD efficacy study results, including resistance analyses of DOR + 2 NRTIs vs EFV or (DRV + RTV) + 2 NRTIs
- Safety and efficacy results from GEMINI-1 and GEMINI comparing DTG + 3TC vs DTG + FTC/TDF
The current/possible role of boosted PIs and NNRTIs
Selection considerations between TDF and TAF

Presenter:
Princy N. Kumar, MD, FIDSA, MACP
Professor of Medicine and Microbiology
Chief, Division of Infectious Diseases and Travel Medicine
Senior Associate Dean of Students
Georgetown University School of Medicine
Washington, DC

Content based on an online CME program supported by an independent educational grant from ViiV Healthcare.

Link to full program:
https://bit.ly/3VIsDTg

Follow along with the slides:
https://bit.ly/3PYy1zn

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If Treatment Supply Is Limited in Future COVID-19 Viral Peaks, How Do We Ethically Prioritize Patients for Treatment?

Thu, 29 Dec 2022 22:40:00 +0000

Fernando Carnavali, MD; Rasika Karnik, MS, MD; Renslow Sherer, MD; and Joseph Torrisi, PharmD, BCIDP, discuss how to ethically prioritize patients for COVID-19 treatment when treatment supplies may be limited, including insights on:

Risk stratification
Medication acquisition
Drug interactions

Presenters:

Rasika Karnik, MS, MD
Assistant Professor
Division of Primary Care
Department of Internal Medicine
University of Chicago
Medical Director
Post-COVID Recovery Clinic
Chicago, Illinois

Joseph Torrisi, PharmD, BCIDP
Clinical Pharmacy Specialist
Infectious Diseases
Pharmacy
Grady Health System
Atlanta, Georgia

Link to slides:
https://bit.ly/3hXMgId

Link to full program:
https://bit.ly/3G271KL

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Promoting Meningococcal Vaccine Equity in Adolescent Patients

support@deceraclinical.com (Tamera Coyne Beasley MD MPH) — Thu, 29 Dec 2022 05:00:00 +0000

In this episode, Tamera Coyne-Beasley, MD, MPH, discusses strategies to address barriers to improve meningococcal vaccination rates by addressing social determinants of health and minimizing vaccine inequities, such as:

Working closely with members of the community, including community-based organizations and adolescent and young adult influencers
Involving all youth when designing vaccination outreach and messaging programs
Creating and evaluating the use of technology
Using graphics, voices, and videos, appealing to all languages, and learning styles
Acknowledging that racism exists in medicine and medical history
Informing individuals that many children, including undocumented immigrants and those who are uninsured or underinsured, may be eligible for free meningococcal vaccines through the Vaccines for Children program
Seeking ways to address the shortage of healthcare professionals

Faculty:
Tamera Coyne-Beasley, MD, MPH
Derrol Dawkins, MD Endowed Chair in Adolescent Medicine
Vice-Chair, Pediatrics
Professor of Pediatrics and Internal Medicine
Division Director
Adolescent Medicine
University of Alabama at Birmingham
Children's of Alabama
Birmingham, Alabama

Link to full program:
https://bit.ly/3T0GLG2

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Will New COVID-19 Vaccines Affect Risk Stratification?

support@deceraclinical.com (Fernando Carnavali MD, Renslow Sherer MD) — Tue, 27 Dec 2022 21:10:00 +0000

Fernando Carnavali, MD; Renslow Sherer, MD; and Joseph Torrisi, PharmD, BCIDP, discuss how new COVID-19 vaccines may affect risk stratification, including:

Omicron-specific vaccine
Role of vaccination in risk stratification

Presenters:

Joseph Torrisi, PharmD, BCIDP
Clinical Pharmacy Specialist
Infectious Diseases
Pharmacy
Grady Health System
Atlanta, Georgia

Link to slides:
https://bit.ly/3WDYeFK

Link to full program:
https://bit.ly/3WJdIbs

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The Future of Long-Acting HIV Care: What’s Still Needed

Thu, 22 Dec 2022 21:30:00 +0000

In this episode, an international expert panel shares their thoughts on what will be needed from future long-acting HIV treatment and prevention strategies to address populations who are not eligible for currently available long-acting options. The faculty members also discuss important considerations for leveraging long-acting HIV approaches to address care inequities across different populations.

Other episodes in this 4-part series cover additional aspects of long-acting antiretrovirals for HIV treatment and prevention, including key steps for switching patients to long-acting injectable cabotegravir plus rilpivirine for HIV treatment, such as selecting the most appropriate patients, introducing patients to the long-acting option, and preparing patients for what to expect from long-acting treatment in terms of efficacy, visit timing, and the injection experience; essential considerations for incorporating long-acting cabotegravir as an additional HIV pre-exposure prophylaxis option for appropriate individuals at high risk of acquiring HIV infection, such as the role of the lead-in phase, new guideline recommendations for monitoring during PrEP, and patient care and follow-up after PrEP discontinuation; and important considerations at the operational level for incorporating long-acting injectable ART into the HIV treatment armamentarium.

Presenters:
Babafemi Taiwo, MBBS
Gene Stollerman Professor of Medicine
Chief, Division of Infectious Diseases
Northwestern University
Feinberg School of Medicine
Chicago, Illinois

Yvonne Gilleece, MB BCh, BAO
Honorary Clinical Professor in HIV Medicine and Sexual Health
Department of Global Health & HIV
Brighton & Sussex Medical School
Consultant in HIV Medicine and Sexual Health
HIV Department
University Hospitals Sussex NHS Foundation Trust
Brighton, United Kingdom

Cristina Mussini, MD
Head of Department of Infectious Diseases and Tropical Medicine
Full Professor of Infectious Diseases
Infectious Diseases Clinics, University Hospital
University of Modena and Reggio Emilia
Modena, Italy

Darrell H. S. Tan, MD, FRCPC, PhD
Associate Professor
Division of Infectious Diseases
University of Toronto
Clinician-Scientist
Division of Infectious Diseases
St. Michael's Hospital
Toronto, Canada

Content based on an online CME/CE program supported by an independent educational grant from ViiV Healthcare.

Link to full program:
https://bit.ly/3P3uPBc

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Improving Access and Acceptance of HIV PrEP for People Who Inject Drugs

support@deceraclinical.com (Decera Clinical Education) — Tue, 20 Dec 2022 21:30:00 +0000

In this episode, Carolyn Chu, MD, MSc, FAAFP, AAHIVS, discusses improving HIV pre-exposure prophylaxis accessibility and availability for PWID, including by:

Integrating PrEP with services that PWID are already aware of and/or connected to (eg, harm reduction/syringe services and substance use disorder treatment programs, peer-based training/education initiatives, healthcare for the homeless programs, and emergency departments)
Staffing PrEP programs with people who are trusted by PWID and delivering PrEP in settings where patients feel respected, comfortable, and safe
Tailoring prescribing practices and interventions (eg, same-day medication initiation, on-site pharmacies and/or medication storage, and intensive outreach and navigation) to support the care needs of PWID

Carolyn Chu, MD, MSc, FAAFP, AAHIVS
Chief Medical Office
American Academy of HIV Medicine

See the full program at:
https://bit.ly/3WhbBvZ

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Answering the Questions on Monkeypox in PWH

support@deceraclinical.com (Chloe Orkin MBChB FRCP MD, Monica Gandhi MD MPH) — Mon, 19 Dec 2022 21:40:00 +0000

In this episode, Monica Gandhi, MD, MPH, and Chloe Orkin, MBChB, FRCP, MD, discuss considerations for monkeypox, now called mpox, in people with HIV, including:

The history of monkeypox (mpox)
The current monkeypox (mpox) outbreak
What we knew about monkeypox (mpox) in PWH prior to the current outbreak
Data in PWH from an international case series of monkeypox (mpox)
CDC data regarding monkeypox (mpox) in PWH
Monkeypox (mpox) treatment recommendations
Drug–drug interaction considerations between tecovirimat for monkeypox (mpox) and ART
Monkeypox (mpox) vaccination recommendations for PWH
Global access to monkeypox (mpox) treatments and vaccines
Whether monkeypox (mpox) is a sexually transmitted infection and the implications of that
Ongoing research on monkeypox (mpox) in PWH

Monica Gandhi, MD, MPH
Professor of Medicine
Division of HIV, Infectious Diseases, and Global Medicine
University of California, San Francisco
Medical Director
Ward 86 HIV Clinic
San Francisco General Hospital
San Francisco, California

Chloe Orkin, MBChB, FRCP, MD
Professor of HIV
Queen Mary, University of London
Consultant Physician
Lead for HIV Research
Barts Health NHS Trust
The Royal London Hospital
London, United Kingdom

Link to full program:
https://bit.ly/3HPu4Lk

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Answering the Questions on Considering an ART Switch During Pregnancy

support@deceraclinical.com (Annette Haberl MD, William R Short MD MPH AAHIVS) — Mon, 19 Dec 2022 21:35:00 +0000

In this episode, Annette Haberl, MD, and William R. Short, MD, MPH, AAHIVS, discuss when to consider an ART switch during pregnancy, including:

Current DHHS, EACS, WHO, BHIVA, and German/Austrian guidelines for the use of ARVs in pregnancy
What data and recommendations for the use of ARVs during pregnancy are currently missing from the guidelines
Available data on newer ARVs in the ARV pregnancy registry
Pharmacokinetic data for newer ARVs including BIC/FTC/TAF and LA CAB + RPV in pregnancy
Recommendations for 2-drug ART regimens in pregnancy
What to do when someone becomes pregnant on a newer ART regimen that is not yet recommended by the guidelines

Annette Haberl, MD
Physician
Head of HIV and Women
HIVCENTER Frankfurt
Department of Infectious Disease
Hospital of the Johann Wolfgang Goethe University
Frankfurt, Germany

Link to full program:
https://bit.ly/3HPu4Lk

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Expanding Access to Long-Acting ART in Europe

support@deceraclinical.com (Stephane De Wit MD PhD) — Mon, 19 Dec 2022 21:30:00 +0000

In this episode, Stephane De Wit, MD, PhD, discusses the benefits of long-acting antiretroviral therapy (ART) for migrant populations in Europe—and specifically in Belgium. He also addresses some of the challenges of accessing and following up with those populations.

Dr De Wit describes some of the ways that the Belgian healthcare system is set up to improve access to ART. He then explains some of the disease parameters for considering expanding the use of long-acting ART to patients who are not virologically suppressed. Finally, Dr De Wit offers some thoughts about the future of long-acting ART to migrant populations in Belgium.

Stephane De Wit, MD, PhD
Former Head
Infectious Diseases
Saint Pierre University Hospital
Brussels, Belgium

See the full program at:
https://bit.ly/3HIMAoF

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Whom to Screen for Hepatitis Delta Virus

support@deceraclinical.com (Nancy Reau MD, Coleman I Smith MD) — Thu, 15 Dec 2022 21:30:00 +0000

In this episode, Nancy Reau, MD, and Coleman I. Smith, MD, discuss the burden of undiagnosed hepatitis delta virus (HDV) infection and who should be tested, including:

Epidemiology of HDV infection
Clinical course of HDV infection
Populations at high risk of HDV infection
Guidelines for HDV testing

Faculty:
Nancy Reau, MD
Professor of Medicine
Chief, Section of Hepatology
Associate Director, Solid Organ Transplantation
Richard B. Capps Chair of Hepatology
Rush University Medical Center
Chicago, Illinois

Coleman I. Smith, MD
Professor of Medicine
Hepatologist
Georgetown Transplant Institute
Georgetown University
Washington, DC

Link to full program:
https://bit.ly/3WmJnzi

Follow along with the slides at:
https://bit.ly/3NpAYI1

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Hong Kong Perspective: Should Older Age Influence Hepatitis B Treatment Decisions?

Thu, 15 Dec 2022 21:30:00 +0000

When it comes to managing adults with HBV, should age factor into your treatment decision—or is it important to treat everyone, regardless of age?

Listen as Dr George Lau discusses these questions and more for strategizing the monitoring and treatment of older adults with HBV.

Presenter:
George Lau, MBBS (HKU), MD (HKU), FRCP (Edin, Lond), FAASLD (USA)
Chairman
Humanity and Health Medical Group
Hong Kong, China
Chair, Professor, and Co-Director
Liver Diseases & Transplant Centre
The Fifth Medical Centre of Chinese PLA General Hospital
Beijing, China

Link to full program:
https://bit.ly/3fg9fwB

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What Patients Want in HIV Treatment and Prevention: Africa

Wed, 14 Dec 2022 21:30:00 +0000

In this episode, Winnie Sseruma and Linda-Gail Bekker, MBChB, DTM&H, DCH, FCP(SA), PhD, discuss some of the barriers to genuinely patient-centered HIV care in Africa and offer calls to action for healthcare professionals for responding to patient preferences.

They discuss the efforts to improve patient-centered HIV care in the foundations and organizations for which they work. They also address issues related to stigma around HIV and complacency and lack of visibility for HIV.

You will then hear them talk through differentiated service delivery in South Africa and Mozambique as models for other parts of Africa. They focus on HIV prevention and some of the difficulties of reaching certain populations to better communicate effective prevention practices.

They end with a discussion about the importance of documenting the experiences and stories of people living with HIV.

Winnie Sseruma
International Development Consultant
London, United Kingdom

Linda-Gail Bekker, MBChB, DTM&H, DCH, FCP(SA), PhD
Director
Desmond Tutu HIV Centre
Past President
International AIDS Society
Faculty of Health Sciences
University of Cape Town
Cape Town, South Africa

Link to full program:
https://bit.ly/3Fxsfkz

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Addressing ART Safety and Tolerability in Transgender Individuals

support@deceraclinical.com (Jill Blumenthal MD MAS, Jennifer Cocohoba PharmD) — Wed, 7 Dec 2022 21:30:00 +0000

In this episode, Jill Blumenthal, MD, MAS, and Jennifer Cocohoba, PharmD, share how they manage possible antiretroviral (ARV)-associated toxicities in transgender individuals, including:

Strategies on how to approach different ARV-related toxicities
Other factors to consider when assessing possible ARV-related toxicities (eg, weight gain, cardiovascular disease), such as gender-affirming care and nonmedication risk factors (eg, smoking, life stressors)
Clinically relevant drug–drug interactions related to HIV and gender-affirming care
Methods to reduce barriers to ART adherence

Faculty:

Jill Blumenthal, MD, MAS
Associate Professor of Medicine
Infectious Diseases and Global Public Health
University of California, San Diego
San Diego, California

Jennifer Cocohoba, PharmD
Professor
Department of Clinical Pharmacy
University of California, San Francisco
Pharmacist
Women’s HIV Program
University of California San Francisco Medical Center
San Francisco, California

Link to full program:
https://bit.ly/3PM3nYe

Follow along with the slides at:
https://bit.ly/3NpAYI1

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What Patients Want in HIV Treatment and Prevention: Malaysia

support@deceraclinical.com (Iskandar Azwa MBChB, Andrew Tan Tze Tho) — Wed, 7 Dec 2022 21:30:00 +0000

In this episode, Iskandar Azwa, MBChB, and patient advocate Andrew Tan Tze Tho discuss barriers to genuinely patient-centered HIV care in Malaysia and the surrounding region and offer calls to action for healthcare professionals for responding to patient preferences.

They discuss health literacy programs and other forms of effective health communication, especially with respect to disparate communities. They also address the prevalence of late presentation in Malaysia and the importance of getting people tested and into care earlier.

They then discuss the urgency of rapid initiation of antiretroviral therapy, discrepancies in access to health services, and stigma and discrimination.

Finally, they discuss the issues preventing newer antiretrovirals from being more readily available to people in the region; the importance of maintaining and refining patient-focused, differentiated care in the face of such disparities; and the role of advocates and healthcare professionals in helping to drive those improvements.

Iskandar Azwa, MBChB
Associate Professor
Infectious Diseases, Faculty of Medicine
University of Malaya
Kuala Lumpur, Malaysia

Andrew Tan Tze Tho
President
Kuala Lumpur AIDS Support Services Society (KLASS)
Kuala Lumpur, Malaysia

Link to full program:
https://bit.ly/3Fxsfkz

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Practice-Changing Viral Hepatitis Data From AASLD 2022

support@deceraclinical.com (Nancy Reau MD) — Tue, 6 Dec 2022 21:30:00 +0000

In this episode, Nancy Reau, MD, shares her thoughts on the most practice-changing viral hepatitis data from AASLD 2022, including:

Novel therapeutics for HBV
HCV management strategies
HDV screening and linkage to care
Fatty liver disease in persons with viral hepatitis
Use of statins to decrease morbidity and mortality in persons with liver disease

Presenter:

Nancy Reau, MD
Professor of Medicine
Chief, Section of Hepatology
Associate Director
Solid Organ Transplantation
Richard B. Capps Chair of Hepatology
Rush University Medical Center
Chicago, Illinois

Link to full program:
https://bit.ly/3Y1tD6f

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FAQs: Improving Empiric Antibiotic Regimens for HABP/VABP in the ICU

Tue, 6 Dec 2022 21:30:00 +0000

In this episode, Marion Elligsen, BScPhm, MSc, RPh, ACPR; Keith S Kaye, MD, MPH; and Andrew Shorr, MD, MPH, MBA, discuss key considerations for selecting empiric antibiotic regimens in patients with HABP/VABP in the intensive care unit, including:

The role of novel β-lactam/β-lactamase inhibitor combinations
Use of clinical predictions scores (eg, Drug Resistance in Pneumonia [DRIP] score) to predict risk for pneumonia caused by multidrug-resistant pathogens
Application of rapid diagnostic testing in critically ill patients with pneumonia, including current limitations
Implementation of advanced antibiograms and clinical prediction scores
Clinical utility of biomarkers for pneumonia (eg, procalcitonin)
Application of updated nosocomial pneumonia classifications in clinical practice

Faculty:
Marion Elligsen, BScPhm, MSc, RPh, ACPR
Practice-Based Researcher
Sunnybrook Research Institute
Antimicrobial Stewardship Pharmacy Lead
Department of Pharmacy
Sunnybrook Health Sciences Centre
Toronto, Ontario, Canada

Keith S. Kaye, MD, MPH
Chief
Division of Allergy, Immunology and Infectious Diseases
Professor of Medicine
Rutgers Robert Wood Johnson Medical School
New Brunswick, New Jersey

Andrew Shorr, MD, MPH, MBA
Director
Pulmonary and Critical Care Medicine
Medstar Washington Hospital Center
Washington, DC

Content based on a CME program supported by an educational grant from Merck Sharp & Dohme Corp.

Link to full program:
https://bit.ly/3HaZpYw

Link to downloadable slideset:
https://bit.ly/3UxHoqr

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Newest Viral Hepatitis Data From AASLD 2022

support@deceraclinical.com (Stefan Zeuzem MD) — Tue, 6 Dec 2022 21:30:00 +0000

In this episode, Stefan Zeuzem, MD, discusses new viral hepatitis data from AASLD 2022, including:

Hepatitis B
Prevention of HBV vertical transmission when HBIg is unavailable
Therapeutic vaccination for HBV cure
Antiviral therapy to prevent HCC in patients with CHB in the indeterminate phase
Hepatitis delta
HDV prevalence in ethnically diverse, urban, safety-net populations
Bulevirtide ± pegIFN-α2a for chronic HDV in the French cATU study
Bulevirtide monotherapy for patients with HDV and compensated cirrhosis in the HEP4Di study
HDV functional cure with lonafarnib-based therapy
Hepatitis C
Integrated community HCV service for PWUD: the ITTREAT study
Helios-3 study of treatment of people with HCV by specialists or nonspecialists
Risk of HCC after SVR in patients with HCV

Presenter:

Stefan Zeuzem, MD
Professor of Medicine
Chief, Department of Medicine I
JW Goethe University Hospital
Frankfurt, Germany

Follow along with the downloadable slideset at:
https://bit.ly/3FxIOwZ

Link to full program:
https://bit.ly/3Y1tD6f

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Key HIV Studies Influencing My Practice Following IDWeek and HIV Glasgow 2022—Audio Recap

support@deceraclinical.com (Chloe Orkin MBChB FRCP MD, Babafemi Taiwo MBBS) — Mon, 5 Dec 2022 21:30:00 +0000

In this episode, Chloe Orkin, MBChB, FRCP, MD, and Babafemi Taiwo, MBBS, discuss new HIV data presented at IDWeek and HIV Glasgow 2022, including

Prevention strategies
LA therapies
Investigational agents

Presenters:

Babafemi Taiwo, MBBS
Gene Stollerman Professor of Medicine
Chief, Division of Infectious Diseases
Northwestern University
Feinberg School of Medicine
Chicago, Illinois

Content based on an online CME/CE program supported by an independent educational grant from Gilead Sciences, Inc.;
Janssen Therapeutics, Division of Janssen Products, LP; and ViiV Healthcare.

Link to full program:
https://bit.ly/3iFEF0T

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COVID-19 Antiviral Agents and COVID-19 Rebound

Tue, 22 Nov 2022 21:30:00 +0000

In this episode, Jason Gallagher, PharmD, and Emily Heil, PharmD, MS, BCIDP discuss landmark clinical trials of COVID-19 antivirals for nonhospitalized patients and COVID-19 rebound phenomenon, including:

EPIC-HR study of nirmatrelvir plus ritonavir
PINETREE study of remdesivir
MOVe-OUT and Panoramic studies of molnupiravir
COVID-19 rebound in treated and untreated patients

Presenters:

Jason Gallagher, PharmD
Clinical Professor
School of Pharmacy
Temple University
Clinical Pharmacy Specialist
Infectious Diseases
Temple University Hospital
Philadelphia, Pennsylvania

Emily Heil, PharmD, MS, BCIDP, AAHIVP
Associate Professor
Department of Pharmacy Practice and Science
University of Maryland School of Pharmacy
Infectious Diseases Clinical Pharmacy Specialist
University of Maryland Medical Center
Baltimore, Maryland

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Key COVID-19 Studies Influencing My Practice Following IDWeek 2022—Audio Recap

support@deceraclinical.com (Princy N Kumar MD FIDSA MACP, Paul E Sax MD) — Fri, 18 Nov 2022 21:30:00 +0000

In this episode, Princy N. Kumar, MD, and Paul E. Sax, MD, discuss new COVID-19 data from IDWeek 2022, including:

COVID-19 vaccines, including omicron BA.1 bivalent booster
Risk factors for breakthrough COVID-19 infections
COVID-19 diagnostics, including digital droplet PCR
COVID-19 therapeutics, including:
- Nirmatrelvir plus ritonavir
- Tixagevimab plus cilgavimab
- Baricitinib
- Tocilizumab
- Inhaled interferon β-1a
COVID-19 therapeutics and outcomes in patients with immunocompromise
Long COVID

Presenters:
Princy N. Kumar, MD, FIDSA, MACP
Professor of Medicine and Microbiology
Chief, Division of Infectious Diseases and Travel Medicine
Senior Associate Dean of Students
Georgetown University School of Medicine
Washington, DC

Paul E. Sax, MD
Clinical Director
HIV Program and Division of Infectious Diseases
Brigham and Women’s Hospital
Professor of Medicine
Harvard Medical School
Boston, Massachusetts

Follow along with the downloadable slideset at:
http://bit.ly/3gkJI67

Link to full program:
http://bit.ly/3TSVthM

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Creative Strategies for Meningococcal Vaccine Uptake

support@deceraclinical.com (Nneka Holder MD MPH) — Thu, 17 Nov 2022 21:30:00 +0000

In this episode, Nneka Holder, MD, MPH, shares various strategies to improve meningococcal vaccine uptake in adolescent patients, including:

Use of school vaccine mandates beyond entry requirements
Promote more frequent visits by incorporating immunization platforms and using text or email reminders to bring patients back to the office
Schedule follow-up visits before patients leave the office to increase retention
Increase access and convenience by:
- Implementing quick, immunization-only visits
- Promoting use of alternative vaccinations sites (eg, school gyms, local pharmacies) for meningococcal booster doses
Address vaccine hesitancy, ensuring patients and parents have a voice in how their healthcare is managed
Continue to bring up the importance of meningococcal vaccines at every visit even after vaccine refusal

Faculty:

Nneka Holder, MD, MPH
Associate Professor
Department of Pediatrics
MedStar Georgetown University Hospital
Washington, DC

Link to full program:
https://bit.ly/3T0GLG2

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Barriers and Solutions to Expanding PrEP Uptake: Solutions

support@deceraclinical.com (Timothy Wilkin MD MPH) — Tue, 15 Nov 2022 21:00:00 +0000

This is 1 of 6 short episodes taken from a webinar on barriers and solutions to expanding pre-exposure prophylaxis (PrEP) uptake in the comprehensive program “Contemporary HIV Treatment and Prevention 2022.” In this episode, Timothy J. Wilkin, MD, MPH, discusses solutions to expanding PrEP uptake. His discussion includes:

Potential healthcare professional barriers to prescribing PrEP
Addressing the gap in PrEP training for healthcare professionals
Expanding PrEP options to facilitate adherence and persistence: today and in the near future
Immediate PrEP initiation at New York City sexual health clinics
Providing PrEP by telehealth
Take-home points on expanding PrEP uptake

Presenter:

Timothy J. Wilkin, MD, MPH
Professor of Medicine
Division of Infectious Diseases
Weill Medical College of Cornell University
New York, New York

Link to full program:
http://bit.ly/3UFUl2b

Follow along with the slides at:
https://bit.ly/3EcaYg0

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Barriers and Solutions to Expanding PrEP Uptake: Cisgender Women

support@deceraclinical.com (Timothy Wilkin MD MPH) — Tue, 15 Nov 2022 18:00:00 +0000

This is 1 of 6 short episodes taken from a webinar on barriers and solutions to expanding pre-exposure prophylaxis (PrEP) uptake in the comprehensive program “Contemporary HIV Treatment and Prevention 2022.” In this episode, Timothy J. Wilkin, MD, MPH, discusses PrEP uptake for cisgender women. His discussion includes:

Prevalence of PrEP use in cisgender women in the United States
Barriers to PrEP uptake in cisgender women
Implementation of PrEP within family planning clinics in Atlanta
PrEP in pregnancy and breastfeeding

Presenter:

Timothy J. Wilkin, MD, MPH
Professor of Medicine
Division of Infectious Diseases
Weill Medical College of Cornell University
New York, New York

Link to full program:
http://bit.ly/3UFUl2b

Follow along with the slides at:
http://bit.ly/3TDOPM8

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Barriers and Solutions to Expanding PrEP Uptake: Transgender Women

support@deceraclinical.com (Timothy Wilkin MD MPH) — Tue, 15 Nov 2022 18:00:00 +0000

This is 1 of 6 short episodes taken from a webinar on barriers and solutions to expanding pre-exposure prophylaxis (PrEP) uptake in the comprehensive program “Contemporary HIV Treatment and Prevention 2022.” In this episode, Timothy J. Wilkin, MD, MPH, focuses on transgender women. His discussion includes:

Barriers to PrEP uptake in transgender women
High PrEP adherence among transgender women and transfeminine individuals in a real-world healthcare setting in New York City

Presenter:

Timothy J. Wilkin, MD, MPH
Professor of Medicine
Division of Infectious Diseases
Weill Medical College of Cornell University
New York, New York

Link to full program:
http://bit.ly/3UFUl2b

Follow along with the slides at:
https://bit.ly/3EcaYg0

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Barriers and Solutions to Expanding PrEP Uptake: People Who Inject Drugs

support@deceraclinical.com (Timothy Wilkin MD MPH) — Tue, 15 Nov 2022 18:00:00 +0000

This is 1 of 6 short episodes taken from a webinar on barriers and solutions to expanding pre-exposure prophylaxis (PrEP) uptake in the comprehensive program “Contemporary HIV Treatment and Prevention 2022.” In this episode, Timothy J. Wilkin, MD, MPH, discusses barriers to PrEP uptake for people who inject drugs. His discussion includes:

PrEP uptake and recommendations for people who inject drugs
Project SHE: integrating PrEP with community-based syringe services for women who inject drugs

Presenter:

Timothy J. Wilkin, MD, MPH
Professor of Medicine
Division of Infectious Diseases
Weill Medical College of Cornell University
New York, New York

Link to full program:
http://bit.ly/3UFUl2b

Follow along with the slides at:
https://bit.ly/3EcaYg0

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Barriers and Solutions to Expanding PrEP Uptake: PrEP Inequities by Race

support@deceraclinical.com (Timothy Wilkin MD MPH) — Mon, 14 Nov 2022 23:00:00 +0000

This is 1 of 6 short episodes taken from a webinar on barriers and solutions to expanding pre-exposure prophylaxis (PrEP) uptake in the comprehensive program “Contemporary HIV Treatment and Prevention 2022.” In this episode, Timothy J. Wilkin, MD, MPH, discusses barriers to PrEP uptake in the context of racial inequities, specifically for Black and Latinx communities. His discussion includes:

Inequities in PrEP uptake in Black and Hispanic and Latinx people compared with White people
Structural barriers to PrEP adoption
Kaiser Permanente study (2012-2019): PrEP continuum of care and new HIV infections
Ele[MEN]t study: PrEP persistence and discontinuation in young Black men who have sex with men
Creating change: education of patients and healthcare professionals to address inequities in PrEP uptake

Presenter:

Timothy J. Wilkin, MD, MPH
Professor of Medicine
Division of Infectious Diseases
Weill Medical College of Cornell University
New York, New York

Link to full program:
https://bit.ly/3VIsDTg

Follow along with the slides at:
https://bit.ly/3EcaYg0

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Linkage to Care After HBV Diagnosis in Asian Communities in the US

Mon, 14 Nov 2022 21:30:00 +0000

This episode is part of a larger discussion that comes from “Partnering With Patients: Overcoming Barriers to HBV Care in Asian Communities in the US.” Hear from Thuan Vu, MD, as he discusses linkage to care after HBV diagnosis in Asian communities from a provider’s perspective. And listen to discussions with Jennifer Wild, MSN, BSN, RN, OCN, and Melinda Tran as they consider his story from a patient advocacy point of view.

Topics include barriers to linkage to care like social stigma, lack of insurance coverage, financial support, and a lack of physicians who speak the patient’s native language.

Link to full program:
https://bit.ly/3Gf7NWo

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Cutting-Edge Concepts in HIV Care: PrEP

support@deceraclinical.com (Paul E. Sax MD) — Mon, 14 Nov 2022 21:30:00 +0000

In this episode, Paul E. Sax, MD, discusses the latest recommendations and options for HIV pre-exposure prophylaxis (PrEP), including:

CDC PrEP guideline 2021 updates for oral PrEP
The ANRS IPERGAY study: on-demand oral emtricitabine (FTC)/tenofovir disoproxil fumarate (TDF) PrEP in men who have sex with men who are at high risk for HIV infection
A review of the HPTN 083 and 084 studies: efficacy and safety of long-acting (LA) injectable cabotegravir (CAB) vs daily oral FTC/TDF for PrEP
1-year follow-up after unblinding for HPTN 083 and 084
LA CAB for PrEP: monitoring and safety
Stopping LA CAB for PrEP

Presenter:

Paul E. Sax, MD
Clinical Director
HIV Program and Division of Infectious Diseases
Brigham and Women’s Hospital
Professor of Medicine
Harvard Medical School
Boston, Massachusetts

Link to full program:
https://bit.ly/3VIsDTg

Follow along with the slides at:
https://bit.ly/3Gh9AKG

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Cutting-Edge Concepts in HIV Care: Long-Acting Therapies

support@deceraclinical.com (Paul E. Sax MD) — Mon, 14 Nov 2022 21:30:00 +0000

In this episode, Paul E. Sax, MD, discusses long-acting (LA) injectables for HIV treatment, including:

Guidance on the use of LA cabotegravir (CAB) + rilpivirine (RPV)
Risk factors for virologic failure of LA CAB + RPV
The ATLAS-2M study
Combined clinical trials of LA CAB + RPV
Practical considerations for LA CAB + RPV
Implementation of LA CAB + RPV
Switching to LA CAB + RPV without an oral lead-in, including a discussion of the FLAIR extension study
Supporting candidates for LA antiretroviral therapy (ART)
Discussion of an implementation study of LA CAB + RPV in patients with challenges to oral ART adherence in San Francisco
Future LA ART
The investigational LA HIV capsid inhibitor lenacapavir (LEN)
LEN resistance from the CAPELLA and CALIBRATE studies
LEN injection-site reactions in the CAPELLA and CALIBRATE studies

Presenter:

Paul E. Sax, MD
Clinical Director
HIV Program and Division of Infectious Diseases
Brigham and Women’s Hospital
Professor of Medicine
Harvard Medical School
Boston, Massachusetts

Link to full program:
https://bit.ly/3VIsDTg

Follow along with the slides at:
http://bit.ly/3Gh9AKG

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Ending the HIV Epidemic: Persistence on ART

Mon, 14 Nov 2022 20:30:00 +0000

In this episode, Linda-Gail Bekker, MBChB, DTM&H, DCH, FCP(SA), PhD, discusses strategies for and importance of HIV care engagement and reengagement for those who have fallen out of care. Her overview includes:

WHO Global Health Strategy on HIV
Longitudinal HIV care trajectories
Promotion of successful care and antiretroviral therapy (ART) adherence
Differentiated service delivery
Improving care and ART adherence in high-risk groups
Patient perspectives on ART persistence

Presenter:
Linda-Gail Bekker, MBChB, DTM&H, DCH, FCP(SA), PhD
Director
Desmond Tutu HIV Centre
Past President
International AIDS Society
Faculty of Health Sciences
University of Cape Town
Cape Town, South Africa

Panelists:
Nagalingeswaran Kumarasamy, MBBS, FRCP, PhD
Chief and Director
VHS-Infectious Diseases Medical Centre
Director
Chennai Antiviral Research and Treatment (CART) Clinical Research Site
Voluntary Health Services
Chennai, India

Babafemi Taiwo, MBBS
Gene Stollerman Professor of Medicine
Chief, Division of Infectious Diseases
Northwestern University
Feinberg School of Medicine
Chicago, Illinois

Content based on an online CME program supported by an independent educational grant from Gilead Sciences.

Follow along with the slides:
https://bit.ly/3dSNoum

Link to full program:
https://bit.ly/3AE2AV1

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Treatment Barriers in Asian Communities in the US

Mon, 14 Nov 2022 20:20:00 +0000

This episode is part of a larger discussion that comes from “Partnering With Patients: Overcoming Barriers to HBV Care in Asian Communities in the US.” First, Melinda Tran discusses treatment and retention of HBV care in Asian Communities in the US with Jennifer Wild, MS, BSN, RN, OCN, and Thuan Vu, MD. Their conversation offers an interesting mix of insights from the point of view of patient advocates and healthcare providers.

Topics include barriers to treatment—like a lack of insurance coverage and financial support, complexities in treatment guidelines, psychosocial factors—and addressing practical solutions to these barriers.

Link to full program
http://bit.ly/3Gf7NWo

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HBV Treatment and Retention in Care Among African Communities in the US

Mon, 14 Nov 2022 20:10:00 +0000

Patient advocate Bright Ansah shares some issues he encountered while seeking treatment after his diagnosis with HBV, including limited follow-up on lab results and a lack of compassion from his healthcare providers, and rushed health appointments.

Bright’s story opens up a conversation about broader concerns about HBV treatment and retention in care with Janet Afoakwah and William Amiteye, fellow patient advocates on the panel, and Patricia D. Jones, MD, MSCR, who offers a healthcare provider’s perspective. They also discuss practical solutions to those barriers, including ways to establish trust with the patient, emphasizing active listening and compassionate care during appointments, and collaborating with patients on their options and next steps.

Link to full program:
http://bit.ly/3Gf7NWo

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HBV Screening and Diagnosis Among African Communities in the US

Mon, 14 Nov 2022 20:00:00 +0000

Listen as patient advocate William Amiteye uses his own experience as a Tanzanian immigrant to discuss important barriers to effective HBV screening and diagnosis, including limited knowledge about HBV from his healthcare providers, a lack of compassion toward his diagnosis from those same providers, and a limited awareness of HBV from patients in general.

His story opens up an interesting and important discussion with another patient advocate on the panel, Janet Afoakwah, and Patricia D. Jones, MD, MSCR, who provides a provider’s perspective on the topic.

Link to full program:
http://bit.ly/3Gf7NWo

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Barriers and Solutions to Expanding PrEP Uptake: Adolescents

support@deceraclinical.com (Decera Clinical Education) — Mon, 7 Nov 2022 21:30:00 +0000

This is 1 of 6 short episodes taken from a webinar on barriers and solutions to expanding pre-exposure prophylaxis (PrEP) uptake in the comprehensive program “Contemporary HIV Treatment and Prevention 2022.” In this episode, Timothy J. Wilkin, MD, MPH, discusses barriers to PrEP uptake for adolescents. His discussion includes:

How PrEP is underused in adolescents and young adults
Healthcare professional barriers to provision of PrEP for adolescents
A systematic review and meta-analysis of adherence to PrEP in adolescents and young adults
Barriers to adherence in adolescents and young adults
Interventions to support PrEP adherence in adolescents

Presenter:

Timothy J. Wilkin, MD, MPH
Professor of Medicine
Division of Infectious Diseases
Weill Medical College of Cornell University
New York, New York

Link to full program:
https://bit.ly/3VIsDTg

Follow along with the slides at:
https://bit.ly/3EcaYg0

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ART Safety Considerations in Aging Patients With HIV

support@deceraclinical.com (Marta Boffito MD PhD FRCP, Julian Falutz MD FRCPC) — Wed, 2 Nov 2022 20:30:00 +0000

In this episode, hear Marta Boffito, MD, PhD, FRCP, and Julian Falutz, MD, FRCPC, discuss their approach to minimizing antiretroviral (ARV)-related intolerances in older patients with HIV, including:

Consequences of polypharmacy
Deprescribing ARV and non-ARV medications
Complications associated with aging (eg, geriatric syndromes such as falls, frailty, multimorbidity)
Mediations to avoid, such as anticholinergic medications, to minimize drug–drug interactions and risk of developing geriatric syndromes

Faculty:

Marta Boffito, MD, PhD, FRCP
Consultant Physician/Professor
HIV/Research
Chelsea and Westminster Hospital
Imperial College London
London, United Kingdom

Julian Falutz, MD, FRCPC
Associate Professor of Medicine
Department of Medicine
McGill University School of Medicine
Director
Comprehensive HIV and Aging Initiative
Chronic Viral Illness Service
McGill
Montreal, Quebec, Canada

Link to full program:
https://bit.ly/3PM3nYe

Follow along with the slides at:
https://bit.ly/3NpAYI1

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If RSV Vaccines Are Approved for Older Adults, What’s Next?

Wed, 2 Nov 2022 20:30:00 +0000

An RSV vaccine, if approved, may reduce disease burden in older adults. In this recap of the most common questions from a symposium at the Family Medicine Experience 2022 conference, listen as we discuss when an RSV vaccine may be approved and how to overcome barriers to the implementation of vaccines for older adults in primary care settings.

Hear answer to questions such as:

When might potential RSV vaccines be available, and when might the Advisory Committee on Immunization Practices make recommendations on their use?
How will the vaccine roll out? Who would receive the vaccine first?
If approved, what will the RSV vaccination schedule be?
How can we overcome vaccine hesitancy?

Presenters

John J. Russell, MD, FAAFP
Clinical Professor of Family and Community Medicine
Sidney Kimmel College of Medicine
Thomas Jefferson University
Philadelphia, Pennsylvania
Chair, Department of Family and Community Medicine
Abington-Jefferson Health
Abington, Pennsylvania

Laura Hurley, MD, MPH
Associate Professor of Medicine
Division of General Internal Medicine
Department of Medicine
University of Colorado Anschutz Medical Campus
Aurora, Colorado
Primary Care Physician
Division of General Internal Medicine
Department of Medicine
Denver Health
Denver, Colorado

Pamela Rockwell, DO, FAAFP
Professor
Family Medicine
University of Michigan Medical School
Ann Arbor, Michigan

View the full program at:
https://bit.ly/3Wt87GI

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What Patients Want in HIV Treatment and Prevention: United Kingdom

support@deceraclinical.com (Marc Thompson, Tristan J. Barber MA MD FRCP) — Wed, 2 Nov 2022 20:30:00 +0000

In this episode, Marc Thompson and Tristan J. Barber, MA, MD, FRCP, discuss some of the barriers to genuinely patient-centered HIV care in the United Kingdom and offer calls to action for healthcare professionals for responding to patient preferences. They discuss barriers to HIV testing and effectively communicating the benefits of testing to disparate communities. They also talk through the difficulties in maintaining patient engagement in HIV care and the value of using peer support workers in HIV clinics. You will then hear Marc and Dr Barber talk through treatment and prevention practices. They focus on the importance of messaging around U=U: that treatment can make a patient’s HIV undetectable, and therefore their HIV is untransmissible. They end with a discussion about changing treatment paradigms and how to keep patients informed and empowered—not overwhelmed—by those changes to help ensure lasting health outcomes.

Marc Thompson
Director, The Love Tank
Co-founder, Prepster
London, United Kingdom

Tristan J. Barber, MA, MD, FRCP
Honorary Associate Professor
Institute for Global Health
University College London
Consultant in HIV Medicine
Ian Charleson Day Centre
Royal Free Hospital
London, United Kingdom

Link to full program:
https://www.clinicaloptions.com/hiv/programs/2022/what-pts-want-hiv

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What Patients Want in HIV Treatment and Prevention: United States

support@deceraclinical.com (Samantha V Hill MD MPH, Deondre Moore) — Tue, 1 Nov 2022 20:30:00 +0000

In this episode, Deondre Moore and Samantha V. Hill, MD, MPH, discuss some of the barriers to genuinely patient-centered HIV care in the United States and offer calls to action for healthcare professionals for responding to patient preferences. They talk through some of the barriers that patients face, from struggling with unfamiliar medical terminology, to healthcare professional biases, to more structural problems like housing and food scarcity. They also discuss strategies that healthcare professionals can incorporate to provide more comprehensive, inclusive, collaborative HIV care.

Samantha V. Hill, MD, MPH
Assistant Professor
Division of Adolescent Medicine
Department of Pediatrics
The University of Alabama at Birmingham
Birmingham, Alabama

Deondre Moore
U.S. Partnerships and Community Engagement Manager
Prevention Access Campaign
Houston, Texas

Link to full program:
https://bit.ly/3fsWuij

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Addressing Barriers to PrEP Uptake Among Black Cisgender Women

support@deceraclinical.com (Samantha Strong PharmD BCACP AAHIVP CDCES) — Mon, 31 Oct 2022 20:30:00 +0000

In this episode, Samantha Strong, PharmD, BCACP, AAHIVP, CDCES, discusses closing the HIV pre-exposure prophylaxis (PrEP) gap for Black cisgender women, including:

Racial inequities in PrEP access
Addressing barriers to PrEP for cisgender women such as lack of education and awareness, low perceived risk of HIV, healthcare professional bias, and medical mistrust
Closing the PrEP gap through education, normalizing sexual health conversations, and decreasing stigma to empower women

Samantha Strong, PharmD, BCACP, AAHIVP, CDCES
Clinical Director of Pharmacy
Nevada Health Centers
Las Vegas, Nevada

See the full program at:
https://bit.ly/3WhbBvZ

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Addressing Barriers to PrEP Uptake Among Black MSM

support@deceraclinical.com (Latesha Elopre MD MSPH) — Thu, 27 Oct 2022 20:30:00 +0000

In this episode, Latesha Elopre, MD, MSPH, discusses closing the HIV pre-exposure prophylaxis (PrEP) gap for Black men who have sex with men (MSM), including:

Racial inequities in PrEP access
Considering strategies to address barriers to PrEP uptake and persistence among Black MSM
Considering individualized PrEP options
- On-demand oral emtricitabine/tenofovir disoproxil fumarate (2:1:1)
- Injectable cabotegravir
Empowering patients to take control of their PrEP care by providing choices for optimal adherence

Latesha Elopre, MD, MSPH
Associate Professor
Division of Infectious Diseases
Assistant Dean of Diversity and Inclusion
General Medical Education
University of Alabama at Birmingham
Birmingham, Alabama

For the full program, visit:
https://bit.ly/3VGrN9L

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London Perspective: Comorbidity and Adherence Considerations in Older Patients With HBV

support@deceraclinical.com (Graham R. Foster FRCP PhD) — Thu, 27 Oct 2022 20:30:00 +0000

When it comes to managing older adults with hepatitis B virus (HBV), what comorbidity, comedication, and adherence issues should be considered?

Listen as Graham R. Foster, FRCP, PhD, discusses these considerations and more for strategizing the monitoring and treatment of older adults with HBV.

Presenter:

Graham R. Foster, FRCP, PhD
Professor of Hepatology
The Liver Unit
Consultant Hepatologist
Queen Mary University of London
London, United Kingdom

Link to full program:
https://bit.ly/3fg9fwB

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Switching ART in a Virologically Suppressed Person With Suspected Underlying Resistance

support@deceraclinical.com (Timothy Wilkin MD MPH) — Thu, 20 Oct 2022 20:30:00 +0000

In this episode, Timothy J. Wilkin, MD, MPH, provides a case-based overview of switching antiretroviral therapy in a patient with viral suppression on their current regimen who has a history of virologic failure with drug-resistance mutations. Key findings from 2 relevant studies—the SWITCHMRK trial and Study 380-4030—are reviewed. The case discussion also highlights several other challenges that can be encountered in the switch setting, including incomplete immune recovery, comorbidities, and gastrointestinal intolerability of some antiretroviral drugs.

Presenter:

Timothy J. Wilkin, MD, MPH
Professor Medicine
Division of Infectious Diseases
Weill Medical College of Cornell University
New York, New York

Content based on an online CME/CE program supported by an independent educational grant from ViiV Healthcare.

Link to full program:
https://bit.ly/3VIsDTg

Follow along with the slides at
https://bit.ly/3DdP3F6

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Answering the Questions on Switching ART With Virologic Suppression

support@deceraclinical.com (Tristan J. Barber MA MD FRCP, Darcy Wooten MD) — Wed, 19 Oct 2022 20:30:00 +0000

In this episode, Tristan J. Barber, MA, MD, FRCP, and Darcy Wooten, MD, discuss switching ART with virologic suppression, including:

Switching with prior or unknown resistance
- Data on switching to BIC/FTC/TAF with a preexisting M184V/I mutation from a pooled analysis of 6 phase III studies
- The impact of baseline resistance on outcomes following a switch to BIC/FTC/TAF in Black PWH from the BRAAVE 2020 study
- A post hoc analysis of the SALSA study of DTG/3TC outcomes at Week 48 by baseline resistance
- Data from the SOLAR 3D study on switching to DTG/3TC from a 3- or 4-drug ART regimen with a history of M184V
- A retrospective analysis of switching to DTG/3TC with archived M184V/I from the French Dat’AIDS Cohort
Switching to long-acting ART
- Guidance on candidates for LA CAB + RPV
- Data on risk factors for virologic failure with LA CAB + RPV
Considering an ART switch after weight gain
- Data on weight gain after ART initiation by ARV class and drug
- Mean change in weight by sex at Week 96 in the ADVANCE study
- DHHS guideline recommendations regarding weight gain with ART

Darcy Wooten, MD
Associate Professor of Medicine
Division of Infectious Diseases and Global Public Health
Department of Medicine
University of California, San Diego
San Diego, California

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All Eyes on ExPEC: A Major Driver of Invasive Disease and Antimicrobial Resistance

Tue, 18 Oct 2022 20:30:00 +0000

In this episode, Lilian Abbo, MD, FIDSA; Julie Ann Justo, PharmD, MS; and David van Duin, MD, PhD, FIDSA, FAST, discuss key concepts about extraintestinal pathogenic Escherichia coli, including:

Diverse strains and virulence factors associated with invasive disease
Antimicrobial resistance profiles seen in clinical practice
Various disease manifestations
Prevalence and burden of invasive infections
Populations at risk
Risk factors for multidrug-resistant strains
Emerging vaccine technologies
Active clinical trials
Benefits of vaccines and the challenges associated with development
Importance of antimicrobial stewardship and potential role of vaccines to reduce antimicrobial resistance

Program Director:
Lilian Abbo, MD, FIDSA
Associate Chief Medical Officer in Infectious Diseases
Jackson Health System
Professor of Infectious Diseases
Department of Medicine & Miami Transplant Institute
University of Miami Miller School of Medicine
Miami, Florida

Faculty:
Julie Ann Justo, PharmD, MS
Clinical Associate Professor
Department of Clinical Pharmacy and Outcomes Sciences
University of South Carolina College of Pharmacy
Infectious Diseases Clinical Pharmacy Specialist
Department of Pharmacy
Prisma Health Richland Hospital
Columbia, South Carolina

David Van Duin, MD, PhD, FIDSA, FAST
Professor of Medicine
Director, Immunocompromised Host Infectious Diseases Program
Division of Infectious Diseases
University of North Carolina
Chapel Hill, North Carolina

Content based on a CME program supported by an educational grant from Janssen Therapeutics.

Follow along with a downloadable slideset at:
https://bit.ly/3eG29Bn

Link to full program:
https://bit.ly/3eFHfCl

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Meningococcal Disease: A Deadly, Unpredictable but Preventable Disease

support@deceraclinical.com (Gary S. Marshall MD) — Wed, 12 Oct 2022 20:45:00 +0000

In this podcast, Gary S. Marshall, MD, summarizes the burden of meningococcal disease and the importance of immunization, including:

The unpredictability and severity of meningococcal disease
Differences between meningococcal serogroups and available vaccines
Current meningococcal vaccine recommendations, distinguishing between routine vs shared clinical decision-making recommendations
Vaccine recommendations in high-risk populations
Use of immunization platforms to help complete age-appropriate vaccines, including the MenACWY and MenB vaccine, in adolescents and young adults

Faculty:

Gary S. Marshall, MD
Professor of Pediatrics
Division of Pediatric Infectious Diseases
University of Louisville School of Medicine
Louisville, Kentucky

Link to full program:
https://bit.ly/3T0GLG2

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Empowering Patients to “Age Healthy” With HIV

support@deceraclinical.com (Cristina Mussini MD) — Wed, 12 Oct 2022 20:30:00 +0000

In this episode, Cristina Mussini, MD, shares her approach to caring for aging patients with HIV. This includes not just focusing on their HIV, but their over well-being, such as:

Maintaining a healthy weight, eating healthy and staying mobile
Overcoming the obstacle of stigma from society and self-stigma
Empowering patients to care for themselves
In women who are often caregivers most of their life:
- Encouraging self-care
- Staying up to date with preventive care such as cancer screenings (eg, mammography, annual Pap smear, and colonoscopy)
Teaching patients to love themselves
Making sure the patient knows you truly care for them

Faculty:

Link to full program:
https://bit.ly/3KkF4iZ

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Managing Older Patients With Chronic HBV: A Global Perspective

support@deceraclinical.com (Nancy Reau MD) — Mon, 10 Oct 2022 20:30:00 +0000

How do we define “older” in our older patients living with hepatitis B virus (HBV)? What monitoring and treatment options should be considered for these older patients with chronic HBV infection?

Listen as Nancy Reau, MD, discusses strategies and considerations for monitoring and treating older adults with HBV, illustrated with a patient case.

Presenter:

Nancy Reau, MD
Professor of Medicine
Chief, Section of Hepatology
Associate Director, Solid Organ Transplantation
Richard B. Capps Chair of Hepatology
Rush University Medical Center
Chicago, Illinois

Link to full program:
https://bit.ly/3T1UImw

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Weight Gain and Cardiometabolic Toxicities in Patients With HIV

support@deceraclinical.com (Priscilla Y. Hsue MD, Jens D. Lundgren MD DMSc) — Tue, 4 Oct 2022 20:30:00 +0000

In this episode, listen to Priscilla Y. Hsue, MD, and Jens D. Lundgren MD, DMSc, discuss the latest data about ARV-related weight gain and cardiometabolic toxicities in PWH. Hear faculty:

Review risk factors associated with significant weight gain
Consider possible implications of weight gain and cardiometabolic toxicities
Share their approaches to ARV-related weight gain and/or cardiometabolic toxicities

Faculty:

Priscilla Y. Hsue, MD
Professor of Medicine
University of California at San Francisco
San Francisco General Hospital
San Francisco, California

Link to full program:
https://bit.ly/3PM3nYe

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Key HIV Studies Influencing My Practice Following AIDS 2022—Audio Redcap

support@deceraclinical.com (Chloe Orkin MBChB FRCP MD) — Tue, 4 Oct 2022 20:30:00 +0000

In this episode, Chloe Orkin, MBChB, FRCP, MD, discusses new HIV data from AIDS 2022, including:

Prevention strategies
Oral therapies
LA therapies
Cure
COVID-19 in PWH

Faculty
Chloe Orkin, MBChB, FRCP, MD
Professor of HIV
Queen Mary, University of London
Consultant Physician
Lead for HIV Research
Barts Health NHS Trust
The Royal London Hospital
London, United Kingdom

Follow along with the slides at
bit.ly/3SLuhBq

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Switching ART in the Context of Pregnancy

support@deceraclinical.com (Roger Bedimo MD MS FACP) — Mon, 3 Oct 2022 20:45:00 +0000

In this episode, Roger Bedimo, MD, MS, FACP, discusses key considerations for switching ART in virologically suppressed patients who are pregnant or trying to conceive. His discussion includes:

DHHS Perinatal Guideline recommendations
French Perinatal Cohort study on the implications of viral suppression when changing ART in the first trimester of pregnancy
IMPAACT 2010 Update on the safety and efficacy of DTG vs EFV and TDF vs TAF in pregnancy
DolPHIN-2 study of virological suppression with DTG- vs EFV-based ART started in late pregnancy

Presenter:

Roger Bedimo, MD, MS, FACP
Professor of Medicine
Division of Infectious Diseases
University of Texas Southwestern Medical Center
Section Chief
Division of Infectious Diseases
Department of Internal Medicine
VA North Texas Health Care System
Dallas, Texas

Content based on an online CME program supported by an independent educational grant from ViiV Healthcare.

Link to full program:
https://bit.ly/3UYTF8Q

Follow along with the slides at
https://bit.ly/3CqhrmU

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My Lived Experience as a Woman Aging With HIV

support@deceraclinical.com (Melanie Reese) — Thu, 29 Sep 2022 16:55:00 +0000

In this podcast, Melanie Reese, a woman aging with HIV, shares her perspectives on the added challenges faced by older women with HIV—an underserved, underresourced, and underresearched group—and talks about potential solutions that should be considered, such as:

Listen and prioritize concerns brought to you by older women with HIV to improve trust in you and the medical profession
Promote self-advocacy for women to improve their interactions with healthcare professionals, such as opening the dialogue about sexual health
Support mental health by ensuring a baseline neurologic exam to monitor for any cognitive decline
Emphasize the importance of self-care and prioritizing oneself
Address psychosocial issues by finding ways for patients to connect with others
Advocate to change policies, standards of care, and laws that govern all places that care for those who are aging and need assistance in care

Faculty
Melanie Reese
Subject Matter Expert, HIV Aging
Technical Expert Panel
Health Resources and Services Administration
HIV/AIDS Bureau
Baltimore, Maryland

Link to full program:
https://bit.ly/3KkF4iZ

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Finding Our Voices: Older Women With HIV in Resource-Limited Settings

support@deceraclinical.com (Dorothy Onyango) — Tue, 20 Sep 2022 20:25:00 +0000

In this episode, listen to Dorothy Onyango, patient and patient activist, share her views on the many barriers encountered by aging patients with HIV living in resource-limited settings and the need to work on solutions to overcome such barriers, including:

The major burden of poverty affecting access to care/medications, healthcare services (eg, treatment for noncommunicable diseases, home-based care), and social support
The added social obstructions to HIV care for older women (eg, sexual reproductive health rights)
Potential solutions to support the aging population with HIV to encourage good health and wellness such as:
- Self-advocacy to provide a voice for patients, especially women
- A comprehensive public health response
- Policy changes, including a budget line in the national budget, to ensure the rights of older people
- AIDS-friendly prevention initiatives (eg, affordable/accessible condoms)
- Income-generating activities to help older patients with HIV become economically sound

Faculty:

Dorothy Onyango
Chief Executive Officer
Women Fighting AIDS in Kenya
Founding Member, International Community of Women Living With HIV
Former Chair, Pan African Women’s Coalition
Former Board Member, Kenya National AIDS Council
Nairobi, Kenya

Link to full program:
https://bit.ly/3yIkntc

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Long-Acting Cabotegravir for HIV Prevention

Thu, 8 Sep 2022 20:55:00 +0000

In this episode, an international expert panel shares their thoughts on key considerations for incorporating long-acting cabotegravir as an additional HIV pre-exposure prophylaxis option for appropriate individuals at high risk of acquiring HIV infection.

Topics include anticipated patient interest in this new paradigm, the role of the oral lead-in phase, new guideline recommendations for monitoring during PrEP, patient care and follow-up after PrEP discontinuation, and remaining unanswered questions.

Other episodes in this 4-part series cover additional aspects of long-acting antiretrovirals for HIV treatment and prevention, including key steps for switching patients to long-acting injectable cabotegravir plus rilpivirine for HIV treatment, such as selecting the most appropriate patients, introducing patients to the long-acting option, and preparing patients for what to expect from long-acting treatment in terms of efficacy, visit timing, and the injection experience; key considerations at the operational level for incorporating long-acting injectable ART into the HIV treatment armamentarium; and what is still needed in long-acting HIV care to further address patient needs and inequities across subgroups.

Presenters:

Babafemi Taiwo, MBBS
Gene Stollerman Professor of Medicine
Chief, Division of Infectious Diseases
Northwestern University
Feinberg School of Medicine
Chicago, Illinois

Content based on an online CME/CE program supported by an independent educational grant from ViiV Healthcare.

Link to full program:
https://bit.ly/3P3uPBc

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Piecing the Puzzle Together: Addressing Medical Challenges in Older PWH

support@deceraclinical.com (Jonathan Appelbaum MD FACP AAHIVS) — Thu, 25 Aug 2022 16:00:00 +0000

In this podcast, Jonathan Appelbaum, MD, FACP, AAHIVS, summarizes the many medical challenges faced by aging people with HIV, including:

Underrepresentation of older patients in medical research
Consequences of early experiences in the epidemic such as late HIV diagnosis and low CD4+ cell count nadir, incomplete or short-lived virologic suppression with early regimens, and toxicity associated with early antiretroviral agents
Added challenges of multimorbidity and psychosocial challenges, especially mental health issues, loneliness, and social isolation
The need to provide care for the aging HIV population using a holistic approach
Gaps in the current healthcare system in providing optimal care for aging people with HIV

Faculty:

Jonathan Appelbaum, MD, FACP, AAHIVS
Laurie L. Dozier Jr, MD, Education Director
Professor of Internal Medicine
Chair, Department of Clinical Sciences
Florida State University College of Medicine
Tallahassee, Florida

Link to full program:
https://bit.ly/3KkF4iZ

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Ending the HIV Epidemic: Reaching the Undiagnosed

Wed, 24 Aug 2022 16:00:00 +0000

In this episode, Babafemi Taiwo, MBBS, discusses strategies for reaching people with HIV who are not yet diagnosed. His overview includes:

HIV diagnosis by global region
Disparities in serostatus awareness
Patient perspective on importance of HIV testing
Barriers to HIV diagnosis
Complications from late HIV diagnosis
Strategies to improve rates of HIV testing

Presenter:

Babafemi Taiwo, MBBS
Gene Stollerman Professor of Medicine
Chief, Division of Infectious Diseases
Northwestern University
Feinberg School of Medicine
Chicago, Illinois

Panelists:

Linda-Gail Bekker, MBChB, DTM&H, DCH, FCP(SA), PhD
Director
Desmond Tutu HIV Centre
Past President
International AIDS Society
Faculty of Health Sciences
University of Cape Town
Cape Town, South Africa

Nagalingeswaran Kumarasamy, MBBS, FRCP, PhD
Chief and Director
VHS Infectious Diseases Medical Centre
Director, Chennai Antiviral Research and Treatment (CART) Clinical Research Site
Voluntary Health Services
Chennai, India

Content based on an online CME program supported by an independent educational grant from Gilead Sciences.

Follow along with the slides:
https://bit.ly/3PJRthD

Link to full program:
https://bit.ly/3AE2AV1

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Ending the HIV Epidemic: Keys to Successful Treatment Initiation

Wed, 24 Aug 2022 16:00:00 +0000

In this episode, Chloe Orkin, MBChB, FRCP, MD, discusses strategies for successful antiretroviral therapy (ART) initiation. Her overview includes:

Recommendations for rapid ART
First-line ART regimens for treatment-naive people with HIV
IMEA 055 FAST study
STAT study
DIAMOND study
Antiretroviral resistance mutations
Patient perspectives on the importance of rapid ART initiation

Presenter:

Panelists:

Babafemi Taiwo, MBBS
Gene Stollerman Professor of Medicine
Chief, Division of Infectious Diseases
Northwestern University
Feinberg School of Medicine
Chicago, Illinois

Content based on an online CME program supported by an independent educational grant from Gilead Sciences.

Follow along with the slides:
https://bit.ly/3dSNoum

Link to full program:
https://bit.ly/3AE2AV1

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Ending the HIV Epidemic: Care Pathways After HIV Testing

Wed, 24 Aug 2022 16:00:00 +0000

In this episode, Nagalingeswaran Kumarasamy, MBBS, FRCP, PhD, discusses the importance of linking people to care after a positive HIV diagnosis. His overview includes:

HIV care continuum
Factors that delay linkage to care
Organized strategies to improve linkage to care for people with HIV
Interventions that may improve linkage to care for people with HIV
Patient perspective on how to engage patients in their HIV care

Presenter:

Panelists:

Content based on an online CME program supported by an independent educational grant from Gilead Sciences.

Follow along with the slides:
https://bit.ly/3PJ4iJ8

Link to full program:
https://bit.ly/3AE2AV1

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Safety Considerations for HIV Treatments During Pregnancy

Tue, 23 Aug 2022 20:00:00 +0000

In this episode, hear Dr. Jean Rene Anderson and Dr. William Short discuss special factors to consider when selecting HIV treatments during pregnancy, including:

Key elements involved in evaluating ARV medications during pregnancy (eg, efficacy, pharmacokinetic, and safety data)
Approach to optimizing ART regimens prior to and during pregnancy

Faculty:

Jean Rene Anderson, MD
Professor
Department of Gynecology and Obstetrics
Johns Hopkins University
Director, Johns Hopkins HIV Women's Health Program
Johns Hopkins Medical Institutions
Baltimore, Maryland

Link to full program:
https://bit.ly/3PM3nYe

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Linkage to Care for Patients With HDV

support@deceraclinical.com (Decera Clinical Education) — Wed, 3 Aug 2022 01:15:00 +0000

You can think of the “D” in HDV as standing for difficult, disadvantaged, and dangerous. Hepatitis delta virus (HDV) is difficult to diagnose, is often diagnosed in disadvantaged patient populations, and leads to dangerous sequelae.

Listen as Dr. Kosh Agarwal and Dr. Graham R. Foster and discuss challenges and opportunities for linking patients to care after a positive test for HDV.

Presenters:

Kosh Agarwal, MD
Consultant Hepatologist and Transplant Physician
Institute of Liver Studies
King's College Hospital NHS Foundation Trust
London, United Kingdom

Graham R. Foster, FRCP, PhD
Professor of Hepatology
The Liver Unit
Consultant Hepatologist
Queen Mary University of London
London, United Kingdom

Link to full program:
https://bit.ly/3tlxa0H

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Implementing Long-Acting Cabotegravir Plus Rilpivirine for HIV Treatment: System-Level Considerations

Tue, 2 Aug 2022 20:35:00 +0000

In this episode, an international expert panel shares their thoughts on key considerations at the operational level for incorporating long-acting injectable antiretroviral therapy into the HIV treatment armamentarium. Topics include the duration of injection appointments in real-world settings, managing additional patient volume/workload (particularly the key role of nurses), and preventing and addressing planned and unplanned missed doses. Other episodes in this 4-part series cover additional aspects of long-acting antiretrovirals for HIV treatment and prevention, including:

Key steps for switching patients to long-acting injectable cabotegravir plus rilpivirine for HIV treatment, such as selecting the most appropriate patients, introducing patients to the long-acting option, and preparing patients for what to expect from long-acting treatment in terms of efficacy, visit timing, and the injection experience
Long-acting HIV pre-exposure prophylaxis
What is still needed in long-acting HIV care to further address patient needs and inequities across subgroups

Presenters:

Babafemi Taiwo, MBBS
Gene Stollerman Professor of Medicine
Chief, Division of Infectious Diseases
Northwestern University
Feinberg School of Medicine
Chicago, Illinois

Yvonne Gilleece, MB, BCh, BAO
Honorary Clinical Professor in HIV Medicine and Sexual Health
Department of Global Health & HIV
Brighton & Sussex Medical School
Consultant in HIV Medicine and Sexual Health
HIV Department
University Hospitals Sussex NHS Foundation Trust
Brighton, United Kingdom

Cristina Mussini, MD
Head of Department of Infectious Diseases and Tropical Medicine
Full Professor of Infectious Diseases
Infectious Diseases Clinics, University Hospital
University of Modena and Reggio Emilia
Modena, Italy

Content based on an online CME/CE program supported by an independent educational grant from ViiV Healthcare.

Link to full program:
https://bit.ly/3P3uPBc

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Switching to Long-Acting Cabotegravir Plus Rilpirivine for HIV Treatment: Assessing Candidacy and Patient Counseling

Thu, 14 Jul 2022 17:00:00 +0000

In this episode, an international expert panel shares their thoughts on key steps for switching patients to long-acting injectable cabotegravir plus rilpivirine for HIV treatment, including selecting the most appropriate patients, introducing patients to the long-acting option, and preparing patients for what to expect from long-acting treatment in terms of efficacy, visit timing, and the injection experience. Subsequent episodes in this 4-part series will cover additional aspects of long-acting antiretrovirals for HIV treatment and prevention, including operational planning, clinic impact, and handling missed doses with long-acting antiretroviral therapy for treatment; long-acting HIV pre-exposure prophylaxis; and what is still needed in long-acting HIV care to further address patient needs and inequities across subgroups.

Presenters:

Babafemi Taiwo, MBBS
Gene Stollerman Professor of Medicine
Chief, Division of Infectious Diseases
Northwestern University
Feinberg School of Medicine
Chicago, Illinois

Yvonne Gilleece, MB, BCh, BAO
Honorary Clinical Professor in HIV Medicine and Sexual Health
Department of Global Health & HIV
Brighton & Sussex Medical School
Consultant in HIV Medicine and Sexual Health
HIV Department
University Hospitals Sussex NHS Foundation Trust
Brighton, United Kingdom

Content based on an online CME/CE program supported by an independent educational grant from ViiV Healthcare.

Link to full program:
https://bit.ly/3P3uPBc

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First Cohort With HIV: Paving the Path for the Future

support@deceraclinical.com (Marc Thompson) — Wed, 6 Jul 2022 20:05:00 +0000

In this episode, hear HIV activist Marc Thompson share his perspectives on aging with HIV including:

His early experiences after receiving his diagnosis
Persisting issues of the HIV epidemic including stigma and discrimination
Changes in healthcare with the advent of HIV treatment
Added issues of aging with HIV like polypharmacy, multimorbidity, and mental health concerns (eg, loneliness, social isolation)
Actions needed to improve the path for the future: addressing opportunities to expand research, improve collaboration between HIV and other healthcare professionals and gain wisdom and knowledge from others aging with HIV

Presenter:

Marc Thompson
Director, The Love Tank

Link to full program:
https://bit.ly/3yIkntc

You can also join Marc Thompson and a panel of patient advocates and healthcare professionals in person or in a live simulcast as they discuss healthy aging with HIV at our live symposium at AIDS 2022 in Montreal, Quebec, Canada. They will discuss the challenges faced by older people with HIV, including medical and nonmedical issues, and specific challenges faced by subgroups of older patients such as women and patients in resource-limited settings.

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Key Viral Hepatitis Studies Influencing My Practice Following EASL 2022—Audio Recap

support@deceraclinical.com (Stefan Zeuzem MD) — Wed, 6 Jul 2022 20:00:00 +0000

In this episode, Stefan Zeuzem, MD, discusses new viral hepatitis data from EASL 2022, including:

Novel HBV therapeutics, including the REEF-2, B-Clear, and SAVE-1 studies
HBV cure from the Everest Project in China
HDV therapeutics from MYR301 and a study of bulevirtide in patients with cirrhosis and portal hypertension
HCV retreatment in patients with prior direct-acting antiviral therapy failure

Presenter:

Stefan Zeuzem, MD
Professor of Medicine
Chief, Department of Medicine I
JW Goethe University Hospital
Frankfurt, Germany

Follow along with the downloadable slideset at:
https://bit.ly/3yJAruD

Link to full program:
https://bit.ly/3AjCNBC

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Advancements in Viral Hepatitis From EASL 2022

support@deceraclinical.com (Nancy Reau MD) — Tue, 5 Jul 2022 19:45:00 +0000

In this episode, Nancy Reau, MD, discusses new viral hepatitis data from EASL 2022, including:

Novel therapeutics for HBV
Therapeutic vaccination for HBV
Emerging treatment options for HDV
HCV care cascade
HCC monitoring after HCV cure

Presenter:

Follow along with the downloadable slideset at:
https://bit.ly/3yJAruD

Link to full program:
https://bit.ly/3IeUapm

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Defining and Striving for HBV Cure: What’s in the Pipeline

support@deceraclinical.com (Carla Coffin MD MSc) — Thu, 30 Jun 2022 16:05:00 +0000

In this episode, Carla S. Coffin, MD, MSc, shares her thoughts on the different investigational approaches under evaluation for their potential to achieve HBV cure, including entry inhibitors, capsid inhibitors, siRNAs, immune modulators, TLR agonists, therapeutic vaccines, and checkpoint inhibitors.

Presenter:

Carla S. Coffin, MD, MSc
Professor of Medicine
Division of Gastroenterology and Hepatology
Department of Medicine
University of Calgary
Medical Director of Calgary Liver Unit
Division of Gastroenterology and Hepatology
Department of Medicine
Foothills Medical Centre
Calgary, Alberta, Canada

Content based on an online CME program supported by independent educational grants from AbbVie and Gilead Sciences, Inc. and developed in collaboration with the American Liver Foundation.

Link to full program:
https://bit.ly/3OGHvOv

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My Perspective: Living With HIV Is Life Changing but Not Life Limiting

support@deceraclinical.com (Yvette Raphael) — Tue, 21 Jun 2022 19:20:00 +0000

In this episode, Yvette Raphael provides her perspectives and advice as an individual living with HIV in South Africa for more than 20 years. She shares her experiences and ideas for how to improve processes related to HIV diagnosis, care linkage, and treatment.

Presenter:

Yvette Raphael

Content based on an online CME program supported by an independent educational grant from Gilead Sciences, Inc.

Link to full program:
https://bit.ly/3tmgozy

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When Patients With Chronic HBV Infection Do Not Meet Indications for Immediate Treatment: The Critical Role of Ongoing Monitoring

support@deceraclinical.com (Pietro Lampertico MD PhD) — Thu, 26 May 2022 18:00:00 +0000

In this episode, Pietro Lampertico, MD, PhD, discusses what to do when treatment for hepatitis B virus (HBV) infection is not indicated, covering topics such as:

The different phases of chronic HBV infection
Which patients in different phases require immediate HBV treatment and which can be monitored without therapy
The critical importance of ongoing monitoring for patients who do not meet indications for immediate therapy
The tests and frequency that should be used for monitoring patients not receiving HBV treatment

Presenter:

Pietro Lampertico, MD, PhD
Professor of Gastroenterology
Director, Division of Gastroenterology and Hepatology
IRCCS Ca Granda Policlinico Hospital
University of Milan
Milan, Italy

Content based on an online CME program supported by independent educational grants from AbbVie and Gilead Sciences, Inc. and developed in collaboration with the American Liver Foundation.

Link to full program:
https://bit.ly/3OGHvOv

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Key Decisions in HIV Care: Postexposure Prophylaxis

support@deceraclinical.com (Michelle Collins-Ogle MD FAAP FPIDS AAHIVS) — Thu, 26 May 2022 17:35:00 +0000

In this episode, Michelle D. Collins-Ogle, MD, FAAP, FPIDS, AAHIVS, explores the data and recommendations for HIV postexposure prophylaxis (PEP).

Listen as she gives perspectives on:

The CDC algorithm for evaluation and treatment of
potential HIV exposures
The CDC guideline preferred and alternative PEP antiretroviral therapy regimens
Data for the use of the single-tablet regimen bictegravir/emtricitabine/tenofovir alafenamide for PEP
Recommended laboratory monitoring with PEP
The initiation of pre-exposure prophylaxis following a course of PEP, when appropriate

Presenter:

Michelle D. Collins-Ogle, MD, FAAP, FPIDS, AAHIVS
Assistant Professor of Pediatrics
Division of Pediatric Infectious Diseases
Pediatric and Adolescent HIV
Children’s Hospital at Montefiore
Pediatric Hospital of Albert Einstein
College of Medicine
Bronx, New York

Follow along with the slides at:
https://bit.ly/3NBVXWN

See the entire program at:
https://bit.ly/3fOl0XX

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Key Decisions in HIV Care: Choosing ART for Pediatric Patients

Wed, 25 May 2022 20:40:00 +0000

In this episode, Michelle D. Collins-Ogle, MD, FAAP, FPIDS, AAHIVS, explores key considerations for choosing antiretroviral therapy (ART) for pediatric patients.

Listen as she gives perspectives on:

Department of Health and Human Services (DHHS) guideline recommendations for infants at risk for perinatal HIV transmission
DHHS guideline–recommended ART regimens for children
The ODYSSEY A and B studies evaluating dolutegravir-based ART in children and adolescents
Data for the use of the fixed-dose combination bictegravir/emtricitabine/tenofovir alafenamide in children and adolescents
Key ART and management considerations for adolescents and young adults with HIV

Presenter:

Follow along with the slides at:
https://bit.ly/3wMur29

Link to full program:
https://bit.ly/3fOl0XX

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Key Decisions in HIV Care: Treatment Considerations for Transgender PWH

Wed, 25 May 2022 20:40:00 +0000

In this episode, Michelle D. Collins-Ogle, MD, FAAP, FPIDS, AAHIVS, explores key considerations for transgender people with HIV (PWH).

Listen as she gives perspectives on:

Department of Health and Human Services (DHHS) guideline recommendations for transgender PWH
Providing HIV care within a gender-affirmative care model, including discussion of strategies, barriers, and facilitators
Gender-affirmative hormone therapy options
Drug–drug interaction potential between gender-affirmative hormone therapy and antiretroviral therapy
Recommended laboratory monitoring while receiving gender-affirming hormone therapy
The cascade of care for transgender PWH and barriers to engagement and retention in care

Presenter:

Follow along with the slides at:
https://bit.ly/3wOdKVo

Link to full program:
https://bit.ly/3fOl0XX

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COVID-19: Outpatient Therapeutic Updates

support@deceraclinical.com (Sharon R. Lewin AO FRACP PhD FAHMS, Sharon Lewin) — Tue, 24 May 2022 20:00:00 +0000

In this episode, Sharon R. Lewin, AO, FRACP, PhD, FAHMS, discusses:

Principles for antiviral agent use in nonhospitalized patients

Preferred and alternative treatment options
Treatment prioritization when there are logistical or supply constraints

Outpatient remdesivir use

PINETREE data (adult patients)
CARAVAN data (pediatric patients)
FDA approval and treatment candidacy

Therapeutic updates

Ivermectin and the TOGETHER study
Monoclonal antibody use during current omicron era

Presenter:

Sharon R. Lewin, AO, FRACP, PhD, FAHMSZ
Director, The Peter Doherty Institute for Infection and Immunity
Professor of Infectious Diseases
University of Melbourne
Consultant Infectious Diseases Physician
Alfred Hospital and Royal Melbourne Hospital
Melbourne, Australia

Review the downloadable slideset at:
https://bit.ly/3FXc90w

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RSV in Older Adults: Immunology and Vaccine Development

support@deceraclinical.com (Dexter Wiseman MD) — Thu, 5 May 2022 20:40:00 +0000

In this episode, Dexter James Wiseman, MD, discusses immunology and RSV vaccine development for older adults, including:

Need for a vaccine
Economic burden of RSV
Reasons for poor outcomes in older adults
Investigational vaccines

Presenter:

Dexter James Wiseman, MD
Clinical Research Fellow
NHLI
Imperial College
Physician
Respiratory Medicine
Royal Brompton Hospital
London, United Kingdom

Review the downloadable slideset and the full program at:
https://bit.ly/3ydC8Ri

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Adult HBV Vaccination: Current Vaccines and Vaccination Strategies

support@deceraclinical.com (Robert G. Gish MD) — Thu, 5 May 2022 20:30:00 +0000

In this episode, listen as Robert G. Gish, MD, discusses key information on comparing current HBV vaccine formulations, and learn the best immunization practices for routine vaccination, including in special situations.

Presenter:

Robert G. Gish, MD
Professor of Medicine
Loma Linda University
Loma Linda, California
Adjunct Professor of Medicine
Nevada School of Medicine
Las Vega, Nevada
Clinical Professor
University of Nevada Reno
School of Medicine
Reno, Nevada
Clinical Professor
University of California Skaggs School of Pharmacy and Pharmaceutical Sciences
San Diego, California
Medical Director
Hepatitis B Foundation
Washington, DC

Review the downloadable slidesets at:
https://bit.ly/3LJPPLz

Link to full program:
https://bit.ly/3OZ50Ta

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RSV in Older Adults: Identification and Impact

support@deceraclinical.com (Dexter James Wiseman MD) — Thu, 5 May 2022 20:30:00 +0000

In this episode, Dexter James Wiseman, MD, discusses the impact and diagnosis of RSV in older adults, including:

Risk factors for poor outcomes
RSV vs influenza outcomes
RSV symptoms
RSV diagnostics

Presenter:

Dexter James Wiseman, MD
Clinical Research Fellow
NHLI
Imperial College
Physician
Respiratory Medicine
Royal Brompton Hospital
London, United Kingdom

Review the downloadable slideset and the full program at:
https://bit.ly/3ydC8Ri

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RSV in Older Adults: Epidemiology and Risk Factors

support@deceraclinical.com (Dexter James Wiseman MD) — Thu, 5 May 2022 20:30:00 +0000

In this episode, Dexter James Wiseman, MD, discusses the epidemiology and risk factors for RSV in older adults, including:

Overview
Disease burden based on age
Seasonality
Impact in care facilities
Effects of the COVID-19 pandemic

Presenter:

Dexter James Wiseman, MD
Clinical Research Fellow
NHLI
Imperial College
Physician
Respiratory Medicine
Royal Brompton Hospital
London, United Kingdom

Review the downloadable slideset and the full program at:
https://bit.ly/3ydC8Ri

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Adult HBV Vaccination: Identifying Individuals at Risk for Reduced Seroprotection

support@deceraclinical.com (Robert Gish MD) — Thu, 5 May 2022 20:10:00 +0000

In this episode, learn about the importance of identifying adults at risk for reduced hepatitis B virus (HBV) seroprotection and applying current HBV vaccine recommendations in special populations. Listen as Robert G. Gish, MD, discusses key information on the identification and evaluation of patients who have chronic health conditions and therefore may be at risk for nonresponse to available vaccines.

Presenter:

Robert G. Gish, MD
Professor of Medicine
Loma Linda University
Loma Linda, California
Adjunct Professor of Medicine
Nevada School of Medicine
Las Vega, Nevada
Clinical Professor
University of Nevada Reno
School of Medicine
Reno, Nevada
Clinical Professor
University of California Skaggs School of
Pharmacy and Pharmaceutical Sciences
San Diego, California
Medical Director
Hepatitis B Foundation
Washington, DC

Review the downloadable slidesets at:
https://bit.ly/3KPiJZz

Link to full program:
https://bit.ly/3OZ50Ta

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Adult HBV Vaccination: Overcoming Gaps to Lessen the Burden and Impact of HBV

support@deceraclinical.com (Robert G Gish MD) — Thu, 5 May 2022 20:00:00 +0000

In this episode, learn about the importance of hepatitis B virus (HBV) vaccination in adults. Listen as Robert G. Gish, MD, discusses key data on the burden and impact of HBV infection, and strategies to overcome barriers to HBV vaccination.

Robert G. Gish, MD
Professor of Medicine
Loma Linda University
Loma Linda, California
Adjunct Professor of Medicine
Nevada School of Medicine
Las Vega, Nevada
Clinical Professor
University of Nevada Reno
School of Medicine
Reno, Nevada
Clinical Professor
University of California Skaggs School of
Pharmacy and Pharmaceutical Sciences
San Diego, California
Medical Director
Hepatitis B Foundation
Washington, DC

Review the downloadable slidesets at:
https://bit.ly/3l1ZD8h

Link to full program:
https://bit.ly/3LMZn8E

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Increasing Awareness of Hepatitis Delta

support@deceraclinical.com (Grace LH Wong MD, Ming Lung Yu MD PhD) — Tue, 3 May 2022 21:00:00 +0000

Hepatitis delta virus (HDV) is the most severe form of viral hepatitis, yet many patients go undiagnosed. Increasing HDV awareness is an important step to correct this and ensure that at-risk patients receive screening and then treatment and monitoring following a positive test. Hear Grace LH Wong, MD, and Ming-Lung Yu, MD, PhD, discuss a call to action to increase healthcare professional and patient awareness of HDV.

Presenters:

Grace LH Wong, MD
Professor
Director, Medical Data Analytics Centre (MDAC)
Deputy Director, Center for Liver Health
Assistant Dean (Learning Experience), Faculty of Medicine
The Chinese University of Hong Kong
Honorary Consultant
Division of Gastroenterology and Hepatology
Department of Medicine and Therapeutics
Prince of Wales Hospital
Hong Kong

Ming-Lung Yu, MD, PhD
Chair Professor
Hepatobiliary Division
Department of Internal Medicine and Hepatitis Center
Kaohsiung Medical University
Visiting Staff
Hepatobiliary Division
Department of Internal Medicine
Kaohsiung Medical University Hospital
Kaohsiung City, Taiwan

Link to full program:
https://bit.ly/3tlxa0H

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Why Everyone Should Be Screened for HCV and Treated If They Have It: Conversations Between Patient and Physician

support@deceraclinical.com (Shelley Rossell, Norah Terrault MD MPH) — Tue, 3 May 2022 18:00:00 +0000

In this episode, Norah Terrault, MD, MPH, and a patient who has been cured of hepatitis C virus (HCV) infection discuss the importance of universal HCV testing for all adults, as well as the ease of curative therapies and the benefits of living with improved liver function post cure.

This insightful discussion underscores how perceptions around HCV transmission risks and lack of symptoms serve as barriers to adequate screening and diagnosis, preventing curative treatment for many people with undiagnosed disease. The conversation also highlights the critical role of patient education and self-advocacy related to HCV infection, including what patients need to know and expect following cure.

Presenters:

Shelley Rossell

Norah Terrault, MD, MPH
Professor of Medicine
Chief of Gastrointestinal and Liver Diseases
University of Southern California
Los Angeles, California

Content is based on an online CME program supported by independent educational grants from AbbVie and Gilead Sciences, Inc. and developed in collaboration with the American Liver Foundation.

Link to full program:
https://bit.ly/3OGHvOv

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Key Decisions in HIV Care: Considering Novel Therapies for HIV

support@deceraclinical.com (Christina Mussini MD, William R Short MD MPH AAHIVS) — Mon, 2 May 2022 22:20:00 +0000

In this episode from the series “Key Decisions in HIV Care,” Cristina Mussini, MD, and William R. Short, MD, MPH, AAHIVS, discuss novel therapies for HIV prevention and treatment, including:

Prevention
- Cabotegravir for pre-exposure prophylaxis (PrEP) with the latest results from the HPTN 083 and HPTN 084 studies
- Novel PrEP therapies in development, including islatravir and lenacapavir
Initial therapy
- Lenacapavir for initial therapy with results from the CALIBRATE study
Switch strategies
- Cabotegravir as a switch strategy with the latest results from the ATLAS-2M study, evaluating Q4W vs Q8W dosing, data on direct-to-inject without the oral lead-in, and data to date in pregnancy
Heavily treatment–experienced patients
- Currently available novel therapies for heavily treatment–experienced patients, including fostemsavir and ibalizumab
- Lenacapavir for heavily treatment–experienced patients with results from the CAPELLA study

Presenters:

Content based on an online CME program supported by educational grants from Gilead Sciences, Inc.; Janssen Therapeutics, Division of Janssen Products, LP; and ViiV Healthcare.

Follow along with the slides at:
https://bit.ly/3vWhjHj

Link to full program:
https://bit.ly/3fOl0XX

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A Model Intervention: Aiming for HCV Elimination in HIV-Positive MSM

support@deceraclinical.com (Dominique Laurent Braun MD) — Wed, 27 Apr 2022 20:30:00 +0000

In this podcast, Dr Dominique Laurent Braun discusses his micro-elimination program, the Swiss HCVree trial, designed to prevent hepatitis C virus (HCV) transmission among HIV-positive men who have sex with men. The study employed a test-and-treat approach to eliminate HCV infection in this key target population and could be a model for other countries to eliminate HCV infection in certain populations.

Presenter:

Dominique Laurent Braun, MD
Senior Staff Physician
Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich
University of Zurich
Zurich, Switzerland

Content based on an online CME program supported by independent educational grants from AbbVie and Gilead Sciences.

Link to full program:
https://bit.ly/3OGHvOv

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COVID-19: Which Drug, When, and Why? Antiviral Agents

support@deceraclinical.com (David A Wohl MD) — Mon, 25 Apr 2022 20:30:00 +0000

Antiviral agents continue to be effective against different strains of SARS-CoV-2 when used early in the disease course. In this episode, learn about the role of antiviral agents in hospitalized and high-risk nonhospitalized patients with COVID-19 and in different age groups. Listen as David A. Wohl, MD, discusses when and how to use IV and oral antiviral agents including:

Nirmatrelvir + ritonavir
Remdesivir
Molnupiravir

Presenter:
David A. Wohl, MD
Professor of Medicine
School of Medicine
Site Leader, Global Infectious Diseases
Clinical Trials Unit
University of North Carolina at Chapel Hill
Chapel Hill, North Carolina

Review the downloadable slidesets at:
https://bit.ly/3Ou4tbE

Link to full program:
https://bit.ly/3EBdf38

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COVID-19: Which Drug, When, and Why? Monoclonal Antibody Treatments

support@deceraclinical.com (Gregory Huhn MD MPHTM) — Thu, 21 Apr 2022 22:00:00 +0000

The place of monoclonal antibodies in COVID-19 is changing. In this episode, learn about their role in prophylaxis of patients who are at high risk of complications from acquiring COVID-19 or treatment of high-risk patients who have a mild to moderate COVID-19 infection. Listen as Gregory Huhn, MD, MPHTM, discusses when and how to use monoclonal antibodies including:

Bebtelovimab
Cilgavimab/tixagevimab
Sotrovimab

Presenter:

Gregory Huhn, MD, MPHTM
Associate Professor
Department of Infectious Diseases
Rush University Medical Center
Senior Director of HIV Services
Department of Infectious Diseases
Cook County Health
Chicago, Illinois

Review the downloadable slidesets at:
https://bit.ly/3xOfu1A

Link to full program:
https://bit.ly/3EBdf38

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How Stigma and Socioeconomic Barriers Impede HCV Care: Conversations Between Patient and Physician

support@deceraclinical.com (Oluwaseun Falade-Nwulia MBBS MPH) — Wed, 20 Apr 2022 20:30:00 +0000

In this episode, Oluwaseun Falade-Nwulia, MBBS, MPH, and a patient with previous injection drug use who has been cured of HCV infection discuss critical barriers that are preventing more people with current or previous injection drug use from receiving appropriate HCV care.

This insightful discussion underscores the negative effects of stigma toward people who inject drugs that exist in many clinical settings, the important role that socioeconomic factors such as transportation access and stable housing play in preventing access to HCV care, the effects of insufficient staffing at many addiction treatment centers, and the need for creative solutions to overcome these barriers.

Presenter:

Oluwaseun Falade-Nwulia, MBBS, MPH
Associate Professor
Division of Infectious Diseases
Johns Hopkins University School of Medicine
Attending
Division of Infectious Diseases
Johns Hopkins Hospital
Baltimore, Maryland

Content based on an online CME program supported by independent educational grants from AbbVie and Gilead Sciences, Inc. and developed in collaboration with the American Liver Foundation.

Link to full program:
https://bit.ly/3KmJvZt

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Long COVID

support@deceraclinical.com (Renslow Sherer MD) — Wed, 13 Apr 2022 22:35:00 +0000

In this episode, Renslow Sherer, MD, discusses what is known to date regarding long COVID, also known as postacute sequelae of COVID-19 infection, including:

Possible causes and risk factors
Signs and symptoms
Clinical management
Treatment options under consideration
Role of vaccination

Presenter:

Renslow Sherer, MD
Director, International HIV Training Center
Professor of Medicine
Section of Infectious Diseases and Global Health
Department of Medicine
University of Chicago
Chicago, Illinois

Review the downloadable slideset and the full program at:
https://bit.ly/3Ix8uZg

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Importance of Screening for HCC in HBV: Patient and Physician Sharing Session #7

support@deceraclinical.com (Ming-Lung Yu MD PhD) — Tue, 12 Apr 2022 20:00:00 +0000

In episode 7 of a series of sharing sessions between a physician and patient, Ming-Lung Yu, MD, PhD, and his patient, who is living with chronic hepatitis B, discuss:

Role of family history in risk of hepatocellular carcinoma (HCC)
Surveillance for HCC
Steps to take when diagnosed with HCC
How to live a healthy life after HCC diagnosis and treatment

Presenter:

Ming-Lung Yu, MD, PhD
Chair Professor
Hepatobiliary Division
Department of Internal Medicine and Hepatitis Center
Kaohsiung Medical University
Visiting Staff
Hepatobiliary Division
Department of Internal Medicine
Kaohsiung Medical University Hospital
Kaohsiung City, Taiwan

Content based on an online CME program supported by an independent educational grant from Gilead Sciences.

Link to full program:
https://bit.ly/37GY0cm

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COVID-19: Which Drug, When, and Why? Anti-inflammatory Agents and Immunomodulators

support@deceraclinical.com (Vikramjit Mukherjee MD) — Thu, 7 Apr 2022 21:00:00 +0000

Anti-inflammatory agents and immunomodulators are key components to treating patients who are severely or critically ill due to a COVID-19 infection.

In this episode, Vikramjit Mukherjee, MD, discusses the role and timing of these treatment options, including:

High-titer convalescent plasma
Corticosteroids
Interleukin-6 inhibitors (eg, tocilizumab)
Janus kinase inhibitors (eg, baricitinib)

Presenter:
Vikramjit Mukherjee, MD
Assistant Professor of Medicine
Division of Pulmonary, Critical Care, & Sleep Medicine
New York University School of Medicine
Director, Medical Intensive Care Unit
Bellevue Hospital
New York, New York

Review the downloadable slidesets at:
https://bit.ly/35NNb7Q

Link to full program:
https://bit.ly/35SrxQ0

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Key Decisions in HIV Care: Managing ART With Opportunistic Infections

support@deceraclinical.com (Cristina Mussini MD, William R. Short MD MPH AAHIVS) — Tue, 5 Apr 2022 20:00:00 +0000

In this episode from the series “Key Decisions in HIV Care,” Cristina Mussini, MD, and William R. Short, MD, MPH, AAHIVS, discuss important considerations for ART with opportunistic infections, including:

When to start ART with pneumocystis pneumonia including discussion of the ACTG 5164 study of immediate vs delayed ART with opportunistic infections
EACS, DHHS, and IAS-USA guideline recommendations for starting ART in the setting of most opportunistic infections
Considerations for the administration of ART to patients who are unable to swallow or critically ill and intubated
Treatment of Kaposi sarcoma and considerations for starting ART to avoid drug–drug interactions with Kaposi sarcoma treatment
Considerations for starting ART with cytomegalovirus and the risk for IRIS from cytomegalovirus
Discussion of treatment of cytomegalovirus and overlapping toxicities between its treatment and ART
When to start ART with cryptococcal meningitis and the data to support delayed treatment initiation with this particular opportunistic infection
EACS, DHHS, and IAS-USA guideline recommendations for starting ART in the setting of cryptococcal meningitis specifically
Treatment of cryptococcal meningitis and managing drug–drug interactions between ART and antifungal therapy

Presenters:
Cristina Mussini, MD
Head of Department of Infectious Diseases and Tropical Medicine
Full Professor of Infectious Diseases
Infectious Diseases Clinics
University Hospital
University of Modena and Reggio Emilia
Reggio Emilia, Italy

Content based on an online CME program supported by educational grants from Gilead Sciences, Inc.; Janssen Therapeutics, Division of Janssen Products, LP; and ViiV Healthcare.

Follow along with the slides at:
https://bit.ly/3uktrm1

Link to full program:
https://bit.ly/3q2DlGd

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Hepatitis Delta a Major Global Problem: Screening, Diagnosis, and Treatment in 2022 – Physician Discussion #1

support@deceraclinical.com (Heiner Wedemeyer MD) — Wed, 30 Mar 2022 19:30:00 +0000

In this episode, Heiner Wedemeyer, MD, discusses HDV epidemiology beyond the United States, the features of HDV/HBV pathology, insights into screening and diagnostic approaches, key aspects of disease staging, new treatment options, and important remaining clinical questions regarding optimal management of HDV.

Presenter:

Heiner Wedemeyer, MD
Professor and Chairman
Department of Gastroenterology, Hepatology and Endocrinology
Hannover Medical School
Hannover, Germany

Content based on an online CME program supported by independent educational grants from AbbVie and Gilead Sciences, Inc. and developed in collaboration with the American Liver Foundation.

Link to full program:
https://bit.ly/3KmJvZt

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The Ups and Downs of Living With HBV: Conversations Between Patient and Physician #4

support@deceraclinical.com (Paul Y. Kwo MD) — Fri, 25 Mar 2022 20:30:00 +0000

Episode 4 of this series features a conversation between a patient, Jason, and Paul Y. Kwo, MD, who discuss the particular challenges that can affect people with chronic hepatitis B seeking care in rural settings, including facing up to stigma, getting access to experienced medical practitioners, and searching for information and peer support.

Presenter:
Paul Y. Kwo, MD
Professor of Medicine
Director of Hepatology
Stanford University School of Medicine
Palo Alto, California

Content based on an online CME program supported by independent educational grants from AbbVie and Gilead Sciences.

Link to full program:
https://bit.ly/3KmJvZt

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Key Decisions in HIV Care: PrEP Considerations in Cisgender Men and Transgender Women

support@deceraclinical.com (Latesha Elopre MD, Karine Lacombe MD PhD) — Fri, 25 Mar 2022 18:00:00 +0000

In this episode from the series “Key Decisions in HIV Care,” Latesha Elopre, MD, MSPH, and Karine Lacombe, MD, PhD, discuss important considerations for PrEP in cisgender men and transgender women, including:

Discussion of the PrEP gap and racial and gender disparities in PrEP access
CDC, EACS, and WHO guidance on PrEP eligibility
PrEP regimens currently recommended for adults and adolescents including FTC/TDF daily, FTC/TAF daily, and long-acting cabotegravir
Data from clinical trials on the efficacy of FTC/TDF daily for men including Partners PrEP, TDF2, iPrEx, iPrEx OLE, and PROUD
Data from the ANRS IPERGAY study on the use of FTC/TDF on demand
Data from the DISCOVER trial on the use of FTC/TAF for PrEP
Data from the HPTN 083 study on the use of long-acting cabotegravir as PrEP for cisgender men
Clinical monitoring and considerations during PrEP use

Presenters:

Latesha Elopre, MD
Associate Professor
Division of Infectious Diseases
Assistant Dean of Diversity and Inclusion
General Medical Education
University of Alabama at Birmingham
Birmingham, Alabama

Karine Lacombe, MD, PhD
Professor
UMR-S1136
Sorbonne University
Head, Infectious Diseases Department
St Antoine Hospital, AP-HP
Paris, France

Content based on an online CME program supported by educational grants from Gilead Sciences, Inc.; Janssen Therapeutics, Division of Janssen Products, LP; and ViiV Healthcare.

Follow along with the slides at:
https://bit.ly/3uqPje3

Link to full program:
https://bit.ly/3q2DlGd

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Key Decisions in HIV Care: PrEP Considerations in Cisgender Women

support@deceraclinical.com (Latesha Elopre MD MSPH, Karine Lacombe MD PhD) — Thu, 24 Mar 2022 20:00:00 +0000

In this episode from the series “Key Decisions in HIV Care,” Latesha Elopre, MD, MSPH, and Karine Lacombe, MD, PhD, discuss important considerations for PrEP in cisgender women, including:

Discussion of the PrEP gap and racial and gender disparities in PrEP access
CDC, EACS, and WHO guidance on PrEP eligibility
PrEP regimens currently recommended for adults and adolescents including FTC/TDF daily, FTC/TAF daily, and long-acting cabotegravir
Data from phase III trials on the efficacy of FTC/TDF daily for women including Partners PrEP, TDF, VOICE, and FEM-PrEP
Pharmacokinetic data of FTC/TDF and FTC/TAF in the female genital tract and discussion of why on-demand dosing of FTC/TDF is not recommended in cisgender women
Data and recommendations for the use of the dapivirine ring from ASPIRE and The Ring Study and their open-label extensions, DREAM and HOPE
Data from the HPTN084 study on the use of long-acting cabotegravir as PrEP for cisgender women
Recommendations for the use of PrEP during pregnancy and breastfeeding
Clinical monitoring and considerations during PrEP use

Presenters:

Karine Lacombe, MD, PhD
Professor
UMR-S1136
Sorbonne University
Head, Infectious Diseases Department
St Antoine Hospital, AP-HP
Paris, France

Content based on an online CME program supported by educational grants from Gilead Sciences, Inc.; Janssen Therapeutics, Division of Janssen Products, LP; and ViiV Healthcare.

Follow along with the slides at:
https://bit.ly/36s2ovB

Link to full program:
https://bit.ly/3q2DlGd

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Lessons From Lockdown: HCC and Liver Transplant Care in the COVID-19 Era

support@deceraclinical.com (Graham R Foster FRCP PhD, Paul Y Kwo MD) — Wed, 23 Mar 2022 20:00:00 +0000

In this episode, Graham R. Foster, FRCP, PhD, and Paul Y. Kwo, MD, share lessons learned in the management of HCC and liver transplantation the COVID-19 era, including:

• Global impact of HCC and strategies for maintaining HCC care in the COVID-19 era
• Characteristics of liver transplant recipients in the COVID-19 era
• Impact of COVID-19 pandemic period on liver transplant outcomes
• Impact of liver transplant status on COVID-19 outcomes
• Strategies for providing streamlined care for patients with liver cancer or liver transplantation in the COVID-19 era

Presenters:

Graham R. Foster, FRCP, PhD
Professor of Hepatology
The Liver Unit
Consultant Hepatologist
Queen Mary University of London
London, United Kingdom

Paul Y. Kwo, MD
Professor of Medicine
Director of Hepatology
Stanford University School of Medicine
Palo Alto, California

Follow along with the slides at:
https://bit.ly/3HQ6dZ5

Link to full program:
https://bit.ly/3Bgyd5I

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Key Decisions in HIV Care: Considerations for Long-Acting Injectable PrEP

support@deceraclinical.com (Jason Schafer PharmD MPH) — Mon, 21 Mar 2022 20:00:00 +0000

In this episode, Jason Schafer, PharmD, MPH, explores key considerations for the use of long-acting injectable pre-exposure prophylaxis (PrEP).

- Listen as he gives his perspectives on:

- The FDA approval of long-acting cabotegravir for PrEP

- Healthcare professionals’ clinical concerns with long-acting injectable antiretroviral therapy

- Considerations for long-acting cabotegravir as PrEP

Dosing and administration
Managing missed doses
Discontinuation
Delays in HIV diagnoses found in the HPTN 083 study in men

- CDC recommendations for HIV screening while receiving PrEP

Presenter:

Jason Schafer, PharmD, MPH
Professor and Vice Chair
Jefferson College of Pharmacy
Thomas Jefferson University
Philadelphia, Pennsylvania

Follow along with the slides at:
https://bit.ly/3wugMOC

See the entire program at:
https://bit.ly/3q2DlGd

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Rational Use of New and Emerging Agents for Hepatitis Delta Virus

support@deceraclinical.com (Cihan Yurdaydin MD, Heiner Wedemeyer MD) — Wed, 16 Mar 2022 20:30:00 +0000

Hepatitis delta virus (HDV) is the most severe form of viral hepatitis and warrants new treatment options for better efficacy and tolerability. In part 2 of this 2-part podcast series, hear Heiner Wedemeyer, MD, and Cihan Yurdaydin, MD, discuss their thoughts on new and emerging treatment options for HDV and rational use of these new agents. Their discussion includes:

Assembly inhibitors (eg, lonafarnib)
Entry inhibitors (eg, bulevirtide)
Interferon lambda
Nucleic acid polymers
Small interfering RNA (siRNA) agents

Presenters:

Heiner Wedemeyer, MD
Professor and Chairman
Department of Gastroenterology, Hepatology, and Endocrinology
Hannover Medical School
Hannover, Germany

Cihan Yurdadin, MD
Professor and Chief
Department of Gastroenterology and Hepatology
Koç University Medical School
Istanbul, Turkey

Link to full program:
https://bit.ly/365VUlG

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Conference Conversations: HIV Advanced Practice Provider Perspectives from CROI 2022

Wed, 16 Mar 2022 19:15:00 +0000

In this episode, Jeffrey Kwong, DNP, MPH, FAANP, FAAN, and Susan LeLacheur, DrPH, PA-C, AAHIVS, share insights on new HIV data from CROI 2022, including:

Perinatal antiretroviral therapy exposure
Investigational formulation of long-acting contraception combined with pre-exposure prophylaxis
Monitoring with long-acting cabotegravir for pre-exposure prophylaxis
Myocardial infarction risk by HIV status

Presenters:

Jeffrey Kwong, DNP, MPH, FAANP, FAAN
Professor
Division of Advanced Nursing Practice
Rutgers School of Nursing
Newark, New Jersey
Nurse Practitioner
Gotham Medical Group
New York, New York

Susan LeLacheur, DrPH, PA-C, AAHIVS
Professor
PA Studies
The George Washington University School of Medicine and Health Sciences
Washington, DC

Link to full program:
https://bit.ly/3tdkXfJ

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HABP/VABP and Gram-Negative Resistance: Pathways to Early Effective Therapy

Tue, 15 Mar 2022 20:50:00 +0000

In this episode, Keith S. Kaye, MD, MPH; Lilian Abbo, MD, FIDSA; and Jason M. Pogue, PharmD, discuss HABP/VABP and gram-negative resistance including:

Epidemiology and burden of nosocomial bacterial pneumonia
Patient-specific risk factors for MDR pathogens
Improving outcomes with the use of antibiograms
Recommended empiric therapy for clinically suspected VABP
Antimicrobial resistance in HABP/VABP
Algorithms for gram-negative organism antibiotic-susceptibility testing
Using rapid diagnostic tests for HABP/VABP
New antimicrobial agents for MDR gram-negative infections with discussion of the 2021 IDSA guidance, and the following studies:
- ASPECT-NP: ceftolozane/tazobactam vs meropenem
- REPROVE: ceftazidime/avibactam vs meropenem
- RESTORE-IMI-1 imipenem/cilastatin/relebactam vs colistin + imipenem
- RESTORE-IMI-2: imipenem/cilastatin/relebactam vs piperacillin/tazobactam
- APEKS-NP: cefiderocol vs meropenem
- CREDIBLE-CR: cefiderocol vs best available therapy

Program Director:

Keith S. Kaye, MD, MPH
Chief
Division of Allergy, Immunology and Infectious Diseases
Professor of Medicine
Rutgers Robert Wood Johnson
Medical School
New Brunswick, New Jersey

Faculty:

Lilian Abbo, MD, FIDSA
Associate Chief Medical Officer in Infectious Diseases
Jackson Health System
Professor of Infectious Diseases
Department of Medicine & Miami Transplant Institute
University of Miami Miller School of Medicine
Miami, Florida

Jason M. Pogue, PharmD
Clinical Professor
Department of Clinical Pharmacy
University of Michigan College of Pharmacy
Infectious Diseases Clinical Pharmacist
Michigan Medicine
Ann Arbor, Michigan

Content based on a CME program supported by an educational grant from Merck Sharp & Dohme Corp.

Follow along with a downloadable slideset at:
https://bit.ly/3CEop6h

Link to full program
https://bit.ly/3i781lf

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Conference Conversations: HIV Pharmacist Perspectives from CROI 2022

support@deceraclinical.com (Fidelia Bernice PharmD, Jennifer Cocohoba PharmD) — Tue, 15 Mar 2022 20:50:00 +0000

In this episode, Fidelia Bernice, PharmD, and Jennifer Cocohoba, PharmD, share insights on new HIV data from CROI 2022, including:

Islatravir tissue and plasma distribution after monthly oral dosing
Pharmacokinetics, safety, and acceptability of a tenofovir vaginal ring
PrEP and Hormone Therapy in Transgender Individuals
Anticholinergic drug effects in older PWH
Adherence in PWH

Presenters:

Fidelia Bernice, PharmD
Clinical Pharmacy Specialist, Infectious Diseases
Department of Pharmacy
University of Maryland Medical Center
Baltimore, Maryland

Jennifer Cocohoba, PharmD
Professor
Department of Clinical Pharmacy
University of California, San Francisco
San Francisco, California

Link to full program:
https://bit.ly/3tdkXfJ

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Lessons From Lockdown: Viral Hepatitis Testing and Treatment in the COVID-19 Era—Audio Recap

support@deceraclinical.com (Jordan J. Feld MD MPH, Nancy Reau MD) — Mon, 14 Mar 2022 21:00:00 +0000

In this episode, Jordan J. Feld, MD, MPH, and Nancy Reau, MD, share lessons learned in the testing and treatment of viral hepatitis in the COVID-19 era, including:

Global impact of the COVID-19 pandemic on viral hepatitis testing and linkage to care
Impact of COVID-19 pandemic on testing and treatment in the United States and Canada
Innovative strategies to improve linkage to care of patients with viral hepatitis during the COVID-19 pandemic

Presenters:

Jordan J. Feld, MD, MPH
Professor of Medicine
University of Toronto
Hepatologist
Toronto Centre for Liver Disease
Sandra Rotman Centre for Global Health
Toronto, Canada

Follow along with the slides at:
https://bit.ly/3HQ6dZ5

Link to full program:
https://bit.ly/3Bgyd5I

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Key HIV Studies Influencing My Practice Following CROI 2022—Audio Recap

support@deceraclinical.com (Daniel R. Kuritzkes MD, David A. Wohl MD) — Mon, 14 Mar 2022 20:00:00 +0000

In this episode, Daniel R. Kuritzkes, MD, and David A. Wohl, MD, discuss new HIV data from CROI 2022, including:

Prevention strategies
LA therapies
Second-line therapies
The VISEND study comparing dolutegravir-based antiretroviral therapy (ART) vs protease inhibitor–based ART for second-line therapy
The NADIA study comparing dolutegravir with darunavir/ritonavir and tenofovir disoproxil fumarate with zidovudine for second-line therapy
Comorbidities and cure
ACTG A5324 (InMIND) study of ART intensification for cognitive impairment in people with HIV
IMPAACT P1107 case of patient with loss of HIV-1–specific antibody response and viral detection following CCR5∆32/∆32 cord/haploidentical transplant

Daniel R. Kuritzkes, MD
Chief, Division of Infectious Diseases
Brigham and Women’s Hospital
Harriet Ryan Albee Professor of Medicine
Harvard Medical School
Boston, Massachusetts

David A. Wohl, MD
Professor of Medicine
School of Medicine
Site Leader, Global Infectious Diseases Clinical Trials Unit
University of North Carolina at Chapel Hill

Content based on a CME program supported by educational grants from Gilead Sciences, Inc.; Janssen Therapeutics, Division of Janssen Products, LP; Merck Sharp & Dohme Corp; and ViiV Healthcare.

Follow along with an expanded slideset at:
https://bit.ly/3CItz0Z

Link to full program:
https://bit.ly/3tSpdAx

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Key Decisions in HIV Care: Data on Long-Acting Injectable PrEP

support@deceraclinical.com (Jason Schafer PharmD MPH) — Mon, 14 Mar 2022 20:00:00 +0000

In this episode, Jason Schafer, PharmD, MPH, explores the data for long-acting injectable pre-exposure prophylaxis (PrEP).

Listen as he gives his perspectives on the:

PrEP pipeline and the importance of having options for patients with differing preferences
FDA approval of long-acting cabotegravir for PrEP
HPTN 083 and 084 studies of long-acting cabotegravir for PrEP compared with oral emtricitabine/tenofovir disoproxil fumarate
Safety data on long-acting cabotegravir for PrEP
CDC recommendations on the management of injection-site reactions with cabotegravir for PrEP

Presenter:
Jason Schafer, PharmD, MPH
Professor and Vice Chair
Jefferson College of Pharmacy
Thomas Jefferson University
Philadelphia, Pennsylvania

Follow along with the slides at:
https://bit.ly/3tbvEPK

See the entire program at:
https://bit.ly/3q2DlGd

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Key Decisions in HIV Care: ART Considerations in the Inpatient Setting

support@deceraclinical.com (Jason Schafer PharmD MPH) — Mon, 14 Mar 2022 20:00:00 +0000

In this episode, Jason Schafer, PharmD, MPH, explores recommendations and data on managing antiretroviral therapy (ART) in the inpatient setting.

Listen as he gives his perspectives on:

Antiretroviral stewardship to prevent medication errors in the inpatient setting and at transitions of care
Renal and hepatic dosing considerations for ART
Drug–drug interaction considerations between ART and medications commonly encountered in the inpatient setting
Antiretroviral food effects
Administration of antiretrovirals in persons with swallowing difficulties

Presenter:
Jason Schafer, PharmD, MPH
Professor and Vice Chair
Jefferson College of Pharmacy
Thomas Jefferson University
Philadelphia, Pennsylvania

Follow along with the slides at:
https://bit.ly/36h5tOC

See the entire program at:
https://bit.ly/3q2DlGd

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Monitoring and Treating Patients Coinfected With HBV and HDV

support@deceraclinical.com (Heiner Wedemeyer MD, Cihan Yurdaydin MD) — Thu, 10 Mar 2022 21:30:00 +0000

Hepatitis delta virus (HDV) only exists in patients with hepatitis B virus (HBV) coinfection. In part 1 of this 2-part podcast series, hear Heiner Wedemeyer, MD, and Cihan Yurdaydin, MD, discuss their thoughts on serologic testing for both HDV and HBV and steps to take in monitoring, treating, and reassessing HBV in patients coinfected with HDV.

Presenters:

Heiner Wedemeyer, MD
Professor and Chairman
Department of Gastroenterology, Hepatology, and Endocrinology
Hannover Medical School
Hannover, Germany

Cihan Yurdaydin, MD
Professor and Chief, Department of Gastroenterology and Hepatology
Koç University Medical School
Istanbul, Turkey

Link to full program:
https://bit.ly/365VUlG

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Starting HBV Treatment in Pregnancy: Conversations Between Patient and Physician #3

support@deceraclinical.com (Anna Christina L. dela Cruz MD) — Mon, 7 Mar 2022 22:00:00 +0000

Episode 3 of this series features Anna Cristina L. dela Cruz, MD, in conversation with patient Melody Cheng about Melody’s decision to start hepatitis B virus (HBV) antiviral therapy during pregnancy. This podcast also discusses recommended approaches to preventing HBV transmission from mother to child, current recommendations on starting treatment for chronic HBV infection, and the issues around stopping treatment.

Presenter:
Anna Christina L. dela Cruz, MD
Associate Professor
Division of Digestive Diseases and Nutrition
Department of Internal Medicine
University of Kentucky
Lexington, Kentucky

Content based on an online CME program supported by independent educational grants from AbbVie and Gilead Sciences.

Link to full program:
https://bit.ly/3KmJvZt

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Hepatitis Delta Treatment: Where We Are and Where We Are Headed

support@deceraclinical.com (Stefan Zeuzem MD, Nancy Reau MD) — Thu, 3 Mar 2022 22:00:00 +0000

Treatment options for hepatitis delta virus (HDV) are lacking, but many exciting agents are under investigation. Hear Drs Nancy Reau and Stefan Zeuzem discuss their thoughts on up-and-coming agents for treating HDV, and explore what questions need answering to most effectively use currently available and emerging therapies, which include:

Bulevirtide
Interferon λ
Lonafarnib

Presenters:

Stefan Zeuzem, MD
Professor of Medicine
Chief, Department of Medicine I
JW Goethe University Hospital
Frankfurt, Germany

Link to full program:
https://bit.ly/3tlxa0H

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How Can We Destigmatize a Hepatitis B Diagnosis? Conversations Between Patient and Physician #2

support@deceraclinical.com (Robert G Gish MD) — Thu, 24 Feb 2022 21:20:00 +0000

In episode 2 of this series, tune in to a conversation between Robert G. Gish, MD, and patient advocate Jacki Chen, PhD, about the potential benefits of simplifying our approach to treating patients with chronic hepatitis B. The conversation focuses on the stigma many patients experience following diagnosis and how access to treatment may reduce this.

Presenter:

Robert G. Gish, MD
Professor of Medicine
Loma Linda University
Loma Linda, California
Adjunct Professor of Medicine
Nevada School of Medicine
Las Vega, Nevada
Clinical Professor
University of Nevada Reno School of Medicine
Clinical Professor
University of California Skaggs School of Pharmacy and Pharmaceutical Sciences
San Diego, California
Medical Director
Hepatitis B Foundation
Washington, DC

Content based on an online CME program supported by independent educational grants from AbbVie and Gilead Sciences.

Link to full program:
https://bit.ly/3lSkSui

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Lessons From Lockdown: Caring for Patients With Hepatitis B Virus Infection in the COVID-19 Era—Audio Recap

support@deceraclinical.com (Norah Terrault MD MPH, Grace LH Wong MD) — Thu, 24 Feb 2022 20:45:00 +0000

In this episode, Drs Norah Terrault, MD, MPH, and Grace LH Wong, MD, share lessons learned in the care of patients with hepatitis B virus (HBV) in the COVID-19 era, including:

HBV cascade of care before vs during the pandemic
Innovative strategies to improve HBV diagnosis and linkage to care
Lessons learned in telemedicine
Elimination through vaccination
Management of HBV and COVID-19 coinfection
Management of elevated liver enzymes in COVID-19

Presenters:

Norah Terrault, MD, MPH
Professor of Medicine
Chief of Gastrointestinal and Liver Diseases
University of Southern California
Los Angeles, California

Grace LH Wong, MD
Professor
Director, Medical Data Analytics Centre (MDAC)
Deputy Director, Center for Liver Health
Assistant Dean (Learning Experience), Faculty of Medicine
The Chinese University of Hong Kong
Honorary Consultant
Division of Gastroenterology and Hepatology
Department of Medicine and Therapeutics
Prince of Wales Hospital
Hong Kong

Follow along with the slides at:
https://bit.ly/3HQ6dZ5

Link to full program:
https://bit.ly/3Bgyd5I

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COVID-19: Omicron Transmissibility, Severity, and Vaccine Effectiveness

support@deceraclinical.com (Sharon R. Lewin AO FRACP PhD FAHMS) — Tue, 22 Feb 2022 14:00:00 +0000

In this episode, Sharon R. Lewin, AO, FRACP, PhD, FAHMS, discusses what is known about the SARS-CoV-2 omicron variant, including:

Transmissibility and infectiousness

Immune evasion

Disease severity

Risks of hospitalization and death

Vaccine effectiveness

2- vs 3-dose vaccine effectiveness
T-cell response

Presenter:

Sharon R. Lewin, AO, FRACP, PhD, FAHMS
Director, The Peter Doherty Institute for Infection and Immunity
Professor of Infectious Diseases
University of Melbourne
Consultant Infectious Diseases Physician
Alfred Hospital and Royal Melbourne Hospital
Melbourne, Australia

Review the downloadable slidesets at:
https://bit.ly/32tp2BT

https://bit.ly/3JKyNLW

Link to full program:
https://bit.ly/3Ix8uZg

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Importance of Treatment for HBV: Patient and Physician Sharing Session #6

support@deceraclinical.com (Tarik Asselah MD PhD) — Fri, 18 Feb 2022 23:00:00 +0000

In episode 6 of an ongoing series of sharing sessions between a physician and patient, Tarik Asselah, MD, PhD, and his patient, who is living with chronic hepatitis B (CHB), discuss:

Importance and goals of hepatitis B virus (HBV) treatment, with a call for broader access to treatment worldwide
Screening for HBV, especially given the frequency of asymptomatic disease
HBV vaccination as a preventive measure
Living a healthy life and maintaining hope while living with CHB

Presenter:

Tarik Asselah, MD, PhD
Professor of Medicine
Department of Hepatology
Hôpital Beaujon
Université de Paris
Clichy, France

Content based on an online CME program supported by an independent educational grant from Gilead Sciences.

Link to full program:
https://bit.ly/3565S64

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Key Decisions in HIV Care: Treating HIV/HCV Coinfection

support@deceraclinical.com (Mark S Sulkowski MD) — Wed, 16 Feb 2022 18:00:00 +0000

In this episode, Mark S. Sulkowski, MD, explores recommendations and data on treating HIV and hepatitis C virus (HCV) in patients who are coinfected.

Listen as he gives his perspectives on:

Prioritization of both HIV and HCV treatment
Efficacy of HCV direct-acting antivirals in people with HIV
American Association for the Study of Liver Diseases/Infectious Diseases Society of America recommendations for first-line HCV treatment in HIV/HCV coinfection
International guidance on first-line antiretroviral therapy
HIV/HCV drug–drug interactions
The Swiss HCVree Trial of HCV treatment as prevention in men who have sex with men with HIV
Dependence of HCV elimination on the HIV care continuum for people who are HIV/HCV coinfected

Presenter:

Mark S. Sulkowski, MD
Professor of Medicine
Medical Director, Viral Hepatitis Center
Chief, Infectious Disease
Johns Hopkins Bayview Medical Center
Johns Hopkins University School of Medicine
Baltimore, Maryland

Follow along with the slides at:
https://bit.ly/3oUi29g

Link to full program:
https://bit.ly/3fOl0XX

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My Management Strategies for NASH in Patients With HIV

support@deceraclinical.com (Mark S. Sulkowski MD) — Tue, 15 Feb 2022 21:30:00 +0000

In this episode, Mark S. Sulkowski, MD, discusses his recommended approach for managing nonalcoholic steatohepatitis in patients with HIV, including recognizing nonalcoholic steatohepatitis, recommending lifestyle interventions, and considering pharmacologic approaches.

Presenter:

Mark S. Sulkowski, MD
Professor of Medicine
Medical Director, Viral Hepatitis Center
Chief, Infectious Disease
Johns Hopkins Bayview Medical Center
Johns Hopkins University School of Medicine
Baltimore, Maryland

Content based on an online CME program supported by an educational grant from Theratechnologies Inc.

Link to full program:
https://bit.ly/3Gk7juJ

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Lessons From Lockdown: Hepatitis Delta Elimination Strategies in the COVID-19 Era

Fri, 11 Feb 2022 21:30:00 +0000

In this episode, Robert G. Gish, MD, and Pietro Lampertico, MD, PhD, share lessons learned in the care of patients coinfected with hepatitis B virus and hepatitis delta virus (HDV), including:

Burden of HDV infection
Chronic HDV infection and comorbidities
Impact of COVID-19 on care of patients with chronic hepatitis B
Screening for HDV and which assays to use
Screening for viral hepatitis at a COVID-19 vaccination site

Presenters:

Robert G. Gish, MD, FAASLD, AGAF, FAST
Professor of Medicine
Loma Linda University
Loma Linda, California
Clinical Professor
University of Nevada Reno School of Medicine
Reno, Nevada
University of California Skaggs School of Pharmacy and Pharmaceutical Sciences
San Diego, California
Medical Director
Hepatitis B Foundation
Washington, DC

Pietro Lampertico, MD, PhD
Professor of Gastroenterology
Director, Division of Gastroenterology and Hepatology
IRCCS Ca Granda Policlinico Hospital
University of Milan
Milan, Italy

Follow along with the slides at:
https://bit.ly/3HQ6dZ5

Link to full program:
https://bit.ly/3Bgyd5I

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Key Decisions in HIV Care: Renal and Hepatic Considerations in Older PWH

Thu, 10 Feb 2022 21:30:00 +0000

In this episode from the series “Key Decisions in HIV Care,” Jonathan Appelbaum, MD, FACP, AAHIVS, and Jens D. Lundgren, MD, DMSc, discuss important considerations for antiretroviral therapy (ART) use in older patients with renal and hepatic impairment.

European AIDS Clinical Society guideline screening recommendations for kidney disease in people with HIV
Antiretroviral dose adjustment recommendations based on estimated glomerular filtration rate
Data on the use of full-dose lamivudine with renal impairment
Data on the use of 2-drug nucleos(t)ide reverse-transcriptase inhibitor–sparing ART regimens, including GEMINI-1 and -2, TANGO, and SALSA for dolutegravir/lamivudine; SWORD-1 and -2 for dolutegravir/lamivudine; and ATLAS and FLAIR for long-acting cabotegravir plus rilpivirine
US Department of Health and Human Services recommendations on the use of ART agents with hepatic impairment
Recommendations from the American Gastroenterological Association on screening and diagnosis of nonalcoholic fatty liver disease (NAFLD)
Prevalence of NAFLD, nonalcoholic steatohepatitis, and liver fibrosis in people with HIV
Overlapping risk factors between HIV and NAFLD

Presenters:

Jonathan Appelbaum, MD, FACP, AAHIVS
Laurie L. Dozier Jr, MD, Education Director
Professor of Internal Medicine
Chair, Department of Clinical Sciences
Florida State University College of Medicine
Tallahassee, Florida

Content based on an online CME program supported by educational grants from Gilead Sciences, Inc.; Janssen Therapeutics, Division of Janssen Products, LP; and ViiV Healthcare.

Follow along with the slides at:
https://bit.ly/3gAsu19

Link to full program:
https://bit.ly/3fOl0XX

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Don’t Forget About the Liver! NASH in Patients with HIV: Answering the Questions Forum

support@deceraclinical.com (Jürgen K. Rockstroh MD, Giada Sebastiani MD) — Wed, 9 Feb 2022 22:00:00 +0000

In this episode, Jürgen K. Rockstroh, MD, and Giada Sebastiani, MD, discuss key strategies to appropriately screen for, identify, and manage nonalcoholic steatohepatitis in persons with HIV. They also answer pressing questions from healthcare professionals.

Presenters:

Jürgen K. Rockstroh, MD
Professor of Medicine
University Hospital Bonn
Department of Medicine I
Bonn, Germany

Giada Sebastiani, MD
Associate Professor of Medicine
McGill University Health Centre
Division of Gastroenterology and Hepatology and Division of Infectious Diseases
Clinician Scientist
Research Institute of McGill University Health Centre
Montreal, Quebec, Canada

Content based on an online CME program supported by an educational grant from Theratechnologies Inc.

Link to full program:
https://bit.ly/363orZ9

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NASH in PWH: Key Strategies for Screening and Identification

support@deceraclinical.com (Jürgen K. Rockstroh MD) — Thu, 3 Feb 2022 21:30:00 +0000

In this episode, Jürgen K. Rockstroh, MD, discusses his recommended approach for diagnosing nonalcoholic steatohepatitis in patients with HIV, the value of noninvasive diagnostic tests such as serum biomarkers and elastography, and how timely nonalcoholic fatty liver disease assessment and metabolic risk factor determination can result in early interventions.

Presenter:
Jürgen K. Rockstroh, MD
Professor of Medicine
University Hospital Bonn
Department of Medicine I
Bonn, Germany

Content based on an online CME program supported by an educational grant from Theratechnologies Inc.

Link to full program:
https://bit.ly/3Gk7juJ

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Key Decisions in HIV Care: Considering the Use of Proviral DNA Genotyping to Inform ART Choice

support@deceraclinical.com (John D Baxter MD) — Tue, 1 Feb 2022 16:30:00 +0000

In this episode, John D. Baxter, MD, explores recommendations and data on the use of proviral DNA genotyping to inform antiretroviral therapy (ART) choice for patients who are treatment experienced.

Listen as he gives his perspectives on:

US Department of Health and Human Services guideline recommendations on the use of proviral DNA genotyping
US Department of Health and Human Services guideline recommendations and supporting data on switching ART with viral suppression and underlying drug resistance
Study 380-4030 on outcomes with bictegravir- and dolutegravir-based ART in patients with preexisting nucleos(t)ide reverse-transcriptase inhibitor resistance
The BRAAVE 2020 study on switching to bictegravir/emtricitabine/tenofovir alafenamide in Black persons with HIV, some of whom had baseline ART resistance
Between-class ART switches with underlying resistance
Susceptibility of tenofovir disoproxil fumarate and abacavir with thymidine analogue mutations

Presenter:

John D. Baxter, MD
Professor of Medicine
Division of Infectious Diseases
Department of Pathology
Cooper Medical School of Rowan University
Head, Division of Infectious Diseases
Cooper University Health Care
Camden, New Jersey

Follow along with the slides at:
https://bit.ly/3HmkSLc

See the entire program at:
https://bit.ly/3fOl0XX

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Tackling Racial Inequities in HIV Care Globally

Wed, 26 Jan 2022 20:25:00 +0000

In this episode, Rageshri Dhairyawan, MBBS, BSc, FRCP, DipGUM, DFSRH, DipHIV, and Solange L. Baptiste, ScM, discuss the burden of HIV among BIPOC and migrant communities and key strategies to reduce racial disparities in HIV care globally:

Disproportionate impact of HIV among BIPOC communities and migrant populations globally
Barriers to HIV testing, prevention, and treatment services among BIPOC communities and migrant populations
Strategies to overcome health system–based and provider-based barriers to engagement with HIV care

Rageshri Dhairyawan, MBBS, BSc, FRCP, DipGUM, DFSRH, DipHIV
Honorary Senior Lecturer in HIV Medicine
Blizard Institute, Faculty of Medicine and Dentistry
Queen Mary University of London
Consultant Physician in HIV Medicine
Department of Infection and Immunity
Barts Health NHS Trust
London, United Kingdom

Solange L. Baptiste, ScM
Executive Director
International Treatment Preparedness Coalition
Bryanston, South Africa

Content based on a CME program supported by educational grants from AbbVie; Gilead Sciences, Inc.; and Janssen Therapeutics, Division of Janssen Products, LP

To follow along, download the slides at:
https://bit.ly/3ngDrsv

Link to full program:
https://bit.ly/3gh6WXj

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Key Decisions in HIV Care: Choosing Initial ART in PWH With Transmitted Drug Resistance

support@deceraclinical.com (John D. Baxter MD) — Tue, 25 Jan 2022 22:40:00 +0000

In this episode, John D. Baxter, MD, explores recommendations and data on choosing antiretroviral therapy with transmitted drug resistance.

Listen as he gives his perspectives on:

Initial response to antiretroviral therapy during primary HIV infection with baseline resistance
Data from the START study on treatment-naive patients with transmitted drug resistance by region and drug class
Recommendations from the US Department of Health and Human Services and International AIDS Society–USA guidelines on baseline genotype testing for integrase strand transfer inhibitor resistance
Considerations for the use of second-generation integrase strand transfer inhibitors and darunavir with transmitted drug resistance
Cases of transmitted multidrug-resistant HIV in patients receiving pre-exposure prophylaxis

Presenter:
John D. Baxter, MD
Professor of Medicine
Division of Infectious Diseases
Department of Pathology
Cooper Medical School of Rowan University
Head, Division of Infectious Diseases
Cooper University Health Care
Camden, New Jersey

Follow along with the slides at:
https://bit.ly/3u7pjWq

See the entire program at:
https://bit.ly/3fOl0XX

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Omicron Variant: Effects on Treatments for COVID-19

support@deceraclinical.com (Arthur Kim MD) — Tue, 25 Jan 2022 21:30:00 +0000

The SARS-CoV-2 omicron variant has affected which of our COVID-19 treatment strategies are currently effective, with some expected to maintain their efficacy and some expected to lose their efficacy. In this episode, Arthur Kim, MD, discusses the effects of the SARS-CoV-2 omicron variant on many of the COVID-19 approved, authorized, and investigational treatment options, including:

Direct-acting, small-molecule antiviral agents such as molnupiravir, nirmatrelvir + ritonavir, and remdesivir
Monoclonal antibody treatments such as bamlanivimab + etesevimab, casirivimab + imdevimab, cilgavimab + tixagevimab, regdanvimab, and sotrovimab

Presenter:

Arthur Kim, MD
Associate Professor
Department of Medicine
Harvard Medical School
Director, Viral Hepatitis Clinic
Division of Infectious Diseases
Massachusetts General Hospital
Boston, Massachusetts

Review the downloadable slidesets at:
https://bit.ly/3FXc90w
https://bit.ly/32tp2BT

Link to full program:
https://bit.ly/3Ix8uZg

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Tackling Racial Inequities in HIV Care in the United States

support@deceraclinical.com (Samantha V. Hill MD MPH, David Malebranche MD MPH) — Wed, 12 Jan 2022 21:00:00 +0000

In this episode, Samantha V. Hill, MD, MPH, and David Malebranche, MD, MPH, examine key facilitators to tackling racial inequities in HIV care, including:

Barriers to HIV testing, prevention, and treatment services in BIPOC communities and migrant populations
Facilitators to HIV testing, prevention, and treatment services in BIPOC communities and migrant populations
Strategies to overcome health system–based and healthcare professional–based barriers to engagement with HIV care

Samantha V. Hill, MD, MPH
Assistant Professor
Division of Adolescent Medicine
Department of Pediatrics
The University of Alabama at Birmingham
Birmingham, Alabama

David Malebranche, MD, MPH
Internal Medicine Physician
HIV/Sexual Health Specialist
AIDS Healthcare Foundation (AHF) Medical Clinic
Atlanta, Georgia

Content based on a CME program supported by educational grants provided by AbbVie; Gilead Sciences, Inc.; and Janssen Therapeutics, Division of Janssen Products, LP

To follow along, download the slides at:
https://bit.ly/3ngDrsv

Link to full program:
https://bit.ly/3gh6WXj

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Key Decisions in HIV Care: ART Considerations With Coinfections

support@deceraclinical.com (Daria Podlekareva MD PhD, Mark S Sulkowski MD) — Mon, 10 Jan 2022 21:45:00 +0000

In this episode from the series “Key Decisions in HIV Care,” Daria Podlekareva, MD, PhD, and Mark S. Sulkowski, MD, discuss important considerations for ART use in patients with coinfections, including:

DHHS testing and treatment recommendations for HBV in patients with HIV
Data suggesting that tenofovir alone may not suppress HBV in all PWH
Data from NA-ACCORD showing that incomplete HBV DNA suppression is associated with HCC in patients with HIV/HBV
Data for the use of entecavir as an add-on therapy if an HIV ART regimen is not HBV active
Data showing that lamivudine alone is associated with resistance in patients with HIV/HBV
Discussion of HBV management in the setting of 2-drug regimens for HIV if the patient is coinfected
Recommendations from the DHHS, EACS, and WHO to start ART as soon as possible in patients with TB/HIV coinfection
Data from the SAPiT, ACTG A5221 STRIDE, and CAMELIA studies to show the benefits of early ART in patients with TB/HIV
Recommendations from the EACS guidelines on what ART regimens are recommended with TB/HIV
Drug-drug interaction considerations between ART and TB treatment
Discussion of the prevention and management of TB-associated IRIS

Presenters:

Daria Podlekareva, MD, PhD
Centre of Excellence for Health, Immunity and Infection (CHIP)
Rigshospital, University of Copenhagen
Copenhagen, Denmark

Mark S. Sulkowski, MD
Professor of Medicine
Medical Director, Viral Hepatitis Center
Chief, Infectious Disease
Johns Hopkins Bayview Medical Center
Johns Hopkins University School of Medicine
Baltimore, Maryland

Content based on an online CME program supported by educational grants from Gilead Sciences, Inc.; Janssen Therapeutics, Division of Janssen Products, LP; and ViiV Healthcare.

Follow along with slides:
https://bit.ly/3zHySMO

See the entire program at:
https://bit.ly/2TXTYWx

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Key Decisions in HIV Care: Is There a Role for PIs in Current Practice?

support@deceraclinical.com (Karen Ha MD) — Thu, 6 Jan 2022 21:40:00 +0000

In this episode, Karen Ha, MD, explores recommendations and data on the role of PIs in current practice.

Listen as she gives her perspectives on:

DHHS guideline recommendations on the use of PI-based ART
Data from the DIAMOND study on the use of boosted DRV for rapid initiation
Data from the EARNEST and NADIA studies on the use of PI-based ART with NRTI resistance
Considerations for the use of PIs in patients with cardiovascular risk, including data from the D:A:D study
Key drug–drug interaction considerations with the use of PIs

Presenter:

Karen Ha, MD
Assistant Professor of Medicine
Division of Infectious Diseases
Department of Medicine
Cooper University Hospital
Cooper Medical School of Rowan University
Camden, New Jersey

Follow along with the slides at:
https://bit.ly/3zvO6EB

See the entire program at:
https://bit.ly/2TXTYWx

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COVID-19 Oral Antiviral Agents

support@deceraclinical.com (Renslow Sherer MD) — Thu, 6 Jan 2022 21:30:00 +0000

In this episode, Renslow Sherer, MD, discusses key data on COVID-19 oral antiviral agents—molnupiravir and nirmatrelvir (PF-07321332) plus ritonavir—for nonhospitalized adults with mild to moderate COVID-19, including:

EPIC-HR study of nirmatrelvir (PF-07321332) plus ritonavir
- Safety data
- Efficacy data
MOVe-OUT study of molnupiravir
- Safety data
- Efficacy data
Roles in treatment of COVID-19
- Timing of treatment

Presenter:

Review the downloadable slideset at:
https://bit.ly/31wi1Qi

Link to full program:
https://bit.ly/3EH2485

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Key Decisions in HIV Care: Is There a Role for NNRTIs in Current Practice?

support@deceraclinical.com (Karen Ha MD) — Thu, 6 Jan 2022 21:30:00 +0000

In this episode, Karen Ha, MD, explores recommendations and data on the role of NNRTIs in current practice.

Listen as she gives her perspectives on:

DHHS guideline recommendations on the use of NNRTI-based ART
Weight gain data from the ADVANCE study, DRIVE-AHEAD, DRIVE-FORWARD, DRIVE-SHIFT, and a multivariate analysis of weight gain on ART
Key food effects and drug–drug interaction considerations with the use of NNRTIs

Presenter:

Karen Ha, MD
Assistant Professor of Medicine
Division of Infectious Diseases
Department of Medicine
Cooper University Hospital
Cooper Medical School of Rowan University
Camden, New Jersey

Follow along with the slides at:
https://bit.ly/3G2PS2p

See the entire program at:
https://bit.ly/2TXTYWx

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Personal Perspectives on HIV PrEP Use: My Decision, My Experience

support@deceraclinical.com (Christian R Pollard) — Mon, 3 Jan 2022 21:25:00 +0000

In this episode, Christian R. Pollard provides his perspectives as an individual taking daily oral HIV PrEP, including factors he considered in the decision to use PrEP, his experience with taking PrEP (daily pills and periodic laboratory testing), and his thoughts on what opportunities future PrEP options may offer.

Presenter:

Christian R. Pollard

Content based on an online CME program supported by an independent educational grant from Gilead Sciences, Inc.

Link to full program:
https://bit.ly/3AFvsZY

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Key Decisions in HIV Care: Choosing ART in the Context of Virologic Failure and Resistance

support@deceraclinical.com (Josep M. Llibre MD PhD, W. David Hardy MD) — Wed, 29 Dec 2021 22:15:00 +0000

In this episode from the series “Key Decisions in HIV Care,” W. David Hardy, MD, and Josep M. Llibre, MD, PhD, discuss important considerations for ART use in the context of virologic failure and resistance, including:

A discussion of the definitions of the following: highly treatment experienced, complex ART, multidrug-resistant HIV, and limited treatment options
The scope of the problem, including data from the CNICS cohort
DHHS and EACS guideline recommendations on the management of virologic failure and drug resistance, including recommendations for the use of genotypic and phenotypic genotyping and proviral DNA sequencing
Construction of an optimized background regimen with discussion of the OPTIONS, DAWNING, NADIA, and VIKING-3 trials
Novel treatment options, including ibalizumab and data from TMB-301/-311, fostemsavir and data from BRIGHTE, and lenacapavir and data from CAPELLA

Presenters:

W. David Hardy, MD
Scientific and Medical Consultant
Adjunct Clinical Professor of Medicine
Division of Infectious Diseases
Keck School of Medicine of USC
Los Angeles, California

Josep M. Llibre, MD, PhD
Senior Consultant Physician and Clinical Researcher
Infectious Disease and “Fight against AIDS and Infectious Diseases Foundation”
Hospital Universitari Germans Trias i Pujol
Badalona
Barcelona, Spain

Content based on an online CME program supported by educational grants from Gilead Sciences, Inc.; Janssen Therapeutics, Division of Janssen Products, LP; and ViiV Healthcare.

Follow along with the slides at:
https://bit.ly/3z9AtL0

Link to full program:
https://bit.ly/2TXTYWx

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Individualized Choices in Antiretroviral Therapy: Present and Future

Tue, 21 Dec 2021 21:00:00 +0000

Hear insights from 3 faculty experts as they present emerging data and guidelines and engage in discussion on patient-centered ART selection for people with HIV.

Topics include assessing treatment options; individualizing ART for women of childbearing potential and during pregnancy, patients with OIs, and during the COVID-19 pandemic; and new data on investigational ART strategies.

Learn how to:

Apply the results of recent clinical studies and evolving treatment guidelines on the timing and choice of first-line ART and switch strategies and managing treatment-experienced patients with HIV
Integrate individual patient factors such as drug–drug interactions, comorbidities, pregnancy status, adherence, and dosing preferences when selecting optimal ART
Appropriately counsel patients regarding the anticipated clinical role of new and investigational ART regimens in individualized care

Presenters:
Chloe Orkin, MBChB, FRCP, MD
Professor of HIV
Queen Mary, University of London
Consultant Physician
Lead for HIV Research
Barts Health NHS Trust
The Royal London Hospital
London, United Kingdom

Jean-Michel Molina, MD, PhD
Head of the Department of
Infectious Diseases
Saint-Louis Hospital, Assistance-Publique Hôpitaux de Paris
Professor of Infectious Diseases
University of Paris
Paris, France

Cristina Mussini, MD
Head of Department of Infectious Diseases and Tropical Medicine
Full Professor of Infectious Diseases
Infectious Diseases Clinics
University Hospital
University of Modena and Reggio Emilia
Reggio Emilia, Italy

Follow along with the slides at:
https://bit.ly/329c8ZP

See the entire program at:
https://bit.ly/3FkRofM

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Key Decisions in HIV Care: Polypharmacy and Cardiovascular Risk Considerations in Older PWH

Tue, 21 Dec 2021 17:00:00 +0000

In this episode from the series “Key Decisions in HIV Care,” Jonathan Appelbaum, MD, FACP, AAHIVS, and Jens D. Lundgren, MD, DMSc, discuss important considerations for ART use in older PWH, including:

DHHS, EACS, IAS, and WHO recommendations for first-line ART
Virologic outcomes for older PWH in clinical trials and results from the HealthHIV Second Annual National Survey
Polypharmacy and its potential consequences, including common non-ARV medications prescribed in the VACS cohort, drug–drug interactions with common concomitant medications, common comorbidities in older PWH, and drug–disease state interactions including renal and hepatic impairment
Cardiovascular risk considerations including data from the D:A:D study and RESPOND cohort and lipid changes in the TANGO study of switching to DTG/3TC from TAF-based ART

Presenters:

Jonathan Appelbaum, MD, FACP, AAHIVS
Laurie L. Dozier Jr, MD, Education Director
Professor of Internal Medicine
Chair, Department of Clinical Sciences
Florida State University College of Medicine
Tallahassee, Florida

Jens D. Lundgren, MD, DMSc
Professor
Rigshospital, University of Copenhagen
Copenhagen, Denmark
Director
Centre of Excellence for Health, Immunity and Infection (CHIP)
Rigshospital, University of Copenhagen
Copenhagen, Denmark

Content based on an online CME program supported by educational grants from Gilead Sciences, Inc.; Janssen Therapeutics, Division of Janssen Products, LP; and ViiV Healthcare.

Follow along with the slides at:
https://bit.ly/3miT6qH

See the entire program at:
https://bit.ly/2TXTYWx

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Universal Screening for Hepatitis Delta

support@deceraclinical.com (Maria Buti MD, Robert G. Gish MD) — Mon, 20 Dec 2021 20:00:00 +0000

Hepatitis delta is the most severe form of viral hepatitis, and many patients remain undiagnosed. In this episode, Maria Buti, MD, and Robert G. Gish, MD, discuss the prevalence and severity of hepatitis delta. Hear their personal experiences from the clinic and their call to action for universal screening of patients with hepatitis B for coinfection with hepatitis delta.

Presenters:
Maria Buti, MD
Professor of Medicine
Hospital Universitario Vall d'Hebron
Barcelona, Spain

Robert G. Gish, MD
Professor of Medicine
Loma Linda University
Loma Linda, California
Medical Director
Hepatitis B Foundation
Washington, DC

Link to full program:
https://bit.ly/3E9xKSx

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Key Decisions in HIV Care: Assessing Candidacy for Long-Acting ART

support@deceraclinical.com (Milena Murray PharmD MSc BCIDP AAHIVP) — Thu, 16 Dec 2021 21:30:00 +0000

In this episode, Milena Murray, PharmD, MSc, BCIDP, AAHIVP, explores recommendations and data on patient specific factors associated with LA CAB plus RPV failure.

Listen as she gives her perspectives on:

LA CAB plus RPV pharmacokinetic data
DHHS guideline recommendations on which patients can be considered for LA CAB plus RPV
Data from the ATLAS, FLAIR, and ATLAS-2M studies on patients with virologic failure and the factors that may have contributed

Presenter:

Milena Murray, PharmD, MSc, BCIDP, AAHIVP
Associate Professor
Pharmacy Practice
Midwestern University College of Pharmacy
Downers Grove Campus
Downers Grove, Illinois
HIV/ID Clinical Pharmacist
Northwestern Memorial Hospital
Chicago, Illinois

Follow along with the slides at:
https://bit.ly/3EfaSRX

See the entire program at:
https://bit.ly/2TXTYWx

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Tackling Racial Inequalities in HBV Care Globally

Wed, 15 Dec 2021 21:30:00 +0000

In this episode, Geoffrey Dusheiko, FRCP, FRCP (Edin), FCP (SA), and Ming-Lung Yu, MD, PhD, discuss key racial inequities of care that lead to undertreatment for migrant populations and other racial minorities globally with or at risk for hepatitis B. In addition, they discuss plans to improve engagement across the care continuum and strategies to combat implicit racial biases that affect optimal HBV care.

Topics include:

Differences in the burden of HBV globally
Suboptimal engagement of HBV care
Stigma associated with HBV care
Key strategies for overcoming racial barriers
First-hand patient stories

Geoffrey Dusheiko, FRCP, FRCP (Edin), FCP (SA)
Emeritus Professor of Medicine
Consultant Hepatologist
University College London Medical School
Professor
Liver Unit
Kings College Hospital
London, United Kingdom

Content based on a CME program supported by educational grants provided by AbbVie; Gilead Sciences, Inc.; and Janssen Therapeutics, Division of Janssen Products, LP

To follow along, download the slides at:
https://bit.ly/3gWStjZ

Link to full program:
https://bit.ly/3kKIb9a

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Shingles in the COVID-19 Era: Increasing Shingles Vaccine Uptake—Audio Recap

support@deceraclinical.com (Dalilah Restrepo MD) — Tue, 14 Dec 2021 17:50:00 +0000

In this episode, Dalilah Restrepo, MD, discusses barriers to shingles vaccination and strategies to increase routine vaccine uptake in the COVID-19 era.

Using the latest data and expert guidance, this podcast covers topics such as:

Shingles disease burden and increasing incidence over time
Decline in shingles vaccination rates in the COVID-19 era
National Vaccine Advisory Committee standards of care
CDC guidance catching up after RZV dosing delays
Strategies to increase shingles vaccine uptake

Presenter:

Dalilah Restrepo, MD
Infectious Diseases Specialist
Fountain Valley Hospital
Fountain Valley, California

Content based on a CME program supported by an educational grant from GlaxoSmithKline

Follow along with the downloadable slides at:
https://bit.ly/3pW7Bl8

Link to full program:
https://bit.ly/3o4PB8N

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COVID-19 Vaccination: Third Doses and Boosters

support@deceraclinical.com (Renslow Sherer MD) — Fri, 10 Dec 2021 21:30:00 +0000

In this episode, Renslow Sherer, MD, discusses key data on COVID-19 vaccine efficacy, including:

Third doses
Booster doses
Mixing and matching booster doses

Presenter:

Review the downloadable slideset at:
https://bit.ly/3Fl0yZV

Link to full program:
https://bit.ly/3EH2485

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Key Studies on Vaccine-Preventable Diseases Influencing My Practice Following IDWeek 2021

support@deceraclinical.com (Martin C Mahoney MD PhD) — Mon, 6 Dec 2021 22:15:00 +0000

In this episode, Martin C. Mahoney, MD, PhD, discusses new data on vaccine-preventable diseases from IDWeek 2021, including:

Pneumococcal disease
Respiratory syncytial virus (RSV)
Herpes zoster
Influenza

Presenter:

Martin C. Mahoney, MD, PhD
Professor of Oncology
Department of Internal Medicine
Roswell Park Comprehensive
Cancer Institute
Buffalo, New York

Follow along with an expanded slideset at:
https://bit.ly/3Ev8ozr

Link to full program:
https://bit.ly/3BCHF2E

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Key Viral Hepatitis Studies Influencing My Practice Following AASLD 2021

support@deceraclinical.com (Nancy Reau MD) — Wed, 1 Dec 2021 17:50:00 +0000

In this episode, Nancy Reau, MD, discusses new viral hepatitis data from AASLD 2021, including:

HBV treatment in pregnancy
Outcomes following HBV treatment withdrawal
Progress toward an HBV cure
HCV implementation science and current status of the cascade of care
Hepatitis delta virus: understanding the clinical impact
Phase III clinical trial updates for hepatitis delta virus, including data on bulevirtide

Presenter:

Nancy Reau, MD
Professor of Medicine
Chief, Section of Hepatology
Associate Director, Solid Organ Transplantation
Richard B. Capps Chair of Hepatology
Rush University Medical Center
Chicago, Illinois

Follow along with the downloadable slideset at:
https://bit.ly/3d6NQRV

Link to full program:
https://bit.ly/3lputrT

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Key Studies Influencing My Practice Following EACS 2021—Audio Recap

support@deceraclinical.com (Tristan J. Barber MA MD FRCP) — Tue, 30 Nov 2021 21:30:00 +0000

In this episode, Tristan J. Barber, MA, MD, FRCP, discusses new HIV data from EACS 2021, including:

First-line therapies
- BIC/FTC/TAF in a test-and-treat model in IMEA 055 FAST
- Week 144 data of ISL + DOR in treatment-naive patients from P011
Switch Strategies
- Data on the use of DTG/3TC in patients with an M184V mutation from SOLAR 3D and the French Dat’AIDS Cohort
Long-Acting Therapies
- Efficacy and safety of LA CAB + RPV by BMI
- Long-term follow-up of participants who discontinued LA CAB + RPV in the ATLAS, ATLAS-2M, and FLAIR trials
- Patient satisfaction with LA CAB + RPV from the CARISEL study
- Resistance and subgroup data from the CAPELLA study of lenacapavir in heavily treatment–experienced patients
COVID-19 vaccination efficacy and the impact of the pandemic on viral suppression in PWH

Presenter:

Tristan J. Barber, MA, MD, FRCP
Consultant in HIV Medicine
Ian Charleson Day Centre
Royal Free Hospital
Honorary Associate Professor
Institute for Global Health
University College London
London, United Kingdom

Content based on a CME program supported by educational grants from Gilead Sciences, Inc.; Merck Sharp & Dohme Corp; and ViiV Healthcare.

Follow along with an expanded slideset at:
https://bit.ly/32RCX4N

Link to full program:
https://bit.ly/3G2GknK

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Shingles in the COVID-19 Era: Vaccination for Prevention of Complications—Audio Recap

support@deceraclinical.com (Dalilah Restrepo MD) — Tue, 23 Nov 2021 21:30:00 +0000

In this episode, Dalilah Restrepo, MD, discusses expert guidance on vaccination for the prevention of shingles complications in the COVID-19 era.

Contributor:

Dalilah Restrepo, MD
Infectious Diseases Specialist
Fountain Valley Hospital
Fountain Valley, California

Using a case study and the latest expert guidance, this podcast covers topics such as:

Expert guidance on maintenance of routine vaccination during the COVID-19 era
Common shingles complications in immunocompetent patients
Additional shingles complications in immunocompromised patients
Guidance on safe shingles vaccine delivery during the COVID-19 pandemic
CDC guidance catching up after RZV dosing delays

Content based on a CME program supported by an educational grant from GlaxoSmithKline.

Follow along with the downloadable slides at:
https://bit.ly/3r3AKx1

Link to full program:
https://bit.ly/3o4PB8N

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Key Decisions in HIV Care: Managing Suboptimal CD4+ Cell Count Increase Despite Suppressive ART

support@deceraclinical.com (William R. Short MD MPH AAHIVS) — Fri, 19 Nov 2021 21:00:00 +0000

In this episode, William R. Short, MD, MPH, AAHIVS, explores recommendations and data on strategies to address suboptimal CD4+ cell count response in people with HIV on suppressive ART.

Listen as he gives his perspectives on:

The consequences of suboptimal CD4+ cell count response
ART intensification
ART switch strategies with data from the SPIRAL study
Data on the addition of interleukin-2 from the SILCAAT and ESPIRIT studies
DHHS guideline recommendations

Presenter:
William R. Short, MD, MPH, AAHIVS
Associate Professor of Medicine
Division of Infectious Diseases
Department of Medicine
Perelman School of Medicine at the University of Pennsylvania
Philadelphia, Pennsylvania

Follow along with the slides at:
https://bit.ly/3DC2bkP

See the entire program at:
https://bit.ly/2TXTYWx

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Tackling Racial Disparities in HCV Care: Global Edition

Wed, 17 Nov 2021 21:45:00 +0000

In this episode, Prof Ashley Brown, BSc, MD, FRCP, and Ahmed M. Elsharkawy, PhD, FRCP(UK), discuss key racial inequities of care that lead to undertreatment for migrant populations and other racial minorities globally with or at risk for hepatitis C.

Topics include:

HCV Burden and Care Disparities in Specific Populations
Genotypes and Length of Infection in Ethnic Minorities
Primary Care Education and System-Related Barriers
Solutions to Overcome Barriers to HCV Care
First-hand Patient Stories

Prof Ashley Brown, BSc, MD, FRCP
Professor of Practice, Viral Hepatitis
Division of Metabolism, Digestion and Reproduction
Imperial College London
Consultant Hepatologist
Liver & Antiviral Unit
Imperial College Healthcare NHS Trust
London, United Kingdom

Ahmed M. Elsharkawy, PhD, FRCP(UK)
Consultant Hepatologist and
Honorary Senior Lecturer
Liver Unit and Biomedical Research Centre
University Hospitals Birmingham
University of Birmingham
Birmingham, United Kingdom

Content based on a CME program supported by educational grants provided by AbbVie; Gilead Sciences, Inc.; and Janssen Therapeutics, Division of Janssen Products, LP

To follow along, download the slides at:
https://bit.ly/36UDLVi

Link to full program:
https://bit.ly/3kKIb9a

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Emerging Insights on Adverse Events During ART and Implications for Treatment: Nephrotoxicity and Long-Acting Injectables

support@deceraclinical.com (Fidelia Bernice PharmD, Aadia I. Rana MD) — Tue, 16 Nov 2021 21:20:00 +0000

In this episode, Fidelia Bernice, PharmD, and Aadia I. Rana, MD, share insights on HIV ART safety and tolerability including recent data on nephrotoxicity and the use of NRTI-sparing regimens with discussion of the GEMINI-1 and -2 studies of DTG/3TC and the SWORD-1 and -2 studies of DTG/RPV, and safety with long-acting injectables with specific discussion of the ATLAS and FLAIR studies of LA CAB plus RPV and the CUSTOMIZE study.

Presenters:

Fidelia Bernice, PharmD
Clinical Pharmacy Specialist
Infectious Diseases
Department of Pharmacy
University of Maryland Medical Center
Baltimore, Maryland

Aadia I. Rana, MD
Associate Professor of Medicine
Division of Infectious Diseases
University of Alabama at Birmingham
1917 Clinic
Birmingham, Alabama

Content based on a CME program supported by independent educational grants fromJanssen Therapeutics, Division of Janssen Products, LP, and ViiV Healthcare.

Link to full program:
https://bit.ly/3ydMtcL

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Shingles in the COVID-19 Era: Shingles Vaccination Guidelines—Audio Recap

support@deceraclinical.com (Tracy Zivin-Tutela MD) — Thu, 11 Nov 2021 22:30:00 +0000

In this episode, Tracy Zivin-Tutela, MD, discusses expert guidance on vaccination against shingles.

Tracy Zivin-Tutela, MD
Infectious Diseases Specialist
Department of Infectious Diseases
Fountain Valley Regional Hospital
Los Alamitos Medical Center
Fountain Valley, California

Using a case study and the latest expert guidance, this podcast covers topics such as:

Counseling patients on benefits and efficacy of vaccination against shingles
Vaccine safety
Vaccination guidelines for adults with or without previous vaccination with zoster vaccine live or recalled childhood chickenpox
Administration of vaccination with consideration for other routine vaccines for flu, pneumonia, COVID-19

Content based on a CME program supported by an educational grant from GlaxoSmithKline

Follow along with the downloadable slides at:
https://bit.ly/3kunxJr

Link to full program:
https://bit.ly/3o4PB8N

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Key Decisions in HIV Care: Switching to a 2-Drug Single-Tablet Regimen

support@deceraclinical.com (William R. Short MD MPH AAHIVS) — Wed, 10 Nov 2021 22:30:00 +0000

In this episode, William R. Short, MD, MPH, AAHIVS, explores recommendations and data on switching to 2-drug single-tablet ART regimens.

Listen as he gives his perspectives on:

Indications for the available 2-drug single-tablet regimens: DTG/RPV and DTG/3TC
The SWORD-1 and SWORD-2 studies evaluating switching to DTG/RPV in virologically suppressed patients
Real-world experience with switching to DTG/RPV from the OPERA study
The TANGO study evaluating switching to DTG/3TC from a stable TAF-based ART regimen
The SALSA study evaluating switching to DTG/3TC from any stable 3-drug ART regimen

Follow along with the slides at:
https://bit.ly/3n0Z8wU

See the entire program at:
https://bit.ly/2TXTYWx

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Lessons From Lockdown: Perspectives on Hepatitis C Care in the US and Australia—Audio Recap

Wed, 10 Nov 2021 21:30:00 +0000

In this episode, Gregory Dore, MBBS, PhD, FRACP, MPH, and Stacey Trooskin, MD, PhD, MPH, share lessons learned in the care of patients with HCV infection during the COVID-19 pandemic, including:

Telehealth
Treatment of PWID
TEMPO pilot study
MINMON study

Presenters:

Gregory Dore, MBBS, PhD, FRACP, MPH
Professor, Head
Viral Hepatitis Clinical Research Program
Kirby Institute
University of New South Wales
Infectious Diseases Physician
St. Vincent's Hospital
Sydney, Australia

Stacey Trooskin, MD, PhD, MPH
Chief Medical Officer
Philadelphia FIGHT Community Health Centers
Faculty
Division of Infectious Diseases
Perelman School of Medicine
University of Pennsylvania
Philadelphia, Pennsylvania

Follow along with the slides at:
https://bit.ly/3naBUVj

Link to full program:
https://bit.ly/3F5bxG8

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Should We Screen Patients With HIV for NAFLD/NASH?

support@deceraclinical.com (Giada Sebastiani MD) — Wed, 10 Nov 2021 17:00:00 +0000

In this episode, hepatologist Giada Sebastiani, MD, discusses why the presence of obesity, metabolic syndrome, persistent elevation of ALT, or exposure to dideoxynucleoside analogues can trigger an evaluation for NAFLD and NASH, particularly in our aging population of patients with HIV with topics including:

Metabolic factors
HIV-related factors
Which patients with HIV are at risk

Presenter:

Content based on an online CME program supported by an educational grant from Theratechnologies Inc.

Link to full program:
https://bit.ly/3BYoXBP

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Key Decisions in HIV Care: ART in Pregnancy

Mon, 8 Nov 2021 22:00:00 +0000

In this episode from the series “Key Decisions in HIV Care,” Milena Murray, PharmD, MSc, BCIDP, AAHIVP, and Jonah Musa, MBBS, MSCI, PhD, discuss important considerations for ART use in pregnancy, including DHHS and WHO guideline recommendations and data supporting recommended ART regimen options in pregnancy from IMPAACT 2010, Tsepamo, and DoLPHIN-2. They also discuss pharmacokinetic considerations and drug–drug interactions. Following their dialogue, the faculty field questions from healthcare professionals.

Presenters:

Milena Murray, PharmD, MSc, BCIDP, AAHIVP
Associate Professor
Pharmacy Practice
Midwestern University College of Pharmacy, Downers Grove Campus
Downers Grove, Illinois
HIV/ID Clinical Pharmacist
Northwestern Memorial Hospital
Chicago, Illinois

Jonah Musa, MBBS, MSCI, PhD
Professor, Obstetrics and Gynecology
University of Jos
Honorary Consultant Obstetrician and Gynecologist
Jos University Teaching Hospital
Jos, Nigeria

Content based on an online CME program supported by educational grants from Gilead Sciences, Inc.; Janssen Therapeutics, Division of Janssen Products, LP; and ViiV Healthcare.

Follow along with the slides at:
https://bit.ly/3GRxpGQ

Link to full program:
https://bit.ly/2TXTYWx

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Key COVID-19 Studies Influencing My Practice Following IDWeek 2021—Audio Recap

support@deceraclinical.com (Renslow Sherer MD) — Fri, 29 Oct 2021 20:30:00 +0000

In this episode, Renslow Sherer, MD, discusses new COVID-19 data from IDWeek 2021, including:

Prevention of COVID-19
- ChAdOx1 nCoV-19
- Ad26.COV2.S
- Tixagevimab plus cilgavimab
Outpatients with COVID-19
- Remdesivir IV
- Molnupiravir
Hospitalized patients with COVID-19
- Baricitinib
- Lenzilumab
- Casirivimab plus imdevimab
Long-term COVID-19 outcomes
- Sustained recovery

Presenter:

Link to full program and downloadable slides:
https://bit.ly/3BCHF2E

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Racial Disparities in COVID-19: Causes, Consequences, and Clinical Strategies—Audio Recap

support@deceraclinical.com (Oni Blackstock MD MHS, Nina T Harawa PhD MPH) — Fri, 29 Oct 2021 20:15:00 +0000

In this episode, Oni Blackstock, MD, MHS, and Nina T. Harawa, PhD, MPH, discuss racial disparities in COVID-19 outcomes, including:

Background on healthcare inequities among BIPOC
COVID-19 racial disparities and the healthcare inequities driving them
Overcoming barriers to optimal COVID-19 care among BIPOC
Addressing concerns about COVID-19 vaccination
Motivational interviewing principles and the brief negotiated interview to earn trust and increase vaccine acceptance

Presenters:

Oni Blackstock, MD, MHS
Founder and Executive Director
Health Justice
New York, New York

Nina T. Harawa, PhD, MPH
Professor of Medicine and Epidemiology
UCLA David Geffen School of Medicine
Charles R. Drew University of Medicine and Science
Policy Core Director
UCLA Center for HIV Identification, Prevention, and Treatment Services (CHIPTS)
Los Angeles, California

Link to full program and downloadable slides:
https://bit.ly/3blGA3R

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The Promise of Individualized HIV Prevention: Future Formulations and Dosing Intervals for Long-Acting PrEP

support@deceraclinical.com (Decera Clinical Education) — Thu, 21 Oct 2021 19:20:00 +0000

In this episode, Nicholas Chamberlain, MD, provides an overview of the different antiretroviral drug formulations and dosing strategies in various stages of clinical development for long-acting HIV PrEP—advances that collectively offer the potential for highly individualized approaches to HIV biomedical prevention.

Presenter:

Nicholas Chamberlain, MD
Medical Director
AHF Healthcare Center – Atlanta Midtown
Department of Medicine
AIDS Healthcare Foundation
Atlanta, Georgia

Content based on an online CME program supported by an independent educational grant from Gilead Sciences, Inc.

Link to full program:
https://bit.ly/3AFvsZY

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A Long Journey to HCV Cure: Conversations Between Patient and Physician #1

support@deceraclinical.com (Stacey Trooskin MD PhD MPH) — Tue, 19 Oct 2021 20:00:00 +0000

In episode 1 of an ongoing series of conversations between a physician and patient, Stacey Trooskin, MD, PhD, MPH, and patient advocate Brother Dan Palmer discuss approaches to improve access to HCV therapy. The conversation focuses on how barriers to care affected Dan’s health after his hepatitis C diagnosis and the strategies he employed to overcome them.

Presenter:

Content based on an online CME program supported by independent educational grants from AbbVie and Gilead Sciences.

Link to full program:
https://bit.ly/3lSkSui

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New COVID-19 Data: A Case for Optimism?

support@deceraclinical.com (Renslow Sherer MD, Paul E. Sax MD) — Thu, 14 Oct 2021 20:00:00 +0000

In this podcast episode, Paul E. Sax, MD, and Renslow Sherer, MD, discuss the clinical significance of new data on the prevention and treatment of COVID-19, including:

COVID-19 in immunocompromised hosts
Prime-Boost Strategy for COVID-19 vaccination
COVID-19 surge effects
Monoclonal antibody therapy for prevention and treatment
Remdesivir update
Repurposed drug, fluvoxamine
What does the future of the pandemic look like?

Presenters:

Paul E. Sax, MD
Clinical Director
HIV Program and Division of Infectious Diseases
Brigham and Women's Hospital
Professor of Medicine
Harvard Medical School
Boston, Massachusetts

Link to full program, including downloadable slidesets:
https://bit.ly/3zVTwYW

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Key Decisions in HIV Care: What to Do About Missed CAB + RPV LA Injections?

support@deceraclinical.com (Milena Murray PharmD MSc BCIDP AAHIVP) — Wed, 13 Oct 2021 20:15:00 +0000

In this episode, Milena Murray, PharmD, MSc, BCIDP, AAHIVP, explores recommendations and data to support the management of missed CAB plus RPV injections.

Listen as she gives her perspectives on:

Prescribing information recommendations for managing missed injections of CAB plus RPV
Pharmacokinetic modeling data to support management strategies for missed injections
Data from the ATLAS and FLAIR studies on missed injections and patient outcomes

Presenter:

Follow along with the slides at:
https://bit.ly/30nJfaZ

See the entire program at:
https://bit.ly/2TXTYWx

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Key Decisions in HIV Care: Considerations for Maternal Weight Gain

support@deceraclinical.com (Milena Murray PharmD MSc BCIDP AAHIVP) — Tue, 12 Oct 2021 20:10:00 +0000

In this episode, Milena Murray, PharmD, MSc, BCIDP, AAHIVP, explores recommendations and data on maternal weight gain associated with ART use in pregnancy.

Listen as she gives her perspectives on:

IMPAACT 2010 data on maternal weight gain with DTG + FTC/TAF vs DTG + FTC/TDF vs EFV/FTC/TDF
SMARTT study data on gestational weight gain by ART class
Tsepamo Surveillance study data on maternal weight and birth outcomes among women receiving ART, as well as weight outcomes with DTG vs EFV
DHHS Perinatal Guideline recommendations on dolutegravir and maternal weight gain

Presenter:

Milena Murray, PharmD, MSc, BCIDP, AAHIVP
Associate Professor
Pharmacy Practice
Midwestern University College of Pharmacy
Downers Grove Campus
HIV/ID Clinical Pharmacist
Northwestern Memorial Hospital
Chicago, Illinois

Follow along with the slides at:
https://bit.ly/3DusMQk

See the entire program at:
https://bit.ly/2TXTYWx

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Key HIV Studies Influencing My Practice Following IDWeek 2021 – Audio Recap

support@deceraclinical.com (Darcy Wooten MD) — Mon, 11 Oct 2021 20:45:00 +0000

In this episode, Darcy Wooten, MD, discusses new HIV data from IDWeek 2021, including:

A rapid test-and-treat program to start DTG/3TC in patients newly diagnosed with HIV (STAT)
Efficacy when switching from 3-drug to 4-drug TAF-based regimens to DTG/3TC (TANGO)
Virologic outcomes with 2-drug vs 3-drug ART regimens (Trio Health HIV Network Study)
Metabolic complications in treatment-naive patients (Study 1489 and Study 1490)
Resistance analysis of an investigational agent, lenacapavir (CALIBRATE)
The Positive Perspectives Survey to evaluate the U=U Educational Campaign in North American patients

Presenter:

Darcy Wooten, MD
Associate Professor of Medicine
Division of Infectious Diseases and Global Public Health
Department of Medicine
University of California, San Diego
San Diego, California

Link to full program:
https://bit.ly/3BCHF2E

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Audio Recap: Timely Treatment for COVID-19

support@deceraclinical.com (Lynora Saxinger MD FRCPC CTropMed, Lynora Saxinger) — Mon, 11 Oct 2021 20:00:00 +0000

During this episode, Lynora Saxinger, MD, FRCPC, CTropMed, updates listeners on the latest Emergency Use Authorizations and guideline recommendations for optimal clinical management of COVID-19. Gain practical insights on patient identification, risk stratification, and treatment.

Key points include:

Treatment of COVID-19 can be broken into antiviral and immune-modulating therapies
Each agent should be used at the correct disease stage to maximize benefit
Antiviral medications and mAbs show the greatest promise early during COVID-19, before the host immune response is mounted
Passive immunization with mAbs can prevent infection and severe disease—and mortality—if given early to hospitalized persons
Operational challenges to using these medications exist, but given the epidemic of unvaccinated persons, these treatments become increasingly relevant to reduce burden on healthcare systems

Presenter:

Lynora Saxinger, MD, FRCPC, CTropMed
Cochair, Scientific Advisory Group
Alberta COVID-19 Emergency Coordination Centre
Associate Professor
Division of Infectious Diseases
Department of Medicine
University of Alberta
Edmonton, Alberta, Canada

Content based on an online CME program supported by an educational grant from Gilead Sciences, Inc.

Follow along with the slides at:
https://bit.ly/3BxQKtD

Link to full program:
https://bit.ly/3BwzdlC

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Key Decisions in HIV Care: Rapid Initiation of ART

support@deceraclinical.com (Jason Halperin MD MPH, Jürgen K. Rockstroh MD) — Wed, 29 Sep 2021 21:00:00 +0000

In this episode from the series “Key Decisions in HIV Care,” Jason Halperin, MD, MPH, and Jürgen K. Rockstroh, MD, discuss important considerations in the rapid initiation of ART, including guideline recommendations and data supporting recommended ART regimen options for rapid initiation and emerging data for the 2-drug regimen dolutegravir/lamivudine for rapid start from the STAT study. Following their dialogue, the faculty field questions from healthcare professionals.

Presenters:
Jason Halperin, MD, MPH
Assistant Professor of Medicine
Department of Infectious Diseases
Tulane University
Infectious Disease Physician
CrescentCare
New Orleans, Louisiana

Jürgen K. Rockstroh, MD
Professor of Medicine
University Hospital Bonn
Department of Medicine I
Bonn, Germany

Content based on an online CME program supported by educational grants from Gilead Sciences, Inc.; Janssen Therapeutics, Division of Janssen Products, LP; and ViiV Healthcare.

Follow along with the slides at:
https://bit.ly/2XWPuBi

Link to full program:
https://bit.ly/2TXTYWx

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Key Decisions in HIV Care: Tenofovir Alafenamide in Pregnancy

support@deceraclinical.com (Milena Murray PharmD MSc BCIDP AAHIVP) — Wed, 29 Sep 2021 20:15:00 +0000

In this episode, Milena Murray, PharmD, MSc, BCIDP, AAHIVP, explores the data to support the use of tenofovir alafenamide in pregnancy.

Listen as she gives her perspectives on:

DHHS guideline recommendations for the use of TAF in pregnancy
Pharmacokinetic data to support adequate TAF concentrations throughout pregnancy
Available antiretroviral pregnancy registry information on the use of TAF in pregnancy
Data from the IMPAACT 2010 study to support the use of a TAF-containing regimen in pregnancy

Presenter:

Follow along with the slides at:
https://bit.ly/3ofTHLr

Link to full program:
https://bit.ly/2TXTYWx

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Shingles in the COVID-19 Era: Risk Factors and Complications—Audio Recap

support@deceraclinical.com (Tracy Zivin-Tutela MD) — Fri, 24 Sep 2021 19:15:00 +0000

In this episode, Tracy Zivin-Tutela, MD, discusses factors that put your patients at risk for shingles and its complications.

Tracy Zivin-Tutela, MD
Infectious Diseases Specialist
Department of Infectious Diseases
Fountain Valley Regional Hospital
Los Alamitos Medical Center
Fountain Valley, California

Using a case study and the latest data, this podcast covers topics such as:

Pathophysiology and epidemiology
Disease burden and potential complications in older patients, including postherpetic neuralgia
Risk factors, including age, immunosenescence, chronic diseases, unvaccinated status

Content based on a CME program supported by an educational grant from GlaxoSmithKline

Follow along with the downloadable slides at:
https://bit.ly/3ENbcbP

Link to full program:
https://bit.ly/3o4PB8N

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Key Decisions in HIV Care: Considering Rapid ART in a Patient With Opioid Use Disorder

support@deceraclinical.com (Jason Halperin MD MPH) — Thu, 23 Sep 2021 20:20:00 +0000

In this episode, Jason Halperin, MD, MPH, explores the data to support rapid ART initiation in patients with OUD.

Listen as he gives his perspectives on:

DHHS guidelines for rapid initiation of ART and specific recommendations for patients with substance use disorders
SAMSHA recommendations for the treatment of OUD
Medications that are recommended for the treatment of OUD, including drug–drug interaction considerations with ART
Data to support the treatment of OUD to improve HIV viral suppression rates

In addition, hear his patient’s perspective on the importance of receiving treatment for his OUD and HIV together.

Presenter:

Jason Halperin, MD, MPH
Assistant Professor of Medicine
Department of Infectious Diseases
Tulane University
Infectious Disease Physician
CrescentCare
New Orleans, Louisiana

Follow along with the slides:
https://bit.ly/3kE5Wzq

See the entire program at:
https://bit.ly/2TXTYWx

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Key Decisions in HIV Care: Initiating Timely ART in a Newly Diagnosed Adolescent

support@deceraclinical.com (Jason Halperin MD MPH) — Thu, 23 Sep 2021 20:20:00 +0000

In this episode, Jason Halperin, MD, MPH, explores the data to support rapid ART initiation in adolescent patients.

Listen as he gives his perspectives on:

DHHS and IAS-USA guidelines for rapid initiation and specific recommendations for adolescents and young adults
CrescentCare data comparing the virologic outcomes for patients 18-24 years of age compared with those aged 25 years or older
Data to suggest that rapid ART upholds equity

In addition, hear his patient’s perspective on the importance of rapid initiation of ART to prevent transmission to others and the burden it lifted for him.

Presenter:

Jason Halperin, MD, MPH
Assistant Professor of Medicine
Department of Infectious Diseases
Tulane University
Infectious Disease Physician
CrescentCare
New Orleans, Louisiana

Follow along with the slides at:
https://bit.ly/39xL5r0

See the entire program at:
https://bit.ly/2TXTYWx

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Emerging Long-Acting PrEP Options

support@deceraclinical.com (Decera Clinical Education) — Thu, 16 Sep 2021 20:30:00 +0000

In this episode, Colleen Kelley, MD, MPH, discusseskey features and available safety and efficacy data on investigational long-acting HIV pre-exposure prophylaxis strategies that are in late stages of clinical development.

Presenter:

Colleen Kelley, MD, MPH
Atlanta, Georgia

Colleen Kelley, MD, MPH, has disclosed that she has received funds for research support from Gilead Sciences, Moderna, Novavax, and ViiV Healthcare.

Content based on an online CME program supported by an independent educational grant from Gilead Sciences, Inc.

Link to full program: https://bit.ly/3AFvsZY

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Contemporary Management of HIV 2021: New Data From IAS 2021—Audio Recap, Part 2

support@deceraclinical.com (Eric S Daar MD, Shobha Swaminathan MD) — Tue, 14 Sep 2021 21:00:00 +0000

In this second of 2 episodes, Shobha Swaminathan, MD, and Eric S. Daar, MD, review key data influencing their practice following the IAS 2021 Conference, including data on investigational antiretroviral agents, lenacapavir and islatravir, and alternative dosing of BPaL for MDR-TB.

This episode includes discussion of:

An extension of FLAIR, demonstrating virologic efficacy and safety of long-acting CAB plus RPV at Week 124
A Week 26 safety and efficacy analysis of CAPELLA, a study of lenacapavir in heavily treatment–experienced PWH
CALIBRATE, a study of the safety and efficacy of lenacapavir in treatment-naive PWH
A Week 96 safety analysis of Protocol 011, evaluating islatravir plus DOR in treatment-naive patients
A Week 24 safety and pharmacokinetic analysis of Protocol 016, evaluating oral islatravir once monthly for PrEP
ZeNix, a phase III trial of pretomanid, bedaquiline, and linezolid (BPaL) in patients with highly resistant TB

Presenters:

Eric S. Daar, MD
Chief, Division of HIV Medicine
Harbor-UCLA Medical Center
Professor of Medicine
David Geffen School of Medicine at UCLA
Los Angeles, California

Shobha Swaminathan, MD
Associate Professor
Division of Infectious Diseases
Department of Medicine
Rutgers New Jersey Medical School
Newark, New Jersey

Follow along with the slides at:
https://bit.ly/3hvRN5b

Content based on an online CME program supported by an educational grant from ViiV Healthcare.

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

The Monoclonal Antibodies Strike Back: New Data on Their Use in COVID-19

support@deceraclinical.com (Decera Clinical Education) — Tue, 14 Sep 2021 14:00:00 +0000

In this podcast episode, Sharon R. Lewin, AO, FRACP, PhD, FAHMS, and Arthur Kim, MD, discuss data on the potential use of monoclonal antibodies (mAb) for the prevention and treatment of COVID-19, including:

Rationale for use of mAb
Potential for resistance to mAb
Single vs combination therapy with mAb
Challenges in implementation of mAb as treatment or prevention
Bamlanivimab
Sotrovimab
Casirivimab plus imdevimab

Link to full program, including downloadable slidesets: https://bit.ly/3zVTwYW

Presenters:

Sharon R. Lewin, AO, FRACP, PhD, FAHMS
Director, The Peter Doherty Institute for Infection and Immunity
Professor of Infectious Diseases
Faculty Medicine Dentistry and Health Sciences
University of Melbourne and Royal Melbourne Hospital
Consultant Infectious Diseases Physician
Department of Infectious Diseases
Royal Melbourne Hospital and Alfred Hospital
Melbourne, Australia

Arthur Kim, MD
Associate Professor
Department of Medicine
Harvard Medical School
Director, Viral Hepatitis Clinic
Division of Infectious Diseases
Massachusetts General Hospital
Boston, Massachusetts

Sharon R. Lewin, AO, FRACP, PhD, FAHMS, has disclosed that she has received consulting fees from AbbVie, Gilead Sciences, and ViiV Healthcare; funds for research support from Leidos; and other financial or material support from Gilead Sciences, Merck, and ViiV Healthcare.

Arthur Kim, MD, has disclosed that he has served on the drug and safety monitoring board for Kintor.

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Contemporary Management of HIV 2021: New Data From IAS 2021—Audio Recap, Part 1

support@deceraclinical.com (Shobha Swaminathan MD, Eric S Daar MD) — Wed, 8 Sep 2021 20:30:00 +0000

In this first of 2 episodes, Shobha Swaminathan, MD, and Eric S. Daar, MD, review key data influencing their practice following the IAS 2021 Conference, including results from studies on HIV and COVID-19 outcomes; virologic and metabolic outcomes of DTG/3TC; long-acting CAB plus RPV for ART in treatment-naive PWH.

This episode includes discussion of:

A Global Clinical Platform that evaluated outcomes of PWH hospitalized with COVID-19
A post hoc analysis of TANGO, evaluating the virologic and metabolic outcomes when switching to DTG/3TC vs continued 3- or 4-drug TAF-based regimens
A Week 48 analysis of SALSA, demonstrating virologic efficacy and favorable safety profile of switching to DTG/3TC vs continuing a 3-drug ART regimen

Presenters:

Eric S. Daar, MD
Chief, Division of HIV Medicine
Harbor-UCLA Medical Center
Professor of Medicine
David Geffen School of Medicine at UCLA
Los Angeles, California

Shobha Swaminathan, MD
Associate Professor
Division of Infectious Diseases
Department of Medicine
Rutgers New Jersey Medical School
Newark, New Jersey

Follow along with the slides at:
https://bit.ly/3hvRN5b

Content based on an online CME program supported by an educational grant from ViiV Healthcare.

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Contemporary Management of HIV 2021: Heavily Treatment–Experienced Patients—Audio Recap, Part 3

support@deceraclinical.com (Geeta Gupta MD) — Tue, 7 Sep 2021 22:15:00 +0000

In this series of 3 episodes, Geeta Gupta, MD, discusses strategies for optimizing ART in heavily treatment–experienced patients with HIV, including management of virologic failure and switching ART in virologically suppressed patients with underlying resistance. The 3 episodes will include analyses from:

BENCHMRK, which demonstrated that the number of active drugs predicts outcomes in treatment-experienced patients
TMB-301, a study that added the monoclonal antibody ibalizumab in pretreated patients with multidrug-resistant HIV and demonstrated significant decreases in HIV-1 RNA
BRIGHTE, which showed that the addition of fostemsavir in heavily treatment–experienced patients with HIV led to a significant decrease in HIV-1 RNA
VIKING-3, a study that demonstrated the addition of DTG dosed BID in INI-resistant patients was effective in decreasing HIV-1 RNA
SWITCHMRK, a study that showed underlying resistance matters when deciding to switch regimens in a treatment-experienced, virologically suppressed patient, especially when switching to a regimen with a low barrier to resistance
DAWNING, a study that demonstrated that DTG, when added to 2 NRTIs, was superior to RTV-boosted LPV in patients with virologic failure on an NNRTI plus 2 NRTIs
BRAAVE, which evaluated safety and efficacy of switching to BIC/FTC/TAF in Black patients virologically suppressed on 2 NRTIs plus a third agent

In addition, Dr. Gupta reviews current DHHS ART guideline recommendations related to managing virologic failure, including drug resistance testing and drug selection, as well as switching recommendations in patients with viral suppression and underlying drug resistance.

Presenter:

Geeta Gupta, MD
Professor
Director, AIDS Education and Training Center
University of California, Irvine
Orange, California

Follow along with the slides at:
https://bit.ly/3zxKBfL

Content based on an online CME program supported by an educational grant from ViiV Healthcare.

Link to full program:
https://bit.ly/3ux6FF8

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Tackling Racial Disparities in HBV Care

Fri, 3 Sep 2021 20:30:00 +0000

In this episode, Mindie H. Nguyen, MD, MAS, AGAF, FAASLD, and Lewis R. Roberts, MB ChB, PhD, examine the HBV burden and care disparities in specific populations, including Asian Americans and foreign-born immigrants, and strategies to address barriers to care.

Presenters:

Mindie H. Nguyen, MD, MAS, AGAF, FAASLD
Professor of Medicine
Department of Gastroenterology and Hepatology
Stanford University Medical Center
Palo Alto, California

Lewis R. Roberts, MB ChB, PhD
Professor of Medicine and Consultant
Division of Gastroenterology and Hepatology
Mayo Clinic
Rochester, Minnesota

Content based on a CME program supported by educational grants provided by AbbVie; Gilead Sciences, Inc.; and Janssen Therapeutics, Division of Janssen Products, LP

To follow along, download the slides at:
https://bit.ly/3gWStjZ

Link to full program:
https://bit.ly/3kKIb9a

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Contemporary Management of HIV 2021: Heavily Treatment–Experienced Patients—Audio Recap Part 2

support@deceraclinical.com (Geeta Gupta MD) — Thu, 2 Sep 2021 20:30:00 +0000

BENCHMRK, which demonstrated that the number of active drugs predicts outcomes in treatment-experienced patients
TMB-301, a study that added the monoclonal antibody ibalizumab in pretreated patients with multidrug-resistant HIV and demonstrated significant decreases in HIV-1 RNA
BRIGHTE, which showed that the addition of fostemsavir in heavily treatment–experienced patients with HIV led to a significant decrease in HIV-1 RNA
VIKING-3, a study that demonstrated the addition of DTG dosed BID in INI-resistant patients was effective in decreasing HIV-1 RNA
SWITCHMRK, a study that showed underlying resistance matters when deciding to switch regimens in a treatment-experienced, virologically suppressed patient, especially when switching to a regimen with a low barrier to resistance
DAWNING, a study that demonstrated that DTG, when added to 2 NRTIs, was superior to RTV-boosted LPV in patients with virologic failure on an NNRTI plus 2 NRTIs
BRAAVE, which evaluated safety and efficacy of switching to BIC/FTC/TAF in Black patients virologically suppressed on 2 NRTIs plus a third agent

Presenter:

Geeta Gupta, MD
Professor
Director, AIDS Education and Training Center
University of California, Irvine
Orange, California

Follow along with the slides at:
https://bit.ly/3zxKBfL

Content based on an online CME program supported by an educational grant from ViiV Healthcare.

Link to full program:
https://bit.ly/3ux6FF8

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Contemporary Management of HIV 2021: Heavily Treatment–Experienced Patients—Audio Recap, Part 1

support@deceraclinical.com (Geeta Gupta MD) — Wed, 1 Sep 2021 20:20:00 +0000

BENCHMRK, which demonstrated that the number of active drugs predicts outcomes in treatment-experienced patients
TMB-301, a study that added the monoclonal antibody ibalizumab in pretreated patients with multidrug-resistant HIV and demonstrated significant decreases in HIV-1 RNA
BRIGHTE, which showed that the addition of fostemsavir in heavily treatment–experienced patients with HIV led to a significant decrease in HIV-1 RNA
VIKING-3, a study that demonstrated the addition of DTG dosed BID in INI-resistant patients was effective in decreasing HIV-1 RNA
SWITCHMRK, a study that showed underlying resistance matters when deciding to switch regimens in a treatment-experienced, virologically suppressed patient, especially when switching to a regimen with a low barrier to resistance
DAWNING, a study that demonstrated that DTG, when added to 2 NRTIs, was superior to RTV-boosted LPV in patients with virologic failure on an NNRTI plus 2 NRTIs
BRAAVE, which evaluated safety and efficacy of switching to BIC/FTC/TAF in Black patients virologically suppressed on 2 NRTIs plus a third agent

Presenter:

Geeta Gupta, MD
Professor
Director, AIDS Education and Training Center
University of California, Irvine
Orange, California

Follow along with the slides at:
https://bit.ly/3zxKBfL

Content based on an online CME program supported by an educational grant from ViiV Healthcare.

Link to full program:
https://bit.ly/3ux6FF8

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Key Decisions in HIV Care: Weight Gain in ART

support@deceraclinical.com (Joseph J Eron MD) — Mon, 30 Aug 2021 20:30:00 +0000

In this episode, Joseph J. Eron, Jr., MD, explores whether weight gain should or should not be a factor in determining initial therapy.

Listen as he gives his perspectives on:

Weight gain following ART initiation by ARV class and ARV drug
Results of the ADVANCE and GEMINI-1 and -2 studies, with exploration of weight, risk of CVD and diabetes
BMI changes in PWH
DHHS and IAS-USA guidelines for initial therapy

Presenter:

Joseph J. Eron, MD
Professor of Medicine and Epidemiology
University of North Carolina
School of Medicine
Director, AIDS Clinical Trials Unit
University of North Carolina
Chapel Hill, North Carolina

Follow along with the slides at:
https://bit.ly/3DyLgA3

See the entire program at:
https://bit.ly/2TXTYWx

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Contemporary Management of HIV 2021: Modifying ART in Virologically Suppressed Patients

support@deceraclinical.com (David Malebranche) — Wed, 25 Aug 2021 20:30:00 +0000

In this episode, David Malebranche, MD, MPH, discusses modifying ART in virologically suppressed patients, including switching ART in a patient with daily pill fatigue, switching ART to avoid comorbidities and simplifying ART in the context of known multidrug resistance. The overview will include analyses from:

The ATLAS and FLAIR studies in which long-acting intramuscular CAB + RPV was initiated after initial virologic suppression with oral therapy
D:A:D study data that found cumulative use of RTV-boosted DRV, but not RTV-boosted ATV, was independently associated with a small but progressively increasing risk of CVD events
The SWORD-1 and -2 evaluating the switch to DTG + RPV vs continuation of baseline ART in virologically suppressed adults
The TANGO study that compared switching to DTG/3TC vs continuing a TAF-based 3-drug regimen
The DAWNING study that showed favorable outcomes for treatment-experienced patients switched to DTG containing regimens with an M184V mutation, whether the regimen contained emtricitabine or lamivudine or not
Study 380-4030 that showed noninferiority in maintenance of viral suppression when switching to BIC/FTC/TAF from DTG + FTC/(TAF or TDF)
BRAAVE 2020 that evaluated the impact of baseline resistance on outcomes following a switch to BIC/FTC/TAF in Black PWH

In addition, Dr. Malebranche reviews current recommendations by the DHHS regarding considerations when switching regimens in virologically suppressed patients and switching regimens in patients with viral suppression and drug resistance.

Presenter:

David J. Malebranche, MD, MPH
Internal Medicine Physician
HIV/Sexual Health Specialist
Clinician, AIDS Healthcare Foundation (AHF) Medical Clinic
Atlanta, Georgia

Follow along with the slides at:
https://bit.ly/3kseOqk

Content based on an online CME program supported by an educational grant from ViiV Healthcare.

Link to full program:
https://bit.ly/3ux6FF8

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Contemporary Management of HIV 2021: Emerging Paradigms in ART

support@deceraclinical.com (Paul E Sax MD) — Wed, 25 Aug 2021 20:30:00 +0000

In this episode, Paul E. Sax, MD, discusses emerging drug therapies and treatment options for patients with HIV, including rapid initiation of ART, long-acting ART, and 2-drug ART regimens. The overview will include analyses from:

The RAPID ART program in San Francisco, where same-day initiation of ART led to faster HIV-1 RNA suppression that was maintained at greater than 92% during a 3-year period
The DIAMOND study analyzing virologic efficacy and safety at 48 weeks after initiating DRV/COBI/FTC/TAF within 24 hours of HIV infection diagnosis
A rapid ART start program in young PWH in New Orleans that demonstrated achievement of viral suppression in fewer than 30 days and no discontinuations due to adverse events
The ATLAS (including ATLAS-2M) and FLAIR studies that demonstrated efficacy and safety of long-acting injectable CAB plus RPV
SWORD-1 and SWORD-2 that demonstrated switching to a 2-drug regimen of DTG plus RPV in virologically suppressed adults was safe and effective
GEMINI-1 and GEMINI-2 that demonstrated noninferiority of DTG plus 3TC compared with DTG plus FTC/TDF
TANGO that demonstrated safety and efficacy of switching to DTG/3TC in virologically suppressed adults receiving a TAF-based regimen

In addition, Dr. Sax reviews current recommendations by the DHHS, WHO, and IAS-USA regarding these emerging therapies and treatment paradigms.

Presenter:

Paul E. Sax, MD
Clinical Director
HIV Program and Division of Infectious Diseases
Brigham and Women’s Hospital
Professor of Medicine
Harvard Medical School
Boston, Massachusetts

Follow along with the slides at:
https://bit.ly/3zdPwm2

Content based on an online CME program supported by an educational grant from ViiV Healthcare.

Link to full program:
https://bit.ly/3ux6FF8

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Conference Conversations: Pharmacist Perspectives From IAS 2021

support@deceraclinical.com (Jennifer Cocohoba PharmD, Jason Schafer PharmD) — Mon, 23 Aug 2021 20:30:00 +0000

In this episode, Jennifer Cocohoba, PharmD, and Jason Schafer, PharmD, MPH, discuss key studies from IAS 2021 that will influence the role of the pharmacist in the treatment and prevention of HIV. Their discussion includes analyses of:

The 144-week analysis of the TANGO study, showing high rates of virologic suppression of patients switched from a TAF-containing regimen to DTG plus 3TC
The 144-week analysis of the TANGO study, showing high rates of virologic suppression of patients switched from a TAF-containing regimen to DTG plus 3TC
An extension of the FLAIR study, evaluating efficacy and safety of long-acting CAB plus RPV in treatment-naive patients
The CUSTOMIZE study, an implementation effectiveness study that evaluated the feasibility of implementing provision of long-acting CAB plus RPV in the clinic setting
The HPTN 084 study of PrEP using CAB vs TDF plus FTC in sexually active cisgender women
The CALIBRATE and CAPELLA studies of long-acting lenacapavir in treatment-naive and treatment-experienced patients, respectively

In addition, Drs. Cocohoba and Schafer discuss key considerations of these medications, including cost and acquisition logistics.

Presenters:

Jennifer Cocohoba, PharmD
Professor
Department of Clinical Pharmacy
University of California, San Francisco
San Francisco, California

Jason Schafer, PharmD
Professor and Vice Chair
Jefferson College of Pharmacy
Thomas Jefferson University
Philadelphia, Pennsylvania

Content based on conference coverage of IAS 2021 with educational rant support from Gilead Sciences, Inc.; Janssen Therapeutics, Division of Janssen Products, LP; Merck Sharp & Dohme Corp.; and ViiV Healthcare.

Link to full program:
https://bit.ly/3z8SBnC

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Key Studies Influencing My Practice Following IAS 2021—Audio Recap

support@deceraclinical.com (Decera Clinical Education) — Thu, 19 Aug 2021 20:30:00 +0000

In this episode, Babafemi Taiwo, MBBS, discusses new HIV data from IAS 2021, including:

WHO Global Clinical Platform: COVID-19 outcomes in PWH
2-drug regimen of DTG/3TC: efficacy, metabolic outcomes (TANGO)
Investigational antiretroviral use
- CAB LA + RPV LA in treatment-naive PWH (FLAIR)
Investigational antiretroviral agents
- LEN (CAPELLA, CALIBRATE)
- ISL (P011, P016)
Alternative BPaL dosing in treatment of drug-resistant TB (ZeNix)

Babafemi Taiwo, MBBS
Gene Stollerman Professor of Medicine
Chief, Division of Infectious Diseases
Northwestern University Feinberg School of Medicine
Chicago, Illinois

Content based on a CME program supported by educational grants from Gilead Sciences, Inc.; Janssen Therapeutics, Division of Janssen Products, LP.; Merck Sharp & Dohme Corp; and ViiV Healthcare.

Follow along with an expanded slideset at:
https://bit.ly/3syWD5T

Link to full program:
https://bit.ly/3z8SBnC

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Optimizing Use of Oral HIV PrEP

support@deceraclinical.com (Darrell H S Tan MD FRCPC PhD) — Thu, 12 Aug 2021 20:30:00 +0000

During this episode, Darrell H. S. Tan, MD, FRCPC, PhD, discusses approved and guideline-recommended oral HIV PrEP regimens and provides key insights on determining PrEP candidacy as well as important considerations for specific populations/clinical scenarios, including adolescents, pregnancy/breastfeeding, and transgender individuals.

Presenter:

Content based on an online CME program supported by an independent educational grant from Gilead Sciences, Inc.

Link to full program:
https://bit.ly/3AFvsZY

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The HBV Gray Zone: Patient and Physician Sharing Session #5

support@deceraclinical.com (Anna Christina L. dela Cruz MD) — Wed, 28 Jul 2021 20:30:00 +0000

In episode 5 of an ongoing series of sharing sessions between a physician and patient, Anna Christina L. dela Cruz, MD, and Rhonda, who is living with chronic hepatitis B, discuss what to do when the decision to start treatment is not clear because of borderline ALT test results and HBV DNA levels. Their conversation highlights a need for patient education and shared decision-making.

Presenter:

Anna Christina L. dela Cruz, MD
Associate Professor
Division of Digestive Diseases and Nutrition
Department of Internal Medicine
University of Kentucky
Lexington, Kentucky

Content based on an online CME program supported by an independent educational grant from Gilead Sciences.

Link to full program:
https://bit.ly/3u196yK

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Hepatitis B Reactivation: Patient and Physician Sharing Session #4

Mon, 26 Jul 2021 20:30:00 +0000

In episode 4 of an ongoing series of sharing sessions between a physician and patient, Geoffrey M. Dusheiko, MD, FCP(SA), FRCP, discusses hepatitis B diagnosis and treatment with his patient, Mark. The conversation focuses on Mark’s missed HBV diagnosis and likely reactivation following treatment for rheumatoid arthritis and raises awareness for needed improvements to communication between multidisciplinary healthcare teams.

Presenter:

Geoffrey M. Dusheiko MD, FCP(SA), FRCP
Emeritus Professor of Medicine
University College London School of Medicine
Kings College Hospital
London, United Kingdom

Content based on an online CME program supported by an independent educational grant from Gilead Sciences.

Link to full program:
https://bit.ly/3u196yK

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Tackling Racial Disparities in HCV Care

Thu, 22 Jul 2021 22:00:00 +0000

In this episode, Oluwaseun Falade-Nwulia, MBBS, MPH, and Joseph K. Lim, MD, examine the HCV burden and care disparities in specific populations, including Black, Hispanic, Asian, American Indian, and Alaska Native persons, and strategies to address barriers to care.

Joseph K. Lim, MD
Professor of Medicine
Director, Clinical Hepatology
Vice-Chief
Section of Digestive Diseases
Yale University School of Medicine
New Haven, Connecticut

Content based on a CME program supported by educational grants provided by AbbVie, Gilead Sciences, Inc., and Janssen Therapeutics, Division of Janssen Products, LP

To follow along, download the slides at:
https://bit.ly/36UDLVi

Link to full program:
https://bit.ly/3kKIb9a

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Virtual EASL 2021: Rapid Audio Recap

support@deceraclinical.com (Stefan Zeuzem MD) — Mon, 19 Jul 2021 21:15:00 +0000

In this episode, Stefan Zeuzem, MD, discusses exciting new data on viral hepatitis reported at the virtual EASL 2021, including new findings on treatment of HDV, treatment of HBV and HCV in children, linking patients to care, and new molecules being investigated for HBV cure.

Stefan Zeuzem, MD
Professor of Medicine
Chief, Department of Medicine I
JW Goethe University Hospital
Frankfurt, Germany

Content based on a CME program supported by educational grants provided by AbbVie, Antios Therapeutics, and Gilead Sciences, Inc.

To follow along, download the slides at:
https://bit.ly/3rl8AeS

Link to full program:
https://bit.ly/3ky46QK

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An HIV Vaccine: An Unfulfilled Promise—Episode 4, Looking Toward a Fulfilled Promise

support@deceraclinical.com (Decera Clinical Education) — Fri, 16 Jul 2021 20:30:00 +0000

Produced in collaboration with the Global HIV Vaccine Enterprise at the International AIDS Society (IAS), this 4-episode podcast series features conversations between world-renowned guests in HIV vaccine development, HIV advocacy, and HIV policy to bust myths and address arguments for why an HIV vaccine is still needed and how we can continue working toward this ultimate game-changer for durable control of the HIV epidemic. In this episode,Drs Elizabeth Bukusi, Peter Godfrey-Faussett, and Nina Russell discuss promising advances in the field of HIV vaccine research and how we can prepare for optimal rollout of an eventual HIV vaccine.

Presenters:

Elizabeth Anne Bukusi, MBChB, M.Med (ObGyn), MPH, PhD , PGD (Research Ethics), MBE (Research Ethics), CIP
Senior Principal Clinical Research Scientist
Center for Microbiology Research
KEMRI
Research Professor
Departments of Global Health and Obstetrics and Gynecology
University of Washington,
Nairobi, Kenya
Seattle, Washington

Peter Godfrey-Faussett, MBBS, FRCP(UK)
Science Advisor
United Nations Joint Programme on HIV (UNAIDS)
Professor of Infectious Diseases and International Health
London School of Hygiene and Tropical Medicine
London, United Kingdom

Nina Russell, MD
Director for TB and HIV Prevention
Bill & Melinda Gates Foundation
Seattle, Washington

Link to full series:
https://bit.ly/2UgrQ12

Link to the HIV unmuted series from IAS: https://hivunmuted.iasociety.org/

Content is part of a CME-certified educational program that is supported by independent educational grants from Gilead Sciences, Inc.; Janssen Therapeutics, Division of Janssen Products, LP; Merck Sharp & Dohme Corp; and ViiV Healthcare.

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Respiratory Syncytial Virus in Older Adults: Understanding Risk, Diagnosis, and Evolving Prevention Strategies

Thu, 15 Jul 2021 20:55:00 +0000

In this podcast, Spencer H. Durham, PharmD, BCPS, BCIDP; Stefan Gravenstein, MD, MPH; and Barbara Resnick, PhD, CRNP, discuss risk factors for respiratory syncytial virus among adults, the need for a vaccination strategy in this population, and the evolving clinical studies on vaccines for older adults. Following their dialogue, the faculty field questions from healthcare professionals.

Presenters:

Spencer H. Durham, PharmD, BCPS, BCIDP
Associate Clinical Professor of Pharmacy Practice
Director, Alumni & Professional Affairs Clinical Affairs & Outreach
Auburn University Harrison School of Pharmacy
Auburn, Alabama

Stefan Gravenstein, MD, MPH
Director
Division of Geriatrics and Palliative Medicine
The Warren Alpert Medical School of Brown University
Providence, Rhode Island

Barbara Resnick, PhD, CRNP
Professor
School of Nursing
University of Maryland
Nurse Practitioner
Roland Park Place
Baltimore, Maryland

Content based on an online CME program supported by educational grants from Janssen Therapeutics, Division of Janssen Products, LP.

Link to full program:
https://bit.ly/3kvr8ro

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An HIV Vaccine: An Unfulfilled Promise—Episode 3, Increasing Global Advocacy and Funding

Tue, 13 Jul 2021 20:35:00 +0000

Produced in collaboration with the Global HIV Vaccine Enterprise at the International AIDS Society (IAS), this 4-episode podcast series features conversations between world-renowned guests in HIV vaccine development, HIV advocacy, and HIV policy to bust myths and address arguments for why an HIV vaccine is still needed and how we can continue working toward this ultimate game-changer for durable control of the HIV epidemic. In this episode, Dr. Swati Gupta and Mr. Marc Dixneuf discuss how to broaden global advocacy and increase investment for an HIV vaccine.

Presenters:

Swati Gupta, DrPH, MPH
Vice President and Head of Emerging Infectious Diseases and Scientific Strategy
International AIDS Vaccine Initiative
New York, New York

Marc Dixneuf, PhD
Director General
AIDES
Pantin, France

Special Commentator:

Jonathan Weber, MB, BChir, PhD, FRCP, FRCPath, FMed Sci
Dean of the Faculty of Medicine
Imperial College
London, United Kingdom

Link to full series:
https://bit.ly/3ytytMY

Link to the HIV unmuted series from IAS:
https://bit.ly/3f5qC0d

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HIV-ASSIST: A Free, Online Tool for Individualized, Evidence-Based ART Selection—Audio Recap 2

support@deceraclinical.com (Jehan Budak MD) — Thu, 8 Jul 2021 20:30:00 +0000

In this episode, Jehan Budak, MD, discusses the use of HIV-ASSIST, a free, online, decision-support tool to inform ART selection.

Jehan Budak, MD
Assistant Professor
Division of Allergy & Infectious Diseases
University of Washington
Seattle, Washington

Content based on a CME program supported by educational grants from Gilead Sciences, Inc.; Theratechnologies; and ViiV Healthcare.

Link to full program:
https://bit.ly/33RZ9Zy

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Key Decisions in HIV Care: Initiating PrEP

support@deceraclinical.com (Latesha Elopre MD MSPH) — Wed, 7 Jul 2021 21:00:00 +0000

In this episode, Latesha Elopre, MD, MSPH, explains how to initiate pre-exposure prophylaxis (PrEP), including in underserved communities, with examples on overcoming barriers and improving access.

Listen as she gives her perspectives on:

Evidence for PrEP efficacy in the DISCOVER study
Recommendations in MSM, heterosexual men and women, injection drug users, and adolescents and adults weighing more than 77 lb
CDC guidance
How PrEP is underused, including racial/ethnic disparities
Strategies to overcoming barriers

Presenter:

Latesha Elopre, MD, MSPH
Assistant Professor
Division of Infectious Diseases
Director of Diversity and Inclusion
General Medical Education
University of Alabama at Birmingham
Birmingham, Alabama

Follow along with the slides at:
https://bit.ly/3ABCNL8

See the entire program at:
https://bit.ly/2TXTYWx

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Key Decisions in HIV Care: Switching to Long-Acting ART

support@deceraclinical.com (Daniel J Kuritzkes MD) — Wed, 7 Jul 2021 20:55:00 +0000

In this episode, Daniel J. Kuritzkes, MD, reviews key clinical trial data and gives practical insights such as how to initiate a patient on long-acting therapy, recommended dosing regimens, and factors that may increase the risk of treatment failure. The overview will include analyses of:

ATLAS and FLAIR studies of long-acting injectable CAB + RPV
ATLAS 2M dosing study
FDA approval and DHHS statement on use of long-acting injectable ART
Studies on whether an oral lead-in is needed

Presenter:

Daniel R. Kuritzkes, MD
Chief, Division of Infectious Diseases
Brigham and Women’s Hospital
Harriet Ryan Albee Professor of Medicine
Harvard Medical School
Boston, Massachusetts

Follow along with the slides at:
https://bit.ly/3hNfHII

See the entire program at:
https://bit.ly/2TXTYWx

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Emerging Insights on Adverse Events During ART and Implications for Treatment

support@deceraclinical.com (Darcy Wooten MD, Joseph J. Eron Jr. MD) — Tue, 6 Jul 2021 20:35:00 +0000

In this episode, Joseph J. Eron, Jr., MD, and Darcy Wooten, MD, share insights on HIV antiretroviral therapy safety and tolerability including recent data on weight gain and metabolic implications with INSTIs and NRTIs as well as the latest updates and recommendations on dolutegravir and pregnancy.

Joseph J. Eron, Jr., MD
Professor of Medicine and Epidemiology
University of North Carolina School of Medicine
Director, AIDS Clinical Trials Unit
University of North Carolina
Chapel Hill, North Carolina

Darcy Wooten, MD
Associate Professor of Medicine
Division of Infectious Diseases and Global Public Health
Department of Medicine
University of California, San Diego
San Diego, California

Content based on a CME program supported by independent educational grants from Janssen Therapeutics, Division of Janssen Products, LP, and ViiV Healthcare

Link to full program:
https://bit.ly/3ydMtcL

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Contemporary Management of HIV 2021: Frontiers in HIV Prevention, Part 2—Audio Recap

support@deceraclinical.com (Joseph J Eron Jr MD) — Wed, 30 Jun 2021 20:30:00 +0000

Listen to expert insights from Joseph J. Eron, Jr., MD, on exciting data about investigational agents (dapivirine ring, islatravir, lenacapavir, broadly neutralizing antibodies) for next-generation HIV prevention.

Link to full program:
https://bit.ly/3ux6FF8

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An HIV Vaccine: An Unfulfilled Promise—Episode 2, Learning Through Failing

Fri, 18 Jun 2021 20:15:00 +0000

Produced in collaboration with the Global HIV Vaccine Enterprise at the International AIDS Society (IAS), this 4-episode podcast series features conversations between world-renowned guests in HIV vaccine development, HIV advocacy, and HIV policy to bust myths and address arguments for why an HIV vaccine is still needed and how we can continue working toward this ultimate game-changer for durable control of the HIV epidemic. In this episode, Dr. Susan Buchbinder and Mr. Jontraye Davis discuss what has been learned and built through the past 40 years of HIV vaccine research, including how HIV vaccine scientific advancements and infrastructure were critical to the success of developing a COVID-19 vaccine.

Presenters:

Susan Buchbinder, MD
Clinical Professor
Departments of Medicine, Epidemiology and Biostatistics
University of California, San Francisco
Director, Bridge HIV
San Francisco Department of Public Health
San Francisco, California

Jontraye Davis, MHA, PMD Pro
Community Program Manager
FHI 360
Adjunct Instructor
North Carolina Central University
Durham, North Carolina

Special Commentator:

Jerome H. Kim, MD
Director General
International Vaccine Institute
Seoul, South Korea

Link to full series:
https://bit.ly/3ytytMY

Link to the HIV unmuted series from IAS:
https://bit.ly/3f5qC0d

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Contemporary Management of HIV 2021: First-line ART and Weight Gain—Audio Recap

support@deceraclinical.com (David A. Wohl MD) — Tue, 15 Jun 2021 21:10:00 +0000

In this episode, David A. Wohl, MD, discusses current guidelines and clinical trial data informing optimal selection of first-line antiretroviral therapy for HIV.

David A. Wohl, MD
Professor of Medicine
School of Medicine
Site Leader, AIDS Clinical Trials Unit-Chapel Hill
University of North Carolina at Chapel Hill
Director, North Carolina AIDS Training and Education Center
Chapel Hill, North Carolina
Co-Director, HIV Services
North Carolina Department of Correction
Raleigh, North Carolina

Link to full program:
https://bit.ly/3ux6FF8

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Evolving Care of Heavily Treatment–Experienced Patients With HIV: Answering the Questions

Tue, 15 Jun 2021 20:40:00 +0000

In this episode, Roger Bedimo, MD, MS, FACP; Princy N. Kumar, MD, FIDSA, MACP; and Brian Wood, MD, answer healthcare professionals’ most pressing questions on caring for heavily treatment–experienced patients with HIV.

Faculty:

Princy N. Kumar, MD, FIDSA, MACP
Professor of Medicine and Microbiology
Chief, Division of Infectious Diseases and Tropical Medicine
Senior Associate Dean of Students
Georgetown University School of Medicine
Washington, DC

Brian Wood, MD
Associate Professor of Medicine
Division of Allergy and Infectious Diseases
University of Washington
Seattle, Washington

Content based on an online CME/CPE-certified program supported by educational grant from ViiV Healthcare.

Link to full program:
https://bit.ly/3g8aBHs

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Optimizing Switch Strategies for Patients With Viral Suppression

support@deceraclinical.com (Chloe Orkin MBChB FRCP MD, Daniel R Kuritzkes MD) — Thu, 10 Jun 2021 20:50:00 +0000

In this episode, the first in a yearlong series on Key Decisions in HIV Care, Daniel R. Kuritzkes, MD, and Chloe Orkin, MBChB, FRCP, MD, discuss important considerations when switching ART in patients with viral suppression on their current regimen, including guideline recommendations and data supporting different switch regimen options such as single-tablet triple therapy, 2-drug oral regimens, doravirine-based regimens, and long-acting injectable therapy. Following their dialogue, the faculty field questions from healthcare professionals.

Presenters:

Daniel R. Kuritzkes, MD
Chief, Division of Infectious
Diseases
Brigham and Women's Hospital
Harriet Ryan Albee Professor of Medicine
Harvard Medical School
Boston, Massachusetts

Content based on an online CME program supported by educational grants from Gilead Sciences, Inc.; Janssen Therapeutics, Division of Janssen Products, LP; and ViiV Healthcare.

Link to full program:
https://bit.ly/2TXTYWx

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Contemporary Management of HIV 2021: Frontiers in HIV Prevention—Audio Recap

support@deceraclinical.com (W David Hardy MD) — Wed, 2 Jun 2021 20:30:00 +0000

Listen to expert insights from W. David Hardy, MD, on current options for pre-exposure prophylaxis and exciting new data on next-generation HIV prevention.

W. David Hardy, MD
Scientific and Medical Consultant
Adjunct Clinical Professor of Medicine
Division of Infectious Diseases
Keck School of Medicine of USC
Los Angeles, California

Content based on a CME program supported by an independent educational grant from ViiV Healthcare.

Link to full program:
https://bit.ly/3ux6FF8

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An HIV Vaccine: An Unfulfilled Promise− Episode 1, The Ultimate Game Changer

Thu, 20 May 2021 20:30:00 +0000

Produced in collaboration with the Global HIV Vaccine Enterprise at the International AIDS Society (IAS), this 4-episode podcast series features conversations between world-renowned guests in HIV vaccine development, HIV advocacy, and HIV policy to bust myths and address arguments for why an HIV vaccine is still needed and how we can continue working toward this ultimate game-changer for durable control of the HIV epidemic. In this first episode, Dr. Linda-Gail Bekker and Ms. Maureen Luba discuss why an HIV vaccine remains the ultimate game-changer to ending the epidemic and the gaps it will address in the expanding HIV prevention landscape.

Presenters:

Linda-Gail Bekker, MBChB, DTM&H, DCH, FCP(SA), PhD
Chief Operating Officer
Desmond Tutu HIV Foundation
Deputy Director
Desmond Tutu HIV Centre
Past President
International AIDS Society
Faculty of Health Sciences
University of Cape Town
Cape Town, South Africa

Maureen Luba
Africa Region Advocacy Advisor
Global Advocacy for HIV Prevention
AIDS Vaccine Advocacy Coalition

Link to full series:
https://bit.ly/3ytytMY

Link to the HIV unmuted series from IAS:
https://bit.ly/3f5qC0d

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Contemporary Management of HIV 2021: New Data from CROI 2021—Audio Recap

support@deceraclinical.com (Michelle S. Cespedes MD MS, Daniel R. Kuritzkes MD) — Tue, 18 May 2021 21:00:00 +0000

In this episode, Daniel R. Kuritzkes, MD, and Michelle S. Cespedes, MD, MS, discuss new ART data from virtual CROI 2021.

Michelle S. Cespedes, MD, MS
Associate Professor of Medicine
Division of Infectious Disease
Department of Medicine
Icahn School of Medicine at Mount Sinai
Attending Physician
Mount Sinai Medical Center
New York, New York

Daniel R. Kuritzkes, MD
Chief, Division of Infectious Diseases
Brigham and Women’s Hospital
Professor of Medicine
Harvard Medical School
Boston, Massachusetts

Content based on a CME program supported by an independent educational grant from ViiV Healthcare.

Link to full program:
https://bit.ly/3ux6FF8

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

HIV-ASSIST: A Free, Online Tool for Individualized, Evidence-Based ART Selection—Audio Recap

support@deceraclinical.com (Ethel D. Weld MD PhD) — Tue, 18 May 2021 20:35:00 +0000

In this episode, Ethel D. Weld, MD, PhD, demonstrates the use of HIV-ASSIST, a free, online, decision support tool to inform ART selection.

Ethel D. Weld, MD, PhD
Assistant Professor of Medicine, Pharmacology, & Molecular Sciences
Division of Clinical Pharmacology
Department of Infectious Diseases
Johns Hopkins University School of Medicine
Attending Physician
Inpatient HIV Service
General Infectious Diseases Consult Services
Johns Hopkins Hospital
Baltimore, Maryland

Content based on a CME program supported by educational grants from Gilead Sciences, Inc.; Theratechnologies; and ViiV Healthcare.

Link to full program:
https://bit.ly/33RZ9Zy

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To Treat or Not to Treat: Patient and Physician Sharing Session #3

support@deceraclinical.com (Jordan J Feld MD) — Tue, 11 May 2021 20:20:00 +0000

In episode 3 of an ongoing series of sharing sessions between a physician and patient, Jordan J. Feld, MD, MPH, and Wendy, who is living with chronic hepatitis B, discuss the challenges of determining the best time to start treatment. The conversation focuses on incorporating shared decision-making, particularly for cases that are not straight forward and do not fit into an one specific category outlined by the guidelines.

Presenter:

Jordan J. Feld, MD, MPH
Associate Professor of Medicine
University of Toronto
Hepatologist
Toronto Centre for Liver Disease
Sandra Rotman Centre for Global Health
Toronto, Canada

Content based on an online CME program supported by an independent educational grant from Gilead Sciences.

Link to full program:
https://bit.ly/3u196yK

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Contemporary Management of HIV 2021: Initiating First-line ART—Audio Recap

support@deceraclinical.com (William R Short MD) — Fri, 7 May 2021 20:30:00 +0000

In this episode, William R. Short, MD, MPH, AAHIVS, discusses current guidelines and clinical trial data informing optimal selection of first-line antiretroviral therapy for HIV.

Content based on a CME program supported by an independent educational grant from ViiV Healthcare.

Link to full program:
https://bit.ly/3ux6FF8

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Managing HIV in Aging Patients: Answering the Questions, Part 4

support@deceraclinical.com (Cristina Mussini MD) — Mon, 3 May 2021 20:30:00 +0000

In Part 4 of this 4-part series, listen to Howard Grossman, MD, and Cristina Mussini, MD, answer healthcare professionals’ questions on vaccine recommendations, bone health and fragility fractures, and racial disparities and social determinants that affect caring for patients aging with HIV.

Presenters:

Howard Grossman, MD
Clinical Affiliate Assistant Professor
Department of Integrated Medical Science
Charles E. Schmidt College of Medicine
Florida Atlantic University
Boca Raton, Florida
Medical Director, West Palm Beach, Wilton Manors, and Key West
Midway Specialty Care
Wilton Manors, Florida

Cristina Mussini, MD
Head, Department of Infectious Diseases and Tropical Medicine
Full Professor of Infectious Disease
Infectious Disease Clinics, University Hospital
University of Modena and Reggio Emilia
Modena, Italy

Content based on an online CME/CE/CPE-certified program supported by educational grants from Gilead Sciences, Inc.; Merck Sharp & Dohme Corp.; and ViiV Healthcare.

Link to full program:
http://bit.ly/32JD145

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Cases and Controversies in HIV: ART Simplification

Tue, 27 Apr 2021 20:30:00 +0000

In this episode, Drs José R. Arribas, Andrew Carr, and Lynora Saxinger discuss simplification strategies for a virologically suppressed patient with HIV and a complex ART treatment history.

Presenters:

José R. Arribas, MD
Research Director, HIV and Infectious Diseases
Hospital La Paz IdiPAZ
Madrid, Spain

Andrew Carr, MBBS, MD, FRACP, FRCPA
Professor of Medicine
University of New South Wales
Director, HIV and Immunology Unit
St Vincent’s Hospital
Sydney, Australia

Lynora Saxinger, MD, FRCPC, CTropMed
Cochair, Scientific Advisory Group
Alberta COVID-19 Emergency
Coordination Centre
Associate Professor
Division of Infectious Diseases
Department of Medicine
University of Alberta
Edmonton, Alberta
Canada

Content based on an online CME program supported by an independent educational grant from Gilead Sciences, Inc.

Link to full program:
https://bit.ly/3xdgcTk

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Cases and Controversies in HIV: ART and Pregnancy

Mon, 26 Apr 2021 20:30:00 +0000

In this episode, Drs José R. Arribas, Andrew Carr, and Lynora Saxinger discuss ART safety and management in a woman who wishes to conceive.

Presenters:

José R. Arribas, MD
Research Director, HIV and Infectious Diseases
Hospital La Paz IdiPAZ
Madrid, Spain

Andrew Carr, MBBS, MD, FRACP, FRCPA
Professor of Medicine
University of New South Wales
Director, HIV and Immunology Unit
St Vincent’s Hospital
Sydney, Australia

Lynora Saxinger, MD, FRCPC, CTropMed
Cochair, Scientific Advisory Group
Alberta COVID-19 Emergency
Coordination Centre
Associate Professor
Division of Infectious Diseases
Department of Medicine
University of Alberta
Edmonton, Alberta
Canada

Content based on an online CME program supported by an independent educational grant from Gilead Sciences, Inc.

Link to full program:
https://bit.ly/3xdgcTk

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Cases and Controversies in HIV: ARV-Associated Weight Gain

Fri, 23 Apr 2021 20:30:00 +0000

In this episode, Drs José R. Arribas, Andrew Carr, and Lynora Saxinger discuss weight gain concerns for a patient with initiating ART.

Presenters:

José R. Arribas, MD
Research Director, HIV and Infectious Diseases
Hospital La Paz IdiPAZ
Madrid, Spain

Andrew Carr, MBBS, MD, FRACP, FRCPA
Professor of Medicine
University of New South Wales
Director, HIV and Immunology Unit
St Vincent’s Hospital
Sydney, Australia

Lynora Saxinger, MD, FRCPC, CTropMed
Cochair, Scientific Advisory Group
Alberta COVID-19 Emergency
Coordination Centre
Associate Professor
Division of Infectious Diseases
Department of Medicine
University of Alberta
Edmonton, Alberta
Canada

Content based on an online CME program supported by an independent educational grant from Gilead Sciences, Inc.

Link to full program:
https://bit.ly/3xdgcTk

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Stigma as a Barrier to HBV Care: Patient and Physician Sharing Session #2

support@deceraclinical.com (Robert Gish MD FAASLD) — Mon, 12 Apr 2021 20:20:00 +0000

In episode 2 of an ongoing series of sharing sessions between a physician and patient, Robert Gish, MD, FAASLD, and patient advocate, Alan Wang, discuss stigma as a barrier to optimal HBV care and treatment. The conversation focuses on how stigma affected Alan’s engagement with his care and strategies to overcome stigma as a barrier to HBV care.

Presenter:

Robert Gish, MD, FAASLD
Medical Director
Hepatitis B Foundation
Medical Director
Asian Pacific Health Foundation
San Diego, California

Content based on an online CME program supported by an independent educational grant from Gilead Sciences.

Link to full program:
https://bit.ly/3u196yK

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Starting HBV Treatment in Pregnancy: Patient and Physician Sharing Session #1

support@deceraclinical.com (Grace LH Wong MD) — Fri, 26 Mar 2021 21:00:00 +0000

In episode 1 of this ongoing series, listen to a conversation between Grace LH Wong, MD, and her patient, Ms. Chan, on the shared decision for Ms. Chan to start treatment for hepatitis B infection during her pregnancy.

Presenter:

Grace LH Wong, MD
Professor
Division of Gastroenterology and Hepatology
Department of Medicine and Therapeutics
The Chinese University of Hong Kong
Honorary Consultant
Division of Gastroenterology and Hepatology
Department of Medicine and Therapeutics
Prince of Wales Hospital
Hong Kong

Content based on an online CME program supported by an independent educational grant from Gilead Sciences.

Link to full program:
https://bit.ly/3u196yK

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Virtual CROI 2021 – Rapid Recap

support@deceraclinical.com (Decera Clinical Education) — Thu, 18 Mar 2021 20:30:00 +0000

In this episode, Chloe Orkin, MBChB, FRCP, MD, discusses exciting new HIV data reported at the virtual CROI 2021, including new findings on HIV PrEP, HIV and COVID-19, ART in pregnancy and the postpartum period, as well as on the comparative efficacy of various ARV regimens.

Presenter:

Chloe Orkin, MBChB, FRCP, MD
Professor of HIV
Queen Mary University of London
Consultant Physician
Lead for HIV Research
Barts Health NHS Trust
The Royal London Hospital
London, United Kingdom

Content based on a CME program supported by educational grants from Gilead Sciences, Inc.; Janssen Therapeutics, Division of Janssen Products, LP; Merck Sharp & Dohme Corp; and ViiV Healthcare.

Link to full program:
http://bit.ly/3eUPAj9

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COVID-19: Answering the Questions, Part 17

support@deceraclinical.com (Arthur Kim MD) — Tue, 9 Mar 2021 22:15:00 +0000

In episode 17 of this series, Arthur Kim, MD, provides a brief update on the latest COVID-19 treatment options and guidelines. After the update, Dr. Kim answers questions submitted by healthcare professionals on various aspects of COVID-19.

Presenter:

Content based on an online CME program supported by an independent educational grant from Gilead Sciences.

Link to full program:
https://bit.ly/3eDoJF0

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4th HIV Research for Prevention Conference (HIVR4P // Virtual)—Rapid Recap

support@deceraclinical.com (Linda-Gail Bekker MBChB DTM&H DCH FCP(SA) PhD) — Thu, 18 Feb 2021 21:25:00 +0000

In this episode, Dr. Bekker discusses results from key studies reported at the 4th HIV Research for Prevention Conference (HIVR4P // Virtual), including results from studies evaluating novel approaches to HIV prevention such as broadly neutralizing antibodies, long-acting injectable and oral ARVs, and implantable options. In addition, Dr. Bekker will discuss several studies evaluating different aspects of PrEP implementation and acceptance as well as considerations for multipurpose prevention strategies.

Presenter:

Content based on a CME program supported by independent educational grants from Gilead Sciences, Inc.; Janssen Therapeutics, Division of Janssen Products, LP; Merck Sharp & Dohme Corp; and ViiV Healthcare.

Link to full program:
http://bit.ly/3s41GtM

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The IAS COVID-19 Conference: Prevention – Rapid Recap

support@deceraclinical.com (Jens D. Lundgren MD DMSc) — Thu, 18 Feb 2021 00:20:00 +0000

In this episode, Dr. Jens Lundgren discusses results from key studies reported at the IAS COVID-19 Conference: Prevention, including new findings on potential SARS-CoV-2 suppressive therapies, strategies for vaccination and mass testing, and interventions to prevent transmission of COVID-19 while maintaining desired outcomes in HIV care.

Jens D. Lundgren, MD, DMSc
Professor
Rigshospitalet, University of Copenhagen
Copenhagen, Denmark
Director
Centre of Excellence for Health, Immunity and Infection (CHIP)
Rigshospitalet, University of Copenhagen
Copenhagen, Denmark

Content based on a CME program supported by an independent educational grant from Gilead Sciences, Inc.

Link to full program:
http://bit.ly/3avWfhs

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COVID-19: Answering the Questions, Part 16

support@deceraclinical.com (Sharon R. Lewin AO FRACP PhD FAHMS) — Fri, 12 Feb 2021 21:25:00 +0000

In this episode, Part 16 of an ongoing series, Sharon R. Lewin, AO, FRACP, PhD, FAHMS, provides a brief update on emerging COVID-19 variants and their potential impacts on vaccine efficacy. After the update, Professor Lewin answers questions submitted by healthcare professionals on various aspects of COVID-19.

Presenter:

Sharon R. Lewin, AO, FRACP, PhD, FAHMS
Director, The Peter Doherty Institute for Infection and Immunity
Melbourne Laureate Professor of Infectious Diseases
University of Melbourne
Consultant Infectious Diseases Physician
Alfred Hospital and Royal Melbourne Hospital
Melbourne, Australia

Content based on an online CME program supported by an independent educational grant from Gilead Sciences.

Link to full program:
https://bit.ly/3eDoJF0

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Managing HIV in Aging Patients: Answering the Questions, Part 3

support@deceraclinical.com (Monica Gandhi MD MPH, Rajesh T. Gandhi MD) — Wed, 10 Feb 2021 21:30:00 +0000

In this episode, Part 3 of a 4-part series, Dr. Monica Gandhi, Dr. Rajesh Gandhi, and Dr. Josep Llibre discuss key health challenges faced by aging patients with HIV and answer clinicians’ questions on HIV treatment considerations and on prevention, screening, and treatment of common age-related comorbidities.

Presenters:

Rajesh T. Gandhi, MD
Professor of Medicine
Department of Infectious Diseases
Harvard Medical School
Physician, Infectious Diseases
Massachusetts General Hospital
Boston, Massachusetts

Josep M. Llibre, MD, PhD
Senior Consultant Physician and Clinical Researcher
Department of Infectious Diseases
Lluita Contra La SIDA Foundation
University Hospital, Germans Trias i Pujol
Badalona
Barcelona, Spain

Content based on an online CME/CE/CPE-certified program supported by educational grants from Gilead Sciences, Inc., Merck Sharp & Dohme Corp., and ViiV Healthcare.

Link to full program:
http://bit.ly/32JD145

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COVID-19: Answering the Questions, Part 15

support@deceraclinical.com (Roger Paredes MD PhD) — Mon, 25 Jan 2021 21:15:00 +0000

In this episode, Part 15 of an ongoing series, Roger Paredes, MD, PhD, provides a brief update on emerging COVID-19 variants and their potential impacts on the pandemic. After the update, Dr. Paredes answers clinician questions on various aspects of COVID-19.

Presenter:

Roger Paredes, MD, PhD
Section Chief, Infectious Diseases Department
Germans Trias i Pujol University Hospital
Head of the Microbial Genomics Group
IrsiCaixa AIDS Research Institute
Badalona, Catalonia, Spain

Content based on an online CME program supported by an independent educational grant from Gilead Sciences.

Link to full program:
https://bit.ly/3eDoJF0

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COVID-19: Answering the Questions, Part 14

support@deceraclinical.com (Vikramjit Mukherjee MD) — Thu, 31 Dec 2020 19:05:00 +0000

In this episode, Part 14 of an ongoing series, Vikramjit Mukherjee, MD, provides a brief update on COVID-19 mortality trends, including the latest data on overall and in-hospital fatality rates. After the update, Dr. Mukherjee answers clinician questions on various aspects of COVID-19.

Presenter:

Vikramjit Mukherjee, MD
Assistant Professor of Medicine
Division of Pulmonary, Critical Care, and Sleep Medicine
New York University School of Medicine
Director, Medical Intensive Care Unit
Bellevue Hospital
New York, New York

Content based on an online CME program supported by an independent educational grant from Gilead Sciences.

Link to full program:
http://bit.ly/3eDoJF0

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Contemporary Management of HIV: Evolving Issues in First-line Combination Therapy

support@deceraclinical.com (Daniel R. Kuritzkes MD, Joseph J. Eron Jr. MD) — Tue, 29 Dec 2020 21:15:00 +0000

In this episode, Joseph J. Eron, Jr., MD; and Daniel R. Kuritzkes, MD; discuss evolving issues in first-line antiretroviral therapy, including 2-drug therapy, weight gain, and safety during conception and pregnancy.

Presenters:

Joseph J. Eron, Jr., MD
Professor of Medicine and Epidemiology
University of North Carolina
School of Medicine
Director, AIDS Clinical Trials Unit
University of North Carolina
Chapel Hill, North Carolina

Daniel R. Kuritzkes, MD
Chief, Division of Infectious Diseases
Brigham and Women’s Hospital
Harriet Ryan Albee Professor of Medicine
Harvard Medical School
Boston, Massachusetts

Content based on an online CME program supported by an independent educational grant from ViiV Healthcare.

Link to full program:
http://bit.ly/34fVILZ

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Ending the HIV Epidemic: Strategies for Preventing New Infections

support@deceraclinical.com (Kenneth Mayer MD, Judith Feinberg MD) — Thu, 24 Dec 2020 19:00:00 +0000

In this episode, the third in a 3-part series on Ending the HIV Epidemic, Judith Feinberg, MD, and Kenneth Mayer, MD, discuss the important role of HIV pre-expsoure prophylaxis (PrEP) for preventing HIV infection among at-risk individuals and critical strategies for effective PrEP implementation among principle populations, including men who have sex with men and transgender women, heterosexual cisgender women, and people who inject drugs. Following their dialogue, the faculty field clinician questions on HIV prevention.

Presenters:

Judith Feinberg, MD
Professor
Attending Physician
Departments of Medicine and Behavioral Medicine & Psychiatry
West Virginia University School of Medicine
Morgantown, West Virginia

Kenneth Mayer, MD
Infectious Disease Attending
Beth Israel Deaconess Medical Center
Professor of Medicine
Harvard Medical School
Medical Research Director
Fenway Community Health
Boston, Massachusetts

Content based on an online CME program supported by educational grants from Gilead Sciences and ViiV Healthcare and produced in collaboration with PCE and HealthHIV.

Link to full program:
http://bit.ly/3263Q1s

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Contemporary Management of HIV: Heavily Treatment–Experienced Patients

support@deceraclinical.com (Eric S. Daar MD, Roger Bedimo MD MS FACP) — Fri, 18 Dec 2020 00:00:00 +0000

In this episode, Roger Bedimo, MD, MS, FACP, and Eric S. Daar, MD, discuss caring for heavily treatment–experienced patients with HIV, including assessment of virologic failure and current treatment options for patients with multiclass drug resistance.

Presenters:

Roger Bedimo, MD, MS, FACP
Professor of Medicine
Division of Infectious Diseases
University of Texas Southwestern Medical Center
Section Chief
Division of Infectious Diseases
Department of Internal Medicine
VA North Texas Health Care System
Dallas, Texas

Eric S. Daar, MD
Chief
Division of HIV Medicine
Harbor-UCLA Medical Center
Professor of Medicine
David Geffen School of Medicine at UCLA
Los Angeles, California

Content based on an online CME program supported by an independent educational grant from ViiV Healthcare.

Link to full program:
http://bit.ly/34fVILZ

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Ending the HIV Epidemic: Strategies for Achieving Rapid and Durable Virologic Suppression

support@deceraclinical.com (Aadia I. Rana MD, Jason Halperin MD MPH) — Tue, 8 Dec 2020 23:45:00 +0000

In this episode, the second in a 3-part series on Ending the HIV Epidemic, Jason Halperin, MD, MPH, and Aadia I. Rana, MD, discuss treatment as prevention, the critical infrastructure needed to implement rapid ART, the importance of routinely assessing for barriers to care, and real-time monitoring strategies that improve patient adherence and engagement. Following their dialogue, the faculty field clinician questions on HIV treatment and retention in care.

Presenters:

Jason Halperin, MD, MPH
Assistant Professor of Medicine
Department of Infectious Diseases
Tulane University
Infectious Disease Physician
CrescentCare
New Orleans, Louisiana

Aadia I. Rana, MD
Associate Professor of Medicine
Division of Infectious Diseases
The University of Alabama at Birmingham
1917 Clinic
Birmingham, Alabama

Content based on an online CME program supported by educational grants from Gilead Sciences and ViiV Healthcare and produced in collaboration with PCE and HealthHIV.

Link to full program:
https://bit.ly/3263Q1s

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COVID-19: Answering the Questions, Part 13

support@deceraclinical.com (Jens D. Lundgren MD DMSc) — Tue, 8 Dec 2020 23:45:00 +0000

In this episode, Part 13 of an ongoing series, Jens D. Lundgren, MD, DMSc, provides a brief update monoclonal antibody treatments for COVID-19, including the FDA Emergency Use Authorization for bamlanivimab and discusses the recently released information on COVID-19 vaccine efficacy. After the update, Professor Lundgren answers clinician questions on various aspects of COVID-19.

Presenter:

Content based on an online CME program supported by an independent educational grant from Gilead Sciences.

Link to full program:
https://bit.ly/3eDoJF0

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Viral Hepatitis Data From AASLD 2020 – Rapid Recap

support@deceraclinical.com (Norah Terrault MD MPH) — Wed, 25 Nov 2020 18:00:00 +0000

In this episode, Dr. Terrault discusses results from key viral hepatitis studies reported at the American Association for the Study of LiverDiseases (AASLD) 2020 annual conference, The Liver Meeting Digital Experience, including new findings on HBV treatment and management, hepatocellular carcinoma risk, and emerging approaches to HCV care in underserved populations.

Presenter:

Norah Terrault, MD, MPH
Professor of Medicine
Chief of Gastrointestinal and Liver Diseases
University of Southern California
Los Angeles, California

Content based on a CME program supported by an independent educational grant from Gilead Sciences, Inc.

Link to full program:
https://bit.ly/37bBrce

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What’s New in HIV Treatment Safety and Tolerability: Data From 2020 Conferences

support@deceraclinical.com (Brian Wood MD) — Mon, 23 Nov 2020 23:00:00 +0000

In this episode, Brian Wood, MD, discusses HIV treatment safety and tolerability data from 2020 conferences and addresses how he manages ARV-associated weight gain his patients and how the latest data on ART safety during conception and pregnancy impact his treatment recommendations.

Presenters:

Brian Wood, MD
Associate Professor of Medicine
Division of Allergy and Infectious Diseases
University of Washington
Seattle, Washington

Content based on an online CME/CE/CPE-certified program supported by educational grants from Janssen Therapeutics, Division of Janssen Products, LP.

Link to full program:
https://bit.ly/38YZVrz

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Managing HIV in Aging Patients: Answering the Questions, Part 2

support@deceraclinical.com (Decera Clinical Education) — Thu, 19 Nov 2020 21:25:00 +0000

In this episode, Part 2 of an 4-part series, Dr. Jonathan Appelbaum, Dr. Howard Grossman, and Professor Jürgen Rockstroh discuss key health challenges faced by aging patients with HIV and answer clinicians’ questions on HIV treatment considerations and on prevention, screening, and treatment of common age-related comorbidities.

Presenters:

Jonathan Appelbaum MD, FACP, AAHIVS
Laurie L. Dozier Jr, MD, Education Director
Professor of Medicine
Chair, Department of Clinical Sciences
Florida State University College of Medicine
Tallahassee, Florida

Howard Grossman, MD
Clinical Affiliate Assistant Professor
Department of Integrated Medical Science
Charles E. Schmidt College of Medicine
Florida Atlantic University
Boca Raton, Florida
Medical Director, West Palm Beach, Wilton Manors, and Key West
Midway Specialty Care
Wilton Manors, Florida

Jürgen Rockstroh, MD
Professor of Medicine
University of Bonn
Bonn, Germany

Content based on an online CME/CE/CPE-certified program supported by educational grants from Gilead Sciences, Inc., Merck Sharp & Dohme Corp., and ViiV Healthcare.

Link to full program:
https://bit.ly/32JD145

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Contemporary Management of HIV: ART Strategies for Complex HIV Cases

support@deceraclinical.com (Jason Halperin MD MPH, Joseph J. Eron Jr. MD) — Tue, 17 Nov 2020 21:30:00 +0000

In this episode, Dr. Joseph Eron and Dr. Jason Halperin discuss caring for complex HIV cases, including patients with underlying resistance or comorbidities.

Presenters:

Jason Halperin, MD, MPH
Assistant Professor of Medicine
Department of Infectious Diseases
Tulane University
Infectious Disease Physician
CrescentCare
New Orleans, Louisiana

Content based on an online CME program supported by an independent educational grant from ViiV Healthcare.

Link to full program:
https://bit.ly/34fVILZ

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COVID-19: Answering the Questions, Part 12

support@deceraclinical.com (David Heymann BA MD DTM&H) — Mon, 9 Nov 2020 21:40:00 +0000

In this episode, Part 12 of an ongoing series, David Heymann, BA, MD, DTM&H, provides a brief update on strategies for moving forward and living safely within the continued COVID-19 pandemic. After the update, Professor Heymann answers clinician questions on various aspects of COVID-19.

Presenter:

David Heymann, BA, MD, DTM&H
Professor of Infectious Disease Epidemiology
London School of Hygiene & Tropical Medicine
London, England

Content based on an online CME program supported by an independent educational grant from Gilead Sciences.

Link to full program:
https://bit.ly/3eDoJF0

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Ending the HIV Epidemic: Strategies for Earlier Diagnosis, Linkage to Care, and Outbreak Response

Wed, 4 Nov 2020 21:25:00 +0000

In this episode, the first in a 3-part series on Ending the HIV Epidemic, Lisa K. Fitzpatrick, MD, MPH, MPA, and David Malebranche, MD, MPH, discuss strategies to expand early HIV testing, maximize patient engagement in HIV care, navigate emerging clusters of HIV infection, and combat HIV-related stigma. Following their dialogue, the faculty field clinician questions on HIV diagnosis and management.

Presenters:

Lisa K. Fitzpatrick, MD, MPH, MPA
Professorial Lecturer
Department of Epidemiology
George Washington University School of Public Health
Interim Medical Director
BlueRock Care
Washington, DC

David J. Malebranche, MD, MPH
Board-Certified Internal Medicine Physician
HIV Specialist

Content based on an online CME program supported by educational grants from Gilead Sciences and ViiV Healthcare and produced in collaboration with PCE and HealthHIV.

Link to full program:
https://bit.ly/3263Q1s

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COVID-19 Data From IDWeek 2020 – Rapid Recap

support@deceraclinical.com (Rajesh T. Gandhi MD) — Fri, 30 Oct 2020 20:30:00 +0000

In this episode, Dr. Gandhi discusses results from key studies reported at the virtual IDWeek 2020 conference, including new findings on transmission in different settings, symptom progression and clinical outcomes, detection of non-SARS-CoV-2 viruses during the pandemic, and treatment and prevention strategies.

Presenter:

Rajesh T. Gandhi, MD
Professor of Medicine
Department of Infectious Diseases
Harvard Medical School
Physician, Infectious Diseases
Massachusetts General Hospital
Boston, Massachusetts

Content based on a CME program supported by an independent educational grant from Gilead Sciences, Inc.

Link to full program:
https://bit.ly/35HxQS8

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COVID-19: Answering the Questions, Part 11

support@deceraclinical.com (Sharon R. Lewin AO FRACP PhD FAHMS) — Thu, 29 Oct 2020 22:00:00 +0000

In this episode, Part 11 of an ongoing series, Sharon R. Lewin AO, FRACP, PhD, FAHMS, provides a brief update on the role of interferons in COVID-19. After the update, Dr. Lewin answers clinician questions on various aspects of COVID-19.

Presenter:

Sharon R. Lewin AO, FRACP, PhD, FAHMS
Director,
The Peter Doherty Institute for Infection and Immunity
Melbourne Laureate Professor of Infectious Diseases
University of Melbourne
Consultant Infectious Diseases Physician
Alfred Hospital and Royal Melbourne Hospital

Content based on an online CME program supported by an independent educational grant from Gilead Sciences.

Link to full program:
https://bit.ly/3eDoJF0

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HIV Glasgow 2020 Virtual – Rapid Recap

support@deceraclinical.com (Renslow Sherer MD) — Thu, 22 Oct 2020 20:30:00 +0000

In this episode, Dr. Sherer discusses results from key studies reported at the 2020 International Congress on Drug Therapy in HIV Infection (HIV Glasgow 2020 Virtual), including studies on long-term 2-drug and 3-drug antiretroviral therapy, newer 3-drug regimens in patients with baseline NRTI resistance, investigational HIV treatment approaches, and important comoribidities in patients with HIV, including COVID-19.

Presenter:
Renslow Sherer, MD
Director, International HIV Training Center
Professor of Medicine
University of Chicago
Chicago, Illinois

Content based on a CME program supported by independent educational grants from Gilead Sciences, Inc., Janssen Therapeutics, Division of Janssen Products, LP, and ViiV Healthcare.

Link to full program:
https://bit.ly/35nGqph

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COVID-19: Answering the Questions, Part 10

support@deceraclinical.com (Wong Chen Seong MBBS MRCP(UK) FAMS) — Fri, 16 Oct 2020 20:25:00 +0000

In this episode, Part 10 of an ongoing series, Wong Chen Seong, MBBS, MRCP(UK), FAMS, provides a brief update on COVID-19 and HIV. After the update, Dr. Wong answers clinician questions on various aspects of COVID-19.

Presenter:
Wong Chen Seong, MBBS, MRCP(UK), FAMS
Head, NCID Clinical HIV Programme
Deputy Director, National HIV Programme
National Centre for Infectious Diseases
Consultant
Department of Infectious Diseases
Tan Tock Seng Hospital
Programme Director
NHG Infectious Diseases Residency Programme
Adjunct Assistant Professor
Yong Loo Lin School of Medicine
National University of Singapore
Singapore

Content based on an online CME program supported by an independent educational grant from Gilead Sciences.

Link to full program:
https://bit.ly/3eDoJF0

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Virtual ECCVID 2020 Conference – Rapid Recap

support@deceraclinical.com (Barbara Rath MD PhD HDR) — Fri, 16 Oct 2020 20:20:00 +0000

In this episode, Dr. Rath discusses results from key studies reported at the European Society of Clinical Microbiology and Infectious Diseases Conference on Corona Virus Disease (ECCVID), including studies on COVID-19 screening and diagnostics, vaccines, prevention strategies, social disparities, and therapeutics.

Presenter:
Barbara Rath, MD, PhD, HDR
Co-founder & Chair
The Vienna Vaccine Safety Initiative
Research Director
Université de Bourgogne Franche-Comté, France
Honorary Professor
Executive Board Member
ESGREV (Respiratory Virus Study Group for ESCMID)

Content based on CME program supported by an independent educational grant from Merck & Co., Inc.

Link to full program:
https://bit.ly/37e6Hcc

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COVID-19: Answering the Questions, Part 9

support@deceraclinical.com (Lynora Saxinger MD FRCPC CTropMed) — Fri, 9 Oct 2020 20:25:00 +0000

In this episode, Part 9 of an ongoing series, Lynora Saxinger, MD, FRCPC, CTropMed, provides a brief update on key concepts in COVID-19 immunity and the latest information on treatment strategies. After the update, Dr. Saxinger answers clinician questions on various aspects of COVID-19.

Presenter:
Lynora Saxinger, MD, FRCPC, CTropMed
Cochair, Scientific Advisory Group
Alberta COVID-19 Emergency Coordination Centre
Associate Professor
Department of Medicine
Division of Infectious Diseases
University of Alberta
Edmonton, Albert
Canada

Content based on an online CME program supported by an independent educational grant from Gilead Sciences.

Link to full program:
https://bit.ly/3eDoJF0

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COVID-19: Answering the Questions, Part 8

support@deceraclinical.com (Paul E. Sax MD) — Tue, 6 Oct 2020 20:20:00 +0000

In this episode, Part 8 of an ongoing series, Paul E. Sax, MD, provides a brief update on current treatment options for COVID-19. After the update, Dr. Sax answers clinician questions on various aspects of COVID-19.

Presenter:

Paul E. Sax, MD
Clinical Director
HIV Program and Division of Infectious Diseases
Brigham and Women's Hospital
Professor of Medicine
Harvard Medical School
Boston, Massachusetts

Content based on an online CME program supported by an independent educational grant from Gilead Sciences.

Link to full program:
https://bit.ly/3eDoJF0

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Contemporary Management of HIV: Selecting Among Current ART Regimens for Initial ART

support@deceraclinical.com (W. David Hardy MD) — Fri, 2 Oct 2020 20:30:00 +0000

In this episode, W. David Hardy, MD, discusses current guidelines and clinical trial data informing optimal selection of first-line antiretroviral therapy for HIV.

Presenter:

W. David Hardy, MD
Scientific and Medical Consultant
Adjunct Professor of Medicine
Division of Infectious Diseases
Johns Hopkins University School of Medicine
Baltimore, Maryland

Content based on an online CME program supported by an independent educational grant from ViiV Healthcare.

Link to full program:
https://bit.ly/34fVILZ

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COVID-19: Answering the Questions, Part 7

support@deceraclinical.com (Leo Yee-Sin MBBS MPH MRCP FRCP FAMS) — Fri, 25 Sep 2020 20:30:18 +0000

In this episode, Part 7 of an ongoing 12-part COVID-19 series, Leo Yee-Sin, MBBS, MPH, MRCP, FRCP, FAMS, provides a brief update on COVID-19 risk and prevention strategies among healthcare workers. After the update, Professor Leo answers clinician questions on various aspects of COVID-19.

Presenter:

Leo Yee-Sin, MBBS, MPH, MRCP, FRCP, FAMS

Professor
Lee Kong Chian School of Medicine
Saw Swee Hock School of Public Health
Nanyang Technological University
National University of Singapore
Senior Consultant
National Centre for Infectious Disease
Singapore

Content based on an online CME program supported by an independent educational grant from Gilead Sciences.

Link to full program:
https://bit.ly/3eDoJF0

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COVID-19: Answering the Questions, Part 6

support@deceraclinical.com (Jens D. Lundgren MD DMSc) — Wed, 23 Sep 2020 20:30:01 +0000

In this episode, Part 6 of an ongoing 12-part COVID-19 series, Jens D. Lundgren, MD, DMSc, provides a brief update on vaccine development and treatment strategies. After the update, Dr. Lundgren answers clinician questions on various aspects of COVID-19.

Note that this podcast was recorded on August 4, 2020. Some information may have changed since that time.

Presenter:

Jens D. Lundgren, MD, DMSc
Professor
Rigshospitalet, University of Copenhagen
Copenhagen, Denmark
Director
Centre of Excellence for Health, Immunity and Infection (CHIP)
Rigshospitalet, University of Copenhagen
Copenhagen, Denmark

Content based on an online CME program supported by an independent educational grant from Gilead Sciences.

Link to full program:
https://bit.ly/3eDoJF0

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Managing HIV in Aging Patients: Answering the Questions, Part 1

Thu, 17 Sep 2020 20:30:06 +0000

In this episode, Part 1 of an 4-part series, Dr. Joseph J. Eron, Jr., Professor Chloe Orkin, and Dr. Paul E. Sax, discuss key health challenges faced by aging patients with HIV and answer clinicians’ questions on HIV treatment considerations and on prevention, screening, and treatment of common age-related comorbidities.

Presenters:
Joseph J. Eron, Jr., MD
Professor of Medicine and Epidemiology
University of North Carolina
School of Medicine
Director, AIDS Clinical Trials Unit
University of North Carolina
Chapel Hill, North Carolina

Chloe Orkin, MBChB, FRCP, MD
Professor of HIV
Queen Mary, University of London
Consultant Physician
Lead for HIV Research
Barts Health NHS Trust
The Royal London Hospital
London, United Kingdom

Paul E. Sax, MD
Clinical Director
HIV Program and Division of Infectious Diseases
Brigham and Women’s Hospital
Professor of Medicine
Harvard Medical School
Boston, Massachusetts

Content based on an online CME/CE/CPE-certified program supported by educational grants from Gilead Sciences, Inc., Merck Sharp & Dohme Corp., and ViiV Healthcare.

Link to full program:
https://bit.ly/32JD145

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EASL 2020 Virtual Conference: Rapid Audio Recap

support@deceraclinical.com (Stefan Zeuzem MD) — Mon, 14 Sep 2020 20:15:05 +0000

In this episode, Dr. Stefan Zeuzem discusses results from key viral hepatitis studies reported at the 2020 Digital International Liver Congress, organized by the European Association for the Study of the Liver, including important findings from the following reports:

Update on global progress toward HCV elimination goals
SToP-C: HCV treatment-as-prevention in Australian prisons
SHARED cohort: correlates of treatment failure with GLE/PIB or SOF/VEL/VOX
Trio Health: retreating HCV with GLE/PIB or SOF/VEL/VOX after DAA failure
Stop-NUC: discontinuation of long-term nucleos(t)ide analogue therapy in patients with HBeAg-negative chronic HBV infection
High-dose bulevirtide for chronic HBV/HDV coinfection
Summary of select agents under early-phase investigation for HBV treatment

Presenter:

Stefan Zeuzem, MD
Professor of Medicine
Chief, Department of Medicine I
JW Goethe University Hospital
Frankfurt, Germany

Content based on a CME program supported by an independent educational grant from Gilead Sciences.

Link to full program:
https://bit.ly/33nkRUI

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COVID-19: Answering the Questions, Part 5

support@deceraclinical.com (David Heymann BA MD DTM&H) — Wed, 2 Sep 2020 21:15:04 +0000

In this episode, Part 5 of an ongoing 12-part COVID-19 series, David Heymann, BA, MD, DTM&H, provides a brief update on the epidemiology of SARS-CoV-2 and evidence-based interventions for reducing transmission,. After the update, Professor Heymann answers critical clinician questions on COVID-19 transmission and mitigation.

Presenter:

David Heymann, BA, MD, DTM&H
Professor, Infectious Disease Epidemiology,
London School of Hygiene & Tropical Medicine; and
Distinguished Fellow,
Centre on Universal Health at Chatham House, London
London, United Kingdom

Content based on an online CME program supported by an independent educational grant from Gilead Sciences.

Link to full program: https://bit.ly/3eDoJF0

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Virtual COVID-19 2020 Conference: Rapid Audio Recap

support@deceraclinical.com (Renslow Sherer MD) — Wed, 19 Aug 2020 21:15:32 +0000

In this episode, Dr. Sherer discusses results from key studies reported at the International AIDS Society’s 2020 Virtual COVID-19 Conference, including studies evaluating characteristics and predictors of COVID-19 mortality, factors associated with remdesivir clinical outcomes, the effect of hydroxychloroquine coadministration on remdesivir safety and efficacy, the effect of race/ethnicity on clinical outcomes with remdesivir, and sofosbuvir/daclatasvir plus lopinavir/ritonavir for the treatment of severe COVID-19.

Presenter:

Renslow Sherer, MD
Director, International HIV Training Center
Professor of Medicine
University of Chicago
Chicago, Illinois

Content based on a CME program supported by an independent educational grant from Gilead Sciences.

Link to full program: https://bit.ly/2Q7GDp2

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AIDS 2020: Virtual – Rapid Audio Recap

support@deceraclinical.com (Decera Clinical Education) — Fri, 14 Aug 2020 21:15:04 +0000

In this episode, Dr. Orkin discusses results from key studies reported at AIDS 2020: Virtual, with new data on the following hot topics: current ART in principal populations, including older patients and women who become pregnant; metabolic outcomes during ART; HIV and COVID-19; investigational ART strategies; and HIV prevention. The overview includes:

The ADVANCE trial comparing initial ART with DTG plus FTC/TAF, DTG plus FTC/TDF, or EFV/FTC/TDF
A pooled analysis of randomized trials evaluating a switch to BIC/FTC/TAF in patients 65 years of age or older with virologic suppression on their current ART
A Kaiser Permanente study of BMI changes over time following ART initiation
An analysis of the longitudinal prospective OPERA cohort that assessed weight change with switch from TDF to TAF
Metabolic changes with switch from 3- or 4-drug TAF-based ART to 2-drug DTG/3TC in the TANGO study
Updated findings from the Tsepamo birth surveillance study in Botswana evaluating the prevalence of neural tube defects by antiretroviral exposure during conception/pregnancy
A retrospective study of COVID-19 in people with HIV presenting at 5 New York City Emergency Departments from March 2 to April 15, 2020
An analysis of protocol-defined virologic failure in the P011 study comparing islatravir plus DOR vs DOR/3TC/TDF in treatment-naive adults
A study evaluating the lenacapavir pharmacokinetic profile
Results from the HPTN 083 trial investigating the efficacy and safety of long-acting injectable cabotegravir vs daily oral TDF/FTC for PrEP in MSM and TGW

Presenter:
Chloe Orkin, MBChB, FRCP, MD
Professor of HIV
Queen Mary, University of London
Consultant Physician
Lead for HIV Research
Barts Health NHS Trust
The Royal London Hospital
London, United Kingdom

Content based on a CME program supported by independent educational grants from Gilead Sciences, Merck Sharp & Dohme Corp., and ViiV Healthcare.

Link to full program: https://bit.ly/33YRz0t

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COVID-19: Answering the Questions, Part 4

support@deceraclinical.com (Vikramjit Mukherjee MD) — Thu, 23 Jul 2020 21:30:19 +0000

In this episode, Part 4 of an ongoing 12-part COVID-19 series, Vikramjit Mukherjee, MD, provides a brief update on the latest incidence trends and a concise summary of updates to the US National Institutes of Health and the Infectious Diseases Society of America recommendations for managing COVID-19. After the update, Dr. Mukherjee answers critical clinician questions on COVID-19 transmission, diagnosis, and management.

Presenter:
Vikramjit Mukherjee, MD
Director, Medical Intensive Care Unit
Bellevue Hospital
Assistant Professor
Division of Pulmonary, Critical Care, and Sleep Medicine
NYU School of Medicine
New York, New York

Content based on an online CME program supported by an independent educational grant from Gilead Sciences.

Link to full program:
https://bit.ly/3eDoJF0

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Benefits of and Need for Integrated Addiction and Infectious Disease Care

support@deceraclinical.com (Christian B. Ramers MD MPH, Sandra Springer MD) — Thu, 9 Jul 2020 20:45:05 +0000

In this episode, Christian B. Ramers, MD, MPH, and Sandra Springer, MD, discuss current evidence supporting the need for integrated addiction and infectious disease care and review the wide array of benefits that can be realized when these services are provided in tandem, ideally at the same clinic and by the same healthcare provider.

Presenters:
Christian B. Ramers, MD, MPH
Associate Clinical Professor
Division of Infectious Diseases
Department of Medicine
UC San Diego School of Medicine
La Jolla, California
Chief, Population Health
Director, Graduate Medical Education
Family Health Centers of San Diego
San Diego, California

Sandra Springer, MD
Associate Professor of Medicine
Division of Infectious Disease
Department of Internal Medicine
Yale School of Medicine
New Haven, Connecticut
Attending Physician
Section of Infectious Disease
Department of Internal Medicine
Veterans Administration Connecticut Healthcare Services
West Haven, Connecticut

Content based on an online CME program supported by an independent educational grant from Gilead Sciences.

Link to full program:
https://bit.ly/2Zcdoqw

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COVID-19: Answering the Questions, Part 3

support@deceraclinical.com (Sharon Lewin AO FRACP PhD FAAHMS) — Mon, 29 Jun 2020 20:30:06 +0000

In this episode, Part 3 of an ongoing 12-part COVID-19 series, Sharon Lewin, AO, FRACP, PhD, FAAHMS, provides a brief update on the latest incidence trends and a concise guide to the management of mild and moderate disease. After the update, Dr. Lewin answers critical clinician questions on COVID-19 transmission, diagnosis, and management.

Presenter:
Sharon Lewin, AO, FRACP, PhD, FAAHMS
Director
The Peter Doherty Institute for Infection and Immunity
Professor of Infectious Diseases
University of Melbourne
Consultant Infectious Disease Physician
Alfred Hospital and Royal Melbourne Hospital
Melbourne, Australia

Content based on an online CME program supported by an independent educational grant from Gilead Sciences.

Link to full program:

https://bit.ly/3eDoJF0

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COVID-19: Answering the Questions, Part 2

support@deceraclinical.com (Jens D. Lundgren MD DMSc) — Fri, 12 Jun 2020 20:30:03 +0000

In this episode, Part 2 of an ongoing 12-part COVID-19 series, Jens D. Lundgren, MD, DMSc, provides a brief update on the latest incidence trends, a concise guide to viral diagnostic testing, and new data on investigational treatment options. After the update, Dr. Lundgren answers critical clinician questions on COVID-19 transmission, diagnosis, and management.

Presenter:
Jens D. Lundgren, MD, DMSc
Professor
Director, Centre of Excellence for Health, Immunity and Infection (CHIP)
Rigshospital
University of Copenhagen
Copenhagen, Denmark

Content based on an online CME program supported by an independent educational grant from Gilead Sciences.

Link to full program:

https://bit.ly/3eDoJF0

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Addressing Age-Related Comorbidities Among People With HIV

support@deceraclinical.com (Daniel R. Kuritzkes MD, Christian B. Ramers MD MPH) — Fri, 5 Jun 2020 19:15:06 +0000

In this episode, Dr. Kuritzkes and Dr. Ramers provide a case-based discussion addressing several age-related comorbidities among people with HIV, including bone loss, renal impairment, cardiovascular disease, mental health disorders, and neurocognitive disorders. Their discussion includes analysis of key data from the following HIV studies:

DRIVE-AHEAD: Neuropsychiatric Events With First-line DOR/3TC/TDF vs EFV/FTC/TDF
TANGO: Renal and Bone Changes With Switch to DTG/3TC
SWORD-1/2: Renal and Bone Changes With Switch to DTG + RPV
Study 1961: Quantitative Proteinuria by Baseline Regimen With Switch to BIC/FTC/TAF in Women
Studies 1216 and 1160: Bone Changes With Switch to RPV/FTC/TAF
NA-ACCORD: Increased MI Risk Among PWH
D:A:D: Increased CVD Risk With Boosted PIs
Danish HIV Cohort Study: Impact of Smoking on MI Risk
D:A:D: Impact of Smoking on MI Risk

In addition, Dr. Kuritzkes and Dr. Ramers discuss relevant data and practical strategies for smoking cessation among people with HIV as well as risk factors, pathogenesis, and challenges in the clinical management of HIV-associated neurocognitive disorders.

Presenters:

Daniel R. Kuritzkes, MD
Chief, Division of Infectious Diseases
Brigham and Women’s Hospital
Harriet Ryan Albee Professor of Medicine
Harvard Medical School
Boston, Massachusetts

Christian B. Ramers, MD, MPH
Associate Clinical Professor
Division of Infectious Diseases
Department of Medicine
UC San Diego School of Medicine
La Jolla, California
Chief, Population Health
Director, Graduate Medical Education
Family Health Centers of San Diego
San Diego, California

Content based on an online CME program supported by an independent educational grant from ViiV Healthcare.

Link to downloadable slideset associated with this podcast: https://bit.ly/2MuoEHF

Link to full program:
https://bit.ly/3cFzy8o

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COVID-19: Answering the Questions, Part 1

support@deceraclinical.com (Vikramjit Mukherjee MD) — Fri, 5 Jun 2020 19:15:06 +0000

In this episode, Part 1 of an ongoing 12-part COVID-19 series, Vikramjit Mukherjee, MD, provides a brief update on the latest incidence trends, the role of serology in disease assessment, and newly published data from the ACTT-1 trial comparing remdesivir vs placebo for severe COVID-19 treatment. After the update, Dr. Mukherjee answers critical clinician questions on COVID-19 transmission, diagnosis, and management.

Content based on an online CME program supported by an independent educational grant from Gilead Sciences.

Link to full program:

https://bit.ly/3eDoJF0

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Weight Gain During HIV Treatment and the Latest in HIV Prevention

support@deceraclinical.com (Monica Gandhi MD MPH) — Fri, 5 Jun 2020 19:15:06 +0000

In this episode, Dr. Gandhi discusses topline results from several studies investigating weight gain and metabolic outcomes with different antiretroviral therapy (ART) regimens among patients with HIV, including lipid level changes, cardiovascular disease risk, diabetes risk, and metabolic syndrome risk. The overview will include analyses from:

The ADVANCE trial comparing initial ART with DTG plus FTC/TAF, DTG plus FTC/TDF, or EFV/FTC/TDF, including an examination of the influence of CYP2B6 polymorphisms on weight change during EFV-based therapy
The NA-ACCORD study
- Evaluating patients with virologic suppression who switched from non–integrase inhibitor (INSTI)–based regimens to INSTI-based regimens
- Investigating the impact of initial ART regimen class on diabetes mellitus incidence
A study investigating the association between resting metabolic rate, oxygen consumption, and dietary intake changes and body weight/composition changes following ART initiation
A study evaluating differences in postpartum weight change with DTG-based vs EFV-based ART

In addition, Dr. Gandhi reviews new information on biomedical prevention of HIV infection, including results from several preclinical trials, a study investigating real-time urine-based testing for tenofovir levels, and the latest safety data from the phase III DISCOVER trial comparing FTC/TDF vs FTC/TAF for daily oral HIV pre-exposure prophylaxis (PrEP) among cis-gender men who have sex with men (MSM) and transgender women.

Presenter:
Monica Gandhi, MD, MPH
Professor of Medicine
Division of HIV, Infectious Diseases, and Global Medicine
University of California, San Francisco
Medical Director
Ward 86 HIV Clinic
San Francisco General Hospital
San Francisco, California

Content based on an online CME program supported by independent educational grants from Gilead Sciences; Merck & Co., Inc.; and ViiV Healthcare.

Link to full program:

https://bit.ly/3bBjeoD

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