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    <title>Transforming Health Insights</title>
    <description>Transforming Health Insights envisions a world where health innovation is accessible, understandable, and actionable for everyone. 

This podcast series from UBC Medicine, Office of Research, aims to bridge cutting-edge research, transformative biomedical discoveries, and real-world health outcomes, creating
conversations that inspire, inform, and empower listeners across disciplines.

This mini-series showcases researchers, trainees, clinicians, private and public sector partners across projects and units, strengthening and understanding the translational medicine process, sharing stories from B.C.’s flourishing life sciences sector as it reshapes healthcare in our province and beyond.

(C) 2026 UBC Medicine Learning Network</description>
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    <pubDate>Tue, 13 Oct 2026 07:00:00 +0000</pubDate>
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    <itunes:summary>Transforming Health Insights envisions a world where health innovation is accessible, understandable, and actionable for everyone. 

This podcast series from UBC Medicine, Office of Research, aims to bridge cutting-edge research, transformative biomedical discoveries, and real-world health outcomes, creating
conversations that inspire, inform, and empower listeners across disciplines.

This mini-series showcases researchers, trainees, clinicians, private and public sector partners across projects and units, strengthening and understanding the translational medicine process, sharing stories from B.C.’s flourishing life sciences sector as it reshapes healthcare in our province and beyond.

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      <title>Improving Care and Medical Education in the Age of AI</title>
      <description><![CDATA[<p>In this episode of <i>Transforming Health Insights</i>, we will learn from Dr. Raymond Ng and Dr. Anita Palepu about AI-driven decision support that is working on streamlining triaging for breast cancer patients in BC, with the goal of identifying high-risk patients earlier so they can access care. AI is advancing rapidly in healthcare, raising important questions about ethics and responsible use. We will explore how AI can be used to address complex health system challenges when deployed responsibly, while keeping humans at the center of decision making. UBC researchers are working to harness the power of AI in health care while building safeguards around privacy and ensuring that humans, not AI, make crucial health decisions and use AI for good.&nbsp;AI has the potential to reimagine health care if used responsibly and thoughtfully.&nbsp; &nbsp;<br>HOST: Chantal Moore, Scientific Communications and Engagement Strategist, UBC Office of Research</p><p>GUESTS: Dr. Anna Blakney, Assistant Professor, Michael Smith Laboratories and School of Biomedical Engineering at UBC and Dr. Pieter Cullis, Professor, Biochemistry and Molecular Biology, UBC Faculty of Medicine</p><p>Produced by<br>EdTech: Digital Solutions for Education and Office of Research, UBC Faculty of Medicine</p><p>Story Editors and Associate Producers<br>Neha Manjari Akella, Research Network Manager, MS Research Network, UBC Faculty of Medicine<br>Chantal Moore, Scientific Communications and Engagement Strategist, Office of Research, UBC Faculty of Medicine</p><p>Technical Production by<br>EdTech: Digital Solutions for Education, UBC Faculty of Medicine</p><p>Sound Recordist<br>Sam McGuinness, EdTech: Digital Solutions for Education, UBC Faculty of Medicine</p><p>Sound Editors<br>Sam McGuinness and Vanessa Reuter, EdTech: Digital Solutions for Education, UBC Faculty of Medicine</p><p>Associate Director, Research Programs &amp; Administration<br>Shelly Au, Office of Research, UBC Faculty of Medicine</p><p>Executive Director<br>Dr. Michelle Wong, Canada’s Immuno-engineering and Biomanufacturing Hub and Office of Research, UBC Faculty of Medicine</p><p>Senior Producer, Creative and Distribution<br>Stephen Gillis, EdTech: Digital Solutions for Education, UBC Faculty of Medicine</p><p>Executive Producer<br>Zachary Rothman, EdTech: Digital Solutions for Education, UBC Faculty of Medicine</p><p>Subscribe to the show and other UBC Medicine Learning Network podcasts on Apple, Spotify, YouTube, or your favourite podcast platform.<br>&nbsp;</p><p>Episode Chapters</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>[00:00]</strong> – Introduction and episode overview</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>[01:36]</strong> – Personal pathways into AI and Health</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>[03:57]</strong> – Expediting breast cancer triaging</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>[08:02]</strong> – Scaling AI models across health settings</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>[09:28] </strong>– AI’s role in clinical care</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>[11:06] </strong>– Equity, access and marginalized populations</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>[12:38] </strong>– Education and training around AI best practices</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>[15:44] </strong>– Responsible use and UBC AI and Health Network</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>[22:29] </strong>– Sustainability and environmental responsibility</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>[25:50]</strong> – Improve patient experience and healthcare impact</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>[28:16]</strong> – Future vision</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>[31:03]</strong> – Closing remarks</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>[31:31]</strong> – Knowledge nugget<br><br><strong>Resources &amp; References</strong></p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Learn more about</p><p>o&nbsp;&nbsp; AI and Health Network: <a href="https://aihealth.med.ubc.ca/" rel="noopener noreferrer">https://aihealth.med.ubc.ca/</a></p><p>o&nbsp;&nbsp; Dr. Raymond Ng: <a href="https://www.cs.ubc.ca/~rng/" rel="noopener noreferrer">https://www.cs.ubc.ca/~rng/</a></p><p>o&nbsp;&nbsp; Dr. Anita Palepu: <a href="https://datascienceandhealth.ubc.ca/people/anita-palepu" rel="noopener noreferrer">https://datascienceandhealth.ubc.ca/people/anita-palepu</a></p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Ng, Raymond. <i>New data centres need to be built for the right reasons</i> (September 21, 2026).<a href="https://www.theglobeandmail.com/gift/6f8ae90c134057a9373d4be8ee82374724bed37d8e992ba94cb5f4fc67883df2/XGRAG74R35CNFK7CW7TDCZQ7RI/" rel="noopener noreferrer">https://www.theglobeandmail.com/gift/6f8ae90c134057a9373d4be8ee82374724bed37d8e992ba94cb5f4fc67883df2/XGRAG74R35CNFK7CW7TDCZQ7RI/</a>.</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Gondara, Lovedeep, et al. "<a href="https://www.mdpi.com/2504-4990/7/4/121" rel="noopener noreferrer">Small or large? zero-shot or finetuned? guiding language model choice for specialized applications in healthcare</a>." Machine Learning and Knowledge Extraction 7.4 (2025): 121.</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Al-Najafi, Dheyaa, et al. "<a href="https://link.springer.com/article/10.1186/s12909-026-09671-0" rel="noopener noreferrer">Psychometric performance and student perceptions of AI-versus student-generated multiple-choice questions: a single-center randomized controlled trial</a>." BMC Medical Education 26.1 (2026): 1376.<br><br>&nbsp;</p>
<p><p>The Vancouver Fraser Medical Program and the Vancouver Academic Campus of the University of British Columbia are situated on the traditional territory of the Musqueam, Squamish and Tsleil-Waututh peoples. <br /><br />
  The Southern Medical Program and the Okanagan Academic Campus of the University of British Columbia are situated on the territory of the Syilx Okanagan Nation. <br /><br />
  The Northern Medical Program and the University of Northern BC are situated on the traditional territory of the Lheidli T’enneh, part of the Dakelh (Carrier) First Nations. <br /><br />
  With respect to the Lekwungen peoples on whose traditional territory the Island Medical Program and the University of Victoria stand, and the Songhees, Esquimalt and WSÁNEĆ peoples whose historical relationships with the land continue to this day. <br /><br />
 We acknowledge our traditional hosts and honour their welcome and graciousness to the students who seek knowledge here. <br /><br />
  All rights reserved. Reproduction and distribution of this presentation without written permission from UBC Faculty of Medicine is strictly prohibited.</p>
<p><br />
 © UBC Medicine Learning Network 2026 </p>
<p> </p></p><br/> <p>Hosted by Simplecast, an AdsWizz company. See <a href="https://pcm.adswizz.com">pcm.adswizz.com</a> for information about our collection and use of personal data for advertising.</p>]]></description>
      <pubDate>Tue, 13 Oct 2026 07:00:00 +0000</pubDate>
      <author>stephen.gillis@ubc.ca (Chantal Moore, Dr. Anita Palepu, Dr. Raymond Ng)</author>
      <link>https://transforming-health-insights.simplecast.com/episodes/improving-care-and-medical-education-in-the-age-of-ai-lm3KfbVS</link>
      <content:encoded><![CDATA[<p>In this episode of <i>Transforming Health Insights</i>, we will learn from Dr. Raymond Ng and Dr. Anita Palepu about AI-driven decision support that is working on streamlining triaging for breast cancer patients in BC, with the goal of identifying high-risk patients earlier so they can access care. AI is advancing rapidly in healthcare, raising important questions about ethics and responsible use. We will explore how AI can be used to address complex health system challenges when deployed responsibly, while keeping humans at the center of decision making. UBC researchers are working to harness the power of AI in health care while building safeguards around privacy and ensuring that humans, not AI, make crucial health decisions and use AI for good.&nbsp;AI has the potential to reimagine health care if used responsibly and thoughtfully.&nbsp; &nbsp;<br>HOST: Chantal Moore, Scientific Communications and Engagement Strategist, UBC Office of Research</p><p>GUESTS: Dr. Anna Blakney, Assistant Professor, Michael Smith Laboratories and School of Biomedical Engineering at UBC and Dr. Pieter Cullis, Professor, Biochemistry and Molecular Biology, UBC Faculty of Medicine</p><p>Produced by<br>EdTech: Digital Solutions for Education and Office of Research, UBC Faculty of Medicine</p><p>Story Editors and Associate Producers<br>Neha Manjari Akella, Research Network Manager, MS Research Network, UBC Faculty of Medicine<br>Chantal Moore, Scientific Communications and Engagement Strategist, Office of Research, UBC Faculty of Medicine</p><p>Technical Production by<br>EdTech: Digital Solutions for Education, UBC Faculty of Medicine</p><p>Sound Recordist<br>Sam McGuinness, EdTech: Digital Solutions for Education, UBC Faculty of Medicine</p><p>Sound Editors<br>Sam McGuinness and Vanessa Reuter, EdTech: Digital Solutions for Education, UBC Faculty of Medicine</p><p>Associate Director, Research Programs &amp; Administration<br>Shelly Au, Office of Research, UBC Faculty of Medicine</p><p>Executive Director<br>Dr. Michelle Wong, Canada’s Immuno-engineering and Biomanufacturing Hub and Office of Research, UBC Faculty of Medicine</p><p>Senior Producer, Creative and Distribution<br>Stephen Gillis, EdTech: Digital Solutions for Education, UBC Faculty of Medicine</p><p>Executive Producer<br>Zachary Rothman, EdTech: Digital Solutions for Education, UBC Faculty of Medicine</p><p>Subscribe to the show and other UBC Medicine Learning Network podcasts on Apple, Spotify, YouTube, or your favourite podcast platform.<br>&nbsp;</p><p>Episode Chapters</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>[00:00]</strong> – Introduction and episode overview</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>[01:36]</strong> – Personal pathways into AI and Health</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>[03:57]</strong> – Expediting breast cancer triaging</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>[08:02]</strong> – Scaling AI models across health settings</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>[09:28] </strong>– AI’s role in clinical care</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>[11:06] </strong>– Equity, access and marginalized populations</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>[12:38] </strong>– Education and training around AI best practices</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>[15:44] </strong>– Responsible use and UBC AI and Health Network</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>[22:29] </strong>– Sustainability and environmental responsibility</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>[25:50]</strong> – Improve patient experience and healthcare impact</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>[28:16]</strong> – Future vision</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>[31:03]</strong> – Closing remarks</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>[31:31]</strong> – Knowledge nugget<br><br><strong>Resources &amp; References</strong></p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Learn more about</p><p>o&nbsp;&nbsp; AI and Health Network: <a href="https://aihealth.med.ubc.ca/" rel="noopener noreferrer">https://aihealth.med.ubc.ca/</a></p><p>o&nbsp;&nbsp; Dr. Raymond Ng: <a href="https://www.cs.ubc.ca/~rng/" rel="noopener noreferrer">https://www.cs.ubc.ca/~rng/</a></p><p>o&nbsp;&nbsp; Dr. Anita Palepu: <a href="https://datascienceandhealth.ubc.ca/people/anita-palepu" rel="noopener noreferrer">https://datascienceandhealth.ubc.ca/people/anita-palepu</a></p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Ng, Raymond. <i>New data centres need to be built for the right reasons</i> (September 21, 2026).<a href="https://www.theglobeandmail.com/gift/6f8ae90c134057a9373d4be8ee82374724bed37d8e992ba94cb5f4fc67883df2/XGRAG74R35CNFK7CW7TDCZQ7RI/" rel="noopener noreferrer">https://www.theglobeandmail.com/gift/6f8ae90c134057a9373d4be8ee82374724bed37d8e992ba94cb5f4fc67883df2/XGRAG74R35CNFK7CW7TDCZQ7RI/</a>.</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Gondara, Lovedeep, et al. "<a href="https://www.mdpi.com/2504-4990/7/4/121" rel="noopener noreferrer">Small or large? zero-shot or finetuned? guiding language model choice for specialized applications in healthcare</a>." Machine Learning and Knowledge Extraction 7.4 (2025): 121.</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Al-Najafi, Dheyaa, et al. "<a href="https://link.springer.com/article/10.1186/s12909-026-09671-0" rel="noopener noreferrer">Psychometric performance and student perceptions of AI-versus student-generated multiple-choice questions: a single-center randomized controlled trial</a>." BMC Medical Education 26.1 (2026): 1376.<br><br>&nbsp;</p>
<p><p>The Vancouver Fraser Medical Program and the Vancouver Academic Campus of the University of British Columbia are situated on the traditional territory of the Musqueam, Squamish and Tsleil-Waututh peoples. <br /><br />
  The Southern Medical Program and the Okanagan Academic Campus of the University of British Columbia are situated on the territory of the Syilx Okanagan Nation. <br /><br />
  The Northern Medical Program and the University of Northern BC are situated on the traditional territory of the Lheidli T’enneh, part of the Dakelh (Carrier) First Nations. <br /><br />
  With respect to the Lekwungen peoples on whose traditional territory the Island Medical Program and the University of Victoria stand, and the Songhees, Esquimalt and WSÁNEĆ peoples whose historical relationships with the land continue to this day. <br /><br />
 We acknowledge our traditional hosts and honour their welcome and graciousness to the students who seek knowledge here. <br /><br />
  All rights reserved. Reproduction and distribution of this presentation without written permission from UBC Faculty of Medicine is strictly prohibited.</p>
<p><br />
 © UBC Medicine Learning Network 2026 </p>
<p> </p></p><br/> <p>Hosted by Simplecast, an AdsWizz company. See <a href="https://pcm.adswizz.com">pcm.adswizz.com</a> for information about our collection and use of personal data for advertising.</p>]]></content:encoded>
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      <itunes:title>Improving Care and Medical Education in the Age of AI</itunes:title>
      <itunes:author>Chantal Moore, Dr. Anita Palepu, Dr. Raymond Ng</itunes:author>
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      <itunes:summary>In this episode of Transforming Health Insights, we will learn from Dr. Raymond Ng and Dr. Anita Palepu about AI-driven decision support that is working on streamlining triaging for breast cancer patients in BC, with the goal of identifying high-risk patients earlier so they can access care.</itunes:summary>
      <itunes:subtitle>In this episode of Transforming Health Insights, we will learn from Dr. Raymond Ng and Dr. Anita Palepu about AI-driven decision support that is working on streamlining triaging for breast cancer patients in BC, with the goal of identifying high-risk patients earlier so they can access care.</itunes:subtitle>
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      <title>The Race to Reinvent Medicine, and Why Canada is Winning</title>
      <description><![CDATA[<p>In this episode, Dr. Pieter Cullis and Dr. Anna Blakney explore the rapidly advancing field of RNA-lipid nanoparticle (LNP) therapeutics and how this technology is enabling next-generation drug discovery platform with applications to precision or personalized medicines.</p><p>This technology, best known for its role in COVID-19 vaccines, is now being applied to personalized cancer vaccines, rare genetic diseases, gene editing and even anti-aging research. The conversation covers how these therapies are designed and delivered, including how patient-specific treatments can be developed and adapted on accelerated timelines, and the exciting potential for a new generation of safer, more-targeted cancer therapies.</p><p>They also examine the infrastructure required to move these innovations from lab to clinic, including biomanufacturing, regulatory pathways and the role of Canada’s research ecosystem. Their take-home message: RNA-LNP-based medicine represents a fundamental shift in how we treat diseases, and the shift is already underway with B.C. and Canada well positioned to help lead what comes next.</p><p>HOST: Chantal Moore, Scientific Communications and Engagement Strategist, UBC Office of Research</p><p>GUESTS: Dr. Anna Blakney, Assistant Professor, Michael Smith Laboratories and School of Biomedical Engineering at UBC and Dr. Pieter Cullis, Professor, Biochemistry and Molecular Biology, UBC Faculty of Medicine</p><p>Produced by<br>EdTech: Digital Solutions for Education and Office of Research, UBC Faculty of Medicine</p><p>Story Editors and Associate Producers<br>Neha Manjari Akella, Research Network Manager, MS Research Network, UBC Faculty of Medicine<br>Chantal Moore, Scientific Communications and Engagement Strategist, Office of Research, UBC Faculty of Medicine</p><p>Technical Production by<br>EdTech: Digital Solutions for Education, UBC Faculty of Medicine</p><p>Sound Recordist<br>Sam McGuinness, EdTech: Digital Solutions for Education, UBC Faculty of Medicine</p><p>Sound Editors<br>Sam McGuinness and Vanessa Reuter, EdTech: Digital Solutions for Education, UBC Faculty of Medicine</p><p>Associate Director, Research Programs &amp; Administration<br>Shelly Au, Office of Research, UBC Faculty of Medicine</p><p>Executive Director<br>Dr. Michelle Wong, Canada’s Immuno-engineering and Biomanufacturing Hub and Office of Research, UBC Faculty of Medicine</p><p>Senior Producer, Creative and Distribution<br>Stephen Gillis, EdTech: Digital Solutions for Education, UBC Faculty of Medicine</p><p>Executive Producer<br>Zachary Rothman, EdTech: Digital Solutions for Education, UBC Faculty of Medicine</p><p>Subscribe to the show and other UBC Medicine Learning Network podcasts on Apple, Spotify, YouTube, or your favourite podcast platform.<br><br>Episode Timestamps</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; [00:00] – Introduction and episode overview</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; [01:49] – The promise of RNA therapeutics</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; [02:18] – Applications in rare diseases</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; [06:14] – Personalized cancer vaccines</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; [07:33] – Advancing novel therapies</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; [11:29] – The AVENGER program</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; [14:38] – Building the foundation</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; [19:58] – Patient access and equity<br>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; [22:18] – Looking ahead</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; [25:55] – Canada’s strategic position and sovereignty</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; [27:13] – Drs. Cullis and Blakney’s personal pathways</p><p>&nbsp; &nbsp; &nbsp; &nbsp;[31:28] – Knowledge nugget<br>&nbsp;</p><p>Learn more about:</p><p>AVENGER: <a href="https://immunoengineeringhub.ca/programs/avenger/" rel="noopener noreferrer">https://immunoengineeringhub.ca/programs/avenger/</a></p><p>Dr. Anna Blakney: <a href="https://bme.ubc.ca/?directory=anna-blakney" rel="noopener noreferrer">https://bme.ubc.ca/?directory=anna-blakney</a></p><p>Dr. Pieter Cullis: <a href="https://lsi.ubc.ca/people/pieter-cullis/" rel="noopener noreferrer">https://lsi.ubc.ca/people/pieter-cullis/</a></p><p>Cullis, P., &amp; Blakney, A. <i>From COVID to cancer: Why Canada’s RNA vaccine leadership matters more than ever</i>. The Conversation (April 30, 2025). <a href="https://theconversation.com/from-covid-to-cancer-why-canadas-rna-vaccine-leadership-matters-more-than-ever-254692" rel="noopener noreferrer">https://theconversation.com/from-covid-to-cancer-why-canadas-rna-vaccine-leadership-matters-more-than-ever-254692</a>.</p><p>Canada’s Immuno-Engineering and Biomanufacturing Hub (CIEBH), a new UBC-led national research hub aimed at strengthening Canada’s pandemic preparedness and developing lifesaving new medicines that will transform the health of Canadians. <a href="https://immunoengineeringhub.ca/" rel="noopener noreferrer">https://immunoengineeringhub.ca/</a></p><p>Conflict of Interest Disclosure:</p><p>Dr. Pieter Cullis is a scientific entrepreneur, having co-founded over 10 biotechnology companies. He has financial holdings in Acuitas Therapeutics, NanoVation Therapeutics, Polymorphic BioSciences, Integrated NanoTherapeutics and SeraGene Therapeutics. He is Chair of NanoVation and CEO of Polymorphic and a member of the Board of Seragene.</p><p>Dr. Anna Blakney: Co-Founder: Syrina Therapeutics; Scientific Advisory Board: Genvax Technologies, Replicate Biosciences, Pasture Biosciences, TR1X Bio; Consultant: Cystic Fibrosis Foundation, Epitopea&nbsp;</p>
<p><p>The Vancouver Fraser Medical Program and the Vancouver Academic Campus of the University of British Columbia are situated on the traditional territory of the Musqueam, Squamish and Tsleil-Waututh peoples. <br /><br />
  The Southern Medical Program and the Okanagan Academic Campus of the University of British Columbia are situated on the territory of the Syilx Okanagan Nation. <br /><br />
  The Northern Medical Program and the University of Northern BC are situated on the traditional territory of the Lheidli T’enneh, part of the Dakelh (Carrier) First Nations. <br /><br />
  With respect to the Lekwungen peoples on whose traditional territory the Island Medical Program and the University of Victoria stand, and the Songhees, Esquimalt and WSÁNEĆ peoples whose historical relationships with the land continue to this day. <br /><br />
 We acknowledge our traditional hosts and honour their welcome and graciousness to the students who seek knowledge here. <br /><br />
  All rights reserved. Reproduction and distribution of this presentation without written permission from UBC Faculty of Medicine is strictly prohibited.</p>
<p><br />
 © UBC Medicine Learning Network 2026 </p>
<p> </p></p><br/> <p>Hosted by Simplecast, an AdsWizz company. See <a href="https://pcm.adswizz.com">pcm.adswizz.com</a> for information about our collection and use of personal data for advertising.</p>]]></description>
      <pubDate>Fri, 4 Sep 2026 14:00:00 +0000</pubDate>
      <author>stephen.gillis@ubc.ca (Chantal Moore, Dr. Anna Blakney, Dr. Pieter Cullis)</author>
      <link>https://transforming-health-insights.simplecast.com/episodes/the-race-to-reinvent-medicine-and-why-canada-is-winning-WXY1jfsX</link>
      <content:encoded><![CDATA[<p>In this episode, Dr. Pieter Cullis and Dr. Anna Blakney explore the rapidly advancing field of RNA-lipid nanoparticle (LNP) therapeutics and how this technology is enabling next-generation drug discovery platform with applications to precision or personalized medicines.</p><p>This technology, best known for its role in COVID-19 vaccines, is now being applied to personalized cancer vaccines, rare genetic diseases, gene editing and even anti-aging research. The conversation covers how these therapies are designed and delivered, including how patient-specific treatments can be developed and adapted on accelerated timelines, and the exciting potential for a new generation of safer, more-targeted cancer therapies.</p><p>They also examine the infrastructure required to move these innovations from lab to clinic, including biomanufacturing, regulatory pathways and the role of Canada’s research ecosystem. Their take-home message: RNA-LNP-based medicine represents a fundamental shift in how we treat diseases, and the shift is already underway with B.C. and Canada well positioned to help lead what comes next.</p><p>HOST: Chantal Moore, Scientific Communications and Engagement Strategist, UBC Office of Research</p><p>GUESTS: Dr. Anna Blakney, Assistant Professor, Michael Smith Laboratories and School of Biomedical Engineering at UBC and Dr. Pieter Cullis, Professor, Biochemistry and Molecular Biology, UBC Faculty of Medicine</p><p>Produced by<br>EdTech: Digital Solutions for Education and Office of Research, UBC Faculty of Medicine</p><p>Story Editors and Associate Producers<br>Neha Manjari Akella, Research Network Manager, MS Research Network, UBC Faculty of Medicine<br>Chantal Moore, Scientific Communications and Engagement Strategist, Office of Research, UBC Faculty of Medicine</p><p>Technical Production by<br>EdTech: Digital Solutions for Education, UBC Faculty of Medicine</p><p>Sound Recordist<br>Sam McGuinness, EdTech: Digital Solutions for Education, UBC Faculty of Medicine</p><p>Sound Editors<br>Sam McGuinness and Vanessa Reuter, EdTech: Digital Solutions for Education, UBC Faculty of Medicine</p><p>Associate Director, Research Programs &amp; Administration<br>Shelly Au, Office of Research, UBC Faculty of Medicine</p><p>Executive Director<br>Dr. Michelle Wong, Canada’s Immuno-engineering and Biomanufacturing Hub and Office of Research, UBC Faculty of Medicine</p><p>Senior Producer, Creative and Distribution<br>Stephen Gillis, EdTech: Digital Solutions for Education, UBC Faculty of Medicine</p><p>Executive Producer<br>Zachary Rothman, EdTech: Digital Solutions for Education, UBC Faculty of Medicine</p><p>Subscribe to the show and other UBC Medicine Learning Network podcasts on Apple, Spotify, YouTube, or your favourite podcast platform.<br><br>Episode Timestamps</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; [00:00] – Introduction and episode overview</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; [01:49] – The promise of RNA therapeutics</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; [02:18] – Applications in rare diseases</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; [06:14] – Personalized cancer vaccines</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; [07:33] – Advancing novel therapies</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; [11:29] – The AVENGER program</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; [14:38] – Building the foundation</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; [19:58] – Patient access and equity<br>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; [22:18] – Looking ahead</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; [25:55] – Canada’s strategic position and sovereignty</p><p>·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; [27:13] – Drs. Cullis and Blakney’s personal pathways</p><p>&nbsp; &nbsp; &nbsp; &nbsp;[31:28] – Knowledge nugget<br>&nbsp;</p><p>Learn more about:</p><p>AVENGER: <a href="https://immunoengineeringhub.ca/programs/avenger/" rel="noopener noreferrer">https://immunoengineeringhub.ca/programs/avenger/</a></p><p>Dr. Anna Blakney: <a href="https://bme.ubc.ca/?directory=anna-blakney" rel="noopener noreferrer">https://bme.ubc.ca/?directory=anna-blakney</a></p><p>Dr. Pieter Cullis: <a href="https://lsi.ubc.ca/people/pieter-cullis/" rel="noopener noreferrer">https://lsi.ubc.ca/people/pieter-cullis/</a></p><p>Cullis, P., &amp; Blakney, A. <i>From COVID to cancer: Why Canada’s RNA vaccine leadership matters more than ever</i>. The Conversation (April 30, 2025). <a href="https://theconversation.com/from-covid-to-cancer-why-canadas-rna-vaccine-leadership-matters-more-than-ever-254692" rel="noopener noreferrer">https://theconversation.com/from-covid-to-cancer-why-canadas-rna-vaccine-leadership-matters-more-than-ever-254692</a>.</p><p>Canada’s Immuno-Engineering and Biomanufacturing Hub (CIEBH), a new UBC-led national research hub aimed at strengthening Canada’s pandemic preparedness and developing lifesaving new medicines that will transform the health of Canadians. <a href="https://immunoengineeringhub.ca/" rel="noopener noreferrer">https://immunoengineeringhub.ca/</a></p><p>Conflict of Interest Disclosure:</p><p>Dr. Pieter Cullis is a scientific entrepreneur, having co-founded over 10 biotechnology companies. He has financial holdings in Acuitas Therapeutics, NanoVation Therapeutics, Polymorphic BioSciences, Integrated NanoTherapeutics and SeraGene Therapeutics. He is Chair of NanoVation and CEO of Polymorphic and a member of the Board of Seragene.</p><p>Dr. Anna Blakney: Co-Founder: Syrina Therapeutics; Scientific Advisory Board: Genvax Technologies, Replicate Biosciences, Pasture Biosciences, TR1X Bio; Consultant: Cystic Fibrosis Foundation, Epitopea&nbsp;</p>
<p><p>The Vancouver Fraser Medical Program and the Vancouver Academic Campus of the University of British Columbia are situated on the traditional territory of the Musqueam, Squamish and Tsleil-Waututh peoples. <br /><br />
  The Southern Medical Program and the Okanagan Academic Campus of the University of British Columbia are situated on the territory of the Syilx Okanagan Nation. <br /><br />
  The Northern Medical Program and the University of Northern BC are situated on the traditional territory of the Lheidli T’enneh, part of the Dakelh (Carrier) First Nations. <br /><br />
  With respect to the Lekwungen peoples on whose traditional territory the Island Medical Program and the University of Victoria stand, and the Songhees, Esquimalt and WSÁNEĆ peoples whose historical relationships with the land continue to this day. <br /><br />
 We acknowledge our traditional hosts and honour their welcome and graciousness to the students who seek knowledge here. <br /><br />
  All rights reserved. Reproduction and distribution of this presentation without written permission from UBC Faculty of Medicine is strictly prohibited.</p>
<p><br />
 © UBC Medicine Learning Network 2026 </p>
<p> </p></p><br/> <p>Hosted by Simplecast, an AdsWizz company. See <a href="https://pcm.adswizz.com">pcm.adswizz.com</a> for information about our collection and use of personal data for advertising.</p>]]></content:encoded>
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      <itunes:title>The Race to Reinvent Medicine, and Why Canada is Winning</itunes:title>
      <itunes:author>Chantal Moore, Dr. Anna Blakney, Dr. Pieter Cullis</itunes:author>
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      <itunes:duration>00:33:18</itunes:duration>
      <itunes:summary>In this episode, Dr. Pieter Cullis and Dr. Anna Blakney explore the rapidly advancing field of RNA-lipid nanoparticle (LNP) therapeutics and how this technology is enabling next-generation drug discovery platform with applications to precision or personalized medicines. This technology, best known for its role in COVID-19 vaccines, is now being applied to personalized cancer vaccines, rare genetic diseases, gene editing and even anti-aging research.  

The conversation covers how these therapies are designed and delivered, including how patient-specific treatments can be developed and adapted on accelerated timelines, and the exciting potential for a new generation of safer, more-targeted cancer therapies. They also examine the infrastructure required to move these innovations from lab to clinic, including biomanufacturing, regulatory pathways and the role of Canada’s research ecosystem.  Their take-home message: RNA-LNP-based medicine represents a fundamental shift in how we treat diseases, and the shift is already underway with B.C. and Canada well positioned to help lead what comes next. 

HOST: Chantal Moore, Scientific Communications and Engagement Strategist, UBC Office of Research
GUESTS: Dr. Anna Blakney, Assistant Professor, Michael Smith Laboratories and School of Biomedical Engineering at UBC
                 Dr. Pieter Cullis, Professor, Biochemistry and Molecular Biology, UBC Faculty of Medicine

Produced by
EdTech: Digital Solutions for Education, UBC Faculty of Medicine and Office of Research, UBC Faculty of Medicine

Story Editors and Associate Producers
Neha Manjari Akella, Research Network Manager
Chantal Moore, Office of Research, UBC Faculty of Medicine

Technical Production by
EdTech: Digital Solutions for Education, UBC Faculty of Medicine

Sound Recordist
Sam McGuinness

Sound Editors
Sam McGuinness and Vanessa Reuter

Associate Director, Research Programs &amp; Administration
Shelly Au, Office of Research, UBC Faculty of Medicine

Senior Producer, Creative and Distribution
Stephen Gillis, EdTech: Digital Solutions for Education, UBC Faculty of Medicine

Executive Producers
Dr. Michelle Wong, Office of Research, UBC Faculty of Medicine
Zachary Rothman, EdTech: Digital Solutions for Education, UBC Faculty of Medicine

Subscribe to the show and other UBC Medicine Learning Network podcasts on Apple, Spotify, YouTube, or your favourite podcast platform.</itunes:summary>
      <itunes:subtitle>In this episode, Dr. Pieter Cullis and Dr. Anna Blakney explore the rapidly advancing field of RNA-lipid nanoparticle (LNP) therapeutics and how this technology is enabling next-generation drug discovery platform with applications to precision or personalized medicines. This technology, best known for its role in COVID-19 vaccines, is now being applied to personalized cancer vaccines, rare genetic diseases, gene editing and even anti-aging research.  

The conversation covers how these therapies are designed and delivered, including how patient-specific treatments can be developed and adapted on accelerated timelines, and the exciting potential for a new generation of safer, more-targeted cancer therapies. They also examine the infrastructure required to move these innovations from lab to clinic, including biomanufacturing, regulatory pathways and the role of Canada’s research ecosystem.  Their take-home message: RNA-LNP-based medicine represents a fundamental shift in how we treat diseases, and the shift is already underway with B.C. and Canada well positioned to help lead what comes next. 

HOST: Chantal Moore, Scientific Communications and Engagement Strategist, UBC Office of Research
GUESTS: Dr. Anna Blakney, Assistant Professor, Michael Smith Laboratories and School of Biomedical Engineering at UBC
                 Dr. Pieter Cullis, Professor, Biochemistry and Molecular Biology, UBC Faculty of Medicine

Produced by
EdTech: Digital Solutions for Education, UBC Faculty of Medicine and Office of Research, UBC Faculty of Medicine

Story Editors and Associate Producers
Neha Manjari Akella, Research Network Manager
Chantal Moore, Office of Research, UBC Faculty of Medicine

Technical Production by
EdTech: Digital Solutions for Education, UBC Faculty of Medicine

Sound Recordist
Sam McGuinness

Sound Editors
Sam McGuinness and Vanessa Reuter

Associate Director, Research Programs &amp; Administration
Shelly Au, Office of Research, UBC Faculty of Medicine

Senior Producer, Creative and Distribution
Stephen Gillis, EdTech: Digital Solutions for Education, UBC Faculty of Medicine

Executive Producers
Dr. Michelle Wong, Office of Research, UBC Faculty of Medicine
Zachary Rothman, EdTech: Digital Solutions for Education, UBC Faculty of Medicine

Subscribe to the show and other UBC Medicine Learning Network podcasts on Apple, Spotify, YouTube, or your favourite podcast platform.</itunes:subtitle>
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      <description><![CDATA[Turning biomedical discoveries into real-world care one story at a time. From UBC Faculty of Medicine, Office of Research, this is the Transforming Health Insights podcast, bringing you the stories behind the science. We’re sharing the people and ideas transforming health in B.C., making complex science accessible for everyone. From life-saving RNA breakthroughs, to AI helping to identify high-risk cancer patients earlier, to the next generation of cell therapies—hear it straight from the incredibly dedicated people making it happen. Featuring researchers, clinicians, patients and partners. 

Subscribe today and don't miss the upcoming podcast launch on all your favourite podcast platforms.  The Vancouver Fraser Medical Program and the Vancouver Academic Campus
of the University of British Columbia are situated on the traditional
territory of the Musqueam, Squamish and Tsleil-Waututh peoples.
The Southern Medical Program and the Okanagan Academic Campus of the
University of British Columbia are situated on the territory of the
Syilx Okanagan Nation.
The Northern Medical Program and the University of Northern BC are
situated on the traditional territory of the Lheidli T’enneh, part of
the Dakelh (Carrier) First Nations.
With respect to the Lekwungen peoples on whose traditional territory the
Island Medical Program and the University of Victoria stand, and the
Songhees, Esquimalt and WSÁNEĆ peoples whose historical relationships
with the land continue to this day.
We acknowledge our traditional hosts and honour their welcome and
graciousness to the students who seek knowledge here.
All rights reserved. Reproduction and distribution of this presentation
without written permission from UBC Faculty of Medicine is strictly
prohibited.

© UBC Medicine Learning Network 2026

Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com
for information about our collection and use of personal data for
advertising.
]]></description>
      <pubDate>Thu, 2 Apr 2026 17:10:18 +0000</pubDate>
      <author>stephen.gillis@ubc.ca (stephen.gillis@ubc.ca)</author>
      <link>https://transforming-health-insights.simplecast.com/episodes/transforming-health-insights-podcast-season-1-teaser-wyVrw35_</link>
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      <itunes:title>Transforming Health Insights Podcast - Season 1 Teaser</itunes:title>
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      <itunes:summary>Turning biomedical discoveries into real-world care one story at a time. From UBC Faculty of Medicine, Office of Research, this is the Transforming Health Insights podcast, bringing you the stories behind the science. We’re sharing the people and ideas transforming health in B.C., making complex science accessible for everyone. From life-saving RNA breakthroughs, to AI helping to identify high-risk cancer patients earlier, to the next generation of cell therapies—hear it straight from the incredibly dedicated people making it happen. Featuring researchers, clinicians, patients and partners. 

Subscribe today and don&apos;t miss the upcoming podcast launch on all your favourite podcast platforms. </itunes:summary>
      <itunes:subtitle>Turning biomedical discoveries into real-world care one story at a time. From UBC Faculty of Medicine, Office of Research, this is the Transforming Health Insights podcast, bringing you the stories behind the science. We’re sharing the people and ideas transforming health in B.C., making complex science accessible for everyone. From life-saving RNA breakthroughs, to AI helping to identify high-risk cancer patients earlier, to the next generation of cell therapies—hear it straight from the incredibly dedicated people making it happen. Featuring researchers, clinicians, patients and partners. 

Subscribe today and don&apos;t miss the upcoming podcast launch on all your favourite podcast platforms. </itunes:subtitle>
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