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    <title>Investigating HLH</title>
    <description>Investigating HLH, brought to you by Sobi Inc., is a podcast that takes a deep dive into the complex world of hemophagocytic lymphohistiocytosis, or HLH. As a rare and fatal disease that was once considered incurable, HLH presents with a range of severe signs and symptoms that make diagnosis difficult. Join us as we discuss insights about HLH from all angles with various experts in the field of hematology-oncology who have helped to advance the understanding and treatment of this devastating disease. When treating patients with HLH, knowledge is power—because knowing what to look for can save lives.</description>
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    <pubDate>Tue, 23 Sep 2025 04:00:00 +0000</pubDate>
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    <itunes:summary>Investigating HLH, brought to you by Sobi Inc., is a podcast that takes a deep dive into the complex world of hemophagocytic lymphohistiocytosis, or HLH. As a rare and fatal disease that was once considered incurable, HLH presents with a range of severe signs and symptoms that make diagnosis difficult. Join us as we discuss insights about HLH from all angles with various experts in the field of hematology-oncology who have helped to advance the understanding and treatment of this devastating disease. When treating patients with HLH, knowledge is power—because knowing what to look for can save lives.</itunes:summary>
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      <title>What is MAS?</title>
      <description><![CDATA[<p>In this episode of Investigating HLH, Adam Narloch speaks with Dr  Daniella Schwartz and Dr Randy Cron to discuss a rare, potentially fatal syndrome characterized  by hyperinflammation⎯macrophage activation syndrome (MAS). Dr Daniella Schwartz is a rheumatologist in Pittsburgh, Pennsylvania, and is affiliated with the University of Pittsburgh  Medical Center (UPMC) Presbyterian Shadyside and the UPMC Magee-Womens Hospital. Dr  Randy Cron is a pediatric rheumatologist at Children’s Hospital of Alabama at the University of  Alabama (UAB). Hear from these 2 experts about MAS⎯a subtype of hemophagocytic lymphohistiocytosis (HLH) that can occur in rheumatic diseases such as SAll's disease, including  systemic juvenile idiopathic arthritis (sJIA).</p><p>Follow Us</p><ul><li>YouTube <a href="https://www.youtube.com/@Sobi-Pharma">@Sobi-Pharma</a></li><li>Linkedin <a href="https://www.linkedin.com/company/sobi/">@Sobi</a></li></ul><p><i>Presented by Sobi Inc.</i></p><p><a href="https://www.sobi.com/usa/en"><i>https://www.sobi.com/usa/en</i></a></p>
<p><p>©2023 Sobi, Inc. All rights reserved. NP-32204 12/23&nbsp;</p></p><br/> <p>Hosted by Simplecast, an AdsWizz company. See <a href="https://pcm.adswizz.com">pcm.adswizz.com</a> for information about our collection and use of personal data for advertising.</p>]]></description>
      <pubDate>Tue, 23 Sep 2025 04:00:00 +0000</pubDate>
      <author>stories@amazemedialabs.com (Dr. Daniella Schwartz, Dr. Randy Cron, Adam Narloch)</author>
      <link>https://investigating-hlh.simplecast.com/episodes/what-is-mas-QcI03qv3</link>
      <content:encoded><![CDATA[<p>In this episode of Investigating HLH, Adam Narloch speaks with Dr  Daniella Schwartz and Dr Randy Cron to discuss a rare, potentially fatal syndrome characterized  by hyperinflammation⎯macrophage activation syndrome (MAS). Dr Daniella Schwartz is a rheumatologist in Pittsburgh, Pennsylvania, and is affiliated with the University of Pittsburgh  Medical Center (UPMC) Presbyterian Shadyside and the UPMC Magee-Womens Hospital. Dr  Randy Cron is a pediatric rheumatologist at Children’s Hospital of Alabama at the University of  Alabama (UAB). Hear from these 2 experts about MAS⎯a subtype of hemophagocytic lymphohistiocytosis (HLH) that can occur in rheumatic diseases such as SAll's disease, including  systemic juvenile idiopathic arthritis (sJIA).</p><p>Follow Us</p><ul><li>YouTube <a href="https://www.youtube.com/@Sobi-Pharma">@Sobi-Pharma</a></li><li>Linkedin <a href="https://www.linkedin.com/company/sobi/">@Sobi</a></li></ul><p><i>Presented by Sobi Inc.</i></p><p><a href="https://www.sobi.com/usa/en"><i>https://www.sobi.com/usa/en</i></a></p>
<p><p>©2023 Sobi, Inc. All rights reserved. NP-32204 12/23&nbsp;</p></p><br/> <p>Hosted by Simplecast, an AdsWizz company. See <a href="https://pcm.adswizz.com">pcm.adswizz.com</a> for information about our collection and use of personal data for advertising.</p>]]></content:encoded>
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      <itunes:title>What is MAS?</itunes:title>
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      <itunes:summary>Adam Narloch speaks with Dr. Daniella Schwartz and Dr. Randy Cron about recognizing and managing MAS, a rare subtype of HLH in rheumatic diseases.</itunes:summary>
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      <title>Monitoring Treatment Response</title>
      <description><![CDATA[<p>Kari Magee speaks with Dr Bethany Verkamp to discuss her recent research on evaluating treatment response to etoposide-based treatment in patients with HLH. Dr Verkamp is a hematology/oncology fellow in the Cancer and Blood Diseases Institute at Cincinnati Children's Hospital. Hear from Dr Verkamp about her research, findings, and important considerations for assessing patient response to first-line etoposide-based HLH therapy.</p><p>Follow Us</p><ul><li>YouTube <a href="https://www.youtube.com/@Sobi-Pharma">@Sobi-Pharma</a></li><li>Linkedin <a href="https://www.linkedin.com/company/sobi/">@Sobi</a></li></ul><p><i>Presented by Sobi Inc.</i></p><p><a href="https://www.sobi.com/usa/en"><i>https://www.sobi.com/usa/en</i></a></p>
<p><p>©2023 Sobi, Inc. All rights reserved. NP-32204 12/23&nbsp;</p></p><br/> <p>Hosted by Simplecast, an AdsWizz company. See <a href="https://pcm.adswizz.com">pcm.adswizz.com</a> for information about our collection and use of personal data for advertising.</p>]]></description>
      <pubDate>Tue, 25 Feb 2025 05:00:00 +0000</pubDate>
      <author>stories@amazemedialabs.com (Kari Magee, Dr Bethany Verkamp)</author>
      <link>https://investigating-hlh.simplecast.com/episodes/monitoring-treatment-response-Z5mqG9p9</link>
      <content:encoded><![CDATA[<p>Kari Magee speaks with Dr Bethany Verkamp to discuss her recent research on evaluating treatment response to etoposide-based treatment in patients with HLH. Dr Verkamp is a hematology/oncology fellow in the Cancer and Blood Diseases Institute at Cincinnati Children's Hospital. Hear from Dr Verkamp about her research, findings, and important considerations for assessing patient response to first-line etoposide-based HLH therapy.</p><p>Follow Us</p><ul><li>YouTube <a href="https://www.youtube.com/@Sobi-Pharma">@Sobi-Pharma</a></li><li>Linkedin <a href="https://www.linkedin.com/company/sobi/">@Sobi</a></li></ul><p><i>Presented by Sobi Inc.</i></p><p><a href="https://www.sobi.com/usa/en"><i>https://www.sobi.com/usa/en</i></a></p>
<p><p>©2023 Sobi, Inc. All rights reserved. NP-32204 12/23&nbsp;</p></p><br/> <p>Hosted by Simplecast, an AdsWizz company. See <a href="https://pcm.adswizz.com">pcm.adswizz.com</a> for information about our collection and use of personal data for advertising.</p>]]></content:encoded>
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      <itunes:title>Monitoring Treatment Response</itunes:title>
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      <itunes:duration>00:15:53</itunes:duration>
      <itunes:summary>Kari Magee speaks with Dr Bethany Verkamp to discuss her recent research on evaluating treatment response to etoposide-based treatment in patients with hemophagocytic lymphohistiocytosis (HLH).</itunes:summary>
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      <title>Treating HLH</title>
      <description><![CDATA[<p>Adam Narloch is joined by Dr. Saara Kaviany and Dr. Blachy J. Dávila Saldaña for a discussion about treating patients with HLH. Dr Kaviany is a pediatric hematologist-oncologist and an assistant professor of pediatrics at University of Chicago Medicine. Dr Saldaña is also a pediatric hematologist-oncologist and an associate professor of pediatrics at George Washington University. Hear from these 2 experts about the overall treatment goals and strategies for patients with HLH.</p><p>Follow Us</p><ul><li>YouTube <a href="https://www.youtube.com/@Sobi-Pharma">@Sobi-Pharma</a></li><li>Linkedin <a href="https://www.linkedin.com/company/sobi/">@Sobi</a></li></ul><p><i>Presented by Sobi Inc.</i></p><p><a href="http://www.sobi.com"><i>www.sobi.com</i></a></p>
<p><p>©2023 Sobi, Inc. All rights reserved. NP-32204 12/23&nbsp;</p></p><br/> <p>Hosted by Simplecast, an AdsWizz company. See <a href="https://pcm.adswizz.com">pcm.adswizz.com</a> for information about our collection and use of personal data for advertising.</p>]]></description>
      <pubDate>Wed, 5 Jun 2024 04:00:00 +0000</pubDate>
      <author>stories@amazemedialabs.com (Adam Narloch, Saara Kaviany, Blachy J. Dávila Saldaña)</author>
      <link>https://investigating-hlh.simplecast.com/episodes/treating-hlh-OQMAoQrW</link>
      <content:encoded><![CDATA[<p>Adam Narloch is joined by Dr. Saara Kaviany and Dr. Blachy J. Dávila Saldaña for a discussion about treating patients with HLH. Dr Kaviany is a pediatric hematologist-oncologist and an assistant professor of pediatrics at University of Chicago Medicine. Dr Saldaña is also a pediatric hematologist-oncologist and an associate professor of pediatrics at George Washington University. Hear from these 2 experts about the overall treatment goals and strategies for patients with HLH.</p><p>Follow Us</p><ul><li>YouTube <a href="https://www.youtube.com/@Sobi-Pharma">@Sobi-Pharma</a></li><li>Linkedin <a href="https://www.linkedin.com/company/sobi/">@Sobi</a></li></ul><p><i>Presented by Sobi Inc.</i></p><p><a href="http://www.sobi.com"><i>www.sobi.com</i></a></p>
<p><p>©2023 Sobi, Inc. All rights reserved. NP-32204 12/23&nbsp;</p></p><br/> <p>Hosted by Simplecast, an AdsWizz company. See <a href="https://pcm.adswizz.com">pcm.adswizz.com</a> for information about our collection and use of personal data for advertising.</p>]]></content:encoded>
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      <itunes:title>Treating HLH</itunes:title>
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      <itunes:summary>Dr. Saara Kaviany and Dr. Blachy J. Dávila Saldaña discuss the overall treatment goals and strategies for patients with HLH.</itunes:summary>
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      <title>Diagnosing HLH</title>
      <description><![CDATA[<p>Adam Narloch speaks with Dr Ashish Kumar and Dr Scott Canna to discuss the challenges involved with diagnosing and managing HLH. Dr Kumar is a pediatric hematologist- oncologist, and a director of the Histiocytosis Center at Cincinnati Children's Hospital. Dr Scott Canna is a pediatric rheumatologist and an Assistant Professor of Pediatrics at Children’s Hospital of Philadelphia. Hear from these 2 experts about why a prompt diagnosis is critical for patients with HLH—and why it can be so difficult to achieve.</p><p>Follow Us</p><ul><li>YouTube <a href="https://www.youtube.com/@Sobi-Pharma">@Sobi-Pharma</a></li><li>Linkedin <a href="https://www.linkedin.com/company/sobi/">@Sobi</a></li></ul><p><i>Presented by Sobi Inc.</i></p><p><a href="https://www.sobi.com/usa/en"><i>https://www.sobi.com/usa/en</i></a></p>
<p><p>©2023 Sobi, Inc. All rights reserved. NP-32204 12/23&nbsp;</p></p><br/> <p>Hosted by Simplecast, an AdsWizz company. See <a href="https://pcm.adswizz.com">pcm.adswizz.com</a> for information about our collection and use of personal data for advertising.</p>]]></description>
      <pubDate>Wed, 15 May 2024 04:00:00 +0000</pubDate>
      <author>stories@amazemedialabs.com (Adam Narloch, Ashish Kumar, Scott Canna)</author>
      <link>https://investigating-hlh.simplecast.com/episodes/diagnosing-hlh-oczCwjrp</link>
      <content:encoded><![CDATA[<p>Adam Narloch speaks with Dr Ashish Kumar and Dr Scott Canna to discuss the challenges involved with diagnosing and managing HLH. Dr Kumar is a pediatric hematologist- oncologist, and a director of the Histiocytosis Center at Cincinnati Children's Hospital. Dr Scott Canna is a pediatric rheumatologist and an Assistant Professor of Pediatrics at Children’s Hospital of Philadelphia. Hear from these 2 experts about why a prompt diagnosis is critical for patients with HLH—and why it can be so difficult to achieve.</p><p>Follow Us</p><ul><li>YouTube <a href="https://www.youtube.com/@Sobi-Pharma">@Sobi-Pharma</a></li><li>Linkedin <a href="https://www.linkedin.com/company/sobi/">@Sobi</a></li></ul><p><i>Presented by Sobi Inc.</i></p><p><a href="https://www.sobi.com/usa/en"><i>https://www.sobi.com/usa/en</i></a></p>
<p><p>©2023 Sobi, Inc. All rights reserved. NP-32204 12/23&nbsp;</p></p><br/> <p>Hosted by Simplecast, an AdsWizz company. See <a href="https://pcm.adswizz.com">pcm.adswizz.com</a> for information about our collection and use of personal data for advertising.</p>]]></content:encoded>
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      <itunes:title>Diagnosing HLH</itunes:title>
      <itunes:author>Adam Narloch, Ashish Kumar, Scott Canna</itunes:author>
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      <itunes:summary>Adam Narloch speaks with Dr Ashish Kumar and Dr Scott Canna to discuss the challenges involved with diagnosing and managing HLH.</itunes:summary>
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      <title>Introduction to HLH</title>
      <description><![CDATA[<p>Adam Narloch speaks with Dr Michelle Hermiston to discuss the history of HLH and advances in understanding this rare disease. Dr Hermiston is a pediatric hematologist-oncologist, a bone marrow transplant specialist, and the director of the Pediatric Immunotherapy Program at UCSF Benioff Children’s Hospital. Join us as we start our journey into the world of HLH!</p><p>Follow Us</p><ul><li>YouTube <a href="https://www.youtube.com/@Sobi-Pharma">@Sobi-Pharma</a></li><li>Linkedin <a href="https://www.linkedin.com/company/sobi/">@Sobi</a></li></ul><p><i>Presented by Sobi Inc.</i></p><p><a href="https://www.sobi.com/usa/en"><i>https://www.sobi.com/usa/en</i></a></p>
<p><p>©2023 Sobi, Inc. All rights reserved. NP-32204 12/23&nbsp;</p></p><br/> <p>Hosted by Simplecast, an AdsWizz company. See <a href="https://pcm.adswizz.com">pcm.adswizz.com</a> for information about our collection and use of personal data for advertising.</p>]]></description>
      <pubDate>Mon, 22 Apr 2024 04:00:00 +0000</pubDate>
      <author>stories@amazemedialabs.com (Adam Narloch, Michelle Hermiston)</author>
      <link>https://investigating-hlh.simplecast.com/episodes/introduction-to-hlh-bu4exrhl-cXX__diB</link>
      <content:encoded><![CDATA[<p>Adam Narloch speaks with Dr Michelle Hermiston to discuss the history of HLH and advances in understanding this rare disease. Dr Hermiston is a pediatric hematologist-oncologist, a bone marrow transplant specialist, and the director of the Pediatric Immunotherapy Program at UCSF Benioff Children’s Hospital. Join us as we start our journey into the world of HLH!</p><p>Follow Us</p><ul><li>YouTube <a href="https://www.youtube.com/@Sobi-Pharma">@Sobi-Pharma</a></li><li>Linkedin <a href="https://www.linkedin.com/company/sobi/">@Sobi</a></li></ul><p><i>Presented by Sobi Inc.</i></p><p><a href="https://www.sobi.com/usa/en"><i>https://www.sobi.com/usa/en</i></a></p>
<p><p>©2023 Sobi, Inc. All rights reserved. NP-32204 12/23&nbsp;</p></p><br/> <p>Hosted by Simplecast, an AdsWizz company. See <a href="https://pcm.adswizz.com">pcm.adswizz.com</a> for information about our collection and use of personal data for advertising.</p>]]></content:encoded>
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      <itunes:title>Introduction to HLH</itunes:title>
      <itunes:author>Adam Narloch, Michelle Hermiston</itunes:author>
      <itunes:duration>00:23:00</itunes:duration>
      <itunes:summary>Adam Narloch speaks with Dr. Michelle Hermiston to discuss the history of HLH and advances that have been made in understanding this rare disease. </itunes:summary>
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      <title>An Introduction to HLH</title>
      <description><![CDATA[<p>In this episode of <i>Investigating HLH</i>, Adam Narloch, a Thought Leader Liaison at Sobi, speaks with Dr Michelle Hermiston to discuss the history of HLH and advances that have been made in understanding this rare disease. Dr Hermiston is a pediatric hematologist-oncologist, a bone marrow transplant specialist, and the director of the Pediatric Immunotherapy Program at UCSF Benioff Children’s Hospital. Join us as we start our journey into the world of HLH!</p><p>Follow Us</p><ul><li>YouTube <a href="https://www.youtube.com/c/Sobi-Pharma">@Sobi-Pharma</a></li><li>LinkedIn <a href="https://www.linkedin.com/company/sobi/">@Sobi</a></li></ul><p><i>Presented by Sobi Inc.</i></p><p><a href="https://www.sobi.com/usa/en">https://www.sobi.com/usa/en</a></p>
<p><p>©2023 Sobi, Inc. All rights reserved. NP-32204 12/23&nbsp;</p></p><br/> <p>Hosted by Simplecast, an AdsWizz company. See <a href="https://pcm.adswizz.com">pcm.adswizz.com</a> for information about our collection and use of personal data for advertising.</p>]]></description>
      <pubDate>Tue, 14 Nov 2023 18:22:35 +0000</pubDate>
      <author>stories@amazemedialabs.com (Adam Narloch, Dr Michelle Hermiston)</author>
      <link>https://investigating-hlh.simplecast.com/episodes/introduction-to-hlh-nO50NkFJ</link>
      <content:encoded><![CDATA[<p>In this episode of <i>Investigating HLH</i>, Adam Narloch, a Thought Leader Liaison at Sobi, speaks with Dr Michelle Hermiston to discuss the history of HLH and advances that have been made in understanding this rare disease. Dr Hermiston is a pediatric hematologist-oncologist, a bone marrow transplant specialist, and the director of the Pediatric Immunotherapy Program at UCSF Benioff Children’s Hospital. Join us as we start our journey into the world of HLH!</p><p>Follow Us</p><ul><li>YouTube <a href="https://www.youtube.com/c/Sobi-Pharma">@Sobi-Pharma</a></li><li>LinkedIn <a href="https://www.linkedin.com/company/sobi/">@Sobi</a></li></ul><p><i>Presented by Sobi Inc.</i></p><p><a href="https://www.sobi.com/usa/en">https://www.sobi.com/usa/en</a></p>
<p><p>©2023 Sobi, Inc. All rights reserved. NP-32204 12/23&nbsp;</p></p><br/> <p>Hosted by Simplecast, an AdsWizz company. See <a href="https://pcm.adswizz.com">pcm.adswizz.com</a> for information about our collection and use of personal data for advertising.</p>]]></content:encoded>
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      <itunes:title>An Introduction to HLH</itunes:title>
      <itunes:author>Adam Narloch, Dr Michelle Hermiston</itunes:author>
      <itunes:duration>00:00:41</itunes:duration>
      <itunes:summary>Join us with Dr Michelle Hermiston to discuss the history of hemophagocytic lymphohistiocytosis (HLH) and advances in our knowledge of this rare disease.</itunes:summary>
      <itunes:subtitle>Join us with Dr Michelle Hermiston to discuss the history of hemophagocytic lymphohistiocytosis (HLH) and advances in our knowledge of this rare disease.</itunes:subtitle>
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