a16z Live

How Startups are Fixing Healthcare Friction

content+a16zpodcast@a16z.com (Trey Holterman, Christophe Rimann, David Haber) — Wed, 25 Jun 2025 10:00:00 +0000

What if the biggest lever for improving U.S. healthcare isn’t clinical, but operational?

In this episode, recorded live at New York Tech Week, a16z General Partner David Haber speaks with Trey Holterman (Tennr) and Christophe Rimann (Camber), two founders tackling the core infrastructure problems slowing healthcare down - from broken referral handoffs to denied insurance claims.

They discuss building trust in high-stakes workflows, how better incentives (not just better tech) drive adoption, and why the most defensible products aren’t just smart - they work 97%+ of the time.

Plus: advice for founders, the cultural edge of New York startups, and what they’d fix first if they ran HHS.

Timecodes:

00:00 Introduction to Healthcare Payment Innovation

00:48 Meet the Founders: Trey Holman and Christophe Reman

02:31 The Broken Healthcare System: Identifying the Problems

03:47 The Why Now: Technological and Market Shifts

05:29 Understanding the Customers and Their Needs

06:34 Challenges and Misconceptions in Healthcare Technology

08:31 Building a Company in New York City

10:29 Leveraging AI and Technology for Better Outcomes

12:29 Defensibility and Differentiation in Healthcare Solutions

15:28 Impact on Providers and Patients

18:09 Advice for Aspiring Healthcare Entrepreneurs

23:17 Conclusion and Final Thoughts

Resources:

Find David on X: https://x.com/dhaber

Find Trey on LinkedIn: https://www.linkedin.com/in/trey-holterman

Find Christophe on X: https://www.linkedin.com/in/christopherimann/

What Comes After Mobile? Meta’s Andrew Bosworth on AI and Consumer Tech

content+a16zpodcast@a16z.com (David George, Andrew Bosworth) — Thu, 24 Apr 2025 10:00:00 +0000

For the past 20 years, consumer technology has been shaped by the same form factors: apps and touchscreens on smartphones. But advances in AI, wearables, and hardware could introduce an entirely new stack—creating a more agentic, adaptive, and immersive computing experience for users everywhere.

Drawing on his early days building Facebook’s News Feed to his work today on smart glasses and AR headsets, Meta CTO Andrew Bosworth joins a16z Growth General Partner David George to share how he's translated emerging technologies into products people use and love. He also explores how breakthroughs in AI and hardware could turn the existing app model on its head, introduce entirely new competitive dynamics and business models for startups, and usher in a post-mobile phone era. If we get it right, Bosworth says, the next wave of consumer tech won’t run on taps and swipes—it’ll run on intent.

Read more, including a full transcript, here: a16z.com/after-mobile-consumer-tech-andrew-bosworth

[00:00:00] The future of content consumption
[00:02:18] Building great products on the backs of tech trends
[00:08:24] The evolution of Reality Labs and imagining a post-mobile world
[00:11:36] Building a bridge to the post-mobile era
[00:15:00] Does AI turn the app model on its head?
[00:21:28] Competing on performance and price in the AI era
[00:24:27] Open source, Llama, and commoditizing your complements
[00:27:49] Risks to the post-mobile vision
[00:32:41] Committing to the vision

In our conversation series AI Revolution, we ask industry leaders how they’re harnessing the power of generative AI and steering their companies through the next platform shift. Find more content from our AI Revolution series on www.a16z.com/AIRevolution

Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment, digital asset, or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

Who Will Own the Internet? a16z’s Chris Dixon on AI and Crypto

content+a16zpodcast@a16z.com (david george, chris dixon) — Fri, 21 Feb 2025 16:00:00 +0000

Technology doesn’t grow in isolation—it evolves in waves. Just as mobile, cloud, and social shaped the internet of the past 20 years, so too could crypto, AI, and new hardware usher in an era of the internet that’s pro-innovation, pro-startup, and pro-creator.

Speaking with a16z Growth General Partner David George, a16z crypto Founder and Managing Partner Chris Dixon breaks down his vision for a new internet, from using crypto to decentralize AI infrastructure and kickstart network effects, to why AI will be this era’s native form of media just as film was in the 1930s. He also explores why the internet’s original covenant—where content creators traded free access for search traffic—is breaking today, and how a better internet could introduce entirely new business models for creators.

Right now, we have a choice to make: will the next era of the internet be shaped by a handful of centralized players, or transformed into an open ecosystem where power and control flow to creators across the globe?

Read more, including a full transcript, here: https://a16z.com/ai-crypto-internet-chris-dixon/

[00:00:30] How technology evolves

[00:02:54] How crypto and AI interact

[00:08:39] Breaking the economic pact of the internet

[00:12:57] From mobile, social, and cloud to crypto, AI, and hardware

[00:14:49] Using crypto to bootstrap network effects

[00:16:33] Is AI frosting or sugar?

[00:19:57] Come for the tool, stay for the network

[00:20:39] Skeuomorphic vs. native technologies

[00:26:07] AI as the creative substrate of our era

[00:30:11] Balancing supply and demand in AI

[00:35:03] What decides consumer adoption of AI?

[00:36:05] What is the ideal future state of the internet?

Chris Dixon’s book is now available in paperback at readwriteown.com.

How AI Is Changing Warfare, with Anduril CEO Brian Schimpf

content+a16zpodcast@a16z.com (David George, Brian Schimpf) — Thu, 13 Feb 2025 17:15:00 +0000

Anduril reimagined how startups can build software and hardware for the defense sector. Now, they're using AI to reimagine modern warfare.

Speaking with a16z Growth General Partner David George, Anduril cofounder and CEO Brian Schimpf discusses how AI helps humans make better strategic decisions by sorting through the enormous amount of data collected from modern battlefields. Brian also discusses navigating the US government’s complex procurement processes, using commercial technologies to kickstart their own product development, and the growing opportunities for startups in defense. Throughout, Brian offers a deep dive into the intersection of technology, geopolitics, and the future of defense.

[00:00:19] Anduril and the rise of defense tech
[00:03:27] The state of AI in warfare
[00:06:02] The role of AI in decisionmaking
[00:09:36] The deterrence value of AI
[00:11:05] How automated can warfare become?
[00:14:51] How to sell to the Department of Defense
[00:18:25] Improving the procurement process
[00:21:23] The urgency for improving R&D cycles
[00:25:16] Driving down costs and speeding innovation
[00:30:26] Project Warp Speed for defense
[00:31:30] The perception and reality of defense startups

Read more, including a full transcript, here: https://a16z.com/how-ai-is-changing-w...

Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

In The Vault: How AI is Powering Payments with Greg Ulrich

content+a16zpodcast@a16z.com (Greg Ulrich, Marc Andrusko) — Tue, 4 Feb 2025 16:00:00 +0000

How does a company as massive as Mastercard decide where to deploy AI? Instead of centralizing every AI initiative, Mastercard operates under a “hub and spoke” model — balancing centralized AI leadership with decentralized innovation across business units.

In this episode, a16z Partner Marc Andrusko chats with Mastercard’s Chief AI and Data Officer Greg Ulrich about Mastercard’s long history of using AI, the opportunities (and potential risks) associated with integrating generative AI into fraud detection, determining what tech to employ based on use cases, and the best advice he’s ever gotten.

“In the Vault” is a podcast series by the a16z Fintech team, where we sit down with the most influential figures in financial services to explore key trends impacting the industry and the innovations that will shape our future.

Resources:

Find "In The Vault" on a16z.com: https://a16z.com/podcasts/in-the-vault/

Find more about a16z's vision for the future of fintech: https://a16z.com/banking-on-ai/

Find Marc Andrusko on X: https://x.com/mandrusko1

Find Greg Ulrich on LinkedIn: https://www.linkedin.com/in/gregu/

Find a16z on X: https://x.com/a16z

Find a16z on LinkedIn: https://www.linkedin.com/company/a16z

Subscribe to the a16z Fintech newsletter: https://info.a16z.com/newsletters-fintech.html

How Jack Henry is Modernizing Banking Infrastructure

content+a16zpodcast@a16z.com (Ben Metz, Angela Strange) — Thu, 19 Dec 2024 14:30:57 +0000

Most financial institutions still bank on software built before the internet, but Jack Henry's CTO, Ben Metz, is leading a quiet revolution to change that. Speaking with a16z General Partner Angela Strange, Metz shares how banks’ historical tech infrastructure and regulatory obstacles have stymied innovation—and how Jack Henry is helping them overcome these challenges. Metz outlines actionable ways startup founders can help smaller community banks leverage artificial intelligence and cloud computing, reshaping the industry at large.

Chapter Breakdown:

0:47 Backstory
2:15 Community banks and historical infrastructure
4:30 Pre-internet banking & software realities
6:45 Challenges of scaling historical banking tech
8:30 Building software & COBOL
12:15 Dissecting core banking systems
15:40 How regulatory hurdles impact innovation
18:30 Mobile banking and market shiftsT
22:45 Integrating AI into banking's foundation
25:30 Digital service core to banking
28:15 Where AI will be integrated first
31:20 Advice for fintech founders
34:45 Building a data platform to enable innovation
38:20 Working together: banking & tech startups

Building a $20B+ Open Source Business with MongoDB's Eliot Horowitz

content+a16zpodcast@a16z.com (Seema Amble, Eliot Horowitz) — Thu, 12 Dec 2024 15:08:32 +0000

a16z Partner Seema Amble talks with MongoDB and Viam co-founder Eliot Horowitz about building sustainable open source software tools. From challenging Oracle to building the de facto cloud-based database management tool, Horowitz outlines MongoDB’s early go-to-market strategies, approach to community building, and enterprise sales motion. This episode provides detailed tips on creating solutions for the developer community, building trust amongst enterprises, and successfully scaling a business supported by the open source community.

01:18-03:42 Why open source is a strategic business decision

3:42:6:03 Product development strategy + making developers’ lives easier

6:03-08:24 MongoDB strategy of building community through meetups

08:24-10:49 The five-second rule for developer products

10:49-13:09 How MongoDB used meetups to fuel growth

13:09-15:35 The importance of getting people excited about your product

15:35-19:29 MongoDB’s enterprise sales strategy

19:28-20:26 MongoDB’s recruiting strategy

20:26-25:12 Open source customers vs. users, adoption patterns

25:12-27:35 The evolution of enterprise deals and building trust through demos

27:35-32:23 Product communication strategies and tactics

32:23-39:37 Managing customers and building long-term relationships

39:37-40:16 Outro

How Zapier Became Profitable in 3 years and Scaled to $5B with Wade Foster

content+a16zpodcast@a16z.com (Seema Amble, Wade Foster) — Tue, 10 Dec 2024 13:56:40 +0000

a16z Partner Seema Amble connects with Zapier co-founder Wade Foster about the company’s founding and GTM success utilizing a product-led growth (PLG) strategy. Chock-full of actionable insights, this episode explores Zapier’s product strategy, customer experience, and how the team built a sustainable growth engine that enabled them to reach profitability within three years. Foster also provides valuable guidance on brand strategy and how creating an unconventional “weird” brand helped Zapier differentiate from competitors.

1:15-2:05 Zapier's origin story
2:05-3:13 Initial product idea
3:13-5:06 Finding product-market fit and YC
5:06-7:43 How Zapier found their early customers
7:43-10:15 Strategic approach to identifying services to integrate
10:15-13:28 Identifying customer needs and optimizing onboarding
13:28-16:10 Developing a scalable customer acquisition strategy
16:10-19:07 Guidance on building a successful self-serve product
19:07:23:52 Early pricing experiments and brand evolution
23:53-27:04 Early hiring strategy
27:04-29:59 Reflecting on Zapier’s brand identity and product strategy
29:59-31:19 Advice for founders regarding customer acquisition and GTM
31:19-31:59 Outro

Please note that the content here is for informational purposes only; should not be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see

a16z.com/disclosures

How Gusto Used Customer Input to Scale Growth with Tomer London

content+a16zpodcast@a16z.com (Seema Amble, Tomer London) — Thu, 5 Dec 2024 16:22:46 +0000

In this episode, a16z Partner Seema Amble chats with Tomer London, co-founder of Gusto, about establishing product-market fit and product discovery. London shares how Gusto, now valued at ~$10 billion with 300,000+ customers, identified early customers who could provide valuable feedback that helped the team optimize the self-service product experience. The conversation explores Gusto's approach to product development, as well as managing and incorporating customer feedback while maintaining a clear product vision.

1:18-3:14 Gusto’s founding story
3:14- 4:56 Solidifying a GTM sales strategy
4:56-10:03 Identifying early customers and perfecting the sales pitch
10:03-12:45 Working with customers to optimize the product UX
12:45-14:31 Engendering trust and finding success with accountants
14:31-16:41 The role accountants planned in Gusto’s success
16:41-19:34 Creating a feedback funnel and balancing product vision
19:34-22:38 Self-service strategy and measuring success
22:38- 23:45 Refining the UX at scale
23:45-25:45 Identifying real-world use cases to inform product strategy
25:45-29:52 GTM learnings and advice
29:52-30:05 Outro

How to Build a Thriving AI Ecosystem with Lisa Su, CEO of AMD

content+a16zpodcast@a16z.com (a16z) — Wed, 30 Oct 2024 18:43:09 +0000

High-performance compute is the bedrock of generative AI, and if there’s anyone who knows about high-performance chips, it’s AMD CEO Lisa Su. In this wide-ranging conversation with a16z Operating Partner Bob Swan—himself formerly CEO of Intel—Lisa lays out her vision for the evolution of compute within the AI ecosystem, touching not only on raw power and the continuation of Moore’s Law, but also how AMD will support “the right compute for each form factor” for a wider ranges of real-world gen AI use cases. Lisa also shares her perspective on the state of chip manufacturing, how AMD matches their R&D cycles to fast-moving industries, and how partnerships build strong ecosystems.

Read more, including a full transcript, here: https://a16z.com/how-to-build-ai-ecos...

Time stamps:

[00:01:37] Lisa's career in compute
[00:04:48] Compute in the genAI era
[00:09:39] High performance or multimodal?
[00:10:47] Making the genAI ecosystem open
[00:14:16] The chip supply chain
[00:17:53] Resiliency and the CHIPS Act
[00:20:54] How AMD balances long development cycles with short term innovation
[00:24:48] Learnings from the hyperscaler market
[00:26:54] What being fabless means for AMD
[00:31:24] Lisa's advice for startup founders

Find more content from our AI Revolution series on www.a16z.com/AIRevolution.

a16z Growth's David George on His Frameworks for Late-Stage Investing

content+a16zpodcast@a16z.com (Tyler Hogge, Sterling Snow, David George) — Tue, 15 Oct 2024 13:00:00 +0000

Finding and backing companies that can reach escape velocity is the name of the game over here at a16z Growth—but picking those winners is far from easy. David George, head of the a16z Growth fund, sat down with the I/O podcast to discuss his mental models for growth-stage investing, what it really takes to go public, where AI is today and where it’s headed, and more.

[00:03:19] What makes Andreessen Horowitz different

[00:08:29] David's mental model for investing

[00:18:23] Focusing on inputs, not outputs

[00:26:52] What constitutes a growth company?

[00:29:14] David's three investing frameworks

[00:36:45] How to measure the ROI of R&D

[00:42:15] What it takes to go public today

[00:46:43] AI: market structure and infrastructure vs. application layers

To read a transcript of this conversation, click here.

Why Human Data is Key to AI: Alexandr Wang from Scale AI

content+a16zpodcast@a16z.com (Alexandr Wang, David George) — Fri, 4 Oct 2024 17:23:55 +0000

In this conversation with a16z general partner David George, Scale AI founder and CEO Alexandr Wang discusses the three pillars of AI—models, compute, and data—and how creating abundant data is core to the evolution of gen AI. With Scale’s work across enterprise, automotive, and the public sector, Alex is also building the critical infrastructure that will allow any organization to use their proprietary data to build bespoke gen AI applications. In addition to talking about frontier data, Alex also shares his learnings from the growth of Scale, his approach to leadership, and what he thinks growth-stage founder/CEOs tend to get wrong about hiring.

Read more, including a full transcript, here: https://a16z.com/frontier-data-foundries-alex-wang-scale-ai/

Timestamps:

[00:00:58] How frontier data will change gen AI

[00:08:47] Are big tech companies over-investing in AI?

[00:14:39] Where the best AI businesses will thrive

[00:17:05] How enterprise businesses are approaching AI adoption

[00:19:50] What does the next phase of gen AI products look like?

[00:23:23] Alex's approach to scaling Scale

[00:25:36] The founder fallacy

[00:30:12] MEI and how Alex views talent acquisition

In the Vault: Assessing AI Impact vs. Hype with John Stecher of Blackstone

content+a16zpodcast@a16z.com (John Stretcher, David Haber) — Wed, 25 Sep 2024 15:00:00 +0000

a16z general partner David Haber talks to John Stecher, Chief Technology Officer at Blackstone, where he advances cutting-edge technology, heads up innovation investing, and advises the firm’s investment teams and portfolio companies. The conversation covers how he decides whether to build tech in-house or partner with startups, what qualities he’s looking for in early stage companies, and how he sees AI impacting real estate, credit, energy, and ecommerce.

0:00-1:05 Intro

1:06-3:55 Changes in finance x tech over the past 2 decades

3:56-5:06 Investing in "themes" across asset classes

5:07-7:00 What the CTO role entails

7:01-9:00 "Build it" vs. "buy it": trade-offs

9:01-11:57 Advice for early stage companies

11:58-16:37 Ways Blackstone is incorporating generative AI

16:38-17:46 How AI changes the role of an analyst

17:47-21:04 Gen AI's impact on private equity, real estate, credit, more

21:05-22:54 How Blackstone will evolve over the next five years

22:55-23:26 Outro

In the Vault: AI and Banking Innovation with Tim Karpoff of Citi

content+a16zpodcast@a16z.com (Tim Karpoff, David Haber, Marc Andrusko) — Tue, 20 Aug 2024 15:00:00 +0000

a16z general partner David Haber and fintech partner Marc Andrusko talk to Tim Karpoff, the Global Head of Strategy at Citi, where he guides the bank’s core focus areas, as well as future investment in emerging tech like AI. The conversation covers the shifting landscape of banking policy and regulation, the increasingly important role startups are playing in partnership with big banks, and where Tim disagrees with the zeitgeist when it comes to the adoption of AI in financial services.

0:00-1:05 Intro

1:06-2:28 Navigating bureaucracy

2:29-4:26 What "chief strategy officer" entails

4:27-8:18 Citi's role in the banking ecosystem

8:19-9:16 Fallout from the 2023 banking crisis

9:17-13:10 Citi's revised risk controls and tech investment

13:11-14:59 How Citi works with startups

15:00-20:00 Citi's future: AI and regulation

20:01-23:33 What people get wrong when it comes to AI

23:33-24:12 Outro

Building the World’s Most Trusted Driver with Waymo's Dmitri Dolgov

content+a16zpodcast@a16z.com (Dmitri Dolgov, David George) — Tue, 13 Aug 2024 14:00:00 +0000

Waymo co-CEO Dmitri Dolgov joined a16z general partner David George to discuss how Waymo is using genAI to help them build safer, sustainable, and more accessible transportation. In the conversation, Dmitri talks about the potential of embodied AI, the value of simulations and building training data, and his approach to leading a company focused on solving the challenges of building AI that can navigate the real world.

[00:01:22] The early days of autonomous vehicles
[00:05:27] Layering genAI into traditional AI/ML
[00:09:42] The value of simulation
[00:15:56] The hard part about integrating AI in autonomous systems
[00:22:45] AI in the real world
[00:28:47] Where does Waymo go from here?
[00:37:21] Dmitri's learnings from hard problems

This conversation is part of our AI Revolution series, which features some of the most impactful builders in the field of AI discussing and debating where we are, where we’re going, and the big open questions in AI. Find more content from our AI Revolution series on www.a16z.com/AIRevolution.

Bringing Production-Ready GenAI to the Enterprise

content+a16zpodcast@a16z.com (a16z) — Wed, 7 Aug 2024 14:00:00 +0000

As genAI expands through the enterprise, many leaders are figuring out how to evolve their genAI prototypes into production-ready tools. Pinecone CEO Edo Liberty and LangChain CEO Harrison Chase discuss which parts of the stack to build or buy, how to improve out-of-the-box models by helping customers select and ingest the right data, and picking the right partners to scale genAI applications with a16z Growth General Partner Sarah Wang.

[00:02:16] Navigating the gap from prototype to production
[00:07:03] How to educate partners on genAI tools and capabilities
[00:11:38] Deciding whether to build or buy
[00:17:36] Successful implementations of genAI
[00:21:20] Balancing enterprise and open-source community needs
[00:23:06] Balancing short-term revenue gains with long-term vision
[00:25:18] Picking the right partners to scale

For a transcript of this episode of a16z Live!, click here.

In the Vault: Public Market and Macro Perspectives with Mark Casey of Capital Group

content+a16zpodcast@a16z.com (Mark Casey, David George) — Tue, 23 Jul 2024 15:00:00 +0000

In this episode, which took place at a16z's Connect Fintech event, a16z General Partner David George interviews Capital Group's Mark Casey on his investment philosophy, what sends him into what he calls "barnacle mode," his preference for customer-focused North Star metrics, and more.

0:00-1:42 Intro

1:42-5:58 Approach to investing

5:58-8:20 What Casey told Jeff Bezos, and what he learned

8:20-12:57 How CEOs communicate with public market investors; unconventional North Star metrics

12:57-15:48: Why Casey loves dividends

15:48-20:44 Macro trends and investing theses

20:44-21:37 Ecommerce predictions

21:37-23:15 Opportunities and choke points in AI

23:15-25:18 What makes a great public company?

25:18-26:04 Outro

In the Vault: New Applications in Fintech with Plaid’s Zach Perret and Marqeta’s Simon Khalaf

content+a16zpodcast@a16z.com (Angela Strange, Simon Khalaf, Zach Perret) — Thu, 20 Jun 2024 15:00:00 +0000

In this conversation, which took place at a16z's Connect Fintech event, a16z General Partner Angela Strange, Plaid CEO and cofounder Zach Perret, and Marqeta CEO Simon Khalaf discuss how AI will shape the future of banking, the battle between payment rails in the U. S., and how there's still opportunity to transform the basic credit card into a fully digital product.

0:00-1:42 Intro

1:42-1:56 Topics: Generative AI, payment rails shift, and regulation in open banking and sponsor banking

1:56-4:46 GenAI's potential impact on credit modeling and fraud

4:46-7:09 Implications of payment products becoming digital products ("The open face of the internet")

7:09-8:33 Why brands need to embed finance, and why every company will eventually be a fintech company

8:33-11:01 The card vs. pay-by-bank debate

11:01-12:24 New infrastructure to combat fraud

12:24-17:27 Reassessing traditional "top-of-wallet" tactics and longstanding business models

17:27-20:04 Potential implications of Visa/Mastercard antitrust suit

20:04-24:12 Regulation around open banking and sponsor banks

24:12-24:40 Outro

In the Vault: Placing Multiple Bets on a ‘Mosaic of Solutions’ With Former Global Payments CEO Jeff Sloan

content+a16zpodcast@a16z.com (Angela Strange) — Tue, 30 Apr 2024 13:00:00 +0000

In a new episode of In the Vault, a16z General Partner Angela Strange talks with Jeff Sloan, former CEO of Global Payments, about how he was early to spot significant industry trends, how to make bets that move an organization, and the sea change that AI represents for the financial services industry.

0-1:40 Intro

1:40-8:15 Joining Global Payments

8:15-19:30 Placing many bets

19:30-26:10 Deal integration and scale advantage

26:10-31:35 GenAI sea change

31:35-32:19 Outro

In the Vault: Turning Developers Into Clients With Marco Argenti From Goldman Sachs

content+a16zpodcast@a16z.com (David Haber) — Tue, 30 Apr 2024 13:00:00 +0000

In a new episode of In the Vault, a16z General Partner David Haber talks with Marco Argenti, the chief information officer at Goldman Sachs, about bringing fintech processes into financial services, turning developers into clients, and how AI is a major inflection point in the history of technology.

0-1:30 Intro

1:30-12:05 From tech to financial services

12:05-17:30 Turning developers into clients

17:30-23:50 GenAI and productivity

23:50-28:50 The future of financial services

28:50-29:31 Outro

In the Vault: Finding a Single Source of AI Truth With Marty Chavez From Sixth Street

content+a16zpodcast@a16z.com (David Haber) — Tue, 30 Apr 2024 13:00:00 +0000

In a new episode of In the Vault, a16z General Partner David Haber talks with Marty Chavez, a partner and vice chairman of Sixth Street Partners, about the foundational role he’s had in merging technology and finance throughout his career, and the magical promises and regulatory pitfalls of AI.

0-1:30 Intro

1:30-12:50 Marty's history and transition to Wall Street

12:50-20:50 Financial Crisis and SecDB

20:50-32:10 GenAI's impact

32:10-36:15 AI and biotech

36:15-37:06 Outro

Harnessing Ecosystem-Led Growth with Crossbeam's Bob Moore

content+a16zpodcast@a16z.com (a16z) — Tue, 9 Apr 2024 15:00:00 +0000

In this SaaS era, partnering with no one means competing with everyone. How the best companies take advantage of ecosystem-led growth—or where they sit in the SaaS ecosystem to improve acquisition, expansion, and access to new markets, as discussed by a16z general partner Sarah Wang and Crossbeam CEO Bob Moore.

[00:01:43] The birth of ecosystem-led growth
[00:05:12] The data revolution in partnerships
[00:12:46] Integrating ecosystem-level GTM motions
[00:16:29] Bob's founder history
[00:24:30] Ecosystem-qualified leads and new opportunities
[00:29:34] ELG as AI force multiplier

For a transcript of this episode of a16z Live!, click here.

AI Revolution: Bringing AI to the Masses with Quora's Adam D'Angelo

content+a16zpodcast@a16z.com (David George, Adam D'Angelo) — Wed, 20 Mar 2024 15:00:00 +0000

CEO of Quora Adam D’Angelo discusses how building infrastructure for creators can democratize AI, in conversation with a16z’s David George.

[01:07] Social networks as compliment to AI
[03:59] Poe: bringing AI to the masses
[05:51] The future of AI is multi-model and multimodal
[08:11] Is the model the product?
[11:31] Building AI infrastructure for creators
[13:41] Navigating platform shifts
[16:02] Sharing human- and computer-generated knowledge
[17:43] Knowledge sharing on the internet
[20:41] The benefits of scale for AI
[21:59] Competing on scale or feature differentiation
[25:01] Fault tolerance as a wedge for startups

Recruiting and Retaining the Right Executive Talent

content+a16zpodcast@a16z.com (Matt Oberhardt, Nolan Church, Kelly Dragovich) — Mon, 12 Feb 2024 15:30:41 +0000

Hiring the right executives at the right time is the key to scaling your company. But to many founders, the executive search and hiring process can feel like a black box. a16z talent partner Matt Oberhardt dives deep into the executive search process with Kelli Dragovich and Nolan Church on the HR Heretics podcast.

[00:01:21] How a16z talent partners assess talent

[00:03:42] Balancing internal and external roles

[00:04:57] Measuring success in talent assessment

[00:06:07] The MOC

[00:10:29] Whiteboard sessions for assessing fit

[00:13:10] Referencing as a continuous cycle

[00:16:47] Putting negative references in context

[00:20:25] Assessing personal growth vs. mistakes

[00:21:50] Establishing trust with founders

[00:25:03] Vetting EQ

[00:26:53] Measuring success of what you can't control

[00:28:43] Why hire veterans for startups

[00:33:45] Talent landscape in 2024

[00:35:20] Recruiting top talent in a tight market

[00:38:42] Hiring the "operational glue"

[00:39:36] The value of tough feedback

You can read the key takeaways from this conversation, along with a transcript, here.

Building Better Communities with Flock Safety

content+a16zpodcast@a16z.com (David Ulevitch, Garrett Langley, Kevin McMahill) — Wed, 17 Jan 2024 17:00:00 +0000

Respecting privacy and building trust with communities is essential to effectively integrate technology into public safety. a16z general partner David Ulevitch, Flock Safety’s Garrett Langley, and Las Vegas Metropolitan Police Department Sheriff Kevin McMahill discuss how to build and implement products that communities can trust.

[00:01:22] Flock Safety's impact on public safety

[00:05:50] Building trust through tech

[00:08:23] How Flock Safety builds its product roadmap

[00:11:06] Drones as first responders

[00:15:46] Data privacy and protection

[00:19:05] How the Las Vegas Metropolitan Police Department rolls out new technology

[00:21:11] AI, robots, and the future of tech in public safety

This conversation was recorded at a16z’s 2023 LP Summit. To read a transcript of this talk, click here.

My First 16: Launching a New Category with Modern Treasury's Dimitri Dadiomov

content+a16zpodcast@a16z.com (Seema Amble) — Tue, 12 Dec 2023 17:00:00 +0000

In this episode, a16z partner Seema Amble talks with Dimitri Dadiomov, the co-founder and CEO of payment operations platform Modern Treasury, about the challenges of creating a new category, hiring for marketing before you hire for sales, and why developing new features is similar to birding.

0:00 - 1:20 Intro

1:20 - 8:55 The founding of Modern Treasury

8:55 - 15:28 First customers

15:28 - 20:07 Building trust

20:07 - 32:00 Creating a category

32:00 - 35:28 Advice for founders/Outro

My First 16: Creating a Supportive Builder Community with Plaid's Zach Perret

content+a16zpodcast@a16z.com (Seema Amble) — Tue, 5 Dec 2023 17:00:00 +0000

In this episode, a16z partner Seema Amble talks with Zach Perret, the co-founder and CEO of Plaid, about how Plaid built a community in the early days to acquire customers, how they tracked “free radicals,” and how to orient your first customers around speed.

0 - 1:09 Intro

1:09 - 9:57 Plaid history

9:57 - 16:39 First customers

16:39 - 26:45 Pricing philosophy

26:45 - 29:27 Boring as a brand

29:27 - 33:01 Advice for founders/Outro

My First 16: Welding Yourself to Early Customers with Marqeta's Jason Gardner

content+a16zpodcast@a16z.com (Seema Amble) — Tue, 28 Nov 2023 17:00:00 +0000

In this episode, a16z partner Seema Amble talks with the founder and current executive chairman of Marqeta Jason Gardner about what it means to be welded to your customer and how to expand in multiple verticals.

0:00-1:10 Intro

1:10-6:01 Marqeta's beginning

6:01-9:15 First customers

9:15-16:25 "Magic" product market fit

16:25-24:58 Building customer relationships/Pricing

24:58-32:18 Advice for founders

My First 16: Doubling Down on Founder-Led Sales with Pilot's Waseem Daher

content+a16zpodcast@a16z.com (Seema Amble) — Tue, 21 Nov 2023 17:00:00 +0000

In a new episode of My First 16, a16z partner Seema Amble talks with co-founder and CEO of Pilot Waseem Daher on how he thought about the importance of charging, how secondary signals often matter in an area like accounting, and never stepping away from doing founder-led sales.

0:00 - 1:45 Intro

1:45 - 6:36 Pilot's beginning

6:36 - 13:25 First customers

13:25 - 18:02 Pricing

18:02 - 25:29 Building a GTM team

25:29 - 27:58 Advice for founders/Outro

Sales–Product Tension, the Secret to Segment’s Success

content+a16zpodcast@a16z.com (Joe Morrissey, Tido Carriero) — Fri, 17 Nov 2023 15:00:00 +0000

Sales wants more features. Product gets bogged down with one-off requests. Progress and growth grinds to a halt. It's a familiar story. How Segment turned the sales-product tension into a successful $3.2B acquisition, as told by the former CRO Joe Morrissey and former chief product development officer Tido Carriero.

[00:01:29] Joe's start as CRO

[00:03:40] The low point: annual planning

[00:07:59] Building a more focused product roadmap

[00:10:57] Why GTM feedback is essential to building great product

[00:13:04] Identifying value drivers in 48 hours

[00:19:11] How technical should sales be?

[00:20:44] How annual planning changed day-to-day operations

[00:22:57] Segment's Lighthouse program

[00:24:54] Reorging to deliver on new product priorities

[00:27:14] How engineering helped develop the product roadmap

[00:29:18] Leading a platform initiative

This conversation was recorded at ELC 2023. To read a transcript of this conversation, click here. For more about value-based selling and moving upmarket, check out Getting Ready to Move Upmarket and The Key to Selling in a Downturn.

My First 16: Competing in a Crowd of Incumbents with Mercury's Immad Akhund

content+a16zpodcast@a16z.com (Seema Amble) — Tue, 14 Nov 2023 17:00:00 +0000

In a new episode of My First 16, a16z partner Seema Amble talks with co-founder and CEO of Mercury Immad Akhund about the idea of a “minimum delightful product” in fintech, doing the spreadsheet math on unit economics early on, and how to compete in a category already filled with incumbents.

0:00 - 1:28 Introduction

1:28 - 9:14 History of Mercury

9:14 - 19:07 Mercury's first customers

19:07 - 22:15 Scaling up

22:15 - 25:48 Pricing journey

25:48 - 31:37 Lessons and advice

AI Revolution: Universally Accessible Intelligence with Character.ai's Noam Shazeer

content+a16zpodcast@a16z.com (Noam Shazeer, Sarah Wang) — Wed, 27 Sep 2023 01:00:00 +0000

Noam Shazeer, Character.ai CEO and cofounder, talks to a16z's Sarah Wang about the dawn of universally accessible intelligence, the compute it will take to power it, and his pursuit of AGI's first use...

[0:59] Real Noam vs. AI Noam
[6:14] Next unlocks
[8:11] First use case for AGI
[11:06] Building a full-stack LLM
[13:33] Noam calculates global compute capacity
[15:24] Universally accessible intelligence

This conversation is part of our AI Revolution series, recorded August 2023 at a live event in San Francisco. The series features some of the most impactful builders in the field of AI discussing and debating where we are, where we’re going, and the big open questions in AI. Find more content from our AI Revolution series on www.a16z.com/AIRevolution.

AI Revolution: Food Fights in the Enterprise with Databricks' Ali Ghodsi

content+a16zpodcast@a16z.com (Ali Ghodsi, Ben Horowitz) — Wed, 27 Sep 2023 01:00:00 +0000

Ali Ghodsi, CEO and cofounder of Databricks, and Ben Horowitz, cofounder of a16z, explain the data wars happening inside and outside enterprises and how they could impact the evolution of LLMs.

[0:59] Why is it so hard for enterprises to adopt AI?
[3:29] Data wars
[4:49] Big vs. small LLMs
[8:35] Finetuning
[14:14] Open source AI
[18:13] Benchmarks
[19:51] Why Ali isn't afraid of AI

AI Revolution: Digital Biology with insitro's Daphne Koller

content+a16zpodcast@a16z.com (Daphne Koller, Vijay Pande) — Wed, 27 Sep 2023 01:00:00 +0000

Daphne Koller is the founder and CEO of insitro, a company using AI and machine learning to engineer drug discovery. In this conversation with a16z's Vijay Pande, she discusses how an LLM for cells could revolutionize drug discovery and how to bridge the technological and cultural divide between building with atoms and building with bits.

[0:59] Why life sciences?
[3:42] AI in the life sciences
[7:20] LLM for cells
[11:55] Engineering disease and drug discovery
[13:51] Bits vs. atoms
[17:55] The opportunity ahead

AI Revolution: Democratizing Design with Figma's Dylan Field

content+a16zpodcast@a16z.com (Dylan Field, David George) — Wed, 27 Sep 2023 01:00:00 +0000

Will AI take all the design jobs? Dylan Field, founder and CEO of Figma, looks at the relationship between designers, developers, and AI, in conversation with a16z's David George.

[0:58] Will AI replace designers?
[4:13] Human vs. AI creativity
[8:38] Applying AI to design
[11:35] Startups vs. incumbents

AI Revolution: Leveling Up with Roblox's David Baszucki

content+a16zpodcast@a16z.com (David Baszucki, Jonathan Lai) — Wed, 27 Sep 2023 01:00:00 +0000

Roblox cofounder and CEO David Baszucki and a16z's Jonathan Lai discuss the ways AI is changing games and virtual worlds, as well as how we create them.

[1:00] Generative AI in games
[4:56] Fully personalized playthroughs
[7:50] Roblox's generative model
[11:28] Future of interfaces
[13:25] impact on creators
[16:36] NPCs as copilots
[18:49] VR & spatial computing

AI Revolution: Where We Go From Here with OpenAI's Mira Murati

content+a16zpodcast@a16z.com (Mira Murati, Martin Casado) — Wed, 27 Sep 2023 01:00:00 +0000

As CTO of OpenAI, Mira Murati oversaw the development and release of GPT-4 and ChatGPT. Here she tells Martin Casado the story behind the release of ChatGPT—and what it tells us about the future of AI and human-machine interactions.

[0:59] Mira's background
[4:55] Math, physics, and AI
[7:31] Natural language interfaces
[10:51] OpenAI Roadmap
[17:47] Scaling Laws
[20:48] One model to rule them all?
[23:34] The next 5-10 years

AI Revolution: Improving AI with Anthropic's Dario Amodei

content+a16zpodcast@a16z.com (Dario Amodei, Anjney Midha) — Wed, 27 Sep 2023 01:00:00 +0000

Cofounder and CEO of Anthropic Dario Amodei unpacks how far can scaling laws take us and how can AI be used to improve AI, in conversation with a16z's Anjney Midha.

[0:59] Dario's background
[2:45] GPT-2's emergent capabilities
[5:16] Scaling laws
[8:55] Why are there so many physicists in AI?
[11:58] Constitutional AI
[18:29] Anthropic's Roadmap

AI Revolution: Copilots and the Future of Knowledge Work with Microsoft's Kevin Scott

content+a16zpodcast@a16z.com (Kevin Scott, Bob Swan) — Wed, 27 Sep 2023 01:00:00 +0000

Microsoft CTO Kevin Scott, in conversation with a16z's Bob Swan, explains how AI copilots are keeping developers longer in a flow state and why AI copilots more broadly could be the start of an industrial revolution for knowledge work.

[0:59] Microsoft's approach to AI
[6:15] The next Industrial Revolution
[10:47] Developer productivity & flow state
[15:46] Reprogramming the American Dream
[20:08] Advice to builders

LATW 2022: Art of the Deal

content+a16zpodcast@a16z.com (Marc Andreessen, Sriram Krishnan, Ari Emanuel) — Thu, 27 Oct 2022 19:30:00 +0000

a16z Cofounder and General Partner Marc Andreessen and Endeavor CEO Ari Emanuel are interviewed by a16z General Partner Sriram Krishnan at the “Time to Build: LA” event during LA Week. The trio chat about the future of content distribution, the bull case for VR over AR, the end of corporate brands, and why there is (or isn’t) ever anything good to watch on TV.

LATW 2022: Building the Future of Games

content+a16zpodcast@a16z.com (Jon Lai, David Banks, Timmu Tõke) — Mon, 24 Oct 2022 18:00:00 +0000

In this episode of a16z Live, David Banks, a former Riot Games executive who's now the co-founder and CEO of Elodie Games, and Timmu Tõke, the co-founder and CEO of Ready Player Me, a leading platform for cross game avatars, join a16z General Partner and games investor Jon Lai for a conversation about where they think the metaverse is going, and the future of building games

LATW 2022: Building Better Factories

content+a16zpodcast@a16z.com (Chris Power, Oliver Hsu) — Mon, 24 Oct 2022 16:00:00 +0000

In this episode of a16z Live, Chris Power, the Founder and CEO of the precision parts manufacturing company, Hadrian, talks with a16z American Dynamism Partner Oliver Hsu, about why he decided to build his factories in LA, why software engineers shouldn't be afraid of manufacturing company jobs, and how a single mom and pop machinist shop can affect the national supply chain. What follows is a slightly edited version of that conversation.

LATW 2022: Building Better Marketplaces

content+a16zpodcast@a16z.com (Connie Chan, Grant LaFontaine) — Mon, 24 Oct 2022 16:00:00 +0000

In this episode of a16z Live, Grant LaFontaine, the co-founder and CEO of the livestream shopping platform Whatnot, talks with a16z General Partner Connie Chan about building the company, his experience as the site's first person to go live, and why he prefers Los Angeles over San Francisco. What follows is a slightly edited version of that conversation.

Investing in Los Angeles

Mon, 24 Oct 2022 15:00:00 +0000

To celebrate the L.A. community and the city's growth, a16z recently hosted, "Time to Build Los Angeles," an event where we invited L.A.-based investors, founders, and operators from across a diverse range of industries to talk about company building in L.A. In the first in our series of interviews, we invited Andrew Chen from a16z, Minnie Ingersoll from TenOneTen, and Turner Novak from Banana Capital to talk about why L.A. is at an inflection point, misperceptions about the region, and what makes a great meme. But first, we opened our panel discussion with a presentation from a16z consumer partner, Katia Ameri, on what you need to know about the L.A. scene and why we think it's worth paying attention to in the years to come. What follows is a slightly edited version of that conversation.

Titan's Clayton Gardner on How the Fintech Market is Changing

content+a16zpodcast@a16z.com (Anish Acharya, Alex Immerman, Clayton Gardner) — Thu, 20 Oct 2022 15:30:00 +0000

In this episode of a16z Live, we are joined by Titan Invest co-founder and co-CEO Clayton Gardner; a16z General Partner Anish Acharya; and a16z growth partner, Alex Immerman. The trio starts their conversation by diving into the difference between active and passive investment management and where Titan fits into that matrix. Building upon that foundation, they discuss how the fintech market is changing, why historically the best fund managers have not taken retail money, and whether that's changing the importance of curation in UX on competitive platforms, and of course the role of regulation.

Ben Horowitz on How the Best Leaders Build Culture

content+a16zpodcast@a16z.com (Ben Horowitz, David Weiden) — Fri, 19 Aug 2022 14:00:00 +0000

Ben Horowitz discusses the leadership styles of Intel’s Andy Grove and Apple’s Bill Campbell, how Okta won its market with culture, and how to look for and hire the talent you don’t have in an interview with David Weiden, founding partner at Khosla Ventures, at the Khosla Ventures CEO Summit. Read a transcript of the conversation here.

0:40: The management legacy of Intel’s Andy Grove
4:26: Why everyone remembers Bill Campbell
7:35: How culture gave Okta the competitive edge
12:15: Finding the talent you don’t have
16:07: Building a resilient company culture

Read a transcript of this conversation here.

The Importance of Partnerships in the Great Unbundling

content+a16zpodcast@a16z.com (Sarah Wang, Bob Moore) — Wed, 29 Jun 2022 19:30:05 +0000

The API economy and a Cambrian explosion of apps are transforming best-in-class tech from monolithic tools to a stack of 20 applications that work together. Amid this unbundling, partnerships have become a critical part of early go-to-market strategy that can lead to higher quality pipeline and accelerated sales. In this fireside chat, recorded at the 2022 Crossbeam Supernode conference, a16z General Partner Sarah Wang and Bob Moore, Cofounder and CEO of Crossbeam, discuss how partnerships have changed and why the best startups invest early in building a partnership program.

You can read a transcript of this podcast here.

Goldman Sachs' Stephanie Cohen on How the Firm's Approach to Technology Has Evolved

content+a16zpodcast@a16z.com (David Haber, Stephanie Cohen) — Thu, 23 Jun 2022 16:51:42 +0000

a16z General Partner David Haber chats with his former colleague Stephanie Cohen, Goldman Sachs' Global Co-Head of Consumer and Wealth Management, about her journey from being an investment banker to running a global division, how Goldman Sachs stays relevant to different client audiences, and how fintech entrepreneurs can think about partnering with the financial services giant.

CISA Deputy Director Nitin Natarajan on What Cybersecurity Threats Keep Him Up At Night

content+a16zpodcast@a16z.com (Joel de la Garza, Nitin Natarajan, Leila Hay) — Fri, 10 Jun 2022 17:54:12 +0000

As the deputy director for the Cybersecurity and Infrastructure Security Agency (CISA), Nitin Natarajan spends most of his days worrying about everything from risk identification and mitigation, to educating young people and small businesses on their potential to be victims. In this fireside chat with Joel de la Garza, a16z operating partner for security, the two men discuss what keeps the CISA official up at night, his view of the situation in Ukraine and Russia, and how being tech savvy doesn’t translate into being cyber savvy (especially for kids).

Building Towards American Dynamism with Chris Power, CEO of Hadrian

Sat, 9 Apr 2022 03:08:43 +0000

Katherine Boyle, General Partner at a16z is joined by Hadrian founder and CEO Chris Power, Packy McCormick, founder of Not Boring, and a16z co-founder Marc Andreessen to discuss the opportunity to automate and upskill in the precision parts industry and shore up U.S. manufacturing with new technology.

Ken Griffin on Unfettered Conversations with A and Z

content+a16zpodcast@a16z.com (Marc Andreessen, Ken Griffin, Alex Rampell) — Fri, 3 Dec 2021 18:08:08 +0000

An excerpt from a Clubhouse conversation, where Marc interviews Ken Griffin, CEO and founder of Citadel, on GameStop one year later and why the stock price hasn't crashed, as well as about his winning bid for the Constitution in the auction against ConstitutionDAO.

a16z Bio + Health #20: How useful is real world data in medicine?

Sun, 14 Nov 2021 22:07:42 +0000

What are you doing with real world data? [1:39]
How valuable is real world data? [7:24]
How and where do we need shared data infrastructure? [16:37]
Can real world data be used for clinical decision support? [20:40]
Are diagnostic companies becoming the data aggregator layer? [26:52]
What will define the core competency of academic medical centers (AMCs)? [30:35]
How could drug manufacturers use real world data? [33:58]

For more on the digital health, visit a16z.com/digital-health-builders. And for more great a16z Bio shows on Clubhouse, follow the a16z bio club.

a16z Bio + Health #19: Going B2C2B in Digital Health

Fri, 29 Oct 2021 18:25:45 +0000

Who is your "B" and who is your "C"? [2:02]
Why did they choose B2C2B? [6:36]
How did they craft their enterprise story? [11:42]
Does going B2C2B increase CAC (customer acquisition costs)? [16:56]
Three things to build an enterprise story around [22:26]
How did their choice of B2C2B impact investor conversations? [34:23]
What mix of consumer vs. healthcare talent did they need? [40:42]

For more on the new digital health go-to-market, visit a16z.com/digital-health-builders. And for more great a16z Bio shows on Clubhouse, follow the a16z bio club.

One on One with A and Z #12: What is the most misunderstood area of markets?

content+a16zpodcast@a16z.com (Ben Horowitz, Marc Andreessen) — Mon, 18 Oct 2021 22:55:59 +0000

This is an excerpt from the a16z Clubhouse show One on One with A and Z, where a16z cofounders Marc Andreessen and Ben Horowitz answer questions on tech trends, company building, and more. To catch full live episodes of the show, follow the a16z Club on Clubhouse.

Good Time Show: Performance with Purpose with Indra Nooyi

content+a16zpodcast@a16z.com (Indra Nooyi, Sriram Krishnan, Aarthi Ramamurthy) — Wed, 6 Oct 2021 01:18:04 +0000

Indra didn't plan her career -- and that was a good thing [2:15]
The personal tradeoffs of professional success [4:24]
Deciding between a job at GE and PepsiCo [7:27]
Rising up the ranks of PepsiCo [12:13]
Transitioning PepsiCo to healthier foods... and doing well by doing good [16:34]
Management hack: writing letters to parents [19:04]
"Performance with Purpose" -- what is it and why does it matter? [22:15]
Work-life balance requires tradeoffs [23:24]
Meeting Steve Jobs and learning the power of design [31:02]
The loneliness of leadership [33:15]

This is an excerpt from the Good Time Show on Clubhouse. To catch full live episodes of the show, follow the a16z Club on Clubhouse.

One on One with A and Z #11: How much rare knowledge is there?

content+a16zpodcast@a16z.com (Marc Andreessen, Ben Horowitz) — Tue, 28 Sep 2021 19:09:00 +0000

Good Time Show: What It Takes to Survive with Lyft Founder John Zimmer

Wed, 8 Sep 2021 23:07:11 +0000

The early days of Zimrides [2:08]
Driving early virality [7:56]
Competing with Uber [15:47]
Why they took political stances [27:03]
Managing through the pandemic [38:09]
The future focus for Lyft -- autonomous vehicles and the end of car ownership [42:50]

Follow the a16z Club to join conversations with tech founders, builders, and leaders live and in-full.

a16z Bio + Health #18: What will it take to cure diabetes?

Fri, 3 Sep 2021 19:19:12 +0000

An overview of diabetes Type 1 and Type 2 [2:58]
Thinking beyond Type 1 and Type 2 [6:58]
New treatment options: stem cells, continuous glucose monitoring [14:19]
What's the timeline on stem cell therapies? [17:15]
Therapies for controlling, rather than curing, diabetes [23:52]
The current technology challenges to treating diabetes [29:52]
The challenges in education and access [35:41]

This is an excerpt from the a16z Bio show on Clubhouse, where we explore all the ways that biology is technology. To catch full episodes of the show, follow the a16z Club on Clubhouse.

a16z Bio + Health #17: Proteomics and Product around a Technological Breakthrough

content+a16zpodcast@a16z.com (Parag Mallick, Vijay Pande, Jorge Conde) — Tue, 31 Aug 2021 23:56:50 +0000

Founding story of Nautilus [1:43]
Why was the Nautilus approach to proteomics a breakthrough? [6:12]
Why a startup instead of academic research? [9:57]
How to pick a good cofounder (it's not that different from choosing a spouse) [15:32]
Advice for academic founders: how to work with VCs [21:14]
The tipping points of scale & the challenges of finding good talent [25:17]
Is proteomics really a gamechanger? [30:49]
How is Nautilus bringing it to market? [34:17]
What Nautilus can learn from Illumina and genomics [37:32]
Looking ahead to the next 10 years [41:26]

This is an excerpt from the a16z Bio show on Clubhouse, where we explore all the ways that biology is technology. To catch full episodes of the show, follow the a16z Club on Clubhouse.

One on One with A and Z #10: The Impact of System Design on Culture

content+a16zpodcast@a16z.com (Ben Horowitz, Marc Andreessen) — Wed, 25 Aug 2021 18:06:04 +0000

This is an excerpt from the a16z Clubhouse show One on One with A and Z, where a16z cofounders Marc Andreessen and Ben Horowitz answer questions on tech trends, company building, and more live . To catch full episodes of the show, follow the a16z Club on Clubhouse.

Capital Markets #1 with MSCI CEO Henry Fernandez: What goes into an index?

content+a16zpodcast@a16z.com (Henry Fernandez, Scott Kupor, Alex Rampell) — Mon, 23 Aug 2021 19:37:49 +0000

The MSCI origin story [1:07]
How does an index get constructed? [6:51]
How do you keep an index accurate? [11:42]
MSCI business model... how do they get paid? [16:27]
MSCI, competition, and why not an open source index? [23:14]
ESG and investment objectives [27:00]
ESG disclosure frameworks and the role of government in ESG [32:50]
Defining ESG [34:44]
MSCI, crypto, and other asset classes [42:55]
Why an index business instead of principal investing? [51:09]

Follow the a16z Club to join conversations with tech founders, builders, and leaders live and in-full.

Good Time Show: Metaverse + Crypto

content+a16zpodcast@a16z.com (a16z) — Wed, 18 Aug 2021 03:05:38 +0000

SPEAKERS:

Aarthi Ramamurthy, international, Clubhouse
Donnie Dinch, founder and CEO, Bitski
Gabby Dizon, cofounder, Yield Guild Games
Jarrod Dicker, operating partner, TCG
Jesse Walden, founder, Variant Fund
Jon Lai, principal, a16z
Packy McCormick, founder, Not Boring
Sriram Krishnan, general partner, a16z
Twobadour, founder, Metapurse
Justin “3LAU” Blau, producer and musician

originally aired on Clubhouse https://twitter.com/sriramk/status/1422987628958208007

a16z Infra #6: The Cost of Cloud vs. Repatriation

Tue, 27 Jul 2021 22:18:07 +0000

This conversation centers on the arguments and findings of the a16z piece The Cost of Cloud, a Trillion Dollar Paradox.

The Core Findings of The Cost of Cloud piece [5:22]
Cloud is a significant part of COGS for public SaaS companies [8:38]
Should you allocate engineers to reduce cloud cost or just focus on growth? [12:06]
How much of a problem is not knowing cloud spend? [15:56]
The tradeoff between focusing cost and engineering resources [19:33]
Should large public SaaS companies repatriate? [23:41]
Performance matters -- it's not all about cost [31:55]
Is all the talent for running data centers at the Google, AWS, and Azure? [37:46]
Will the cloud feature set become commoditized? [44:57]
Cloud oligopoly and market dynamics [50:39]

Follow the a16z Club to join conversations with tech founders, builders, and leaders live and in-full.

Good Time Show: a16z's Journey with Crypto and Crypto Investing

Mon, 19 Jul 2021 22:33:01 +0000

This podcast is an excerpt. Follow the a16z Club to join conversations with tech founders, builders, and leaders live and in-full.

Early days of a16z crypto [2:38]
New crypto governance capabilities [16:34]
How is the VC model different when investing in crypto? [22:24]
Crypto regulation and the recent attempt at holiday rulemaking [29:49]
Is anyone effectively regulating crypto? [34:15]
How do you start working in crypto? [36:58]
What problems should crypto founders work on? [43:51]
Identity, crypto, and the future of social networks [45:15]
Centralized vs. decentralized: the battle for the internet [48:17]

a16z Infra #5: Category Creation with Armon Dadger (HashiCorp) and Stephen Mullaney (Aviatrix)

Fri, 16 Jul 2021 18:04:44 +0000

What makes a category? [0:37]
The leading indicator? Everyone thinks you're crazy. [5:36]
Can you create a category whole cloth? [7:02]
How to create a category [12:05]
The best category creation CEOs are product marketers [15:55]
Category creation tactics: certification programs [18:54]
Category creation tactics: persona-based storytelling [22:17]
Is there a repeatable way to make a category? [25:35]
The role of the CTO and product teams in creating the message [29:22]
How do you structure product marketing? [45:16]

This is an excerpt from the a16z Clubhouse show a16z Infra. To catch full episodes of the show, follow the a16z Club on Clubhouse.

People Behind the Product #3: What's Next in Retail?

Wed, 14 Jul 2021 21:03:11 +0000

SPEAKERS (in order they are heard in the episode):

Shannon Kelly, a16z
Connie Chan, a16z
Brandon Chu, VP Product and GM of Platform, Shopify
D'Arcy Coolican, a16z
Nait Jones, a16z
Jess Lee, Cofounder and CEO, Modern Citizen
Imran Khan, Co-founder and CEO, Verishop

This is an excerpt from the a16z Clubhouse show People Behind the Product. To catch full episodes of the show, follow the a16z Club on Clubhouse.

4B with Margit #9: What Exactly Is Growth Hacking?

Wed, 23 Jun 2021 22:46:25 +0000

The origins of growth hacking [1:20]
Brand building vs. growth hacking? [13:58]
Where does growth fit into the organization? [31:06]
The cold start problem: growth hacking from 0 to 1 [36:47]
What can't be measured? [47:53]
How do you test and validate new channels? [51:38]
Do growth hacks always work, or at some point does it come down to product? [54:55]
How do you allocate budget? [1:00:27]

For the latest a16z conversations on Clubhouse, follow the a16z Club.

Future.com: The Why, The What, and The Who

Tue, 22 Jun 2021 19:37:43 +0000

Why Future with Marc Andreessen, Margit Wennmachers, and Sonal Chokshi [2:20]

The New Creator Economy with Joost van Dreunen, Wes Kao, Cuy Sheffield, Chris Lyons, Lauren Murrow, and Zoran Basich [17:58]

Bubbles, Speculation, and Innovation with Byrne Hobart, Jamie Catherwood, and Zoran Basich [35:38]

Work Models & Measures for the Information Age with Rajiv Ayyangar, Nicole Forsgren, and Das Rush [51:20]

The Power of Subtracting, Adding, and AI in Bio with Leidy Klotz, Vijay Pande, and Lauren Richardson [1:05:11]

***

Visit future.a16z.com for additional content on these topics and more.

Follow the a16z Club on Clubhouse to join conversations with tech founders, builders, and leaders live and in-full.

One on One with A and Z #9: The Big Questions around Remote Work

content+a16zpodcast@a16z.com (Marc Andreessen, Steven Sinofsky, Ben Horowitz) — Fri, 18 Jun 2021 22:21:06 +0000

What was the biggest surprise from the past 15 months of remote work? [5:24]
How do you handle conflict and build trust? [10:09]
What's the role of offsites? [15:45]
Should you adjust compensation for different geographies? [24:02]
How do you measure productivity? [34:10]
What is the impact of remote work on retention and turnover? [49:17]
How do startups built on decentralized platforms (e.g., Ethereum) function? [53:36]
Is this the beginning of the end for Silicon Valley? [56:07]

For the latest a16z conversations on Clubhouse, follow the a16z Club.

Good Time Show with Plaid CEO Zach Perret

Fri, 18 Jun 2021 19:26:33 +0000

This podcast is an excerpt. Follow the a16z Club to join conversations with tech founders, builders, and leaders live and in-full.

In this episode:

The abandoned M&A with Visa [3:47]
Communicating to employees around the M&A [8:29]
Plaid's near death experiences in the early days [12:41]
The fintech trends that made Plaid possible [17:29]
What is a bank now? [26:54]
Fintech and new revenue models [29:20]
Plaid's role in the creator economy [35:21]
What is a neobank? [37:30]

a16z Bio + Health #16: Digital Health for Complex Care

Thu, 17 Jun 2021 22:51:43 +0000

In what ways is digital health for complex care under or overrated? [4:04]
Are digital health solutions better suited to tackling clinical or non-clinical needs for complex care? [17:32]
The challenge of the physician's inbox [27:55]
Have we meaningfully moved the needle on complex digital care? If so, where? [32:08]
Should we focus on applying basic tech to easy optimization and automation problems or advanced tech to more complex problems? [41:48]

It's Time to Heal, Mondays at 5pm PT on Clubhouse. Join the a16z bio team — Jorge Conde, Vineeta Agarwala, Julie Yoo, and Vijay Pande — plus special guests as they explore all the ways that biology is technology.

Good Time Show: DAO Primer

Tue, 15 Jun 2021 00:10:44 +0000

Decentralized autonomous organizations, or DAOs, are one of the hottest topics in crypto and tech right now. But what exactly are they? Why do they matter? And what new modes of governance, ownership, and creation do they make possible?

a16z Bio + Health #15: The mRNA Revolution with Moderna CEO Stephane Bancel

Fri, 11 Jun 2021 00:47:34 +0000

mRNA research before COVID and how "mRNA is code" [3:21]
The early days of COVID: designing a vaccine in 48 hours [5:44]
The software behind the vaccine: getting mRNA researchers out of Excel and into a drug design studio [9:11]
The first draft of the vaccine was the final draft [11:10]
How the government sped up vaccine development for COVID [12:18]
What other new vaccines will come from mRNA? [15:34]
How far are we from these mRNA vaccines? What do we need for them to be widely available? [25:31]
Open sourcing Moderna [27:53]
When will COVID vaccines be available for a five year old? [29:47]
The three factors that matter when dealing with COVID variants [30:46]
How might open source shake up biotech [36:41]
The moonshot applications for mRNA therapeutics [39:43]
Advice for building a new category in a regulated environment [46:49]
The clinical or regulatory advances needed to speed drug time to market [51:08]
Challenge trials for vaccines: good or bad idea? [59:11]

Boss Talk #15: Copycats, Inventors vs. Operators. Hiring SDRs, and more

content+a16zpodcast@a16z.com (Ali Ghodsi, Ben Horowitz, Fab 5 Freddy) — Fri, 28 May 2021 22:49:45 +0000

Fab 5 Freddy on New York in the 70s, Warhol, Blondie, Basquiat, and Yo! MTV Raps [1:40]
Contrarian strategy and challenging assumptions [5:12]
Boring AI and solving meaningful problems [8:42]
Drop-in audio copycats [14:39]
How is copying software different from remixing hip hop? [21:07]
Do you want a CEO as an inventor or an operator? [24:12]
Recruiting sales development reps [30:34]
Being a boss and having a personal life [36:56]
How do you tell the story of letting someone go? [42:47]
Best practices for delegating responsibility [49:46]
Worst boss advice Ben and Ali have received [57:15]

Boss Talk is the Clubhouse show where a16z cofounder Ben Horowitz and Ali Ghodsi, the Founder/CEO of Databricks, discuss CEO stuff, leadership stuff, management stuff... boss stuff. Live every Tuesday 5-6pm on Clubhouse.

For more a16z Clubhouse shows, follow the a16z Club on Clubhouse or visit www.a16z.com/clubhouse.

GTM #2: Product-led Marketing

Mon, 24 May 2021 23:18:40 +0000

The six functions in an enterprise marketing org [2:54]
Why product marketing is the killer function [6:52]
How do you hire a world class product marketer? [11:16]
Is community or developer evangelists its own function or part of product marketing? [17:46]
How does community tie into the marketing funnel? [22:56]
Is community top of funnel, an accelerant for the whole funnel, or something else entirely? [29:39]
If the product you're selling becomes someone's job, then your community marketing is working. [32:40]
Plugging the community into sales... is there a tool for that? [34:29]
How do all the different marketing tools come together? Do you need engineers in marketing? [39:24]
How do you make marketing data-driven? [41:56]
Building marketing in the early stages [50:06]

Inside sales, field sales, product-led, channel sales, marketing, post-sales… On a16z GTM, David Ulevitch talks to builders about what it takes to go to market, and the evolving strategies and lessons learned from enterprise companies past and present. Every other Thursday 4-5pm.

For more a16z Clubhouse shows, follow the a16z Club on Clubhouse or visit www.a16z.com/clubhouse.

Boss Talk #14: New Media Models with Substack

Fri, 21 May 2021 18:16:39 +0000

What did Substack think about the NYTimes article "Why We’re Freaking Out About Substack" [1:01]
What is Substack? [4:40]
The issues with social media content models and how Substack is different [5:54]
What about the echo chamber? [8:54]
Turning cultural principles (e.g., freedom of the press) into actual culture [12:00]
Will Substack replace traditional media? [14:01]
Would Donald Trump be welcome on Substack? [20:35]
Why do they pay writers advances? And why is that controversial? [23:33]
The origins of American journalism aren't what most people think [27:20]
Non-fungible writers and the Substack model [31:45]
Ad-supported media predates the internet [39:21]
How do I price my Substack? [43:39]
Substack, political topics, and culture wars: "We knew we were running towards the fire." [45:01]
How do you prevent algorithms from slanting the platform [51:06]
Substack's vision for the future of media [55:27]

For more a16z Clubhouse shows, follow the a16z Club on Clubhouse or visit www.a16z.com/clubhouse.

People Behind the Product #2: Collectibles Comeback

Thu, 20 May 2021 17:06:10 +0000

eBay to today, a brief history of collectibles and tech [1:03]
Are collectibles about sentiment or investment? [5:13]
How do you bring the excitement of a collection to digital goods? [13:34]
Is the future of all collectibles digital? [20:20]
The role of blockchain and NFTs [26:39]
Are collectible marketplaces different from other marketplaces? [32:19]
Importance of live video [38:28]
Celebrity interest in NFTs: will it last? [40:46]
Are collectibles a bubble? [43:13]

Listen live to the a16z show People Behind the Product Wednesdays noon-1pm PT with the a16z consumer team.

NFT Virtual Summit (full audio)

Wed, 19 May 2021 01:00:31 +0000

For videos of the NFT Virtual Summit, visit a16z.com.

Session 1: The Future of the Digital Ownership Economy with Dan Boneh (Stanford University) and Chris Dixon (a16z)

What is an NFT? [3:01]
Why are NFTs so big right now? [7:04]
The most exciting programmable ownership structures [11:36]
NFTs and composability: what can you do with NFTs? [15:16]
How would quantum impact the immutability of the blockchain ledger? [18:40]
How important is decentralized permanent storage for NFTs... and when will we get there? [20:54]

Session 2: The New Creative Economy with Kayvon Tehranian (Foundation Labs)

How Foundation Labs works with creatives [24:54]
Digital Art NFTs: Nyan Cat, Ethiopian Artists Collective, Rafael Rozendaal, Aphex Twin, and Reuben Wu [28:08]
The Edward Snowden NFT [33:45]
Why is tracking provenance powerful for creatives? [36:34]
Creators becoming collectors and crypto investors [39:00]
Can you buy an NFT on one platform and sell on another and still track provenance? [41:31]

Session 3: NBA Top Shot and Other NFTs on the Flow Blockchain with Dan Boney (Stanford University) and Dieter Shirley (Dapper Labs)

The Flow Blockchain from CryptoKitties to NBA Top Shot [45:18]
What is NBA Top Shot, and what was the hardest part of building it [50:34]
Building a successful user experience [52:55]
Negotiating with the NBA [54:32]
The biggest challenges for NFTs going mainstream [56:55]
Why did they build their own blockchain? [1:01:23]
Building ERC-721 and lessons learned on crypto standards [1:04:00]

Session 4: Going Beyond Collectibles and The Future of Tokens for Creators with Kevin Chou (Rally) and Chris Dixon (a16z)

What are social tokens? (and how is Portugal. The Man. using them) [1:05:51]
What are the roles of fungible and non-fungible tokens? [1:08:30]
NFTs in gaming now and what's next [1:14:35]
Pricing and price discovery for NFTs [1:17:39]
Tips for launching a social token [1:19:06]
How does Rally make money? [1:22:08]

Session 5: NFT Use Cases Today and Tomorrow with Devin Finzer (OpenSea) and Katie Haun (a16z)

What does OpenSea do? [1:26:14]
Why the sudden interest in NFTs? [1:28:35]
What can and can't be turned into an NFT [1:30:13]
How NFTs can interact with the physical world [1:32:33]
Virtual lands and the metaverse economy [1:35:14]
Virtual concerts and NFT tickets [1:40:44]
Mixing and remixing NFTs [1:43:04]

Session 6: The Accidental Art DAO with pplpleasr (digital artist)

pplpleasr's NFT "Apes Together Strong" that was auctioned as part of The NFT Summit serves as the artwork for this podcast.

a16z Bio + Health #14: How do we safely deliver more gene therapies?

Tue, 18 May 2021 17:33:46 +0000

What inspired Eric and Sam to start Dyno [4:09]
How does the use of ML impact Dyno's GTM [10:40]
The current challenges of gene therapy [21:43]
Why Dyno wants to be a horizontal platform for gene therapy [30:56]
How does Dyno think about competition [44:23]
After party and audience Q&A [52:01]

It's Time to Heal, Mondays at 5pm PT on Clubhouse. Join the a16z bio team — Jorge Conde, Vineeta Argawala, Julie Yoo, and Vijay Pande — plus special guests every week as they explore all the ways that biology is technology.

Boss Talk #13: Book Club for Bosses

content+a16zpodcast@a16z.com (Ali Ghodsi, Ben Horowitz, Marc Andreessen) — Fri, 14 May 2021 22:25:00 +0000

Note: the recording of this episode starts a minute or two into the show.

Ali recommends: The Hard Thing about Hard Things by Ben Horowitz [0:18]
Ben recommends: High Output Management by Andy Grove [4:36]
Marc recommends: Who Really Matters: The Core Group Theory of Power, Privilege, and Success by Art Kleiner [10:48]
Best read for enterprise sales: Power Base Selling by Jim Holden, et al [13:06]
Microsoft, Google, government contracts, and politicized workplaces [16:28]
Marc recommends: The Tyranny of Structurelessness by Jo Freeman [29:32]
Ali recommends: Radical Candor by Kim Scott [33:19]
Ben recommends: No Rules Rules: Netflix and the Culture of Reinvention by Erin Meyer and Reed Hastings [44:19]
Ben recommends: Working Backwards: Insights, Stories, and Secrets from Inside Amazon by Colin Bryar [50:28]
How they are approaching the return to work and remote work [53:00]

For more a16z Clubhouse shows, follow the a16z Club on Clubhouse or visit www.a16z.com/clubhouse.

Ben Feder of Tencent America on Games Club

Fri, 14 May 2021 18:05:17 +0000

How Ben took over Take Two [1:42]
How digital distribution and publishing changed gaming [8:36]
What is a next generation publisher? [13:51]
Can publishers add value as tastemakers? [17:36]
How do you make sure studios ship on time? And in the era of persistent game worlds, does it matter? [22:01]
Lessons learned from Take Two [27:27]
Taking the long view of the creative process — "Every overnight success was ten years in the making." [30:53]
Is there a successful game that surprised Ben? [37:08]
What's the next big gaming platform? [46:07]
Where will subscription models lead? [52:06]
Sabbaticals and life advice [56:50]

Join a16z partners and special guests from the gaming industry for discussions on games, game development, online communities, esports, AR/VR, and everything in between. Wednesdays at 5pm PT.

For more a16z Clubhouse shows, follow the a16z Club on Clubhouse or visit www.a16z.com/clubhouse.

Robert Smith on Unfettered Conversations with A and Z

content+a16zpodcast@a16z.com (Marc Andreessen, Ben Horowitz, Robert Smith) — Thu, 13 May 2021 17:12:45 +0000

Robert's foundational experiences growing up [3:03]
His introduction to computers, how he got an internship at Bell Labs, and what he learned there [6:38]
Why he studied chemical engineering [13:15]
Working at Kraft and engineering macaroni and cheese [15:08]
Why he moved to investing [18:12]
How he realized that it made sense to do buyouts in enterprise software [23:19]
Creating a common playbook for running enterprise software companies [30:45]
How does he think about retaining vs replacing founders [34:54]
Vista's approach to evaluating talent and getting people in the right roles [37:02]
Robert's next ambition [46:10]
His philosophy of philanthropy [49:15]
Why he paid off the student debt for Morehouse College Class of 2019 [1:00]

For our upcoming schedule of Clubhouse conversations, follow the a16z Club on Clubhouse or visit a16z.com/clubhouse.

4B with Margit #8: Basecamp and Banning Political Talk

content+a16zpodcast@a16z.com (Das Rush, Margit Wennmachers, Tina Wie) — Thu, 13 May 2021 00:37:01 +0000

What happened at Basecamp and could it have gone differently? [3:51]
When did Basecamp turn into a 4B? [7:45]
Why were buyouts a good policy for Basecamp and Coinbase? [10:26]
Why not have a more moderate policy? [11:56]
What makes something "political"? [14:45]
What about when political issues have a personal impact on employees? [19:18]
What happened at Peloton and why they apologized [22:53]
When should you issue an apology? [26:12]
How do you rebuild trust after you apologize? [28:32]
Audience Q&A [33:44]

"4B with Margit" is a Clubhouse show for raw and unfiltered advice from comms and marketing experts who have seen it all, as well as insider stories from the builders and pioneers who were in the trenches. Think “Scandal” meets “Halt and Catch Fire.” Catch it live Wednesdays 4-5 PST.

For our upcoming schedule of Clubhouse conversations, follow the a16z Club on Clubhouse or visit a16z.com/clubhouse.

Breach of the Week #4: Red Teaming iOS Vulnerabilities with Cedric Owens

content+a16zpodcast@a16z.com (Geoff Belknap, Joel de la Garza, Cedric Owens) — Tue, 11 May 2021 21:18:30 +0000

What are red teams and blue teams? [2:03]
How Cedric cracked Mac Gatekeeper [6:55]
Apple's response [15:22]
Cedric's craziest hack [19:24]
Red team advice for the blue team [22:02]
Audience Q&A [26:31]

🔐Breach of the Week 🔐looks at who got hacked, how it happened, and what it means for the industry.

🎙With hosts Joel de la Garza (a16z Security Operating Partner) and Geoff Belknap (CISO LinkedIn) on Clubhouse every Thursday 5-5:30pm.

a16z Bio + Health #13: Care After COVID with Shantanu Nundy

Tue, 11 May 2021 00:36:45 +0000

On this episode of the a16z Bio Clubhouse Show, a16z general partners Vineeta Agarwala, Julie Yoo, Vijay Pande, and Jorge Conde talk to guest Shantanu Nundy, the Chief Medical Officer of Accolade. The conversation covers Dr. Nundy's new book, "Care After Covid: What the Pandemic Revealed Is Broken in Healthcare and How to Reinvent It", the next steps in the evolution of hospitals, interoperability (or lack thereof), and more.

a16z Infra #4: Segmenting the Data Analytics Stack

Fri, 7 May 2021 23:18:15 +0000

Why does it feel like there's a database for everything? [4:46]
What is the actual use case and market for streaming? [9:34]
How real is real time? [20:12]
Can you do everything in SQL? [25:08]
Is the future SQL extensions or does SQL become embedded in data frames? [40:19]
Is database consolidation coming? How many different systems will we have? (SPOILER: 3... maybe) [49:41]

a16z Infra is the Clubhouse Show where the a16z enterprise team and guests discuss the foundational technology and products that underpin all of tech. We dig deep into data, AI/ML, security, developer tools, compute, network, storage, hardware, and anything else found below the surface of modern stacks.

Like what you hear? Tune in for our next show on Thursday, May 13, 11am-noon.

Boss Talk #12: The AI Edition

Fri, 7 May 2021 22:42:03 +0000

What is AI? [2:27]
AI is statistics, not consciousness [7:05]
Why then so much talk about the singularity? [12:12]
AI breakthroughs and FAANGs [17:21]
Building the AI toolchain [26:07]
AI applications in bio and medicine [30:19]
Ali's favorite AI use cases [34:35]
What will AI do to jobs? [39:27]
AI in 10 years [46:09]
Snowflake, Databricks, data Lake, data warehouse, and how it all fits together [48:16]

4B with Margit #7: Building Brand Communities

Thu, 6 May 2021 21:58:36 +0000

In this episode:

Melody McCloskey - CEO of StyleSeat, a booking platform that connects stylists and beauty professionals with clients. Since its founding in 2011, StyleSeat has powered 150 million beauty appointments and generated over $6.5 billion in revenue for beauty professionals. The company has created a loyal community of the country’s leading hair, makeup and nail stylists.
Camille Ricketts - Head of Marketing at Notion, a popular workspace collaboration and productivity tool that has developed an almost cult-like following of users.
Eric Lam - Founder of AspireIQ, an influencer marketing and community building platform that works with big brands like Walmart and Marriott as well as with startups to help them identify and activate their most valuable brand advocates, empowering them to share their passion for their favorite brands with the world.

For our upcoming schedule of Clubhouse conversations, visit a16z.com/clubhouse.

a16z Bio + Health #12: Talking Price Transparency and Patient Engagement with Florian Otto

Wed, 5 May 2021 20:18:40 +0000

On this episode of the a16z Bio Clubhouse Show, a16z general partners Julie Yoo and Jorge Conde, managing partner Scott Kupor, and market development partner Venkat Mocherla talk to guest Florian Otto, cofounder and CEO of Cedar. The conversation covers how to improve two of the trickiest aspect of healthcare: price transparency and patient engagement.

Boss Talk #11: Second Time Founder with Sanjit Biswas (Samsara)

content+a16zpodcast@a16z.com (Ali Ghodsi, Ben Horowitz, Sanjit Biswas) — Tue, 4 May 2021 00:48:55 +0000

GTM #1: The New Enterprise Go to Market with Figma

Fri, 30 Apr 2021 21:58:01 +0000

Inside sales, field sales, product-led, channel sales, marketing, post-sales… a16z GTM is our clubhouse show for enterprise founders and builders about what it takes to go to market and the evolving strategies and lessons learned from enterprise companies past and present. Every other Thursday 4-5pm with David Ulevitch.

For our upcoming schedule of Clubhouse conversations, visit a16z.com/clubhouse.

One on One with A and Z #8: Which will last longer Harvard or the US?

content+a16zpodcast@a16z.com (Marc Andreessen, Ben Horowitz) — Thu, 29 Apr 2021 16:31:27 +0000

a16z cofounders Marc Andreessen and Ben Horowitz answer questions on tech trends, company building, and more live on Clubhouse Mondays at 7pm PT.

In this conversation:

Which institution will last longer Harvard or the US? [00:58]
How do you craft a good culture in a high pressure environment? [13:45]
When will we have AGI? [31:15]
Are network effects today so strong that big tech incumbents (e.g., Google, Facebook, Amazon) can deliver better products than startups? [44:06]
What actually is the internet? [50:03]

For our upcoming schedule of Clubhouse conversations, visit a16z.com/clubhouse.

4B with Margit #6: How Startups Can Work with Government and Policy Makers

Wed, 28 Apr 2021 19:48:37 +0000

In this episode:

Jim Messina - CEO, The Messina Group; formerly Obama's Deputy Chief of Staff; known as the "fixer" and "the most powerful person in Washington you've never heard of"
Adrian Durbin - currently at Greenbrier; former Director of Policy Comms at Lyft
Risa Heller - CEO of Risa Heller Communications; former Director of Comms for Senator Charles Schumer

For our upcoming schedule of Clubhouse conversations, visit a16z.com/clubhouse.

a16z Bio + Health #11: The Digital Health OGs

Wed, 28 Apr 2021 15:30:21 +0000

On this episode of the a16z Bio Clubhouse Show, a16z general partners Vineeta Agarwala, Julie Yoo, and Jorge Conde talk to guests Sean Duffy, cofounder and CEO of Omada Health, Karan Singh, cofounder and COO of Ginger, and Chris Hogg, a serial entrepreneur in the digital health space. The conversation covers go-to-market strategies, financing and aligning incentives, the struggles of interoperability (or lack thereof), and what it is like to build today versus in the early years.

People Behind the Product #1: YouTube and the Evolution of the Creator Economy

Tue, 27 Apr 2021 16:58:35 +0000

In this episode:

Jamie Byrne, Senior Director of Creator Partnerships, YouTube
Shishir Mehrotra, former Director of Product Management, YouTube; former VP of Product, Engineering, UX, YouTube; current Founder & CEO, Coda
Shiva Rajaraman, former Director, Product Management (etc.); current VP Shops and Business, Facebook
Lauren Riihimimaki (aka LaurDIY), Canadian YouTuber

One on One with A and Z #7: The NFT Renaissance

content+a16zpodcast@a16z.com (Ben Horowitz, Marc Andreessen) — Fri, 23 Apr 2021 16:57:45 +0000

a16z cofounders Marc Andreessen and Ben Horowitz answer questions on tech trends, company building, and more live on Clubhouse Mondays at 7pm PT.

In this conversation:

NFTs and tokenization — how will they impact the arts, media, music and investing strategies?
The potential for DeFi
Using shocking new rules to create culture
Structuring options to attract talent
Spending time in the markets vs. timing the market
Operation Warp Speed — will it accelerate how novel medical treatments come to market?
Younger workers and building professional connections in a hybrid world

a16z Infra #3: What Microsoft Can Teach Us about Technical Product Leadership at Scale

Wed, 21 Apr 2021 18:18:13 +0000

Like what you hear? Tune in for our next show on Thursday, April 29, 4-5pm.

a16z Bio + Health #10: The Digital Health Difference with Connie Chen

Wed, 21 Apr 2021 15:43:43 +0000

On this episode of the a16z Bio Clubhouse Show, a16z general partners Vineeta Agarwala, Julie Yoo, and Jorge Conde talk to guest Connie Chen, Chief Medical Officer at Lyra health. The conversation covers what makes digital health different from traditional healthcare delivery, how to build a sustainable business model while maintaining high standards for care, and advice for founders of digital health startups.

Technology & Talent for Defense with Anduril

Tue, 20 Apr 2021 03:10:58 +0000

Anduril founders and team members Joe Chen, Matt Grimm, Palmer Luckey, Brian Schimpf, and Trae Stevens in conversation with Big Ideas show on Clubhouse co-host Katherine Boyle (along with Antonio Garcia-Martinez, Erik Torenberg, and Marc Andreessen).

Boss Talk #10: The Story is the Strategy with Dave McJannet

Mon, 19 Apr 2021 18:31:54 +0000

On this episode of Boss Talk:

How do the best product marketers see and explain a trend?
How much is the best marketing truth vs. spin?
Does the marketing function create the strategy or execute on it?
What are the core skills and competencies of a great product marketer — and how do you find, or train, product marketers?
Should you create a category, or try to capture an existing category?
What is the minimum viable audience ?
What's the role of open source in getting a minimum viable audience?
How should an open source company handle DevRel, licensing, and big cloud competitors?

The Good Time Show: The Coinbase Story

Fri, 16 Apr 2021 17:54:46 +0000

From first discovering the bitcoin white paper through the crypto winters to taking the company public... Coinbase founders Brian Armstrong and Fred Ehrsam tell their story, with Good Time Show hosts Aarthi Ramamurthy and Sriram Krishnan, plus early investors, employees, and board members — Garry Tan, Marc Andreessen, Dan Romero, Balaji Srinivasan, and Katie Haun.

Zynga cofounder Justin Waldron on Games Club

Fri, 16 Apr 2021 17:54:35 +0000

Zynga cofounder and SVP of Product Justin Waldron discusses his early iteration process, reimagining the game industry's business model, and important game metrics with a16z partner Jonathan Lai, Stillfront SVP Andrew Green, Presence Capital managing partner Amitt Mahajan, and Indie MEGABOOTH founder Kelly Wallick on Games Club.

Breach of the Week #3: Ubiquiti and Whistleblowing

content+a16zpodcast@a16z.com (Geoff Belknap, Joel de la Garza) — Thu, 15 Apr 2021 16:49:30 +0000

In January, device maker Ubiquiti disclosed a breach and urged customers to change passwords. Then in late March, a whisteblower alleged that Ubiquiti had massively downplayed the severity and extent of the breach to preserve the stock price. So, how bad was the breach? What do we, and don't we, know? What does this tell us about best practices for disclosures in the aftermath of a breach? And what is the role of whistleblowers?

🔐Breach of the Week 🔐looks at who got hacked, how it happened, and what it means for the industry.

🎙With hosts Joel de la Garza (a16z Security Operating Partner) and Geoff Belknap (CISO LinkedIn) on Clubhouse every Thursday 5-5:30pm.

Steve Stoute on Unfettered Conversations with A and Z

Wed, 14 Apr 2021 01:28:46 +0000

In this occasional Clubhouse series, a16z co-founders Marc Andreessen and Ben Horowitz talk with Steve Stoute, the founder and CEO of UnitedMasters and a former executive at Interscope and Sony Music, about the changing music business, the role of technology, how Steve started UnitedMasters, and more. Special guests MC Hammer and Fab 5 Freddy also joined.

A Crisis of Trust with Richard Edelman, Emily Chang, and Helena Maus on 4B with Margit

Tue, 13 Apr 2021 21:16:35 +0000

Every year, Edelman publishes a trust barometer. This year, trust in most of our social institutions — and especially in media — was down. Margit asks Richard Edelman (CEO of Edelman), Emily Chang (Executive Producer at Bloomberg), and Helena Maus (CEO of Archetype) how real is the crisis of trust in media and beyond; what’s behind it; how does it relate to the perceived friction between tech and the media… and what will it take to (re)build trust.

Beating the Incumbents with Michael Ovitz on Boss Talk #9

Fri, 9 Apr 2021 23:27:34 +0000

When Ben and Marc started a16z, CAA and its founder Michael Ovitz served as inspiration for how to break into an industry dominated by a few large incumbents. In 1975, a few large talent agencies dominated the entertainment industry. To break into the industry, Michael and CAA came up with a new playbook — rather than a single agent representing an actor or actress, he turned the entire agency into a network. In this special edition of Boss Talk, Michael joins Ben, Marc, and Ali to talk about how both CAA and a16z went from scrappy startup to industry leader by giving talent access to bigger networks.

a16z Bio + Health #9: Engineering CRISPR with Ben Oakes

content+a16zpodcast@a16z.com (Vijay Pande, Ben Oakes, Vineeta Agarwala) — Thu, 8 Apr 2021 17:05:04 +0000

On this episode of the a16z Bio Clubhouse Show, a16z general partners Vineeta Agarwala and Vijay Pande talk to guest Ben Oakes, cofounder, President and CEO of Scribe Therapeutics. The conversation covers the the power of engineering gene editors, the transition from academia to a startup, and how to select the first indication to target with a novel bio platform.

The Future of Open Source in the Era of SaaS on a16z Infra

content+a16zpodcast@a16z.com (a16z) — Tue, 6 Apr 2021 01:47:26 +0000

What is the future of open source in the age of SaaS? Has it become more, or less, relevant with the rise of cloud-based services? What is the connection between open source and open standards? And what does this mean for startups building SaaS apps today? Those questions and more with Nick Schrock (Elementl, GraphQL), Christian Kleinerman (Snowflake), Andrew Shafer (RedHat), and a16z general partners Martin Casado and Peter Levine.

Like what you hear? Tune in for our next show on Thursday, April 15, 4-5pm.

Scaling Marketplace Startups with the CEOs of GOAT, Cameo, Faire, StyleSeat, Neighbor, Whatnot, & more

Fri, 2 Apr 2021 15:47:06 +0000

The CEOs of GOAT, StyleSeat, Cameo, Faire, Whatnot, and Neighbor join a16z partners Andrew Chen, Connie Chan, D'Arcy Coolican, Jeff Jordan, Katie Baynes, and Anne Lee Skates to talk about the cold start problem, 2020 metrics, growth, and the tricky business of scaling a marketplace company.

See more marketplace analysis, including a ranking of the 100 largest marketplace startups & private companies, in the Marketplace 100.

Academic CEOs, Junior v. Senior Engineers, and High Growth Mistakes on Boss Talk #8

content+a16zpodcast@a16z.com (Felicia Horowitz, Ben Horowitz, Ali Ghodsi) — Thu, 1 Apr 2021 20:22:35 +0000

This week on Boss Talk: Why aren't there more academic CEOs? Should early stage companies hire junior or senior engineers? What are the common mistakes high growth companies make, especially when expanding into new markets? Plus: balancing pay equity with retainment, CEO legal risk and protection, and growing through acquisition.

a16z Bio + Health #8: How to Innovate within Biopharma with Jay Bradner

Thu, 1 Apr 2021 07:00:00 +0000

On this episode of the a16z Bio Clubhouse Show, a16z general partners Vineeta Agarwala, Jorge Conde, Julie Yoo, and Vijay Pande talk to guest Jay Bradner, President of the Novartis Institute of Biomedical Research (NIBR). The conversation covers the challenges of translating basic research into a clinical application, the state of innovation in therapeutics, and the transition from drug hunting to drug farming.

Return to Work, Celebrity Investors, Institutional Distrust and More on One on One with A and Z

content+a16zpodcast@a16z.com (Marc Andreessen, Ben Horowitz) — Thu, 1 Apr 2021 03:33:03 +0000

a16z cofounders Marc Andreessen and Ben Horowitz talk tech trends, company building, and more live on Clubhouse every Monday, 7pm PT.

In this conversation:

What does return to work look like for a16z portfolio companies (including exclusive survey data)
How the re-distribution of the workforce might affect rural America
The potential for social networks to replace networking in cities
Generalists vs specialists in a startup
How to think about celebrity investors and executives (like Prince Harry)
The growing distrust of institutions in America
The technology that could still be with us in 500 years
Books of the week! Marc on "Medici Money" by Tim Parks and Ben on "Lenin" by Victor Sebestyen

How Ben's Twitter Got Hacked on Breach of the Week #2

content+a16zpodcast@a16z.com (Joel de la Garza, Geoff Belknap, Ben Horowitz) — Wed, 31 Mar 2021 00:57:54 +0000

What do Ben Horowitz and former President Obama have in common? They both had their twitter accounts taken over to send cryptocurrency spam.

With our office now our home, all security has become personal. This week on Breach of the Week, Ben explains how his Twitter got hacked, and Geoff and Joel break down the personal threat landscape, the security measures that best protect you, and where the security industry needs to evolve to better protect individuals.

🔐Breach of the Week 🔐looks at who got hacked, how it happened, and what it means for the industry.

🎙With hosts Joel de la Garza (a16z Security Operating Partner) and Geoff Belknap (CISO LinkedIn) on Clubhouse every Thursday 5-5:30pm.

Supercell CEO Ilkka Paananen on Games Club

Tue, 30 Mar 2021 21:22:05 +0000

Supercell CEO and co-founder Ilkka Paananen discusses collaborative decision-making on game teams, learning from failure, product design, building company culture, and more with a16z partner Jonathan Lai, Stillfront SVP Andrew Green, Proletariat CEO Seth Sivak, and Indie MEGABOOTH founder Kelly Wallick on Games Club.

a16z Bio + Health #7: The Power of Patient Data with Anne Wojcicki

Tue, 30 Mar 2021 18:00:00 +0000

On this episode of the a16z Bio Clubhouse Show, a16z general partners Vineeta Agarwala, Jorge Conde, Julie Yoo, and Vijay Pande, along with a16z cofounder Marc Andreessen, talk to guest Anne Wojcicki, CEO of 23andme. The conversation covers the shifting trends and perceptions at the intersection of bio and tech, the power of patient data and importance of giving people access to their own health data, and advice to founders on when to lead and when to listen.

Crypto Clubhouse: NFTs, NFTs, NFTs! with OpenSea + Katie Haun

Tue, 30 Mar 2021 07:01:55 +0000

OpenSea founders Devin Finzer and Alex Atallah join Katie Haun as well as Marc Andreessen and Chris Lyons to talk about the emergence of NFTs, what it means for crypto marketplaces, and how the creator economy will continue to evolve.

The Art of Public Speaking with Matt Abrahams (Stanford), Ritu Narayan (Zūm) and Amir Movafaghi (Mixpanel) on 4B with Margit

Fri, 26 Mar 2021 20:26:38 +0000

Speaking coach extraordinaire Matt Abrahams, cofounder of Bold Echo LLC and Lecturer at Stanford Graduate School of Business; Zūm CEO Ritu Narayan; and Mixpanel CEO Amir Movafaghi talk with Margit about how to master the art of public speaking, communicating in a virtual world, tailoring and testing the message with different audiences, and more.

Building Trust and Diversity with Shaka Senghor on Boss Talk #7

content+a16zpodcast@a16z.com (Shaka Senghor, Ben Horowitz, Ali Ghodsi) — Thu, 25 Mar 2021 18:03:37 +0000

Ben and Ali are joined by guest Shaka Senghor, who after 20 years in prison, became an author and activist for prison reform, an entrepreneur, and most recently, head of diversity, equity, and inclusion (DEI) at Tripactions. Shaka shares what prison taught him about building trust in a team, as well as what he sees as the path — and the obstacles— to meaningful diversity in the workplace.

SPACs, Bootstrapping and Funding, Firing Execs, and More on One on One with A and Z #5

content+a16zpodcast@a16z.com (Marc Andreessen, Ben Horowitz) — Wed, 24 Mar 2021 18:58:59 +0000

a16z cofounders Marc Andreessen and Ben Horowitz talk tech trends, company building, and more live on Clubhouse every Monday, 7pm PT.

In this conversation:

How can VCs be both investors and marketing/growth engines for companies they invest in? How has a16z approached this and curating talent on Clubhouse?
Are SPACs the new IPO? What would you say to a founder who pitched you a plan to grow as fast as they can with the goal of selling to a SPAC in 3-5 years?
If a startup is profitably bootstrapping, does it make sense to raise VC money?
How do you fire executives the right way, especially when they own a percent of the company
Can you fire an investor who doesn't align with your company mission or direction?
What tips, tricks, and hacks can help founders maintain their mental health?

Verkada, $16 SMS hacks on Breach of the Week #1

content+a16zpodcast@a16z.com (Joe Sullivan, Geoff Belknap, Joel de la Garza) — Tue, 23 Mar 2021 00:10:30 +0000

🔐Welcome to Breach of the Week 🔐– the show that looks at who got hacked, how it happened, and what it means for the industry. 🎙With hosts Joel de la Garza (a16z Security Operating Partner) and Geoff Belknap (CISO LinkedIn)

👉 On the first episode:

the Verkada hack and the Cloudflare response with Joe Sullivan (CSO Cloudflare)
$16 SMS hacks, how is it possible and what does it mean for SMS?
distracted guard allows intruder into Andrews Air Force Base
Capcom had a breach and made everyone return to the office
a Florida mother and assistant principal hacked the homecoming queen competition so her daughter could win

For more security chatter, Breach of the Week airs on Clubhouse every Thursday 5-5:30pm.

Martin Casado, David Ulevitch, and Ben Horowitz on a16z Infra #1

content+a16zpodcast@a16z.com (David Ulevitch, Martin Casado, Ben Horowitz) — Sat, 20 Mar 2021 03:01:09 +0000

Welcome to a16z Infra, the Clubhouse Show where the a16z enterprise team discusses the foundational technology and products that underpin all of tech. We dig deep into data, AI/ML, security, developer tools, compute, network, storage, hardware, and anything else found below the surface of modern stacks.

On our first show, a16z general partners Ben Horowitz, Martin Casado, and David Ulevitch talk about their journeys as infrastructure founders-turned-investors; what exactly infrastructure is; how it's different from other types of tech; and the importance of technical founders developing go-to-market know-how. Plus, what AWS canceling Parler signals about the state of infrastructure, the impact of cloud costs on margins, and the changing relevance of open source.

Like what you hear? Tune in for our next show with former Microsoft Windows president Steven Sinofsky on Thursday, April 1, 4-5pm.

Internal Comms with Amanda Atkins (Slack) and Shannon Schiltz (a16z) on 4B with Margit #3

Fri, 19 Mar 2021 18:26:07 +0000

Amanda Atkins, who leads Internal Communications & Culture at Slack, and Shannon Schiltz, who heads up HR & People Practices at a16z, talk internal comms with Margit. They break down the basics — When do you need an internal comms function? Where should it report? Is it actually different from external comms — and share advice for the toughest parts of the job, including how to handle layoffs, divisive political issues, negative employee reviews on Glassdoor, and leaks.

4B with Margit is a Clubhouse show for raw and unfiltered advice from comms and marketing experts who have seen it all, as well as insider stories from the builders and pioneers who were in the trenches. Think “Scandal” meets “Halt and Catch Fire.” Catch it live Wednesdays 4-5 PST.

Riccardo Zacconi (Candy Crush Saga) and Kristian Segerstrale (Glu/Playfish) on Games Club

Fri, 19 Mar 2021 16:30:00 +0000

King.com cofounder Riccardo Zacconi (developer of Candy Crush Saga) and Glu/Playfish cofounder Kristian Segerstrale (now the CEO of Super Evil Megacorp) discuss trends in the games industry, failing fast, and building enduring startups with a16z partner Jonathan Lai, Indie MEGABOOTH founder Kelly Wallick, and Stillfront SVP Andrew Green on Games Club.

Greg Reyes on Unfettered Conversations with A and Z

Fri, 19 Mar 2021 03:53:41 +0000

In this occasional Clubhouse series, a16z co-founders Marc Andreessen and Ben Horowitz talk with Greg Reyes, the former CEO of Brocade Communications who was recently pardoned after being convicted of and serving time for the fraudulent backdating of corporate stock options. Greg talks about his career before his conviction, his case and the SEC, his time in prison and what life was like after, the presidential pardon process, his advice for leaders today, and more. Catch Ben and Marc's Clubhouse show live at 7pm PT every Monday.

Pricing Strategy, Category Creation on Boss Talk #6 with Ben Horowitz and Ali Ghodsi

content+a16zpodcast@a16z.com (a16z) — Thu, 18 Mar 2021 17:51:58 +0000

Pricing has huge implications for market size. How do you know if the price isn't right? And when a customer says something is too expensive, what are they really telling you? Also on Boss Talk #6: creating a new category, how Ali learned to handle racism, and when to bet on your next product.

a16z Bio + Health #6: AI for Biologics With Mark DePristo and Peyton Greenside

Thu, 18 Mar 2021 16:00:00 +0000

On this episode of the a16z Bio Clubhouse Show "It's Time to Heal", a16z general partners Vineeta Agarwala, Jorge Conde, Julie Yoo, and Vijay Pande talk to guests Peyton Greenside and Mark DePristo of BigHat Biosciences. The conversation covers the growing role of artificial intelligence and machine learning in drug development and specifically in biologics and protein therapeutics.

Startup Purgatory, Common Pitch Mistakes, Competing with Incumbents and More on One on One with A and Z #4

content+a16zpodcast@a16z.com (Ben Horowitz, Marc Andreessen) — Wed, 17 Mar 2021 00:58:43 +0000

Topics covered this week include:

How to tell if a startup has entered "purgatory", where they're getting by each year but no longer has a chance to be a multi-billion dollar company
Common mistakes founders make when pitching VCs
When do the biggest disagreements happen over possible investments
What happens when an idea is great, but one of the founders is toxic
Is there anyone now like Silicon Valley coaching legend, Coach Bill Campbell?
What kinds of large companies are easiest to compete with?
R&D and basic research, now and then
Investing in people, pre-idea
If you started today with zero connections and $50k in the bank, what would you do?

a16z Bio + Health #5: From COVID to Consumerism & the Future of Virtual First Care with Stephen Klasko

Sat, 13 Mar 2021 11:00:00 +0000

On this episode of the a16z Bio Clubhouse Show "It's Time to Heal", a16z general partners Julie Yoo, Vineeta Agarwala, Jorge Conde, and Vijay Pande, along with market development partner Venkat Mocherla, talk to guest Dr. Stephen Klasko, the president of Thomas Jefferson University and CEO of Jefferson Health about transforming the US healthcare system.

Failure & Comeback with Suneel Gupta et al on 4B with Margit #2

Fri, 12 Mar 2021 22:53:21 +0000

What are the different types of failure? Which can (and can’t) we come back from? And what does it take to turn failure into a comeback story?

The second episode of “4B with Margit” explores failure and comebacks with Suneel Gupta, once a poster child for failure, featured in the New York Times and on the keynote stage of FailCon, whose new book Backable is a study in turning failure into success. Also joining the conversation is Eugene Soltes, Harvard Business School professor and author of Why They Do It: Inside the Mind of the White-Collar Criminal; Ash Spiegelberg, a partner at the Brunswick Group specializing corporate reputation and crisis management; and Carlye Adler, the Silicon Valley ghostwriter who helped Suneel with Backable.

“4B with Margit” is a Clubhouse show for raw and unfiltered advice from comms and marketing experts who have seen it all, as well as insider stories from the builders and pioneers who were in the trenches. Think “Scandal” meets “Halt and Catch Fire.” Catch it live Wednesdays 4-5 PST.

Competing in the Cloud on Boss Talk with Ben Horowitz and Ali Ghodsi

Thu, 11 Mar 2021 17:06:26 +0000

For some cloud software companies, they don't just build on AWS, Azure, or Google Cloud, they compete with them. So, how do you stay ahead when competing in the cloud? a16z cofounder Ben Horowitz and Ali Ghodsi, the Founder/CEO of Databricks, cover that, as well as getting product-market fit on your second product, why it's difficult to do both on-prem and cloud software, the importance of making the right unpopular decision, and how to know if a potential exec hire is a cultural fit on this episode of Boss Talk – the Clubhouse show where a16z cofounder Ben Horowitz and Ali Ghodsi, the Founder/CEO of Databricks, discuss CEO stuff, leadership stuff, management stuff... boss stuff.

a16z Bio + Health #4: The History and Future of Genome Engineering with George Church

Wed, 10 Mar 2021 18:00:00 +0000

On this episode of the a16z Bio Clubhouse Show "It's Time to Heal", a16z general partners Vineeta Agarwala, Jorge Conde, Julie Yoo, and Vijay Pande, along with a16z cofounder Marc Andreessen, talk to guest Dr. George Church of Harvard University about past, future, and power of genome engineering.

a16z Bio + Health #3: Metabolic Health with Casey Means

Tue, 9 Mar 2021 00:02:13 +0000

On this episode of the new a16z Bio Clubhouse Show "It's Time to Heal", a16z general partners Vineeta Agarwala, Jorge Conde, Jeff Jordan, and Vijay Pande, talk to guest Dr. Casey Means, co-founder of Levels Health, about metabolism and metabolic health.

Good Time Show: The NFT Episode

Fri, 5 Mar 2021 22:28:04 +0000

Aarthi Ramamurthy and Sriram Krishnan welcome Marc Andreessen, Chris Dixon, and other experts and early adopters to discuss all things NFT (non-fungible tokens) on the Good Time Show. Guests include Mike Winkelmann (aka Beeple), the digital artist whose work is currently being auctioned at Christie's, and founders of some of the leading digital creative marketplaces including Roham Gharegozlou of Dapper Labs and Kayvon Tehranian of Foundation.

4B with Margit #1

content+a16zpodcast@a16z.com (Marc Andreessen, Margit Wennmachers) — Thu, 4 Mar 2021 23:12:30 +0000

Marc Andreessen joins a16z's Head of Marketing Margit Wennmachers for the first episode of "4B with Margit" — a Clubhouse show for raw and unfiltered advice from comms and marketing experts who have seen it all, as well as insider stories from the builders and pioneers who were in the trenches. Think “Scandal” meets “Halt and Catch Fire.” Catch it live Wednesdays 4-5 PST.

In this episode:

What is a 4B?
What is the playbook for dealing with a crisis? And has it changed with the rise of social media and other direct channels?
How does a company or startup build its media machine? And how should they think about different channels, especially new channels like Clubhouse?
When do you add internal comms? And how do you (or even should you) set a policy for individual employees on social media?

Boss Talk #4

content+a16zpodcast@a16z.com (Ali Ghodsi, Ben Horowitz, Felicia Horowitz) — Thu, 4 Mar 2021 02:56:49 +0000

How do you keep internal politics in check? How do you know when an employee is not working? And how do you maintain culture as you grow? Those questions and more on the fourth episode of Boss Talk, the Clubhouse show where Ben Horowitz and Ali Ghodsi discuss CEO stuff, leadership stuff, management stuff... boss stuff.

Shutdowns, Stimulus Measures, & Small Businesses

content+a16zpodcast@a16z.com (Alex Rampell, Jackie Reses) — Wed, 3 Mar 2021 00:35:00 +0000

a16z general partner Alex Rampell and Post House Capital CEO Jackie Reses (formerly of Square Capital) discuss COVID shutdowns and their impact on small business owners.

a16z Bio + Health #2: Digital Diagnostics with Gaurav Singal

Fri, 26 Feb 2021 00:00:00 +0000

On this episode of the new a16z Bio Clubhouse Show "It's Time to Heal", a16z general partners Vineeta Agarwala, Jorge Conde, Vijay Pande, talk to guest Dr. Gaurav Singal about the future of digital diagnostics: what are they, who stands to benefit from them, and critically, who pays.

Boss Talk #3

content+a16zpodcast@a16z.com (Marc Andreessen, Ali Ghodsi, Ben Horowitz) — Wed, 24 Feb 2021 23:38:09 +0000

Ali shares his early experiences as an Iranian refugee growing up in Sweden and what he learned about leadership. Plus, how technical founders can support and understand sales leaders, striking the balance between sales and marketing, and more on the third episode of Boss Talk – the Clubhouse show where a16z cofounder Ben Horowitz and Ali Ghodsi, the Founder/CEO of Databricks, discuss CEO stuff, leadership stuff, management stuff... boss stuff.

One on One with A and Z #3

content+a16zpodcast@a16z.com (Ben Horowitz, Marc Andreessen, Margit Wennmachers) — Wed, 24 Feb 2021 06:02:25 +0000

Topics covered this week include:

How to handle politics in the workplace
How to avoid hiring talent just like your own
How to have a prepared mind and the "why now" question for startups
Nuclear power and the future of energy
Tech literacy and elected officials
How has their definition of success changed over time
The lessons marriage has taught them about partnerships and vice versa
Science fiction and other book recommendations

Boss Talk #2

Wed, 17 Feb 2021 21:56:05 +0000

Conway’s Law, how to be a boss of bosses, Silicon Valley post-pandemic, and more on the second episode of Boss Talk. The Clubhouse show where a16z cofounder Ben Horowitz and Ali Ghodsi, the Founder/CEO of Databricks, discuss CEO stuff, leadership stuff, management stuff... boss stuff.

One on One with A and Z #2

content+a16zpodcast@a16z.com (Ben Horowitz, Marc Andreessen) — Wed, 17 Feb 2021 01:30:51 +0000

a16z co-founders Marc Andreessen and Ben Horowitz talk about tech trends, company-building, and more in the second episode of their new Clubhouse show, One on One with A and Z. Catch their show live at 7pm PT every Monday.

a16z Bio + Health #1: Things That Make You Go Hmmmm in Healthcare with Nikhil Krishnan

Tue, 16 Feb 2021 05:31:44 +0000

The first episode of the new a16z Bio Clubhouse Show "It's Time to Heal" on a16z Live. a16z General Partners Vineeta Agarwala, Jorge Conde, Vijay Pande, Julie Yoo, and a16z cofounder Marc Andreessen talk to guest Nihkil Krishnan about healthcare—the stuff we're all thinking but don't talk about.

Boss Talk #1

content+a16zpodcast@a16z.com (Ali Ghodsi, Ben Horowitz, Marc Andreessen) — Wed, 10 Feb 2021 22:55:24 +0000

The first episode of the new Clubhouse show Boss Talk, where a16z cofounder Ben Horowitz and Ali Ghodsi, the Founder/CEO of Databricks, discuss CEO stuff, leadership stuff, management stuff... boss stuff.

One on One with A and Z #1

content+a16zpodcast@a16z.com (Marc Andreessen, Ben Horowitz) — Wed, 10 Feb 2021 02:28:35 +0000

a16z co-founders Marc Andreessen and Ben Horowitz talk about tech trends, company-building, and more in the first episode of their new Clubhouse show, One on One with A and Z.

Elon Musk + Vlad Tenev on The Good Time Show

Mon, 1 Feb 2021 07:30:00 +0000

Guests Elon Musk and Vlad Tenev (of Robinhood) join hosts of The Good Time Show on Clubhouse Sriram Krishnan & Aarthi Ramamurthy, Marc Andreessen, Steven Sinofsky, Garry Tan, and others.

Announcing a16z Live

content+a16zpodcast@a16z.com (Sonal Chokshi) — Sat, 30 Jan 2021 03:00:00 +0000

We’re announcing and launching this new feed -- simply called “a16z LIVE” -- for conversations on Clubhouse and beyond.

Our goal is to capture and share many of the live discussions and events featuring, hosted, or co-hosted by a16z partners (with outside voices too); many (though not all) of these different live events take place on the social audio/ drop-in chat app Clubhouse -- to attend those in real time or sign up, please visit joinclubhouse.com.

As a reminder, all the content posted here is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. Views expressed are those of the individuals and not the views of Andreessen Horowitz, please see a16z dot com/ disclosures for more.

Finally: If you’d like to catch other shows on the broader a16z podcast network, be sure to check out the flagship "a16z Podcast", one of the consistently chart-topping shows in tech; our shortform tech trends & news analysis show “16 Minutes”; and our show "Bio Eats World", all about life sciences, healthcare, and technology. All of these are available wherever you get your podcasts. To learn more about the a16z podcast network, please see a16z.com/podnetwork... And feel free to rate and review all our shows as well!